ES8400742A1 - Procedimiento de preparacion de las dibenzooxepinas sustituidas y de sus sales de adicion con un acido mineral u organi-co. - Google Patents
Procedimiento de preparacion de las dibenzooxepinas sustituidas y de sus sales de adicion con un acido mineral u organi-co.Info
- Publication number
- ES8400742A1 ES8400742A1 ES519463A ES519463A ES8400742A1 ES 8400742 A1 ES8400742 A1 ES 8400742A1 ES 519463 A ES519463 A ES 519463A ES 519463 A ES519463 A ES 519463A ES 8400742 A1 ES8400742 A1 ES 8400742A1
- Authority
- ES
- Spain
- Prior art keywords
- medicaments
- processes
- preparation
- methods
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE LAS DIBENZOOXEPINAS SUSTITUIDAS Y DE SUS SALES DE ADICION CON UN ACIDO MINERAL U ORGANICO.SE SAPONIFICA UN COMPUESTO METILIDIENICO DE FORMULA (II) DONDE R Y RK SON IDENTICOS O DIFERENTES Y REPRESENTAN HIDROGENO, ALCOHILO INFERIOR, ALCOXI INFERIOR, TRIFLUOROMETILO O UN GRUPO ALCOHILTIO, A. ES OXIGENO O AZUFRE Y M Y M IGUALES O DIFERENTES, REPRESENTAN UN NUMERO ENTERO DE 1 O 2, EN MEDIO ALCALINO PARA FORMAR UN DERIVADO AMINADO DE FORMULA (IV) EN DONDE R1 Y R2 SON IGUALES O DIFERENTES Y REPRESENTAN HIDROGENO, ALCOHILO INFERIOR, ARALCOHILO INFERIOR O UN HIDROXI ALCOHILOINFERIOR, EN PRESENCIA DE UN AGENTE DE FUNCIONALIZACION DEL CARBOXILO PARA FORMAR LA AMIDA METILIDENICA DE FORMULA (V) QUE SE PUEDE REDUCIR O HIDROGENAR EN UN DERIVADO ETILAMINADO DE FORMULA GENERAL (I).SE UTILIZAN COMO AGENTES ANTIDEPRESORES, ANXIOLITICOS Y SEDANTES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8008023A FR2480283A1 (fr) | 1980-04-10 | 1980-04-10 | Nouveaux derives tricycliques, leurs procedes de preparation et leur utilisation comme medicament |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8400742A1 true ES8400742A1 (es) | 1983-11-16 |
ES519463A0 ES519463A0 (es) | 1983-11-16 |
Family
ID=9240699
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES500942A Expired ES8306483A1 (es) | 1980-04-10 | 1981-03-31 | Procedimiento de preparacion de las dibezooxepinas sustituidas y de sus sales de adicion con un acido mineral u organico |
ES519463A Granted ES519463A0 (es) | 1980-04-10 | 1983-02-01 | Procedimiento de preparacion de las dibenzooxepinas sustituidas y de sus sales de adicion con un acido mineral u organi-co. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES500942A Expired ES8306483A1 (es) | 1980-04-10 | 1981-03-31 | Procedimiento de preparacion de las dibezooxepinas sustituidas y de sus sales de adicion con un acido mineral u organico |
Country Status (23)
Country | Link |
---|---|
US (1) | US4459306A (es) |
EP (1) | EP0041410B1 (es) |
JP (1) | JPS56158780A (es) |
AR (1) | AR229026A1 (es) |
AT (1) | ATE5257T1 (es) |
AU (1) | AU538054B2 (es) |
CA (1) | CA1181068A (es) |
DD (1) | DD158242A5 (es) |
DE (1) | DE3161358D1 (es) |
DK (1) | DK159981A (es) |
ES (2) | ES8306483A1 (es) |
FI (1) | FI811059L (es) |
FR (1) | FR2480283A1 (es) |
GR (1) | GR75194B (es) |
IL (1) | IL62622A (es) |
MA (1) | MA19113A1 (es) |
NO (1) | NO811229L (es) |
NZ (1) | NZ196774A (es) |
OA (1) | OA06779A (es) |
PT (1) | PT72833B (es) |
SU (1) | SU1106444A3 (es) |
YU (1) | YU92481A (es) |
ZA (1) | ZA812379B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2094790B (en) * | 1981-03-13 | 1985-10-09 | Spofa Vereinigte Pharma Werke | Tricycle compounds |
ATE35262T1 (de) * | 1982-09-30 | 1988-07-15 | Merck Frosst Canada Inc | 6h-dibenz(b,e)(1,4)oxathiepin-derivate und deren herstellung. |
KR100330942B1 (ko) * | 1994-03-02 | 2002-11-16 | 악조 노벨 엔.브이. | 설하또는협측투여용약학조성물 |
JP4006796B2 (ja) | 1997-11-17 | 2007-11-14 | 株式会社日立製作所 | 個人情報管理方法および装置 |
ATE445838T1 (de) | 2001-07-25 | 2009-10-15 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
US6683072B1 (en) | 2003-02-04 | 2004-01-27 | Vela Pharmaceuticals, Inc. | Compositions and methods for treatment of irritable bowel syndrome and nonulcer dyspepsia |
US20050227961A1 (en) * | 2004-04-08 | 2005-10-13 | Vela Pharmaceuticals, Inc. | Compositions and methods for treatment of neuropathic pain, fibromyalgia and chronic fatigue syndrome |
