TR200103249T2 - Migrenin tedavisi ve önlenmesinde valproik asit analoğu kullanımı. - Google Patents
Migrenin tedavisi ve önlenmesinde valproik asit analoğu kullanımı.Info
- Publication number
- TR200103249T2 TR200103249T2 TR2001/03249T TR200103249T TR200103249T2 TR 200103249 T2 TR200103249 T2 TR 200103249T2 TR 2001/03249 T TR2001/03249 T TR 2001/03249T TR 200103249 T TR200103249 T TR 200103249T TR 200103249 T2 TR200103249 T2 TR 200103249T2
- Authority
- TR
- Turkey
- Prior art keywords
- migraine
- prevention
- treatment
- valproic acid
- acid analogues
- Prior art date
Links
- NIJJYAXOARWZEE-UHFFFAOYSA-N Valproic acid Chemical class CCCC(C(O)=O)CCC NIJJYAXOARWZEE-UHFFFAOYSA-N 0.000 title abstract 3
- 208000019695 Migraine disease Diseases 0.000 title abstract 2
- 206010027599 migraine Diseases 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 206010029350 Neurotoxicity Diseases 0.000 abstract 1
- 206010044221 Toxic encephalopathy Diseases 0.000 abstract 1
- 230000002460 anti-migrenic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000007135 neurotoxicity Effects 0.000 abstract 1
- 231100000228 neurotoxicity Toxicity 0.000 abstract 1
- 231100000378 teratogenic Toxicity 0.000 abstract 1
- 230000003390 teratogenic effect Effects 0.000 abstract 1
- 229960000604 valproic acid Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Bu bulus, migren ve cinnet hastaliklarin tedavisi ve önlenmesine yönelik bir ilaç imalati için valproik asit benzeri olan 2-n-propil-4-heksinoik asidin kullanimi ile ilgilidir. 2-n-propil-4-heksinoik asit bilesigi, valproik asitle kiyaslandiginda, nörotoksisite ve teratojenik potansiyel gibi yan etkileri büyük ölçüde düsürülmüs etkili bir anti-migren ve anti-cinnet hastaligi ilacidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9028198P | 1998-06-22 | 1998-06-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200103249T2 true TR200103249T2 (tr) | 2002-05-21 |
Family
ID=22222101
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/03800T TR200003800T2 (tr) | 1998-06-22 | 1999-06-22 | Migrenin tedavisi ve önlenmesinde valproik asit analoğu kullanımı |
TR2001/03249T TR200103249T2 (tr) | 1998-06-22 | 1999-06-27 | Migrenin tedavisi ve önlenmesinde valproik asit analoğu kullanımı. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/03800T TR200003800T2 (tr) | 1998-06-22 | 1999-06-22 | Migrenin tedavisi ve önlenmesinde valproik asit analoğu kullanımı |
Country Status (19)
Country | Link |
---|---|
US (2) | US6268396B1 (tr) |
EP (1) | EP1089725A1 (tr) |
JP (1) | JP2002518442A (tr) |
KR (1) | KR20010071572A (tr) |
CN (1) | CN1310622A (tr) |
AU (2) | AU752192B2 (tr) |
BG (1) | BG63744B1 (tr) |
BR (1) | BR9911421A (tr) |
CA (1) | CA2335641A1 (tr) |
CZ (1) | CZ20004833A3 (tr) |
HU (1) | HUP0102456A3 (tr) |
IL (1) | IL140415A0 (tr) |
MX (1) | MXPA00012808A (tr) |
NO (1) | NO20006506L (tr) |
PL (1) | PL345364A1 (tr) |
SK (1) | SK19992000A3 (tr) |
TR (2) | TR200003800T2 (tr) |
WO (1) | WO1999066920A1 (tr) |
