BR9911421A - Uso de análogo do ácido valpróico para o tratamento e prevenção da enxaqueca e doenças emocionais - Google Patents

Uso de análogo do ácido valpróico para o tratamento e prevenção da enxaqueca e doenças emocionais

Info

Publication number
BR9911421A
BR9911421A BR9911421-6A BR9911421A BR9911421A BR 9911421 A BR9911421 A BR 9911421A BR 9911421 A BR9911421 A BR 9911421A BR 9911421 A BR9911421 A BR 9911421A
Authority
BR
Brazil
Prior art keywords
migraine
emotional
prevention
treatment
acid
Prior art date
Application number
BR9911421-6A
Other languages
English (en)
Inventor
Heinz Nau
Emer Leahy
Alan O'connell
Original Assignee
American Biogenetic Sciences
Heinz Nau
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Biogenetic Sciences, Heinz Nau filed Critical American Biogenetic Sciences
Publication of BR9911421A publication Critical patent/BR9911421A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"USO DE ANáLOGO DO áCIDO VALPRóICO PARA O TRATAMENTO E PREVENçãO DA ENXAQUECA E DOENçAS EMOCIONAIS" Esta invenção se refere a um método para o tratamento e prevenção da enxaqueca e doenças emocionais através da administração de uma quantidade terapeuticamente efetiva do ácido 2-n-propil-4-hexinóico análogo do ácido valpróico. O composto ácido 2-n-propil-4-hexinóico é uma efetiva droga anti-enxaqueca e anti-doença emocional com efeitos adversos grandemente reduzidos incluindo a neurotoxicidade e o potencial teratogênico comparado ao ácido valpróico. Esta invenção portanto proporciona um método aprimorado para o tratamento e prevenção da enxaqueca e doenças emocionais.
BR9911421-6A 1998-06-22 1999-06-22 Uso de análogo do ácido valpróico para o tratamento e prevenção da enxaqueca e doenças emocionais BR9911421A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9028198P 1998-06-22 1998-06-22
PCT/US1999/014081 WO1999066920A1 (en) 1998-06-22 1999-06-22 The use of valproic acid analog for the treatment and prevention of migraine and affective illness

Publications (1)

Publication Number Publication Date
BR9911421A true BR9911421A (pt) 2001-03-27

Family

ID=22222101

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9911421-6A BR9911421A (pt) 1998-06-22 1999-06-22 Uso de análogo do ácido valpróico para o tratamento e prevenção da enxaqueca e doenças emocionais

Country Status (19)

Country Link
US (2) US6268396B1 (pt)
EP (1) EP1089725A1 (pt)
JP (1) JP2002518442A (pt)
KR (1) KR20010071572A (pt)
CN (1) CN1310622A (pt)
AU (2) AU752192B2 (pt)
BG (1) BG63744B1 (pt)
BR (1) BR9911421A (pt)
CA (1) CA2335641A1 (pt)
CZ (1) CZ20004833A3 (pt)
HU (1) HUP0102456A3 (pt)
IL (1) IL140415A0 (pt)
MX (1) MXPA00012808A (pt)
NO (1) NO20006506L (pt)
PL (1) PL345364A1 (pt)
SK (1) SK19992000A3 (pt)
TR (2) TR200003800T2 (pt)
WO (1) WO1999066920A1 (pt)
ZA (1) ZA200007652B (pt)

