SK19992000A3 - Použitie kyseliny 2-n-propyl-4-hexínovej na liečenie a prevenciu migrény a afektívneho ochorenia - Google Patents
Použitie kyseliny 2-n-propyl-4-hexínovej na liečenie a prevenciu migrény a afektívneho ochorenia Download PDFInfo
- Publication number
- SK19992000A3 SK19992000A3 SK1999-2000A SK19992000A SK19992000A3 SK 19992000 A3 SK19992000 A3 SK 19992000A3 SK 19992000 A SK19992000 A SK 19992000A SK 19992000 A3 SK19992000 A3 SK 19992000A3
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- SK
- Slovakia
- Prior art keywords
- migraine
- propyl
- acid
- valproic acid
- compound
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- 230000011514 reflex Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 239000008109 sodium starch glycolate Substances 0.000 description 1
- 229940079832 sodium starch glycolate Drugs 0.000 description 1
- 229920003109 sodium starch glycolate Polymers 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 239000001593 sorbitan monooleate Substances 0.000 description 1
- 235000011069 sorbitan monooleate Nutrition 0.000 description 1
- 229940035049 sorbitan monooleate Drugs 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100001274 therapeutic index Toxicity 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 239000005526 vasoconstrictor agent Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9028198P | 1998-06-22 | 1998-06-22 | |
| PCT/US1999/014081 WO1999066920A1 (fr) | 1998-06-22 | 1999-06-22 | Utilisation d'un analogue d'acide valproique dans le traitement et la prevention de migraine et de maladies affectives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK19992000A3 true SK19992000A3 (sk) | 2001-08-06 |
Family
ID=22222101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1999-2000A SK19992000A3 (sk) | 1998-06-22 | 1999-06-22 | Použitie kyseliny 2-n-propyl-4-hexínovej na liečenie a prevenciu migrény a afektívneho ochorenia |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6268396B1 (fr) |
| EP (1) | EP1089725A1 (fr) |
| JP (1) | JP2002518442A (fr) |
| KR (1) | KR20010071572A (fr) |
| CN (1) | CN1310622A (fr) |
| AU (2) | AU752192B2 (fr) |
| BG (1) | BG63744B1 (fr) |
| BR (1) | BR9911421A (fr) |
| CA (1) | CA2335641A1 (fr) |
| CZ (1) | CZ20004833A3 (fr) |
| HU (1) | HUP0102456A3 (fr) |
| IL (1) | IL140415A0 (fr) |
| MX (1) | MXPA00012808A (fr) |
| NO (1) | NO20006506L (fr) |
| PL (1) | PL345364A1 (fr) |
| SK (1) | SK19992000A3 (fr) |
| TR (2) | TR200003800T2 (fr) |
| WO (1) | WO1999066920A1 (fr) |
| ZA (1) | ZA200007652B (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6104802A (en) | 1997-02-10 | 2000-08-15 | Genesys Telecommunications Laboratories, Inc. | In-band signaling for routing |
| PT1181012E (pt) | 1999-05-04 | 2005-02-28 | Keith R Edwards | Valproato intravenoso para tratamento de enxaqueca aguda |
| WO2002007677A2 (fr) | 2000-07-21 | 2002-01-31 | Teva Pharmaceutical Industries, Ltd. | Utilisation de derives d'acide valproique et d'amides d'acide 2-valproenique pour le traitement de la manie en cas de desordre bipolaire |
| DE60112766T2 (de) * | 2000-08-17 | 2006-03-30 | Teva Pharmaceutical Industries Ltd. | Verwendung von Derivaten der Valproinsäureamide und 2-Valproinsäureamide zur Behandlung und Prävention von Schmerzen und/oder Kopfschmerzen |
| US20020103110A1 (en) * | 2001-01-26 | 2002-08-01 | Spitzer A. Robert | System and method for rectal administration of medication for treatment of migraines |
