ES2143132T3 - Monohidratos de derivado de acido aminobenceno-sulfonico y su metodo de preparacion. - Google Patents

Monohidratos de derivado de acido aminobenceno-sulfonico y su metodo de preparacion.

Info

Publication number
ES2143132T3
ES2143132T3 ES96120136T ES96120136T ES2143132T3 ES 2143132 T3 ES2143132 T3 ES 2143132T3 ES 96120136 T ES96120136 T ES 96120136T ES 96120136 T ES96120136 T ES 96120136T ES 2143132 T3 ES2143132 T3 ES 2143132T3
Authority
ES
Spain
Prior art keywords
aminobenzen
monohydrates
preparation
acid derivative
sulphonic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96120136T
Other languages
English (en)
Inventor
Chika Yamazaki
Tadao Sato
Tatsuo Nagano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Chemical Corp
Original Assignee
Mitsubishi Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Chemical Corp filed Critical Mitsubishi Chemical Corp
Application granted granted Critical
Publication of ES2143132T3 publication Critical patent/ES2143132T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

UN MONOHIDRATO DE UN DERIVADO DE ACIDO AMINOBENCENOSULFONICO REPRESENTADO POR LA SIGUIENTE FORMULA (I), POR EJEMPLO, ACIDO 2(()1-PIPERAZINILO())-5-METILBENCENOSULFONICO, EL CUAL ESTA SUSTANCIALMENTE LIBRE DE CAMBIO DE PESO DEBIDO A LA ABSORCION DE HUMEDAD, Y PUEDE SER PESADO DE FORMA PRECISA EN UN PROCEDIMIENTO DE FABRICACION DE UNA COMPOSICION FARMACEUTICA PARA EL TRATAMIENTO DE ENFERMEDADES DEL CORAZON QUE COMPRENDE DICHO MONOHIDRATO.
ES96120136T 1995-12-15 1996-12-14 Monohidratos de derivado de acido aminobenceno-sulfonico y su metodo de preparacion. Expired - Lifetime ES2143132T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP32664895 1995-12-15
JP32706895 1995-12-15

Publications (1)

Publication Number Publication Date
ES2143132T3 true ES2143132T3 (es) 2000-05-01

Family

ID=26572248

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96120136T Expired - Lifetime ES2143132T3 (es) 1995-12-15 1996-12-14 Monohidratos de derivado de acido aminobenceno-sulfonico y su metodo de preparacion.

Country Status (9)

Country Link
US (2) US5990113A (es)
EP (1) EP0779283B1 (es)
AT (1) ATE190054T1 (es)
CA (1) CA2192731C (es)
DE (1) DE69606840T2 (es)
DK (1) DK0779283T3 (es)
ES (1) ES2143132T3 (es)
GR (1) GR3033231T3 (es)
PT (1) PT779283E (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2192731C (en) * 1995-12-15 2005-09-27 Chika Yamazaki Monohydrates of aminobenzenesulfonic acid derivatives and method for preparing thereof
CN1198617C (zh) * 1998-02-12 2005-04-27 三菱化学株式会社 治疗心脏舒张功能障碍的药物
US6562370B2 (en) 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of steroid drugs using hydroxide-releasing agents as permeation enhancers
US6565879B1 (en) 1999-12-16 2003-05-20 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers
US6673363B2 (en) * 1999-12-16 2004-01-06 Dermatrends, Inc. Transdermal and topical administration of local anesthetic agents using basic enhancers
US6645520B2 (en) * 1999-12-16 2003-11-11 Dermatrends, Inc. Transdermal administration of nonsteroidal anti-inflammatory drugs using hydroxide-releasing agents as permeation enhancers
US6562369B2 (en) 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of androgenic drugs hydroxide-releasing agents as permeation enhancers
US6562368B2 (en) * 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of oxybutynin using hydroxide-releasing agents as permeation enhancers
US6558695B2 (en) * 1999-12-16 2003-05-06 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers
US20030104041A1 (en) * 1999-12-16 2003-06-05 Tsung-Min Hsu Transdermal and topical administration of drugs using basic permeation enhancers
US6586000B2 (en) * 1999-12-16 2003-07-01 Dermatrends, Inc. Hydroxide-releasing agents as skin permeation enhancers
US6582724B2 (en) 1999-12-16 2003-06-24 Dermatrends, Inc. Dual enhancer composition for topical and transdermal drug delivery
KR100740477B1 (ko) * 1999-12-21 2007-07-19 미쯔비시 웰 파마 가부시키가이샤 신경계 장애의 치료 및/또는 예방약
JPWO2002034735A1 (ja) * 2000-10-23 2004-03-04 藤沢薬品工業株式会社 溶媒和物の取得方法及び溶媒和物
CA2440670A1 (en) * 2001-03-13 2002-09-19 Mitsubishi Pharma Corporation Agent for therapeutic and/or prophylactic treatment of diabetic ischemic heart disease
EP1409080A1 (en) * 2001-07-25 2004-04-21 Mitsubishi Pharma Corporation Medicament inhibiting sodium/calcium exchange system
JPWO2003011296A1 (ja) * 2001-07-30 2004-11-18 三菱ウェルファーマ株式会社 アミノベンゼンスルホン酸誘導体を活性成分とする医薬品製剤
JPWO2004019946A1 (ja) * 2002-08-30 2005-12-15 三菱ウェルファーマ株式会社 細胞内ナトリウムイオン過蓄積抑制薬
AU2003261968A1 (en) * 2002-09-06 2004-03-29 Mitsubishi Pharma Corporation Protective agents for transplanted organ
US7067867B2 (en) * 2002-09-30 2006-06-27 Nanosys, Inc. Large-area nonenabled macroelectronic substrates and uses therefor
US7491725B2 (en) 2004-02-06 2009-02-17 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
JPWO2005084668A1 (ja) * 2004-03-05 2007-11-29 三菱ウェルファーマ株式会社 虚血性循環器疾患の予防及び／又は治療のための薬剤
US7115971B2 (en) * 2004-03-23 2006-10-03 Nanosys, Inc. Nanowire varactor diode and methods of making same
AU2006252815A1 (en) * 2005-06-02 2006-12-07 Nanosys, Inc. Light emitting nanowires for macroelectronics
JPWO2008010566A1 (ja) * 2006-07-21 2009-12-17 田辺三菱製薬株式会社 ５−メチル‐２‐（ピペラジン−１−イル）ベンゼンスルホン酸の結晶多形
JPWO2008010567A1 (ja) 2006-07-21 2009-12-17 田辺三菱製薬株式会社 ５−メチル‐２‐（ピペラジン−１−イル）ベンゼンスルホン酸の塩形態又は溶媒和物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE390654C (de) 1922-03-19 1924-02-24 Paul Lucas Bunsenbrenner fuer fluessige Brennstoffe
GB1450746A (en) * 1974-01-31 1976-09-29 Ici Ltd Tripendioxazine dyestuffs
US4411904A (en) * 1981-05-29 1983-10-25 Warner-Lambert Company Diphenylpropanamines, compositions thereof and use thereof
GB2126598A (en) * 1982-08-16 1984-03-28 Ici Plc Reactive dyestuffs
US5053409A (en) * 1989-03-27 1991-10-01 Mitsubishi Kasei Corporation Aminobenzenesulfonic acid derivatives
JPH0686438B2 (ja) 1989-03-27 1994-11-02 三菱化成株式会社 アミノベンゼンスルホン酸誘導体
JP3083544B2 (ja) 1990-09-27 2000-09-04 三菱化学株式会社 心疾患を予防または治療する薬剤
JP2951476B2 (ja) 1992-03-27 1999-09-20 古河電気工業株式会社 水底布設長尺体の水中引入方法
US5486517A (en) * 1994-05-10 1996-01-23 Warner-Lambert Company Benzimidazoles and imidazopyridines as central nervous system agents
US5457107A (en) * 1994-09-16 1995-10-10 Merck & Co., Inc. Polymorphic form of a tachykinin receptor antagonist
CA2192731C (en) * 1995-12-15 2005-09-27 Chika Yamazaki Monohydrates of aminobenzenesulfonic acid derivatives and method for preparing thereof

Also Published As

Publication number Publication date
GR3033231T3 (en) 2000-08-31
EP0779283B1 (en) 2000-03-01
CA2192731C (en) 2005-09-27
DE69606840D1 (de) 2000-04-06
DE69606840T2 (de) 2000-10-12
US6245767B1 (en) 2001-06-12
CA2192731A1 (en) 1997-06-16
PT779283E (pt) 2000-08-31
ATE190054T1 (de) 2000-03-15
DK0779283T3 (da) 2000-06-26
EP0779283A1 (en) 1997-06-18
US5990113A (en) 1999-11-23

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