TR200103249T2 - Migrenin tedavisi ve önlenmesinde valproik asit analoğu kullanımı. - Google Patents

Migrenin tedavisi ve önlenmesinde valproik asit analoğu kullanımı.

Info

Publication number
TR200103249T2
TR200103249T2 TR2001/03249T TR200103249T TR200103249T2 TR 200103249 T2 TR200103249 T2 TR 200103249T2 TR 2001/03249 T TR2001/03249 T TR 2001/03249T TR 200103249 T TR200103249 T TR 200103249T TR 200103249 T2 TR200103249 T2 TR 200103249T2
Authority
TR
Turkey
Prior art keywords
migraine
prevention
treatment
valproic acid
acid analogues
Prior art date
Application number
TR2001/03249T
Other languages
English (en)
Inventor
Nau Heinz
Leahy Emer
O'conell Alan
Original Assignee
American Biogenetic Sciences, Inc.
Nau Heinz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Biogenetic Sciences, Inc., Nau Heinz filed Critical American Biogenetic Sciences, Inc.
Publication of TR200103249T2 publication Critical patent/TR200103249T2/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Bu bulus, migren ve cinnet hastaliklarin tedavisi ve önlenmesine yönelik bir ilaç imalati için valproik asit benzeri olan 2-n-propil-4-heksinoik asidin kullanimi ile ilgilidir. 2-n-propil-4-heksinoik asit bilesigi, valproik asitle kiyaslandiginda, nörotoksisite ve teratojenik potansiyel gibi yan etkileri büyük ölçüde düsürülmüs etkili bir anti-migren ve anti-cinnet hastaligi ilacidir.
TR2001/03249T 1998-06-22 1999-06-27 Migrenin tedavisi ve önlenmesinde valproik asit analoğu kullanımı. TR200103249T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9028198P 1998-06-22 1998-06-22

Publications (1)

Publication Number Publication Date
TR200103249T2 true TR200103249T2 (tr) 2002-05-21

Family

ID=22222101

Family Applications (2)

Application Number Title Priority Date Filing Date
TR2000/03800T TR200003800T2 (tr) 1998-06-22 1999-06-22 Migrenin tedavisi ve önlenmesinde valproik asit analoğu kullanımı
TR2001/03249T TR200103249T2 (tr) 1998-06-22 1999-06-27 Migrenin tedavisi ve önlenmesinde valproik asit analoğu kullanımı.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TR2000/03800T TR200003800T2 (tr) 1998-06-22 1999-06-22 Migrenin tedavisi ve önlenmesinde valproik asit analoğu kullanımı

Country Status (19)

Country Link
US (2) US6268396B1 (tr)
EP (1) EP1089725A1 (tr)
JP (1) JP2002518442A (tr)
KR (1) KR20010071572A (tr)
CN (1) CN1310622A (tr)
AU (2) AU752192B2 (tr)
BG (1) BG63744B1 (tr)
BR (1) BR9911421A (tr)
CA (1) CA2335641A1 (tr)
CZ (1) CZ20004833A3 (tr)
HU (1) HUP0102456A3 (tr)
IL (1) IL140415A0 (tr)
MX (1) MXPA00012808A (tr)
NO (1) NO20006506L (tr)
PL (1) PL345364A1 (tr)
SK (1) SK19992000A3 (tr)
TR (2) TR200003800T2 (tr)
WO (1) WO1999066920A1 (tr)
ZA (1) ZA200007652B (tr)

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US6104802A (en) 1997-02-10 2000-08-15 Genesys Telecommunications Laboratories, Inc. In-band signaling for routing
WO2000066109A2 (en) * 1999-05-04 2000-11-09 Edwards Keith R Intravenous valproate for acute treatment of migraine headache
NZ523917A (en) * 2000-07-21 2004-11-26 Teva Pharma Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder
AU8830801A (en) * 2000-08-17 2002-02-25 Teva Pharma Use of derivatives of valproic acid amides and 2-valproenic acid amides for the treatment or prevention of pain and/or headache disorders
US20020103110A1 (en) * 2001-01-26 2002-08-01 Spitzer A. Robert System and method for rectal administration of medication for treatment of migraines
US7968569B2 (en) * 2002-05-17 2011-06-28 Celgene Corporation Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
EP1562975A2 (en) * 2002-10-25 2005-08-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments
US20060166894A1 (en) * 2002-11-29 2006-07-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ace-inhibitors having antioxidant and no-donor activity
US20060223888A1 (en) * 2002-12-16 2006-10-05 Abbott Frank S Valproic acid analogues and pharmaceutical composition thereof
EP1543831A1 (en) * 2003-12-18 2005-06-22 Pfizer GmbH Arzneimittelwerk Gödecke Pregabalin composition
WO2006012603A2 (en) * 2004-07-22 2006-02-02 Nps Pharmaceuticals, Inc. Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases
US20080234213A1 (en) * 2005-09-02 2008-09-25 Matthias Wabl Oncogenic regulatory RNAs for diagnostics and therapeutics
US7459280B2 (en) * 2006-02-27 2008-12-02 Picobella, Llc Methods for diagnosing and treating kidney cancer
US20080267977A1 (en) * 2007-04-26 2008-10-30 Friedrich-Alexander University Of Erlangen-Nuremberg Combined immunological agent and sensitizing agent for the treatment of cancer
CN104797568A (zh) * 2012-05-08 2015-07-22 塞利克斯比奥私人有限公司 用于治疗神经障碍的组合物和方法