| US7968569B2 (en) * | 2002-05-17 | 2011-06-28 | Celgene Corporation | Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione |
| US20060247216A1 (en) * | 2002-10-25 | 2006-11-02 | Haj-Yehia Abdullah I | Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments |
| EP1578413A2 (fr) * | 2002-11-29 | 2005-09-28 | Yissum Research Development Company of The Hebrew University of Jerusalem | Inhibiteurs d'enzyme de conversion de l'angiotensine possedant une activite antioxydante et de donneur d'oxyde nitrique (no) |
| AU2003289782A1 (en) * | 2002-12-16 | 2004-07-09 | The University Of British Columbia | Valproic acid analogues and pharmaceutical compositions thereof |
| EP1543831A1 (fr) * | 2003-12-18 | 2005-06-22 | Pfizer GmbH Arzneimittelwerk Gödecke | Composition de pregabaline |
| WO2006012603A2 (fr) * | 2004-07-22 | 2006-02-02 | Nps Pharmaceuticals, Inc. | Analogues de l'isovaleramide, composition pharmaceutique contenant ces analogues et methode permettant de traiter des maladies ou des affections du systeme nerveux central |
| WO2007028030A2 (fr) * | 2005-09-02 | 2007-03-08 | Picobella, Llc | Arn regulateurs oncogenes pour le diagnostic et la therapie |
| US7459280B2 (en) * | 2006-02-27 | 2008-12-02 | Picobella, Llc | Methods for diagnosing and treating kidney cancer |
| US20080267977A1 (en) * | 2007-04-26 | 2008-10-30 | Friedrich-Alexander University Of Erlangen-Nuremberg | Combined immunological agent and sensitizing agent for the treatment of cancer |
| EP2882427A2 (fr) * | 2012-05-08 | 2015-06-17 | Cellixbio Private Limited | Compositions et méthodes de traitement de troubles neurologiques |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2442M (fr) | 1962-10-17 | 1964-04-06 | Henry Eugene | L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central. |
| US3701729A (en) | 1970-06-01 | 1972-10-31 | Tenneco Chem | Oil-soluble mixed copper soap products |
| US3847956A (en) | 1973-04-06 | 1974-11-12 | Us Agriculture | 2-hydroperoxycarboxylic acids and their preparation |
| US3932285A (en) | 1973-10-03 | 1976-01-13 | Tenneco Chemicals, Inc. | Chromium salt compositions and a process for their production |
| US4025649A (en) | 1974-08-19 | 1977-05-24 | Labaz | Acetic acid derivatives having pharmacological activity and compositions containing the same |
| US4129599A (en) | 1975-04-28 | 1978-12-12 | The Board Of Trustees Of Leland Stanford Jr. University | A-Norsteroids |
| JPS5680116A (en) | 1979-12-05 | 1981-07-01 | Sanyo Electric Co Ltd | Manufacture of substrate for magnetic bubble |
| JPH0233704B2 (ja) | 1982-10-07 | 1990-07-30 | Takeda Chemical Industries Ltd | Chikanbinirukarubonsanjudotai |
| FR2599737B1 (fr) | 1986-06-10 | 1989-05-19 | Sanofi Sa | Procede pour la fixation de groupes alkyles, alkenyles, cycloalkyles ou aralkyles sur une chaine carbonee portant un groupement fonctionnel |
| JPH01135740A (ja) | 1987-11-24 | 1989-05-29 | Nippon Mining Co Ltd | 光学活性を有する２―アルキル―１―アルカン酸の製造方法 |
| US5021398A (en) | 1989-10-26 | 1991-06-04 | Amp Incorporated | Method of forming patterned oxide superconducting films |
| US5102913A (en) * | 1991-07-01 | 1992-04-07 | Halikas James A | Treatment for cocaine use employing valproic acid |
| DE4231085A1 (de) * | 1992-09-12 | 1994-03-17 | Desitin Arzneimittel Gmbh | VPA-analoge Antiepileptika |
| WO1994006456A1 (fr) | 1992-09-16 | 1994-03-31 | Genentech, Inc. | Protection contre des lesions hepatiques au moyen du facteur de croissance d'hepatocytes (hgf) |
