SK13142003A3 - Core-glycosylated HCV envelope proteins - Google Patents

Core-glycosylated HCV envelope proteins Download PDF

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Publication number
SK13142003A3
SK13142003A3 SK1314-2003A SK13142003A SK13142003A3 SK 13142003 A3 SK13142003 A3 SK 13142003A3 SK 13142003 A SK13142003 A SK 13142003A SK 13142003 A3 SK13142003 A3 SK 13142003A3
Authority
SK
Slovakia
Prior art keywords
hcv
protein
coat protein
proteins
seq
Prior art date
Application number
SK1314-2003A
Other languages
English (en)
Slovak (sk)
Inventor
Erik Depla
Alfons Bosman
Geert Deschamps
Erwin Sablon
Manfred Suckow
Isabelle Samson
Gert Verheyden
Original Assignee
Innogenetics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innogenetics Nv filed Critical Innogenetics Nv
Publication of SK13142003A3 publication Critical patent/SK13142003A3/sk

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/18Togaviridae; Flaviviridae
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24223Virus like particles [VLP]

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SK1314-2003A 2001-04-24 2002-04-24 Core-glycosylated HCV envelope proteins SK13142003A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01870088 2001-04-24
US30560401P 2001-07-17 2001-07-17
PCT/BE2002/000064 WO2002086101A2 (en) 2001-04-24 2002-04-24 Core-glycosylated hcv envelope proteins

Publications (1)

Publication Number Publication Date
SK13142003A3 true SK13142003A3 (en) 2004-11-03

Family

ID=34072546

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1314-2003A SK13142003A3 (en) 2001-04-24 2002-04-24 Core-glycosylated HCV envelope proteins

Country Status (20)

Country Link
US (3) US7048930B2 (de)
EP (3) EP1417298A2 (de)
JP (2) JP4261195B2 (de)
KR (1) KR100950104B1 (de)
CN (1) CN1636050A (de)
AR (3) AR035867A1 (de)
AU (3) AU2002252856A1 (de)
BR (2) BR0209033A (de)
CA (3) CA2443740A1 (de)
CZ (1) CZ20032853A3 (de)
HU (1) HUP0303924A2 (de)
MX (2) MXPA03009626A (de)
NZ (2) NZ529324A (de)
OA (1) OA13092A (de)
PL (1) PL366621A1 (de)
RU (1) RU2274643C2 (de)
SK (1) SK13142003A3 (de)
WO (3) WO2002086101A2 (de)
YU (1) YU84103A (de)
ZA (3) ZA200308274B (de)

