SK14762001A3 - Ligandy receptora estrogénu beta - Google Patents
Ligandy receptora estrogénu beta Download PDFInfo
- Publication number
- SK14762001A3 SK14762001A3 SK1476-2001A SK14762001A SK14762001A3 SK 14762001 A3 SK14762001 A3 SK 14762001A3 SK 14762001 A SK14762001 A SK 14762001A SK 14762001 A3 SK14762001 A3 SK 14762001A3
- Authority
- SK
- Slovakia
- Prior art keywords
- hydrogen
- disease
- hydroxyphenyl
- use according
- estrogen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12990199P | 1999-04-16 | 1999-04-16 | |
PCT/GB2000/001380 WO2000062765A2 (fr) | 1999-04-16 | 2000-04-11 | β-LIGANDS DE RECEPTEURS D'OESTROGENE |
Publications (1)
Publication Number | Publication Date |
---|---|
SK14762001A3 true SK14762001A3 (sk) | 2002-10-08 |
Family
ID=22442124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK1476-2001A SK14762001A3 (sk) | 1999-04-16 | 2000-04-11 | Ligandy receptora estrogénu beta |
Country Status (22)
Country | Link |
---|---|
US (1) | US6518301B1 (fr) |
EP (1) | EP1173164A2 (fr) |
JP (1) | JP2002542187A (fr) |
KR (1) | KR20010108509A (fr) |
CN (1) | CN1358091A (fr) |
AR (1) | AR043085A1 (fr) |
AU (1) | AU4128800A (fr) |
BG (1) | BG106103A (fr) |
BR (1) | BR0009814A (fr) |
CA (1) | CA2370126A1 (fr) |
CZ (1) | CZ20013714A3 (fr) |
EE (1) | EE200100526A (fr) |
HU (1) | HUP0200740A3 (fr) |
IL (1) | IL145839A0 (fr) |
IS (1) | IS6108A (fr) |
MX (1) | MXPA01010423A (fr) |
NO (1) | NO20015015L (fr) |
PL (1) | PL351314A1 (fr) |
SK (1) | SK14762001A3 (fr) |
TR (2) | TR200201762T2 (fr) |
WO (1) | WO2000062765A2 (fr) |
ZA (1) | ZA200108409B (fr) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPQ266199A0 (en) * | 1999-09-06 | 1999-09-30 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
US7226945B2 (en) | 2000-10-13 | 2007-06-05 | Astrazeneca Ab | Estrogen receptor-β ligands |
GB2361642A (en) * | 2000-10-24 | 2001-10-31 | Karobio Ab | Estrogen receptor beta (ERbeta) agonists for use in cancer treatment |
AU2002222853A1 (en) | 2000-12-07 | 2002-06-18 | Astrazeneca Ab | Therapeutic compounds |
AU2002221239A1 (en) * | 2000-12-07 | 2002-06-18 | Astrazeneca Ab | Therapeutic benzimidazole compounds |
US6559177B2 (en) | 2001-04-19 | 2003-05-06 | Wyeth | 5, 11-Dioxa-benzo[b]fluoren-10-one and 5-oxa-11-thia-benzo[b]fluoren-10-ones as estrogenic agents |
WO2003044006A1 (fr) | 2001-11-19 | 2003-05-30 | Eli Lilly And Company | Benzopyrans substitues convenant comme agonistes du recepteur aux oestrogenes beta |
UA83620C2 (ru) | 2001-12-05 | 2008-08-11 | Уайт | Замещенные бензоксазолы и их аналоги как эстрогенные агенты |
TWI306450B (en) | 2001-12-13 | 2009-02-21 | Wyeth Corp | Substituted phenyl naphthalenes as estrogenic agents |
TW200301107A (en) | 2001-12-13 | 2003-07-01 | Wyeth Corp | Substituted 6H-dibenzo[c,h]chromenes as estrogenic agents |
US6835745B2 (en) | 2002-01-15 | 2004-12-28 | Wyeth | Phenyl substituted thiophenes as estrogenic agents |
US7235539B2 (en) | 2002-01-23 | 2007-06-26 | Wyeth | 6-Hydroxyequilenins as estrogenic agents |
AU2003212856A1 (en) * | 2002-03-01 | 2003-09-16 | Eli Lilly And Company | Substituted benzopyrans as selective estrogen receptor-beta agonists |
US8668914B2 (en) | 2002-07-24 | 2014-03-11 | Brigham Young University | Use of equol for treating skin diseases |
AU2003259220C1 (en) | 2002-07-24 | 2017-08-24 | Australian Health & Nutrition Association Limited | Compositions and products containing enantiomeric equol, and methods for their making |
US7468445B2 (en) | 2002-08-07 | 2008-12-23 | University Of Mississippi | Antigiardial agents and use thereof |
US8580846B2 (en) | 2002-10-29 | 2013-11-12 | Brigham Young University | Use of equol for ameliorating or preventing neuropsychiatric and neurodegenerative diseases or disorders |
JP4889944B2 (ja) | 2002-10-29 | 2012-03-07 | コロラド ステート ユニバーシティー リサーチ ファウンデーション | アンドロゲンによって仲介される疾患を治療するためのエクオールの使用 |
US7674783B2 (en) * | 2002-11-22 | 2010-03-09 | Dimera Inc. | Estrogen beta receptor agonists to prevent or reduce the severity of cardiovascular disease |
WO2004094400A2 (fr) * | 2003-04-21 | 2004-11-04 | Eli Lilly And Company | Benzopyranes substitues en tant qu'agonistes selectifs du recepteur beta de l'oestrogene |
CA2564399A1 (fr) * | 2004-04-28 | 2005-11-17 | Brigham Young University | Utilisation de l'equol dans le traitement des maladies de la peau |
RU2007105232A (ru) * | 2004-08-26 | 2008-10-20 | Вайет (Us) | Пролекарственные замещенные бензоксазолы как эстрогенные агенты |
JP2008512458A (ja) | 2004-09-07 | 2008-04-24 | ワイス | 6H−[1]ベンゾピラノ[4,3−b]キノリン及びエストロゲン様物質としてのそれらの使用 |
KR20070086329A (ko) * | 2004-12-17 | 2007-08-27 | 와이어쓰 | 에스트로겐 베타 아고니스트의 신규 용도 |
EP1853578A1 (fr) * | 2005-02-15 | 2007-11-14 | Eli Lilly And Company | Tetralines substituees utilisees comme antagonistes selectifs du recepteur d'oestrogenes beta |
JP2008533177A (ja) * | 2005-03-24 | 2008-08-21 | ノボジェン リサーチ ピーティーワイ リミテッド | 抗炎症治療法 |
US8546451B2 (en) | 2005-11-28 | 2013-10-01 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
US8637706B2 (en) | 2005-11-28 | 2014-01-28 | Gtx, Inc. | Nuclear receptor binding agents |
US9409856B2 (en) | 2005-11-28 | 2016-08-09 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
US8158828B2 (en) * | 2005-11-28 | 2012-04-17 | Gtx, Inc. | Nuclear receptor binding agents |
EP1954670A4 (fr) * | 2005-11-28 | 2011-04-27 | Gtx Inc | Agents de liaison de recepteur nucleaire |
TWI366565B (en) | 2007-06-06 | 2012-06-21 | Otsuka Pharma Co Ltd | Quinolone compound and pharmaceutical composition |
WO2009026657A1 (fr) * | 2007-08-29 | 2009-03-05 | The University Of Sydney | Agonistes flavonoïdes de ppar |
JP5819196B2 (ja) * | 2008-10-29 | 2015-11-18 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | 液晶ディスプレイ |
TWI472525B (zh) | 2008-12-05 | 2015-02-11 | Otsuka Pharma Co Ltd | 喹啉酮化合物及藥學組成物 |
ES2343347B2 (es) * | 2009-01-27 | 2011-12-07 | Universidade De Santiago De Compostela | Uso de derivados de 3-fenilcumarinas 6-sustituidas y preparacion de nuevos derivados. |
US9427418B2 (en) | 2009-02-23 | 2016-08-30 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
US9624161B2 (en) | 2009-02-23 | 2017-04-18 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
CN101863867B (zh) * | 2009-04-14 | 2012-07-18 | 清华大学深圳研究生院 | 黄酮类化合物的衍生物及其制备方法与应用 |
US10292994B2 (en) | 2011-04-25 | 2019-05-21 | Council Of Scientific & Industrial Research | Bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders |
CN103450134B (zh) * | 2012-05-31 | 2017-12-22 | 中国医学科学院药物研究所 | 香豆素衍生物的制备及其在防治脑部重大疾病中的应用 |
US9718799B2 (en) * | 2015-05-11 | 2017-08-01 | University Of Kentucky Research Foundation | 3-aryl-4H-chromene-4-ones as antineoplastic agents for the treatment of cancer |
AU2019274580A1 (en) * | 2018-05-23 | 2020-12-03 | The Board Of Trustees Of The University Of Illinois | Estrogen receptor beta ligands for the prevention and treatment of multiple sclerosis (MS) and other demyelinating, inflammatory and neurodegenerative diseases |
EP3597187A1 (fr) * | 2018-07-16 | 2020-01-22 | Centre National De La Recherche Scientifique | Inhibiteurs de brag2 et applications associées |
CN112574177B (zh) * | 2020-12-21 | 2023-01-31 | 陕西师范大学 | 一类嘧啶衍生物及其制备抗肿瘤药物的应用 |
CN115322198A (zh) * | 2022-06-13 | 2022-11-11 | 上海工程技术大学 | 基于喹诺里西啶类衍生物的药物化合物及其制备方法和应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4954371A (fr) * | 1972-09-28 | 1974-05-27 | ||
GB1495189A (en) * | 1975-09-12 | 1977-12-14 | Pfizer Ltd | 4-oxo-4h-benzopyran derivatives and process for their preparation |
JPS6048924A (ja) * | 1983-08-24 | 1985-03-16 | Takeda Chem Ind Ltd | 骨粗鬆症治療剤 |
ZA873745B (en) * | 1986-06-04 | 1988-10-26 | Daiichi Seiyaku Co | Benzopyran derivatives |
JP3085464B2 (ja) * | 1990-05-24 | 2000-09-11 | コニカ株式会社 | 感熱拡散転写材料 |
US5204369A (en) * | 1991-07-01 | 1993-04-20 | The Endowment For Research In Human Biology | Method for the inhibition of aldh-i useful in the treatment of alcohol dependence or alcohol abuse |
JPH05112552A (ja) * | 1991-10-17 | 1993-05-07 | Tanabe Seiyaku Co Ltd | ベンゾピラン誘導体及びその製法 |
JP3166093B2 (ja) * | 1993-08-13 | 2001-05-14 | 森永乳業株式会社 | クマリン誘導体及びそれらの用途 |
JPH06321752A (ja) * | 1993-05-07 | 1994-11-22 | Kao Corp | 美白剤 |
JP3522754B2 (ja) * | 1993-12-16 | 2004-04-26 | マリンクロッド・インコーポレイテッド | 多価フェノール化合物類 |
US5998401A (en) | 1995-02-28 | 1999-12-07 | Eli Lilly And Company | Naphthyl compounds, intermediates, compositions, and methods |
JP3786447B2 (ja) * | 1995-03-31 | 2006-06-14 | エーザイ株式会社 | C型肝炎の予防・治療剤 |
AUPO203996A0 (en) * | 1996-08-30 | 1996-09-26 | Novogen Research Pty Ltd | Therapeutic uses |
US5916916A (en) * | 1996-10-10 | 1999-06-29 | Eli Lilly And Company | 1-aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods |
US5733926A (en) * | 1996-12-13 | 1998-03-31 | Gorbach; Sherwood L. | Isoflavonoids for treatment and prevention of alzheimer dementia and reduced cognitive functions |
GB9707013D0 (en) * | 1997-04-07 | 1997-05-28 | Univ Strathclyde | Halo and/or nitro-substituted flavonoids |
CA2287965C (fr) | 1997-05-01 | 2009-10-20 | Graham Edmund Kelly | Traitement ou prevention des symptomes menopausiques et de l'osteoporose |
-
2000
- 2000-04-11 IL IL14583900A patent/IL145839A0/xx unknown
- 2000-04-11 PL PL00351314A patent/PL351314A1/xx not_active Application Discontinuation
- 2000-04-11 BR BR0009814-0A patent/BR0009814A/pt not_active IP Right Cessation
- 2000-04-11 HU HU0200740A patent/HUP0200740A3/hu unknown
- 2000-04-11 TR TR2002/01762T patent/TR200201762T2/xx unknown
- 2000-04-11 EE EEP200100526A patent/EE200100526A/xx unknown
- 2000-04-11 CN CN00809003A patent/CN1358091A/zh active Pending
- 2000-04-11 CZ CZ20013714A patent/CZ20013714A3/cs unknown
- 2000-04-11 US US09/959,032 patent/US6518301B1/en not_active Expired - Fee Related
- 2000-04-11 KR KR1020017013143A patent/KR20010108509A/ko not_active Application Discontinuation
- 2000-04-11 SK SK1476-2001A patent/SK14762001A3/sk unknown
- 2000-04-11 WO PCT/GB2000/001380 patent/WO2000062765A2/fr not_active Application Discontinuation
- 2000-04-11 EP EP00920872A patent/EP1173164A2/fr not_active Withdrawn
- 2000-04-11 AU AU41288/00A patent/AU4128800A/en not_active Abandoned
- 2000-04-11 TR TR2001/02992T patent/TR200102992T2/xx unknown
- 2000-04-11 JP JP2000611902A patent/JP2002542187A/ja active Pending
- 2000-04-11 CA CA002370126A patent/CA2370126A1/fr not_active Abandoned
- 2000-04-11 MX MXPA01010423A patent/MXPA01010423A/es unknown
- 2000-04-14 AR ARP000101771A patent/AR043085A1/es unknown
-
2001
- 2001-10-12 ZA ZA200108409A patent/ZA200108409B/xx unknown
- 2001-10-15 NO NO20015015A patent/NO20015015L/no not_active Application Discontinuation
- 2001-10-15 IS IS6108A patent/IS6108A/is unknown
- 2001-11-13 BG BG106103A patent/BG106103A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EE200100526A (et) | 2002-12-16 |
HUP0200740A3 (en) | 2004-08-30 |
WO2000062765A2 (fr) | 2000-10-26 |
CZ20013714A3 (cs) | 2002-08-14 |
ZA200108409B (en) | 2003-03-26 |
IS6108A (is) | 2001-10-15 |
KR20010108509A (ko) | 2001-12-07 |
EP1173164A2 (fr) | 2002-01-23 |
TR200102992T2 (tr) | 2004-12-21 |
MXPA01010423A (es) | 2002-03-27 |
JP2002542187A (ja) | 2002-12-10 |
BR0009814A (pt) | 2002-01-08 |
AR043085A1 (es) | 2005-07-20 |
HUP0200740A2 (hu) | 2002-07-29 |
TR200201762T2 (tr) | 2002-10-21 |
WO2000062765A3 (fr) | 2001-09-07 |
CN1358091A (zh) | 2002-07-10 |
US6518301B1 (en) | 2003-02-11 |
PL351314A1 (en) | 2003-04-07 |
NO20015015D0 (no) | 2001-10-15 |
AU4128800A (en) | 2000-11-02 |
CA2370126A1 (fr) | 2000-10-26 |
NO20015015L (no) | 2001-12-17 |
IL145839A0 (en) | 2002-07-25 |
BG106103A (en) | 2002-05-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SK14762001A3 (sk) | Ligandy receptora estrogénu beta | |
RU2650118C2 (ru) | Способ лечения острого, хронического и подострого кашля и непреодолимого желания откашляться | |
KR100903713B1 (ko) | 바닐로이드 길항제로서 유용한 크로몬 유도체 | |
ES2795748T3 (es) | Derivados de 2-amino-bencimidazol como inhibidores de 5-lipoxigenasa y/o prostaglandina E sintasa para tratar enfermedades inflamatorias | |
JP2009536613A (ja) | Cb2受容体を調節する化合物 | |
JP2007509140A (ja) | 5−HT6受容体に関連する疾患の処置において有用な新規テトラヒドロスピロ{ピペリジン−2,7’−ピロロ[3,2−b]ピリジン誘導体および新規インドール誘導体 | |
JPH0372226B2 (fr) | ||
JP2008528634A (ja) | 腫瘍壊死因子インヒビター | |
CN104837843A (zh) | 作为gabaa受体调节剂的咪唑并哒嗪衍生物 | |
AU2006321349A1 (en) | Spirocyclic quinazoline derivatives as PDE7 inhibitors | |
JP2012184265A (ja) | イミダゾ[4,5−c]ピリジン化合物および抗ウイルス処置法 | |
US6903114B2 (en) | Derivatives of naphthalene with COMT inhibiting activity | |
JP2010527986A (ja) | スピロ環状キナゾリン誘導体およびpde7阻害剤としてのその使用 | |
EP0091795A1 (fr) | Benzimidazoles oléfiniques | |
US7226945B2 (en) | Estrogen receptor-β ligands | |
US7429607B2 (en) | 5-HT2B receptor antagonists | |
EP0092328B1 (fr) | Dérivés d'imidazoline | |
JP2005506324A (ja) | 抗炎症剤としてのアミノピロール化合物 | |
WO2002053550A1 (fr) | Derives de benzofurane et compositions pharmaceutiques contenant ces derniers | |
HRP20010180A2 (en) | N-substituted azabicycloheptane derivatives, production and use thereof | |
SK2842000A3 (en) | A COMBINATION OF A SELECTIVE 5-HT1A ANTAGONIST AND A SELECTIVEì (54) H5-HT1B ANTAGONIST OR PARTIAL AGONIST | |
ES2390560T3 (es) | Compuestos de 1,5-difenil-pirrolidin-2-ona como ligandos CB-1 | |
Oxford et al. | 5–HT2B receptor antagonists | |
CN115572293A (zh) | 用于gpr84拮抗剂的三环化合物 | |
KR20230074404A (ko) | 신규 플라보노이드 유도체 및 이를 유효성분으로 포함하는 대사성 질환의 예방 또는 치료용 약학 조성물 |