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US6104802A (en) 1997-02-10 2000-08-15 Genesys Telecommunications Laboratories, Inc. In-band signaling for routing
CA2372806A1 (en) * 1999-05-04 2000-11-09 Keith R. Edwards Intravenous valproate for acute treatment of migraine headache
KR100843703B1 (ko) 2000-07-21 2008-07-04 이섬 리서치 디벨러프먼트 컴파니 오브 더 히브루 유니버시티 오브 예루살렘 양극성 장애에서의 조증을 치료하기 위한 벨프로익산 및 2-벨프로에닉산 아미드 유도체의 용도
MXPA03001458A (es) * 2000-08-17 2004-05-04 Teva Pharma Derivados de acido valproico para el tratamiento del dolor.
US20020103110A1 (en) * 2001-01-26 2002-08-01 Spitzer A. Robert System and method for rectal administration of medication for treatment of migraines
US7968569B2 (en) * 2002-05-17 2011-06-28 Celgene Corporation Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
WO2004037843A2 (en) * 2002-10-25 2004-05-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments
WO2004050084A2 (en) * 2002-11-29 2004-06-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ace-inhibitors having antioxidant and nitricoxid-donor activity
CA2508855A1 (en) * 2002-12-16 2004-07-01 Frank Slade Abbott Valproic acid analogues and pharmaceutical compositions thereof
EP1543831A1 (en) * 2003-12-18 2005-06-22 Pfizer GmbH Arzneimittelwerk Gödecke Pregabalin composition
WO2006012603A2 (en) * 2004-07-22 2006-02-02 Nps Pharmaceuticals, Inc. Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases
US20080234213A1 (en) * 2005-09-02 2008-09-25 Matthias Wabl Oncogenic regulatory RNAs for diagnostics and therapeutics
US7459280B2 (en) * 2006-02-27 2008-12-02 Picobella, Llc Methods for diagnosing and treating kidney cancer
US20080267977A1 (en) * 2007-04-26 2008-10-30 Friedrich-Alexander University Of Erlangen-Nuremberg Combined immunological agent and sensitizing agent for the treatment of cancer
AU2013257710B2 (en) * 2012-05-08 2016-10-20 Cellixbio Private Limited Compositions and methods for the treatment of neurological disorders

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FR2442M (fr) 1962-10-17 1964-04-06 Henry Eugene L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central.
US3701729A (en) 1970-06-01 1972-10-31 Tenneco Chem Oil-soluble mixed copper soap products
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FR2599737B1 (fr) 1986-06-10 1989-05-19 Sanofi Sa Procede pour la fixation de groupes alkyles, alkenyles, cycloalkyles ou aralkyles sur une chaine carbonee portant un groupement fonctionnel
JPH01135740A (ja) 1987-11-24 1989-05-29 Nippon Mining Co Ltd 光学活性を有する２―アルキル―１―アルカン酸の製造方法
US5021398A (en) 1989-10-26 1991-06-04 Amp Incorporated Method of forming patterned oxide superconducting films
US5102913A (en) * 1991-07-01 1992-04-07 Halikas James A Treatment for cocaine use employing valproic acid
DE4231085A1 (de) * 1992-09-12 1994-03-17 Desitin Arzneimittel Gmbh VPA-analoge Antiepileptika
EP0661993B1 (en) 1992-09-16 1997-05-07 Genentech, Inc. Protection against liver damage by hgf
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Also Published As

Publication number Publication date
KR20010071572A (ko) 2001-07-28
CZ20004833A3 (cs) 2002-01-16
EP1089725A1 (en) 2001-04-11
NO20006506L (no) 2001-02-21
PL345364A1 (en) 2001-12-17
NO20006506D0 (no) 2000-12-20
AU752192B2 (en) 2002-09-12
CN1310622A (zh) 2001-08-29
AU4707199A (en) 2000-01-10
MXPA00012808A (es) 2002-04-24
HUP0102456A2 (hu) 2001-10-28
CA2335641A1 (en) 1999-12-29
SK19992000A3 (sk) 2001-08-06
IL140415A0 (en) 2002-02-10
US6268396B1 (en) 2001-07-31
ZA200007652B (en) 2002-03-19
TR200103249T2 (tr) 2002-05-21
TR200003800T2 (tr) 2001-06-21
HUP0102456A3 (en) 2003-07-28
BG105163A (en) 2002-03-29
WO1999066920A1 (en) 1999-12-29
JP2002518442A (ja) 2002-06-25
BG63744B1 (bg) 2002-11-29
AU5207199A (en) 2000-01-24
US6458840B2 (en) 2002-10-01
US20010031789A1 (en) 2001-10-18

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5,6,7 E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007.