DK1889198T3 (da) | 2005-04-28 | 2015-02-09 | Proteus Digital Health Inc | Farma-informatiksystem |
WO2008036682A2 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
ES2728225T3 (es) | 2009-02-20 | 2019-10-23 | 2 Bbb Medicines B V | Sistema de administración de fármacos a base de glutatión |
US8445002B2 (en) | 2009-05-06 | 2013-05-21 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
CN111377901A (zh) * | 2018-12-27 | 2020-07-07 | 华东理工大学 | 一种缩酚酸环醚类化合物及其制备方法与用途 |
JP2024513500A (ja) * | 2021-04-10 | 2024-03-25 | サノビオン ファーマシューティカルズ インク | Taar1及びセロトニン調節剤、及び医薬組成物、並びにそれらの使用方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES274329A1 (es) * | 1961-01-30 | 1962-06-01 | Geigy Ag J R | Procedimiento para la preparacion de nuevos compuestos de 1,5-benzodioxepano |
FR1312891A (fr) * | 1962-01-29 | 1962-12-21 | Geigy Ag J R | Nouveaux 1.5-benzo-dioxépannes et leur préparation |
FR1312889A (fr) * | 1962-01-29 | 1962-12-21 | Geigy Ag J R | Nouveaux benzo-dioxépannes et leur préparation |
US3821249A (en) * | 1970-03-13 | 1974-06-28 | En Nom Collectif Science Union | Dibenzothiazefin derivatives |
US3758528A (en) * | 1970-03-13 | 1973-09-11 | Science Union & Cie | Tricyclic compounds |
US4039676A (en) * | 1975-06-23 | 1977-08-02 | Ciba-Geigy Corporation | 2-piperidinoalkyl-1,4-benzodioxans |
US4335122A (en) * | 1981-03-18 | 1982-06-15 | Hoechst-Roussel Pharmaceuticals Inc. | Dihydro-dibenzoxepines-thiepines and -morphanthridones, compositions and use |
-
1980
- 1980-04-10 FR FR8008023A patent/FR2480283A1/fr active Granted
-
1981
- 1981-03-31 ES ES500942A patent/ES8306483A1/es not_active Expired
- 1981-04-03 MA MA19318A patent/MA19113A1/fr unknown
- 1981-04-06 US US06/251,052 patent/US4459306A/en not_active Expired - Fee Related
- 1981-04-06 CA CA000374790A patent/CA1181068A/fr not_active Expired
- 1981-04-06 FI FI811059A patent/FI811059L/fi not_active Application Discontinuation
- 1981-04-07 EP EP81400551A patent/EP0041410B1/fr not_active Expired
- 1981-04-07 AT AT81400551T patent/ATE5257T1/de not_active IP Right Cessation
- 1981-04-07 DE DE8181400551T patent/DE3161358D1/de not_active Expired
- 1981-04-08 GR GR64621A patent/GR75194B/el unknown
- 1981-04-09 IL IL62622A patent/IL62622A/xx unknown
- 1981-04-09 ZA ZA00812379A patent/ZA812379B/xx unknown
- 1981-04-09 NO NO811229A patent/NO811229L/no unknown
- 1981-04-09 PT PT72833A patent/PT72833B/pt unknown
- 1981-04-09 SU SU813269597A patent/SU1106444A3/ru active
- 1981-04-09 AR AR284911A patent/AR229026A1/es active
- 1981-04-09 JP JP5374381A patent/JPS56158780A/ja active Granted
- 1981-04-09 DK DK159981A patent/DK159981A/da not_active IP Right Cessation
- 1981-04-09 AU AU69340/81A patent/AU538054B2/en not_active Ceased
- 1981-04-09 YU YU00924/81A patent/YU92481A/xx unknown
- 1981-04-09 NZ NZ196774A patent/NZ196774A/xx unknown
- 1981-04-10 OA OA57367A patent/OA06779A/xx unknown
- 1981-04-10 DD DD81229155A patent/DD158242A5/de unknown
-
1983
- 1983-02-01 ES ES519463A patent/ES519463A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
US4459306A (en) | 1984-07-10 |
IL62622A (en) | 1984-10-31 |
PT72833A (fr) | 1981-05-01 |
OA06779A (fr) | 1982-12-31 |
DD158242A5 (de) | 1983-01-05 |
DE3161358D1 (en) | 1983-12-15 |
EP0041410A1 (fr) | 1981-12-09 |
ATE5257T1 (de) | 1983-11-15 |
AR229026A1 (es) | 1983-05-31 |
ES519463A0 (es) | 1983-11-16 |
PT72833B (fr) | 1982-07-26 |
ZA812379B (en) | 1982-04-28 |
CA1181068A (fr) | 1985-01-15 |
SU1106444A3 (ru) | 1984-07-30 |
EP0041410B1 (fr) | 1983-11-09 |
AU6934081A (en) | 1981-10-15 |
IL62622A0 (en) | 1981-06-29 |
MA19113A1 (fr) | 1981-12-31 |
AU538054B2 (en) | 1984-07-26 |
JPS56158780A (en) | 1981-12-07 |
FR2480283B1 (es) | 1983-09-23 |
JPS6116394B2 (es) | 1986-04-30 |
FR2480283A1 (fr) | 1981-10-16 |
DK159981A (da) | 1981-10-11 |
NZ196774A (en) | 1983-09-30 |
FI811059L (fi) | 1981-10-11 |
GR75194B (es) | 1984-07-13 |
YU92481A (en) | 1984-02-29 |
ES500942A0 (es) | 1983-06-01 |
ES8306483A1 (es) | 1983-06-01 |
NO811229L (no) | 1981-10-12 |
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