SI9111227B - Farmacevtski preprat z aktivno materijo Flupirtin za zdravljenje bolezni, ki se nanašajo na napetost mišic - Google Patents
Farmacevtski preprat z aktivno materijo Flupirtin za zdravljenje bolezni, ki se nanašajo na napetost mišic Download PDFInfo
- Publication number
- SI9111227B SI9111227B SI9111227A SI9111227A SI9111227B SI 9111227 B SI9111227 B SI 9111227B SI 9111227 A SI9111227 A SI 9111227A SI 9111227 A SI9111227 A SI 9111227A SI 9111227 B SI9111227 B SI 9111227B
- Authority
- SI
- Slovenia
- Prior art keywords
- flupirtine
- pharmaceutical composition
- muscle tension
- active agent
- disease
- Prior art date
Links
- JUUFBMODXQKSTD-UHFFFAOYSA-N N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester Chemical compound N1=C(N)C(NC(=O)OCC)=CC=C1NCC1=CC=C(F)C=C1 JUUFBMODXQKSTD-UHFFFAOYSA-N 0.000 title claims abstract 5
- 229960003667 flupirtine Drugs 0.000 title claims abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 title claims 3
- 206010049816 Muscle tightness Diseases 0.000 title claims 2
- 239000013543 active substance Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract 3
- 208000018737 Parkinson disease Diseases 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 2
- DNXIKVLOVZVMQF-UHFFFAOYSA-N (3beta,16beta,17alpha,18beta,20alpha)-17-hydroxy-11-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(C(=O)OC)C(O)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 DNXIKVLOVZVMQF-UHFFFAOYSA-N 0.000 claims 1
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 claims 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 claims 1
- LCQMZZCPPSWADO-UHFFFAOYSA-N Reserpilin Natural products COC(=O)C1COCC2CN3CCc4c([nH]c5cc(OC)c(OC)cc45)C3CC12 LCQMZZCPPSWADO-UHFFFAOYSA-N 0.000 claims 1
- QEVHRUUCFGRFIF-SFWBKIHZSA-N Reserpine Natural products O=C(OC)[C@@H]1[C@H](OC)[C@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)C[C@H]2[C@@H]1C[C@H]1N(C2)CCc2c3c([nH]c12)cc(OC)cc3 QEVHRUUCFGRFIF-SFWBKIHZSA-N 0.000 claims 1
- YSXKPIUOCJLQIE-UHFFFAOYSA-N biperiden Chemical compound C1C(C=C2)CC2C1C(C=1C=CC=CC=1)(O)CCN1CCCCC1 YSXKPIUOCJLQIE-UHFFFAOYSA-N 0.000 claims 1
- 229960003003 biperiden Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- BJOIZNZVOZKDIG-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C([C]5C=CC(OC)=CC5=N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 BJOIZNZVOZKDIG-MDEJGZGSSA-N 0.000 claims 1
- 229960003147 reserpine Drugs 0.000 claims 1
- MDMGHDFNKNZPAU-UHFFFAOYSA-N roserpine Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(OC(C)=O)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 MDMGHDFNKNZPAU-UHFFFAOYSA-N 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- MEZLKOACVSPNER-GFCCVEGCSA-N selegiline Chemical group C#CCN(C)[C@H](C)CC1=CC=CC=C1 MEZLKOACVSPNER-GFCCVEGCSA-N 0.000 claims 1
- 229960003946 selegiline Drugs 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 206010052904 Musculoskeletal stiffness Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyrrole Compounds (AREA)
- Golf Clubs (AREA)
- Details Of Television Scanning (AREA)
- Paints Or Removers (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4022442 | 1990-07-14 | ||
| IN421CA1991 IN172468B (cs) | 1990-07-14 | 1991-06-04 | |
| YU122791A YU48054B (sh) | 1990-07-14 | 1991-07-12 | Postupak za proizvodnju farmaceutskog preparata |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SI9111227A SI9111227A (en) | 1995-06-30 |
