BR9915267A - Métodos de tratamento, prevenção ou redução derisco de doença de alzheimer - Google Patents
Métodos de tratamento, prevenção ou redução derisco de doença de alzheimerInfo
- Publication number
- BR9915267A BR9915267A BR9915267-3A BR9915267A BR9915267A BR 9915267 A BR9915267 A BR 9915267A BR 9915267 A BR9915267 A BR 9915267A BR 9915267 A BR9915267 A BR 9915267A
- Authority
- BR
- Brazil
- Prior art keywords
- risk
- disease
- alzheimer
- methods
- prevention
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Pyrrole Compounds (AREA)
- Indole Compounds (AREA)
Abstract
"MéTODOS DE TRATAMENTO, PREVENçãO OU REDUçãODO RISCO DA DOENçA DE ALZHEIMER". São descritosmétodos de tratamento, prevenção ou redução do risco docomeço da doença de Alzheimer por administração de umaquantidade terapeuticamente efetiva de um inibidor da enzimaredutase 3-hidroxi-3-metilglutaril coenzima A ("inibidor da redutaseHMG CoA") ao paciente que está sob risco de evento coronarianoou cerebrovascular ou sob risco da doença de Alzheimer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/190,439 US6472421B1 (en) | 1998-11-13 | 1998-11-13 | Methods for treating, preventing, and reducing the risk of the onset of alzheimer's disease using an HMG CoA reductase inhibitor |
PCT/US1999/026979 WO2000028981A2 (en) | 1998-11-13 | 1999-11-15 | Methods for treating, preventing, and reducing the risk of the onset of alzheimer's disease using an hmg coa reductase inhibitor |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9915267A true BR9915267A (pt) | 2001-12-04 |
Family
ID=22701366
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9915267-3A BR9915267A (pt) | 1998-11-13 | 1999-11-15 | Métodos de tratamento, prevenção ou redução derisco de doença de alzheimer |
Country Status (9)
Country | Link |
---|---|
US (1) | US6472421B1 (pt) |
EP (1) | EP1131060A2 (pt) |
JP (1) | JP2002529500A (pt) |
AU (1) | AU771254B2 (pt) |
BR (1) | BR9915267A (pt) |
CA (1) | CA2350420A1 (pt) |
HK (1) | HK1040490A1 (pt) |
NO (1) | NO20012317L (pt) |
WO (1) | WO2000028981A2 (pt) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060141036A1 (en) * | 1997-12-12 | 2006-06-29 | Andrx Labs Llc | HMG-CoA reductase inhibitor extended release formulation |
US20020188012A1 (en) * | 1998-01-28 | 2002-12-12 | Bisgaier Charles Larry | Method for treating Alzheimer's disease |
NZ518822A (en) * | 1999-11-04 | 2004-12-24 | Andrx Corp | Treating a mammal with an APP processing disorder such as Alzheimer's Disease and Down's Syndrome by administering at least one HMG-CoA reductase inhibitor |
AUPQ846900A0 (en) * | 2000-06-29 | 2000-07-27 | Aruba International Pty Ltd | A vaccine |
US20090017069A1 (en) | 2000-06-29 | 2009-01-15 | Lipid Sciences, Inc. | SARS Vaccine Compositions and Methods of Making and Using Them |
WO2002062824A2 (en) * | 2001-02-05 | 2002-08-15 | Andrx Corporation | Method of treating amyloid ? precursor disorder |
US20020173535A1 (en) * | 2001-02-07 | 2002-11-21 | Renshaw Perry F. | Cholesterol-lowering agents as treatment for psychological and cognitive disorders |
AU2002252664A1 (en) * | 2001-04-13 | 2002-10-28 | First Genetic Trust | Methods and systems for managing informed consent processes |
US20030127386A1 (en) * | 2001-06-25 | 2003-07-10 | Bomberger David C. | Hollow fiber contactor systems for removal of lipids from fluids |
WO2003000372A2 (en) * | 2001-06-25 | 2003-01-03 | Lipid Sciences, Inc. | Systems and methods using multiple solvents for the removal of lipids from fluids |
US6991727B2 (en) * | 2001-06-25 | 2006-01-31 | Lipid Sciences, Inc. | Hollow fiber contactor systems for removal of lipids from fluids |
