HRP20050534A2 - Prevention and treatment of alzheimer's disease - Google Patents

Prevention and treatment of alzheimer's disease

Info

Publication number
HRP20050534A2
HRP20050534A2 HR20050534A HRP20050534A HRP20050534A2 HR P20050534 A2 HRP20050534 A2 HR P20050534A2 HR 20050534 A HR20050534 A HR 20050534A HR P20050534 A HRP20050534 A HR P20050534A HR P20050534 A2 HRP20050534 A2 HR P20050534A2
Authority
HR
Croatia
Prior art keywords
inhibitor
alzheimer
disease
prevention
treatment
Prior art date
Application number
HR20050534A
Other languages
Croatian (hr)
Inventor
Canton Thierry
Pradier Laurent
Benavides J�sus
Heuer Hubert
Schaefer Hans-Ludwig
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of HRP20050534A2 publication Critical patent/HRP20050534A2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)

Abstract

Prikazani izum se odnosi na primjenu inhibitora intestinalnog apsorpcije bilijarnih kiselina u prevenciji i liječenju Alzheimerove bolesti, po izboruu kombinaciji sa inhibitorom HMG-CoA reduktaze, inhibitorom apsorpcije kolesterola, inhibitorom sinteze kolesterola ili inhibitorom APP sekretaze.The present invention relates to the use of an inhibitor of intestinal biliary acid absorption in the prevention and treatment of Alzheimer's disease, optionally in combination with an HMG-CoA reductase inhibitor, a cholesterol absorption inhibitor, a cholesterol synthesis inhibitor or an APP secretase inhibitor.

HR20050534A 2002-12-12 2005-06-10 Prevention and treatment of alzheimer's disease HRP20050534A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0215722A FR2848452B1 (en) 2002-12-12 2002-12-12 APPLICATION OF INTESTINAL BILIARY ACID RECAPTURE INHIBITORS FOR THE PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE
PCT/FR2003/003654 WO2004062652A1 (en) 2002-12-12 2003-12-10 Prevention and treatment of alzheimer's disease

Publications (1)

Publication Number Publication Date
HRP20050534A2 true HRP20050534A2 (en) 2006-11-30

Family

ID=32338722

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20050534A HRP20050534A2 (en) 2002-12-12 2005-06-10 Prevention and treatment of alzheimer's disease

Country Status (22)

Country Link
EP (1) EP1572174A1 (en)
JP (1) JP2006514063A (en)
KR (1) KR20050084250A (en)
CN (1) CN1726016A (en)
AR (1) AR042354A1 (en)
AU (1) AU2003296802A1 (en)
BR (1) BR0317280A (en)
CA (1) CA2507945A1 (en)
CO (1) CO5700712A2 (en)
FR (1) FR2848452B1 (en)
HR (1) HRP20050534A2 (en)
MA (1) MA27500A1 (en)
MX (1) MXPA05005556A (en)
NO (1) NO20053341L (en)
NZ (1) NZ540496A (en)
PE (1) PE20040770A1 (en)
PL (1) PL377110A1 (en)
RS (1) RS20050420A (en)
RU (1) RU2005121909A (en)
TW (1) TW200503707A (en)
WO (1) WO2004062652A1 (en)
ZA (1) ZA200504656B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7521481B2 (en) 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
NZ546887A (en) 2003-11-03 2009-04-30 Probiodrug Ag Combinations useful for the treatment of neuronal disorders
AU2005210004B2 (en) 2004-02-05 2010-10-28 Probiodrug Ag Novel inhibitors of glutaminyl cyclase
EP1812007B1 (en) 2004-11-02 2011-09-07 Northwestern University Pyridazine compounds and methods
EP2015750A2 (en) 2006-04-28 2009-01-21 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
UA96633C2 (en) * 2007-05-22 2011-11-25 Оцука Фармасьютікал Ко., Лтд. Medicament comprising a carbostyril derivative and donepezil for treating alzheimer's disease
EA201891154A1 (en) 2011-10-28 2019-02-28 ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи INHIBITORS OF BILIC ACID RECYCLING IN THE TREATMENT OF CHOLESTATIC DISEASES OF THE LIVER IN CHILDREN
US20130108573A1 (en) * 2011-10-28 2013-05-02 Lumena Pharmaceuticals, Inc. Bile Acid Recycling Inhibitors for Treatment of Hypercholemia and Cholestatic Liver Disease

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2040996A1 (en) * 1990-05-02 1991-11-03 Robert L. Albright Composition and method for controlling cholesterol
AU668682B2 (en) * 1991-02-22 1996-05-16 Howard K. Shapiro Use of pharmaceutical compounds in the treatment of symptoms of disorders related to neurological diseases and etiologically related symptomology
US6491903B1 (en) * 1996-06-27 2002-12-10 Washington University Particles comprising amphiphilic copolymers
US5985936A (en) * 1997-12-18 1999-11-16 Forbes Medi-Tech, Inc. Method of preventing and delaying onset of Alzheimer's disease and composition therefor
DE69833971T2 (en) * 1998-01-28 2006-11-02 Warner-Lambert Co. Llc METHOD FOR THE TREATMENT OF ALZHEIMER'S DISEASE
US6080778A (en) * 1998-03-23 2000-06-27 Children's Medical Center Corporation Methods for decreasing beta amyloid protein
DE19825804C2 (en) * 1998-06-10 2000-08-24 Aventis Pharma Gmbh 1,4-Benzothiepin-1,1-dioxide derivatives, processes for their preparation and medicaments containing these compounds
US6221897B1 (en) * 1998-06-10 2001-04-24 Aventis Pharma Deutschland Gmbh Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
DE19845405C2 (en) * 1998-10-02 2000-07-13 Aventis Pharma Gmbh Aryl-substituted propanolamine derivatives and their use
US20010028895A1 (en) * 2000-02-04 2001-10-11 Bisgaier Charles L. Methods of treating alzheimer's disease
US20020028826A1 (en) * 2000-06-15 2002-03-07 Robl Jeffrey A. HMG-CoA reductase inhibitors and method
SE0104334D0 (en) * 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents
TWI329111B (en) * 2002-05-24 2010-08-21 X Ceptor Therapeutics Inc Azepinoindole and pyridoindole derivatives as pharmaceutical agents

Also Published As

Publication number Publication date
ZA200504656B (en) 2006-08-30
JP2006514063A (en) 2006-04-27
CN1726016A (en) 2006-01-25
EP1572174A1 (en) 2005-09-14
WO2004062652A1 (en) 2004-07-29
TW200503707A (en) 2005-02-01
NO20053341L (en) 2005-09-07
BR0317280A (en) 2005-11-08
NZ540496A (en) 2008-04-30
KR20050084250A (en) 2005-08-26
RS20050420A (en) 2007-04-10
RU2005121909A (en) 2006-01-20
MXPA05005556A (en) 2005-07-26
MA27500A1 (en) 2005-08-01
CO5700712A2 (en) 2006-11-30
AR042354A1 (en) 2005-06-15
FR2848452A1 (en) 2004-06-18
FR2848452B1 (en) 2007-04-06
NO20053341D0 (en) 2005-07-08
PE20040770A1 (en) 2004-12-10
CA2507945A1 (en) 2004-07-29
PL377110A1 (en) 2006-01-23
AU2003296802A1 (en) 2004-08-10

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