| SI9111227B true SI9111227B (sl) | 2000-12-31 |
Family
ID=25895002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9111227A SI9111227B (sl) | 1990-07-14 | 1991-07-12 | Farmacevtski preprat z aktivno materijo Flupirtin za zdravljenje bolezni, ki se nanašajo na napetost mišic |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US5162346A (cs) |
| EP (2) | EP0659410B1 (cs) |
| KR (1) | KR0182811B1 (cs) |
| CN (1) | CN1070700C (cs) |
| AT (2) | ATE206919T1 (cs) |
| AU (1) | AU634073B2 (cs) |
| CA (1) | CA2046943C (cs) |
| CZ (1) | CZ280879B6 (cs) |
| DE (3) | DE59107331D1 (cs) |
| DK (2) | DK0467164T3 (cs) |
| EG (1) | EG19814A (cs) |
| ES (2) | ES2164111T3 (cs) |
| GR (1) | GR3019179T3 (cs) |
| HR (1) | HRP920667B1 (cs) |
| HU (1) | HU206973B (cs) |
| IE (1) | IE74688B1 (cs) |
| IL (1) | IL98810A (cs) |
| IN (1) | IN172468B (cs) |
| LT (1) | LT3593B (cs) |
| LV (1) | LV10048B (cs) |
| MC (1) | MC2272A1 (cs) |
| MX (1) | MX9100160A (cs) |
| NO (1) | NO912758L (cs) |
| NZ (1) | NZ238940A (cs) |
| PT (1) | PT98291B (cs) |
| RO (1) | RO108220B1 (cs) |
| RU (1) | RU2070408C1 (cs) |
| SI (1) | SI9111227B (cs) |
| SK (1) | SK279567B6 (cs) |
| ZA (1) | ZA915466B (cs) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE59307753D1 (de) * | 1992-03-11 | 1998-01-15 | Asta Medica Ag | Tabletten, Granulate und Pellets mit hohem Gehalt an Wirkstoffen für hochkonzentrierte, feste Darreichungsformen |
| DE4319649A1 (de) * | 1993-03-18 | 1994-09-22 | Asta Medica Ag | Feste Flupirtin enthaltende orale Darreichungsformen mit kontrollierter Wirkstoffabgabe |
| DE4327516A1 (de) * | 1993-08-17 | 1995-02-23 | Asta Medica Ag | Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin |
| GB9426079D0 (en) * | 1994-12-23 | 1995-02-22 | Orion Yhtymae Oy | A gelatine capsule |
| DE19541405A1 (de) * | 1995-11-07 | 1997-05-15 | Asta Medica Ag | Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen, die mit einer Beeinträchtigung des hämatopoetischen Zellsystems einhergehen |
| US6284794B1 (en) | 1996-11-05 | 2001-09-04 | Head Explorer Aps | Method for treating tension-type headache with inhibitors of nitric oxide and nitric oxide synthase |
| US6610324B2 (en) * | 1999-04-07 | 2003-08-26 | The Mclean Hospital Corporation | Flupirtine in the treatment of fibromyalgia and related conditions |
| EP1242078A2 (de) * | 1999-08-03 | 2002-09-25 | AWD.pharma GmbH & Co.KG | Verwendung von flupirtin zur linderung von schmerzen bei degenerativen gelenkerkrankungen von hunden und katzen |
| US6821995B1 (en) | 1999-12-01 | 2004-11-23 | Duke University | Method of treating batten disease |
| US20040122090A1 (en) * | 2001-12-07 | 2004-06-24 | Lipton Stuart A. | Methods for treating neuropsychiatric disorders with nmda receptor antagonists |
| RU2213565C1 (ru) * | 2002-06-24 | 2003-10-10 | Общество с ограниченной ответственностью "Паркинфарм" | Способ лечебного воздействия на организм пациента при лечении болезни паркинсона |
| DE10255415A1 (de) * | 2002-11-28 | 2004-06-09 | Bayer Healthcare Ag | Dermale Applikation von Flupirtin |
| DE10327674A1 (de) | 2003-06-20 | 2005-01-05 | Awd.Pharma Gmbh & Co. Kg | Injizierbare Darreichungsform von Flupirtin |
| US7799832B2 (en) | 2003-10-23 | 2010-09-21 | Valeant Pharmaceuticals North America | Combinations of retigabine and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains |
| DE102004001558A1 (de) * | 2004-01-10 | 2005-08-18 | Bayer Healthcare Ag | Arzneimittel zur topischen Applikation bei Tieren |
| US20050196461A1 (en) * | 2004-01-14 | 2005-09-08 | Udell Ronald G. | Ceramide formulations suitable for oral administration |
| WO2005072705A1 (en) * | 2004-01-29 | 2005-08-11 | Neuromolecular, Inc. | Combination of a nmda receptor antagonist and a mao-inhibitor or a gadpf-inhibitor for the treatment of central nervous system-related conditions |
| US20050220862A1 (en) * | 2004-03-31 | 2005-10-06 | Bernstein Joel E | Compositions with reduced hepatotoxicity |
| US7619007B2 (en) * | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
| EP1688141A1 (en) * | 2005-01-31 | 2006-08-09 | elbion AG | The use of flupirtine for the treatment of overactive bladder and associated diseases, and for the treatment of irritable bowel syndrome |
| DK1874282T3 (da) | 2005-04-06 | 2010-10-25 | Adamas Pharmaceuticals Inc | Fremgangsmåder og præparater til behandling af CNS lidelser |
| EP2012769A1 (en) * | 2006-05-02 | 2009-01-14 | Rundfeldt, Chris | Potassium channel activators for the prevention and treatment of dystonia and dystonia-like symptoms |
| US7960436B2 (en) | 2006-06-05 | 2011-06-14 | Valeant Pharmaceuticals International | Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators |
| NZ575652A (en) * | 2006-08-23 | 2011-08-26 | Valeant Pharmaceuticals Int | Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators |
| US8993593B2 (en) * | 2006-08-23 | 2015-03-31 | Valeant Pharmaceuticals International | N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators |
| US8722929B2 (en) * | 2006-10-10 | 2014-05-13 | Valeant Pharmaceuticals International | N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators |
| JP2010511052A (ja) * | 2006-11-28 | 2010-04-08 | バレアント ファーマシューティカルズ インターナショナル | カリウムチャネル調節因子としての１，４ジアミノ二環式レチガビンアナログ |
| US20080279930A1 (en) * | 2007-05-07 | 2008-11-13 | Bernd Terhaag | Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof |
| US8367684B2 (en) * | 2007-06-13 | 2013-02-05 | Valeant Pharmaceuticals International | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
| EA201070189A1 (ru) * | 2007-08-01 | 2010-08-30 | Х. Лундбекк А/С | Применение соединений, открывающих калиевые каналы kcnq, для подавления симптомов или лечения расстройств или состояний, при которых нарушается дофаминергическая система |
| US8563566B2 (en) * | 2007-08-01 | 2013-10-22 | Valeant Pharmaceuticals International | Naphthyridine derivatives as potassium channel modulators |
| US7786146B2 (en) * | 2007-08-13 | 2010-08-31 | Valeant Pharmaceuticals International | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators |
| ES2347119B2 (es) * | 2009-04-22 | 2011-04-28 | Universidad De Santiago De Compostela | Nanocapsulas de poliarginina. |
| DE102010030053A1 (de) | 2010-06-14 | 2011-12-15 | Awd.Pharma Gmbh & Co.Kg | Injizierbare Darreichungsform von Flupirtin |
| JP6251667B2 (ja) * | 2014-06-03 | 2017-12-20 | アサヒカルピスウェルネス株式会社 | 錠剤型即放性製剤及びその製造方法 |
| DE102017007385A1 (de) | 2017-08-02 | 2019-02-07 | Christoph Hoock | Maleatfreie feste Arzneimittelformen |
| KR20220080119A (ko) | 2019-10-10 | 2022-06-14 | 제논 파마슈티칼스 인크. | 선택적 칼륨 채널 조절제의 고체 상태 결정성 형태 |
| CR20220250A (es) | 2019-11-08 | 2022-08-19 | Xenon Pharmaceuticals Inc | Métodos para el tratamiento de trastornos depresivos |