IL144900A (en) * | 2001-08-14 | 2013-12-31 | Neurim Pharma 1991 | Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs |
WO2003077896A1 (en) * | 2002-03-12 | 2003-09-25 | Merck & Co., Inc. | Drug combination therapy |
WO2003086379A1 (en) * | 2002-04-12 | 2003-10-23 | Henry Ford Health System | Treatment of neural injury and neurodegenerative disease with statins |
US8688385B2 (en) | 2003-02-20 | 2014-04-01 | Mayo Foundation For Medical Education And Research | Methods for selecting initial doses of psychotropic medications based on a CYP2D6 genotype |
US7393826B2 (en) | 2003-07-03 | 2008-07-01 | Lipid Sciences, Inc. | Methods and apparatus for creating particle derivatives of HDL with reduced lipid content |
DK2368565T3 (en) | 2003-07-03 | 2015-09-28 | Hdl Therapeutics Inc | Enrichment of pre-beta lipoproteins, high density |
JP2007515464A (ja) * | 2003-12-23 | 2007-06-14 | テムレル・リミテッド | 医薬組成物用ペレットの製造方法 |
US20070161700A1 (en) * | 2004-12-28 | 2007-07-12 | Kowa Company, Ltd. | Inhibitor for the formation of y-secretase complex |
KR20060135826A (ko) * | 2004-03-31 | 2006-12-29 | 코와 가부시키가이샤 | 외용제 |
CA2630604C (en) * | 2005-11-29 | 2016-01-19 | Children's Hospital Medical Center | Optimization and individualization of medication selection and dosing |
TWI432195B (zh) | 2007-10-03 | 2014-04-01 | Kowa Co | 神經細胞死亡抑制劑 |
ES2330184B1 (es) * | 2008-06-03 | 2010-07-05 | Neuron Biopharma, S.A. | Uso de estatinas como anticonvulsivantes, antiepilepticos y neuroprotectores. |
US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
US8877221B2 (en) | 2010-10-27 | 2014-11-04 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same |
WO2012170417A2 (en) | 2011-06-06 | 2012-12-13 | Warsaw Orthopedic, Inc. | Methods and compositions to enhance bone growth comprising a statin |
JP2021504003A (ja) | 2017-11-22 | 2021-02-15 | エイチディーエル セラピューティクス インコーポレイテッドHdl Therapeutics, Inc. | 血漿処理システムの流体回路をプライミングするシステムおよび方法 |
CA3087207A1 (en) | 2017-12-28 | 2019-07-04 | Hdl Therapeutics, Inc. | Methods for preserving and administering pre-beta high density lipoprotein extracted from human plasma |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4647576A (en) * | 1984-09-24 | 1987-03-03 | Warner-Lambert Company | Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis |
AU679675B2 (en) | 1992-05-11 | 1997-07-10 | Bayer Corporation | Methods for detecting beta amyloid precursor protein processing enzymes |
AU7397094A (en) | 1993-08-30 | 1995-03-22 | Merck & Co., Inc. | Prevention and treatment of alzheimer's disease |
US5965553A (en) * | 1996-06-20 | 1999-10-12 | Pfizer Inc. | Squalene synthetase inhibitors |
US6537987B1 (en) | 1996-06-20 | 2003-03-25 | Pfizer Inc. | 4,1-benzoxazepines or 4,1-benzothiazepines and their use as squalene synthetase inhibitors |
US5734054A (en) | 1996-11-05 | 1998-03-31 | Pharmacopeia, Inc. | Hydroxy-amino acid amides |
DE19716120A1 (de) | 1997-04-17 | 1998-10-22 | Europ Lab Molekularbiolog | Verwendung von cholesterinsenkenden Mitteln |
JP2002501887A (ja) | 1998-01-28 | 2002-01-22 | ワーナー−ランバート・カンパニー | アルツハイマー病の治療方法 |
US6080778A (en) * | 1998-03-23 | 2000-06-27 | Children's Medical Center Corporation | Methods for decreasing beta amyloid protein |
-
1998
- 1998-11-13 US US09/190,439 patent/US6472421B1/en not_active Expired - Lifetime
-
1999
- 1999-11-15 WO PCT/US1999/026979 patent/WO2000028981A2/en active IP Right Grant
- 1999-11-15 CA CA002350420A patent/CA2350420A1/en not_active Abandoned
- 1999-11-15 AU AU16241/00A patent/AU771254B2/en not_active Ceased
- 1999-11-15 EP EP99958976A patent/EP1131060A2/en not_active Withdrawn