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FR2442M (fr) 1962-10-17 1964-04-06 Henry Eugene L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central.
US3701729A (en) 1970-06-01 1972-10-31 Tenneco Chem Oil-soluble mixed copper soap products
US3847956A (en) 1973-04-06 1974-11-12 Us Agriculture 2-hydroperoxycarboxylic acids and their preparation
US3932285A (en) 1973-10-03 1976-01-13 Tenneco Chemicals, Inc. Chromium salt compositions and a process for their production
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US4129599A (en) 1975-04-28 1978-12-12 The Board Of Trustees Of Leland Stanford Jr. University A-Norsteroids
JPS5680116A (en) 1979-12-05 1981-07-01 Sanyo Electric Co Ltd Manufacture of substrate for magnetic bubble
JPH0233704B2 (ja) 1982-10-07 1990-07-30 Takeda Chemical Industries Ltd Chikanbinirukarubonsanjudotai
FR2599737B1 (fr) 1986-06-10 1989-05-19 Sanofi Sa Procede pour la fixation de groupes alkyles, alkenyles, cycloalkyles ou aralkyles sur une chaine carbonee portant un groupement fonctionnel
JPH01135740A (ja) 1987-11-24 1989-05-29 Nippon Mining Co Ltd 光学活性を有する2―アルキル―1―アルカン酸の製造方法
US5021398A (en) 1989-10-26 1991-06-04 Amp Incorporated Method of forming patterned oxide superconducting films
US5102913A (en) * 1991-07-01 1992-04-07 Halikas James A Treatment for cocaine use employing valproic acid
DE4231085A1 (de) * 1992-09-12 1994-03-17 Desitin Arzneimittel Gmbh VPA-analoge Antiepileptika
DE69310525T2 (de) 1992-09-16 1997-10-02 Genentech Inc Schutz gegen leberschäden mit hgf
JPH08503732A (ja) 1992-11-30 1996-04-23 ザ、プロクター、エンド、ギャンブル、カンパニー 特選の石鹸を含有する高起泡性洗剤組成物
JP3304459B2 (ja) 1992-12-18 2002-07-22 松下電器産業株式会社 電解コンデンサ駆動用電解液およびそれを用いた電解コンデンサ
EP0632008B1 (en) 1993-06-01 1998-02-04 Ono Pharmaceutical Co., Ltd. Pentanoic acid derivatives
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IT1283489B1 (it) 1996-07-23 1998-04-21 Chiesi Farma Spa Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico

Also Published As

Publication number Publication date
WO1999066920A1 (en) 1999-12-29
KR20010071572A (ko) 2001-07-28
US20010031789A1 (en) 2001-10-18
AU752192B2 (en) 2002-09-12
PL345364A1 (en) 2001-12-17
AU5207199A (en) 2000-01-24
NO20006506D0 (no) 2000-12-20
SK19992000A3 (sk) 2001-08-06
CA2335641A1 (en) 1999-12-29
AU4707199A (en) 2000-01-10
US6268396B1 (en) 2001-07-31
IL140415A0 (en) 2002-02-10
BG63744B1 (bg) 2002-11-29
US6458840B2 (en) 2002-10-01
TR200003800T2 (tr) 2001-06-21
MXPA00012808A (es) 2002-04-24
CZ20004833A3 (cs) 2002-01-16
BG105163A (en) 2002-03-29
HUP0102456A3 (en) 2003-07-28
NO20006506L (no) 2001-02-21
BR9911421A (pt) 2001-03-27
JP2002518442A (ja) 2002-06-25
ZA200007652B (en) 2002-03-19
EP1089725A1 (en) 2001-04-11
HUP0102456A2 (hu) 2001-10-28
CN1310622A (zh) 2001-08-29

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