| IL304920A (en) | 2021-02-09 | 2023-10-01 | Xenon Pharmaceuticals Inc | Voltage-gated potassium channel opener for use in treating anhedonia |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1795858C2 (de) | 1968-07-19 | 1979-01-11 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt | Benzylaminopyridine |
| DE3133519A1 (de) | 1980-09-13 | 1982-06-09 | Degussa Ag, 6000 Frankfurt | "2-amino-3-carbethoxyamino-6-(p-fluor-benzylamino)-pyridin-maleat" |
| EP0189788B1 (de) * | 1985-01-23 | 1989-09-13 | ASTA Pharma Aktiengesellschaft | Synergistische Kombination von Flupirtin und nicht-steroidalen Antiphlogistika |
| DE3663775D1 (en) * | 1985-02-23 | 1989-07-13 | Asta Pharma Ag | Combination of flupirtin with spasmolytics having an anticholinergic effect |
| DE3604575A1 (de) | 1985-02-23 | 1986-08-28 | Degussa Ag, 6000 Frankfurt | Kombination von flupirtin und anticholinergisch wirkenden spasmolytika |
| FI855016L (fi) * | 1985-06-28 | 1986-12-29 | Degussa | Synergistisk kombination av flupirtin och 4-acetamido-fenol. |
-
1991
- 1991-06-04 IN IN421CA1991 patent/IN172468B/en unknown
- 1991-07-04 AT AT95101189T patent/ATE206919T1/de not_active IP Right Cessation
- 1991-07-04 ES ES95101189T patent/ES2164111T3/es not_active Expired - Lifetime
- 1991-07-04 EP EP95101189A patent/EP0659410B1/de not_active Expired - Lifetime
- 1991-07-04 DE DE59107331T patent/DE59107331D1/de not_active Expired - Lifetime
- 1991-07-04 DK DK91111124.3T patent/DK0467164T3/da active
- 1991-07-04 DE DE4122166A patent/DE4122166A1/de not_active Ceased
- 1991-07-04 ES ES91111124T patent/ES2082887T3/es not_active Expired - Lifetime
- 1991-07-04 EP EP91111124A patent/EP0467164B1/de not_active Expired - Lifetime
- 1991-07-04 AT AT91111124T patent/ATE133564T1/de not_active IP Right Cessation
- 1991-07-04 DE DE59109222T patent/DE59109222D1/de not_active Expired - Lifetime
- 1991-07-04 DK DK95101189T patent/DK0659410T3/da active
- 1991-07-05 MC MC912203A patent/MC2272A1/xx unknown
- 1991-07-08 SK SK2101-91A patent/SK279567B6/sk not_active IP Right Cessation
- 1991-07-08 CZ CS912101A patent/CZ280879B6/cs not_active IP Right Cessation
- 1991-07-09 EG EG41291A patent/EG19814A/xx active
- 1991-07-09 RO RO147972A patent/RO108220B1/ro unknown
- 1991-07-10 US US07/726,408 patent/US5162346A/en not_active Expired - Lifetime
- 1991-07-10 MX MX9100160A patent/MX9100160A/es unknown
- 1991-07-11 PT PT98291A patent/PT98291B/pt not_active IP Right Cessation
- 1991-07-12 SI SI9111227A patent/SI9111227B/sl unknown
- 1991-07-12 AU AU80403/91A patent/AU634073B2/en not_active Expired
- 1991-07-12 IL IL9881091A patent/IL98810A/en not_active IP Right Cessation
- 1991-07-12 NO NO91912758A patent/NO912758L/no unknown
- 1991-07-12 NZ NZ238940A patent/NZ238940A/en not_active IP Right Cessation
- 1991-07-12 IE IE245191A patent/IE74688B1/en not_active IP Right Cessation
- 1991-07-12 RU SU915001150A patent/RU2070408C1/ru active
- 1991-07-12 ZA ZA915466A patent/ZA915466B/xx unknown
- 1991-07-12 CA CA002046943A patent/CA2046943C/en not_active Expired - Lifetime
- 1991-07-12 HU HU912359A patent/HU206973B/hu unknown
- 1991-07-13 KR KR1019910011967A patent/KR0182811B1/ko not_active Expired - Lifetime
- 1991-07-13 CN CN91104030A patent/CN1070700C/zh not_active Expired - Lifetime
-
1992
- 1992-06-01 US US07/890,730 patent/US5284861A/en not_active Expired - Lifetime
- 1992-09-30 HR HRP-1227/91A patent/HRP920667B1/xx not_active IP Right Cessation
- 1992-10-27 LV LVP-92-173A patent/LV10048B/lv unknown
-
1993
- 1993-09-03 LT LTIP919A patent/LT3593B/lt not_active IP Right Cessation
-
1996
- 1996-03-05 GR GR960400581T patent/GR3019179T3/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI9111227B (sl) | Farmacevtski preprat z aktivno materijo Flupirtin za zdravljenje bolezni, ki se nanašajo na napetost mišic | |
| BR0010498A (pt) | Composições modernas de medicamentos à base de compostos anticolinergicamente ativos e beta-miméticos | |
| BR0315283A (pt) | Composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto, e, método de tratamento de doenças neurológicas ou de doenças inflamatórias do trato respiratório superior | |
| BR0014525A (pt) | Processo de tratamento de distúrbios metabólicos, especialmente diabetes, ou uma doença ou condição associada com diabetes | |
| DE60316779D1 (de) | Thiadiazolylpiperazinderivate geeignet für die behandlung bzw. prävention von schmerzen | |
| KR900700089A (ko) | 전신성 피부 투과적 투여를 위한 약학적 조성물 | |
| BR0312216A (pt) | Composto, processo para a produção de um composto, composição farmacêutica, uso do composto, método para o tratamento de um sujeito que sofre de uma doença ou condição patológica e combinação de produto | |
| SE7910501L (sv) | Lekemedel for behandling av det centrala nervsystemet | |
| DE60126980D1 (de) | Therapeutische agentien und methoden ihrer verwendung zur behandlung von amyloidogenen erkrankungen | |
| BR0311558A (pt) | composto ou sal farmaceuticamente aceitável do mesmo, processo para preparar o mesmo, métodos para afetar os receptores de glutamato metabotrópicos ligados a camp, para administrar uma quantidade eficaz de um composto e para tratar um distúrbio neurológico e psiquiátrico em um paciente, e, formulação farmacêutica | |
| FI935847A0 (fi) | L-DOPA-esterkompositioner | |
| PT920865E (pt) | Utilizacao de ""norastemizole"" para o tratamento de disturbios alergicos | |
| ES8400742A1 (es) | Procedimiento de preparacion de las dibenzooxepinas sustituidas y de sus sales de adicion con un acido mineral u organi-co. | |
| MY104521A (en) | Treatment of depression. | |
| ES476428A1 (es) | Procedimiento para preparar tetrahidro-1,3,5-triazina-2,6- dionas. | |
| DE10299023I1 (de) | Antineoplastisch wirkender und den Antineoplastischen effekt Verstaerkender Wirkstoff | |
| IL90418A0 (en) | Condensed diazepinones,their preparation and pharmaceutical compositions containing them | |
| DK121789A (da) | 4,5,6,7-tetrahydroisothiazole oe4,5-caapyridinderivater | |
| DK249288A (da) | Substituerede silylalkylenaminer og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse | |
| BR9813020A (pt) | Utilização de derivados de ácido lisofosfatidìlico, compostos e drogas que contém esses compostos | |
| DE3275060D1 (en) | Use of beta-(1-adamantyl)-alpha, alpha-dimethylethylamine for the manufacture of a medicament for the treatment of otitis externa in dogs | |
| WO1988005299A1 (en) | Medicament containing local anesthetics and nucleosides and its use for treating muscular injuries | |
| GR3019176T3 (en) | Medicament containing a combination of AZT and amantadin for the treatment of AIDS. | |
| US3686409A (en) | Combination of l-dopa and 2-imino-5-phenyl-4-oxazolidinone used to treat parkinson{40 s disease | |
| KR910018026A (ko) | α-페닐-α피리딜알칸산 유도체를 함유하는 배뇨장애증상 치료제 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| IF | Valid on the event date |