| DE69313298T2 (de) | 1992-11-30 | 1998-03-26 | Procter & Gamble | Hochschäumende waschmittelzusammensetzungen mit speziell ausgewählten seifen |
| JP3304459B2 (ja) | 1992-12-18 | 2002-07-22 | 松下電器産業株式会社 | 電解コンデンサ駆動用電解液およびそれを用いた電解コンデンサ |
| TW248552B (fr) | 1993-06-01 | 1995-06-01 | Onoda Yakuhin Kogyo Kk | |
| US5503830A (en) | 1993-09-10 | 1996-04-02 | Petrovax, L.L.C. | Compounds having immunostimulating activity and methods of use thereof |
| WO1995033044A1 (fr) | 1994-05-27 | 1995-12-07 | The Procter & Gamble Company | Compositions detergentes de blanchissage liquides comprenant des savons selectionnes specialement |
| US5681854A (en) | 1995-11-22 | 1997-10-28 | Alcon Laboratories, Inc. | Use of aliphatic carboxylic acid derivatives in ophthalmic disorders |
| IT1283489B1 (it) | 1996-07-23 | 1998-04-21 | Chiesi Farma Spa | Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico |
-
1999
- 1999-06-22 PL PL99345364A patent/PL345364A1/xx not_active Application Discontinuation
- 1999-06-22 IL IL14041599A patent/IL140415A0/xx unknown
- 1999-06-22 WO PCT/US1999/014081 patent/WO1999066920A1/fr not_active Application Discontinuation
- 1999-06-22 JP JP2000555606A patent/JP2002518442A/ja active Pending
- 1999-06-22 US US09/337,986 patent/US6268396B1/en not_active Expired - Fee Related
- 1999-06-22 EP EP99930555A patent/EP1089725A1/fr not_active Withdrawn
- 1999-06-22 TR TR2000/03800T patent/TR200003800T2/xx unknown
- 1999-06-22 BR BR9911421-6A patent/BR9911421A/pt not_active IP Right Cessation
- 1999-06-22 MX MXPA00012808A patent/MXPA00012808A/es unknown
- 1999-06-22 CA CA002335641A patent/CA2335641A1/fr not_active Abandoned
- 1999-06-22 SK SK1999-2000A patent/SK19992000A3/sk unknown
- 1999-06-22 AU AU47071/99A patent/AU752192B2/en not_active Ceased
- 1999-06-22 KR KR1020007014630A patent/KR20010071572A/ko not_active Application Discontinuation
- 1999-06-22 CN CN99808955A patent/CN1310622A/zh active Pending
- 1999-06-22 CZ CZ20004833A patent/CZ20004833A3/cs unknown
- 1999-06-22 HU HU0102456A patent/HUP0102456A3/hu unknown
- 1999-06-27 TR TR2001/03249T patent/TR200103249T2/xx unknown
- 1999-06-28 AU AU52071/99A patent/AU5207199A/en not_active Abandoned
-
2000
- 2000-12-19 ZA ZA200007652A patent/ZA200007652B/en unknown
- 2000-12-20 NO NO20006506A patent/NO20006506L/no not_active Application Discontinuation
-
2001
- 2001-01-17 BG BG105163A patent/BG63744B1/bg unknown
- 2001-04-23 US US09/840,376 patent/US6458840B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| TR200103249T2 (tr) | 2002-05-21 |
| BG63744B1 (bg) | 2002-11-29 |
| MXPA00012808A (es) | 2002-04-24 |
| US20010031789A1 (en) | 2001-10-18 |
| AU752192B2 (en) | 2002-09-12 |
| NO20006506L (no) | 2001-02-21 |
| PL345364A1 (en) | 2001-12-17 |
| AU5207199A (en) | 2000-01-24 |
| CA2335641A1 (fr) | 1999-12-29 |
| TR200003800T2 (tr) | 2001-06-21 |
| KR20010071572A (ko) | 2001-07-28 |
| JP2002518442A (ja) | 2002-06-25 |
| ZA200007652B (en) | 2002-03-19 |
| NO20006506D0 (no) | 2000-12-20 |
| BG105163A (en) | 2002-03-29 |
| HUP0102456A2 (hu) | 2001-10-28 |
| CZ20004833A3 (cs) | 2002-01-16 |
| AU4707199A (en) | 2000-01-10 |
| IL140415A0 (en) | 2002-02-10 |
| BR9911421A (pt) | 2001-03-27 |
| US6268396B1 (en) | 2001-07-31 |
| US6458840B2 (en) | 2002-10-01 |
| CN1310622A (zh) | 2001-08-29 |
| EP1089725A1 (fr) | 2001-04-11 |
| HUP0102456A3 (en) | 2003-07-28 |
| WO1999066920A1 (fr) | 1999-12-29 |
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