- 1999-11-15 JP JP2000582029A patent/JP2002529500A/ja active Pending
- 1999-11-15 BR BR9915267-3A patent/BR9915267A/pt not_active Application Discontinuation
-
2001
- 2001-05-10 NO NO20012317A patent/NO20012317L/no not_active Application Discontinuation
-
2002
- 2002-03-12 HK HK02101917.6A patent/HK1040490A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
WO2000028981A3 (en) | 2000-11-09 |
WO2000028981A2 (en) | 2000-05-25 |
CA2350420A1 (en) | 2000-05-25 |
NO20012317D0 (no) | 2001-05-10 |
AU1624100A (en) | 2000-06-05 |
US6472421B1 (en) | 2002-10-29 |
NO20012317L (no) | 2001-07-06 |
EP1131060A2 (en) | 2001-09-12 |
JP2002529500A (ja) | 2002-09-10 |
HK1040490A1 (zh) | 2002-06-14 |
AU771254B2 (en) | 2004-03-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9915267A (pt) | Métodos de tratamento, prevenção ou redução derisco de doença de alzheimer | |
BR9915800A (pt) | Produto terapêutico para supressão dos ruìdos de ronco | |
AU2001257451A1 (en) | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism | |
DK0738512T3 (da) | Fremgangsmåde til forebyggelse af et andet hjerteanfald ved anvendelse af en HMG coenzsym A reduktasehæmmer | |
BR0312933A (pt) | Composição farmacêutica, unidade de dosagem farmacêutica, método para tratar uma ou mais doenças associadas com uma condição vascular, e, combinação terapêutica | |
HK1126957A1 (en) | Krill extracts for prevention and/or treatment of cardiovascular diseases | |
AU9125798A (en) | Specific saccharide compositions and methods for treating alzheimer's disease and other amyloidoses | |
BRPI0006634B8 (pt) | composição tópica compreendendo extrato de matricária no tratamento e prevenção de distúrbios inflamatórios | |
MX9207449A (es) | Inhibidores de la enzima proteolitica derivada de sacarina. | |
TNSN04167A1 (fr) | Derives de thiazole et d'oxazole qui modulent l'activite de ppar | |
BR0104830A (pt) | Tratamento de combinação para a demência ou déficits cognitivos associados com a doença de alzheimer e com a doença de parkinson | |
BR9913831A (pt) | Processo para tratamento de arteriosclerose empregando um inibidor de ap2 e combinação | |
PT97660A (pt) | Processo para a preparacao de composicoes farmaceuticas contendo um agente hipocolesterolizante e um inibidor da enzima de conversao da angiotensina | |
MX9606503A (es) | Inhibidores de pla2 y su uso para la inhibicion de la absorcion del colesterol interno. | |
HRP20050534A2 (en) | Prevention and treatment of alzheimer's disease | |
BR9813542A (pt) | Combinações de estatina-éter carboxialquìlico | |
BRPI0410654A (pt) | composto, composição farmacêutica, uso de um composto, método para tratar um distúrbio de um paciente, e, processo para a preparação de um composto | |
NO20000771D0 (no) | Anvendelse av fankinon for behandling av Alzheimers sykdom | |
HUP9801022A2 (hu) | Eljárás aldóz reduktáz inhibítor alkalmazása diabetikus szívizom-betegség megelőzésére vagy megfordítására | |
ATE180669T1 (de) | Verwendung von pregnanderivaten zur behandlung von tumoren | |
ID20165A (id) | Penggunaan asam 2-(3,4-dimetoksisinamoil)aminobenzoat untuk pembuatan obat untuk pengobatan atau pencegahan restenosis | |
HUP0004647A2 (hu) | Glükóz-amino-glükánok alkalmazása diabétesszel társult szembetegségek kezelésére szolgáló gyógyszerkészítmények előállítására | |
DE69730045D1 (de) | Behandlung der harninkontinenz und zusammenstellung dafür | |
BR0210426A (pt) | Metil análogo de sinvastatina para inibição de hmg-coa redutase e processo de obtenção do mesmo | |
EP1321146A3 (en) | Inhibitors of type 5 and 3 17beta-hydroxysteroid dehydrogenase and methods for their use |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |