SK133997A3 - Derivatives of ascomycin, method for the preparation thereof and pharmaceutical composition containing the same - Google Patents

Derivatives of ascomycin, method for the preparation thereof and pharmaceutical composition containing the same Download PDF

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Publication number
SK133997A3
SK133997A3 SK1339-97A SK133997A SK133997A3 SK 133997 A3 SK133997 A3 SK 133997A3 SK 133997 A SK133997 A SK 133997A SK 133997 A3 SK133997 A3 SK 133997A3
Authority
SK
Slovakia
Prior art keywords
compound
group
compound according
groups
carboxy
Prior art date
Application number
SK1339-97A
Other languages
English (en)
Slovak (sk)
Inventor
Rene Hersperger
Reto Naef
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9507128.8A external-priority patent/GB9507128D0/en
Priority claimed from GBGB9526050.1A external-priority patent/GB9526050D0/en
Priority claimed from GBGB9526049.3A external-priority patent/GB9526049D0/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of SK133997A3 publication Critical patent/SK133997A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
SK1339-97A 1995-04-06 1996-04-04 Derivatives of ascomycin, method for the preparation thereof and pharmaceutical composition containing the same SK133997A3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9507128.8A GB9507128D0 (en) 1995-04-06 1995-04-06 Organic compounds
GBGB9526050.1A GB9526050D0 (en) 1995-12-20 1995-12-20 Organic compounds
GBGB9526049.3A GB9526049D0 (en) 1995-12-20 1995-12-20 Organic compounds
PCT/EP1996/001492 WO1996031514A1 (en) 1995-04-06 1996-04-04 Ascomycins

Publications (1)

Publication Number Publication Date
SK133997A3 true SK133997A3 (en) 1998-05-06

Family

ID=27267660

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1339-97A SK133997A3 (en) 1995-04-06 1996-04-04 Derivatives of ascomycin, method for the preparation thereof and pharmaceutical composition containing the same

Country Status (21)

Country Link
US (1) US5925649A (no)
EP (1) EP0819130A1 (no)
JP (1) JP2000505044A (no)
KR (1) KR19980703583A (no)
CN (1) CN1088068C (no)
AR (1) AR004480A1 (no)
AU (1) AU703523B2 (no)
BR (1) BR9604808A (no)
CA (1) CA2216562A1 (no)
CO (1) CO4750668A1 (no)
CZ (1) CZ312397A3 (no)
FI (1) FI973529A (no)
HU (1) HUP9801993A3 (no)
IL (1) IL117815A (no)
MX (1) MX9707636A (no)
NO (1) NO309273B1 (no)
NZ (1) NZ307170A (no)
PL (1) PL322553A1 (no)
SK (1) SK133997A3 (no)
TR (1) TR199700999T1 (no)
WO (1) WO1996031514A1 (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100505464B1 (ko) 1998-03-26 2005-08-04 후지사와 야꾸힝 고교 가부시키가이샤 서방성 제제
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
US6121257A (en) * 1999-03-31 2000-09-19 Abbott Laboratories Sulfamate containing macrocyclic immunomodulators
ES2232439T3 (es) * 1999-04-30 2005-06-01 Sucampo Ag Uso de compuestos macrolidos para el tratamiento de los ojos secos.
US7063857B1 (en) 1999-04-30 2006-06-20 Sucampo Ag Use of macrolide compounds for the treatment of dry eye
MXPA02001857A (es) 1999-08-24 2003-07-14 Cellgate Inc Composiciones y metodos para incrementar la entrega de drogas a traves y dentro de tejidos epiteliales.
AR033151A1 (es) * 2001-04-12 2003-12-03 Sucampo Pharmaceuticals Inc Agente para el tratamiento oftalmico topico de las enfermedades inflamatorias oculares
WO2002089796A2 (en) * 2001-05-09 2002-11-14 Novartis Ag Methods for selective immunomodulation using pimecrolimus
NZ539850A (en) * 2002-11-15 2008-05-30 Novartis Ag Drug delivery device or system comprising pimecromilus
AU2004212264B9 (en) * 2003-02-17 2009-11-26 Cipla Limited Pharmaceutical patch
TWI324604B (en) 2003-06-18 2010-05-11 Novartis Ag New use of staurosporine derivatives
US7780973B2 (en) * 2003-12-15 2010-08-24 Ethicon Endo-Surgery, Inc. Method and device for minimally invasive implantation of biomaterial
US20050142161A1 (en) * 2003-12-30 2005-06-30 Freeman Lynetta J. Collagen matrix for soft tissue augmentation
WO2005063242A1 (en) * 2003-12-30 2005-07-14 Astellas Pharma Inc. Use of macrolides for treating or preventing airflow obstruction
WO2006082588A2 (en) * 2005-02-07 2006-08-10 Pharmalight Inc. Method and device for ophthalmic administration of active pharmaceutical ingredients
JPWO2016068208A1 (ja) 2014-10-28 2017-08-10 晃史 山口 妊娠状態を改善するための薬剤及びその利用
CN112533599A (zh) 2018-08-10 2021-03-19 山口晃史 与母体和胎儿的关系中的体液免疫相关的疾病的治疗药
US20220062245A1 (en) 2018-12-18 2022-03-03 Koushi Yamaguchi Agent for improving infertility, recurrent miscarriage, and state of pregnancy