ZA (1) | ZA200007652B (tr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6104802A (en) | 1997-02-10 | 2000-08-15 | Genesys Telecommunications Laboratories, Inc. | In-band signaling for routing |
WO2000066109A2 (en) * | 1999-05-04 | 2000-11-09 | Edwards Keith R | Intravenous valproate for acute treatment of migraine headache |
NZ523917A (en) * | 2000-07-21 | 2004-11-26 | Teva Pharma | Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder |
AU8830801A (en) * | 2000-08-17 | 2002-02-25 | Teva Pharma | Use of derivatives of valproic acid amides and 2-valproenic acid amides for the treatment or prevention of pain and/or headache disorders |
US20020103110A1 (en) * | 2001-01-26 | 2002-08-01 | Spitzer A. Robert | System and method for rectal administration of medication for treatment of migraines |
US7968569B2 (en) * | 2002-05-17 | 2011-06-28 | Celgene Corporation | Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione |
EP1562975A2 (en) * | 2002-10-25 | 2005-08-17 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments |
US20060166894A1 (en) * | 2002-11-29 | 2006-07-27 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Ace-inhibitors having antioxidant and no-donor activity |
US20060223888A1 (en) * | 2002-12-16 | 2006-10-05 | Abbott Frank S | Valproic acid analogues and pharmaceutical composition thereof |
EP1543831A1 (en) * | 2003-12-18 | 2005-06-22 | Pfizer GmbH Arzneimittelwerk Gödecke | Pregabalin composition |
WO2006012603A2 (en) * | 2004-07-22 | 2006-02-02 | Nps Pharmaceuticals, Inc. | Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases |
US20080234213A1 (en) * | 2005-09-02 | 2008-09-25 | Matthias Wabl | Oncogenic regulatory RNAs for diagnostics and therapeutics |
US7459280B2 (en) * | 2006-02-27 | 2008-12-02 | Picobella, Llc | Methods for diagnosing and treating kidney cancer |
US20080267977A1 (en) * | 2007-04-26 | 2008-10-30 | Friedrich-Alexander University Of Erlangen-Nuremberg | Combined immunological agent and sensitizing agent for the treatment of cancer |
CN104797568A (zh) * | 2012-05-08 | 2015-07-22 | 塞利克斯比奥私人有限公司 | 用于治疗神经障碍的组合物和方法 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2442M (fr) | 1962-10-17 | 1964-04-06 | Henry Eugene | L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central. |
US3701729A (en) | 1970-06-01 | 1972-10-31 | Tenneco Chem | Oil-soluble mixed copper soap products |
US3847956A (en) | 1973-04-06 | 1974-11-12 | Us Agriculture | 2-hydroperoxycarboxylic acids and their preparation |
US3932285A (en) | 1973-10-03 | 1976-01-13 | Tenneco Chemicals, Inc. | Chromium salt compositions and a process for their production |
US4025649A (en) | 1974-08-19 | 1977-05-24 | Labaz | Acetic acid derivatives having pharmacological activity and compositions containing the same |
US4129599A (en) | 1975-04-28 | 1978-12-12 | The Board Of Trustees Of Leland Stanford Jr. University | A-Norsteroids |
JPS5680116A (en) | 1979-12-05 | 1981-07-01 | Sanyo Electric Co Ltd | Manufacture of substrate for magnetic bubble |
JPH0233704B2 (ja) | 1982-10-07 | 1990-07-30 | Takeda Chemical Industries Ltd | Chikanbinirukarubonsanjudotai |
FR2599737B1 (fr) | 1986-06-10 | 1989-05-19 | Sanofi Sa | Procede pour la fixation de groupes alkyles, alkenyles, cycloalkyles ou aralkyles sur une chaine carbonee portant un groupement fonctionnel |
JPH01135740A (ja) | 1987-11-24 | 1989-05-29 | Nippon Mining Co Ltd | 光学活性を有する2―アルキル―1―アルカン酸の製造方法 |
US5021398A (en) | 1989-10-26 | 1991-06-04 | Amp Incorporated | Method of forming patterned oxide superconducting films |
US5102913A (en) * | 1991-07-01 | 1992-04-07 | Halikas James A | Treatment for cocaine use employing valproic acid |
DE4231085A1 (de) * | 1992-09-12 | 1994-03-17 | Desitin Arzneimittel Gmbh | VPA-analoge Antiepileptika |
DE69310525T2 (de) | 1992-09-16 | 1997-10-02 | Genentech Inc | Schutz gegen leberschäden mit hgf |
JPH08503732A (ja) | 1992-11-30 | 1996-04-23 | ザ、プロクター、エンド、ギャンブル、カンパニー | 特選の石鹸を含有する高起泡性洗剤組成物 |
JP3304459B2 (ja) | 1992-12-18 | 2002-07-22 | 松下電器産業株式会社 | 電解コンデンサ駆動用電解液およびそれを用いた電解コンデンサ |
EP0632008B1 (en) | 1993-06-01 | 1998-02-04 | Ono Pharmaceutical Co., Ltd. | Pentanoic acid derivatives |
US5503830A (en) | 1993-09-10 | 1996-04-02 | Petrovax, L.L.C. | Compounds having immunostimulating activity and methods of use thereof |
WO1995033044A1 (en) | 1994-05-27 | 1995-12-07 | The Procter & Gamble Company | Liquid laundry detergent compositions comprising specially selected soaps |
US5681854A (en) | 1995-11-22 | 1997-10-28 | Alcon Laboratories, Inc. | Use of aliphatic carboxylic acid derivatives in ophthalmic disorders |
IT1283489B1 (it) | 1996-07-23 | 1998-04-21 | Chiesi Farma Spa | Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico |
-
1999
- 1999-06-22 BR BR9911421-6A patent/BR9911421A/pt not_active IP Right Cessation
- 1999-06-22 EP EP99930555A patent/EP1089725A1/en not_active Withdrawn
- 1999-06-22 US US09/337,986 patent/US6268396B1/en not_active Expired - Fee Related
- 1999-06-22 CN CN99808955A patent/CN1310622A/zh active Pending
- 1999-06-22 TR TR2000/03800T patent/TR200003800T2/tr unknown
- 1999-06-22 HU HU0102456A patent/HUP0102456A3/hu unknown
- 1999-06-22 CZ CZ20004833A patent/CZ20004833A3/cs unknown
- 1999-06-22 WO PCT/US1999/014081 patent/WO1999066920A1/en not_active Application Discontinuation
- 1999-06-22 JP JP2000555606A patent/JP2002518442A/ja active Pending
- 1999-06-22 CA CA002335641A patent/CA2335641A1/en not_active Abandoned
- 1999-06-22 KR KR1020007014630A patent/KR20010071572A/ko not_active Application Discontinuation
- 1999-06-22 SK SK1999-2000A patent/SK19992000A3/sk unknown
- 1999-06-22 IL IL14041599A patent/IL140415A0/xx unknown
- 1999-06-22 MX MXPA00012808A patent/MXPA00012808A/es unknown
- 1999-06-22 PL PL99345364A patent/PL345364A1/xx not_active Application Discontinuation
- 1999-06-22 AU AU47071/99A patent/AU752192B2/en not_active Ceased
- 1999-06-27 TR TR2001/03249T patent/TR200103249T2/tr unknown
- 1999-06-28 AU AU52071/99A patent/AU5207199A/en not_active Abandoned
-
2000
- 2000-12-19 ZA ZA200007652A patent/ZA200007652B/en unknown
- 2000-12-20 NO NO20006506A patent/NO20006506L/no not_active Application Discontinuation
-
2001