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EP1417298A2 (de) * 2001-04-24 2004-05-12 Innogenetics N.V. Core-glykosylierte hcv hüllproteine
DE10143490C2 (de) * 2001-09-05 2003-12-11 Gsf Forschungszentrum Umwelt Rekombinantes MVA mit der Fähigkeit zur Expression von HCV Struktur-Antigenen
JP2006516955A (ja) * 2002-11-08 2006-07-13 イノジェネティックス・ナムローゼ・フェンノートシャップ E1ペプチド及びns3ペプチドを含むhcvワクチン組成物
US7439042B2 (en) * 2002-12-16 2008-10-21 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis C infection
JP4371739B2 (ja) * 2003-09-02 2009-11-25 株式会社東芝 シリアルataインタフェースを持つ電子機器及びシリアルataバスのパワーセーブ方法
EP1574517A1 (de) * 2004-03-09 2005-09-14 Innogenetics N.V. HCV E1 beinhaltend spezifische Disulfidbrücken
EP1602664A1 (de) * 2004-03-08 2005-12-07 Innogenetics N.V. HCV E1 beinhaltend spezifische Disulfidbrücken
JP4885476B2 (ja) * 2004-05-21 2012-02-29 株式会社日本触媒 タンパク質及び/又はペプチドの細胞内導入方法
AU2011254055B2 (en) * 2004-10-18 2012-12-20 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis C infection
AU2005295317B2 (en) * 2004-10-18 2011-10-13 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis C infection
US20060234360A1 (en) * 2005-04-13 2006-10-19 Paola Branduardi Ascorbic acid production from D-glucose in yeast
US9216212B2 (en) 2005-08-05 2015-12-22 University Of Massachusetts Virus-like particles as vaccines for paramyxovirus
US7951384B2 (en) * 2005-08-05 2011-05-31 University Of Massachusetts Virus-like particles as vaccines for paramyxovirus
AR058140A1 (es) * 2005-10-24 2008-01-23 Wyeth Corp Metodo de produccion proteica utilizando compuestos anti-senescencia
EP2027271A4 (de) * 2006-05-19 2010-06-09 Glycofi Inc Rekombinante vektoren
AU2015234338C1 (en) * 2006-07-28 2017-07-20 The Trustees Of The University Of Pennsylvania Improved vaccines and methods for using the same
AU2007288129B2 (en) * 2006-08-25 2013-03-07 The Macfarlane Burnet Institute For Medical Research And Public Health Limited Recombinant HCV E2 glycoprotein
US8728489B2 (en) 2008-09-19 2014-05-20 Globeimmune, Inc. Immunotherapy for chronic hepatitis C virus infection
US8580270B2 (en) 2008-09-30 2013-11-12 University Of Massachusetts Respiratory synctial virus (RSV) sequences for protein expression and vaccines
US20100104555A1 (en) * 2008-10-24 2010-04-29 The Scripps Research Institute HCV neutralizing epitopes
DE102009044224A1 (de) * 2009-10-09 2011-04-28 PomBio Tech GmbH Starterzentrum der Universität des Saarlandes Campus Geb. A1-1 Methode zur Produktion von HCV Virus-ähnlichen Partikeln
MX345854B (es) 2010-12-22 2017-02-17 Bayer Ip Gmbh Respuesta inmune potenciada en la especie bovina.
US20140155469A1 (en) 2011-04-19 2014-06-05 The Research Foundation Of State University Of New York Adeno-associated-virus rep sequences, vectors and viruses
EP3590950A1 (de) 2011-05-09 2020-01-08 Ablynx NV Verfahren zur herstellung von einzelvariablen immunglobulindomänen
CA2940794C (en) 2014-02-28 2022-05-31 Bayer Animal Health Gmbh Immunostimulatory plasmids
WO2017081520A1 (en) * 2015-11-13 2017-05-18 Mammedov Tarlan Production of in vivo n-deglycosylated recombinant proteins by co-expression with endo h
EP3184642B1 (de) * 2015-12-22 2019-05-08 bisy e.U. Hefezelle
EP3515483A4 (de) 2016-09-21 2020-12-16 The Governors of the University of Alberta Immunogene zusammensetzungen des hepatitis-c-virus und verfahren zur verwendung davon

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Also Published As

Publication number Publication date
OA13092A (en) 2006-11-10
AU2002308449B2 (en) 2008-05-29
EP1381671A2 (de) 2004-01-21
ZA200308274B (en) 2005-01-24
CN1636050A (zh) 2005-07-06
US20030211597A1 (en) 2003-11-13
BR0209033A (pt) 2005-01-11
EP1417298A2 (de) 2004-05-12
KR100950104B1 (ko) 2010-03-30
AU2002257392B2 (en) 2007-05-10
AR035869A1 (es) 2004-07-21
CZ20032853A3 (cs) 2004-08-18
ZA200308277B (en) 2004-07-08
AU2002252856A1 (en) 2002-11-05
CA2443740A1 (en) 2002-10-31
WO2002086101A3 (en) 2004-02-19
JP2004532029A (ja) 2004-10-21
AR035868A1 (es) 2004-07-21
WO2002086100A3 (en) 2004-02-19
US20030152940A1 (en) 2003-08-14
US7314925B2 (en) 2008-01-01
MXPA03009626A (es) 2004-06-30
PL366621A1 (en) 2005-02-07
CA2444006A1 (en) 2002-10-31
ZA200308272B (en) 2005-01-24
WO2002085932A3 (en) 2003-03-13
BR0209034A (pt) 2005-02-01
KR20030094359A (ko) 2003-12-11
CA2443781A1 (en) 2002-10-31
NZ529019A (en) 2004-05-28
NZ529324A (en) 2005-08-26
US7048930B2 (en) 2006-05-23
MXPA03009632A (es) 2004-06-30
JP4261195B2 (ja) 2009-04-30
WO2002085932A2 (en) 2002-10-31
JP2004536052A (ja) 2004-12-02
WO2002086101A2 (en) 2002-10-31
RU2274643C2 (ru) 2006-04-20
HUP0303924A2 (hu) 2004-03-01
EP1414942A2 (de) 2004-05-06
YU84103A (sh) 2006-05-25
AR035867A1 (es) 2004-07-21
JP4173741B2 (ja) 2008-10-29
US7238356B2 (en) 2007-07-03
US20030108561A1 (en) 2003-06-12
WO2002086100A2 (en) 2002-10-31
RU2003130955A (ru) 2005-04-20

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SABLON et al. Patent 2443740 Summary

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