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3244592A (en) * 1962-06-09 1966-04-05 Arai Tadashi Ascomycin and process for its production
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
JPS6317884A (ja) * 1986-05-30 1988-01-25 Fujisawa Pharmaceut Co Ltd トリシクロ化合物
JPH01125394A (ja) * 1987-11-10 1989-05-17 Mect Corp シアロシルグリセロリピッド類及びその製造方法
AU630866B2 (en) * 1987-12-09 1992-11-12 Fisons Plc Macrocyclic compounds
WO1991002736A1 (en) * 1989-08-18 1991-03-07 Fisons Plc Macrocyclic compounds
KR0159766B1 (ko) * 1989-10-16 1998-12-01 후지사와 토모키치로 양모제 조성물
EP0427680B1 (en) * 1989-11-09 1995-08-23 Sandoz Ltd. Heteroatoms-containing tricyclic compounds
WO1991013899A1 (en) * 1990-03-12 1991-09-19 Fujisawa Pharmaceutical Co., Ltd. Tricyclo compounds
WO1991019495A1 (en) * 1990-06-11 1991-12-26 Fujisawa Pharmaceutical Co., Ltd. Use of a macrolide compound such as fk 506 for manufacturing a medicament for treating idiopathic thrombocytopenic purpura and basedow's disease
MY110418A (en) * 1990-07-02 1998-05-30 Novartis Ag Heteroatoms-containing tricyclic compounds.
SG46547A1 (en) * 1990-09-04 1998-02-20 Fujisawa Pharmaceutical Co Ointments containing tricyclic compounds
IE65341B1 (en) * 1990-11-08 1995-10-18 Fujisawa Pharmaceutical Co Suspensions containing tricyclic compounds
US5208241A (en) * 1991-09-09 1993-05-04 Merck & Co., Inc. N-heteroaryl, n-alkylheteroaryl, n-alkenylheteroaryl and n-alkynylheteroarylmacrolides having immunosuppressive activity
US5252732A (en) * 1991-09-09 1993-10-12 Merck & Co., Inc. D-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl and O-alkynylheteroarylmacrolides having immunosuppressive activity
US5247076A (en) * 1991-09-09 1993-09-21 Merck & Co., Inc. Imidazolidyl macrolides having immunosuppressive activity
US5457194A (en) * 1993-03-17 1995-10-10 Abbott Laboratories Substituted aliphatic amine-containing macrocyclic immunomodulators
NZ295170A (en) * 1994-10-26 1999-02-25 Novartis Ag Topical pharmaceutical compositions comprising a fk506 class compound, an unsaturated fatty alcohol, water and diether alcohol, alkanediol or ether diol as a solvent

Also Published As

Publication number Publication date
FI973529A (fi) 1997-11-25
PL322553A1 (en) 1998-02-02
NO974536D0 (no) 1997-10-01
CN1180359A (zh) 1998-04-29
NO309273B1 (no) 2001-01-08
NO974536L (no) 1997-10-01
EP0819130A1 (en) 1998-01-21
FI973529A0 (fi) 1997-08-27
MX9707636A (es) 1998-06-30
HUP9801993A3 (en) 2000-04-28
BR9604808A (pt) 1998-06-09
HUP9801993A2 (hu) 1998-12-28
AU703523B2 (en) 1999-03-25
AU5645396A (en) 1996-10-23
CO4750668A1 (es) 1999-03-31
IL117815A (en) 2000-07-16
TR199700999T1 (xx) 1998-01-21
CA2216562A1 (en) 1996-10-10
CZ312397A3 (cs) 1998-01-14
JP2000505044A (ja) 2000-04-25
NZ307170A (en) 1999-03-29
AR004480A1 (es) 1998-12-16
KR19980703583A (ko) 1998-11-05
IL117815A0 (en) 1996-08-04
US5925649A (en) 1999-07-20
CN1088068C (zh) 2002-07-24
WO1996031514A1 (en) 1996-10-10

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