- 2001-01-17 BG BG105163A patent/BG63744B1/bg unknown
- 2001-04-23 US US09/840,376 patent/US6458840B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1999066920A1 (en) | 1999-12-29 |
KR20010071572A (ko) | 2001-07-28 |
US20010031789A1 (en) | 2001-10-18 |
AU752192B2 (en) | 2002-09-12 |
PL345364A1 (en) | 2001-12-17 |
AU5207199A (en) | 2000-01-24 |
NO20006506D0 (no) | 2000-12-20 |
SK19992000A3 (sk) | 2001-08-06 |
CA2335641A1 (en) | 1999-12-29 |
AU4707199A (en) | 2000-01-10 |
US6268396B1 (en) | 2001-07-31 |
IL140415A0 (en) | 2002-02-10 |
BG63744B1 (bg) | 2002-11-29 |
US6458840B2 (en) | 2002-10-01 |
TR200003800T2 (tr) | 2001-06-21 |
MXPA00012808A (es) | 2002-04-24 |
CZ20004833A3 (cs) | 2002-01-16 |
BG105163A (en) | 2002-03-29 |
HUP0102456A3 (en) | 2003-07-28 |
NO20006506L (no) | 2001-02-21 |
BR9911421A (pt) | 2001-03-27 |
JP2002518442A (ja) | 2002-06-25 |
ZA200007652B (en) | 2002-03-19 |
EP1089725A1 (en) | 2001-04-11 |
HUP0102456A2 (hu) | 2001-10-28 |
CN1310622A (zh) | 2001-08-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TR200103249T2 (tr) | Migrenin tedavisi ve önlenmesinde valproik asit analoğu kullanımı. | |
DE69920757D1 (de) | Immunsuppressive wirkungen von pteridinderivaten | |
CY1118363T1 (el) | Αντισωματα που ανοσοειδικως συνδεονται προς blys | |
CY1109242T1 (el) | Θεραπευτικοι παραγοντες χρησιμοι για θεραπεια πονου | |
DE50310516D1 (de) | Fredericamycin-derivate | |
DK1390378T3 (da) | Farmaceutisk aktive uridin estere | |
EA200000911A1 (ru) | Новые кристаллические формы антивирусного соединения бензимидазола | |
BR9806752A (pt) | Ftalazinonas. | |
HK1069339A1 (en) | Substituted diketopiperazines as oxytocin antagonists | |
DE60315964D1 (de) | Verbesserung der herstellung von endogenen gonadotropin | |
SE0301886D0 (sv) | New use V | |
TR200401029T4 (tr) | Asilfenil-üre türevleri, imalat yöntemleri ve ilaç maddesi olarak kullanımları | |
HN1999000045A (es) | Derivados biciclicos del acido hidroxamico | |
ATE450265T1 (de) | Pharmazeutische mischung zur behandlung von krebs,die dioxolan nukleosidanalogen enthält | |
TR200103233T2 (tr) | Antikolinerjik etkili bileşik ve ß-mimetikler bazında yeni ilaç bileşimleri. | |
SE0301882D0 (sv) | New use I | |
BR0007527A (pt) | Fenilfenantridinas com atividade inibitória depde-iv | |
ID29107A (id) | Metoda pengobatan iskemia serebral dan penggunaannya eritropoetin atau turunan eritropoetin untuk penggunaan iskemia serebral | |
EA200200616A1 (ru) | Химические производные и их применение в качестве антителомеразного агента | |
EA200501105A1 (ru) | Фармацевтическая композиция | |
PT1390371E (pt) | Oxazolo- e furopirimidinas e sua utilizacao em medicamentos contra tumores | |
NO20024646D0 (no) | Kombinasjonsterapier med vaskul¶r-skadende aktivitet | |
BR0107628A (pt) | l,2-diarilbenzimidazóis para tratamento de doenças que estão associadas a uma ativação microglial | |
TR200002837T2 (tr) | Yoğun bakım ünitesindeki ağrı kesme işlemi için deksmedetomidinin kullanımı | |
NO20020829L (no) | Ny anvendelse av docetaxel for behandling av hepatoma |