SI9012034B - Postopek za pripravo koncentrata kompleksa faktor VIII za koagulacijo krvi - von Willebrandov faktor iz skupne plazme - Google Patents

Postopek za pripravo koncentrata kompleksa faktor VIII za koagulacijo krvi - von Willebrandov faktor iz skupne plazme Download PDF

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Publication number
SI9012034B
SI9012034B SI9012034A SI9012034A SI9012034B SI 9012034 B SI9012034 B SI 9012034B SI 9012034 A SI9012034 A SI 9012034A SI 9012034 A SI9012034 A SI 9012034A SI 9012034 B SI9012034 B SI 9012034B
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SI
Slovenia
Prior art keywords
process according
chromatography
buffer
gel
carried out
Prior art date
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SI9012034A
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English (en)
Slovenian (sl)
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SI9012034A (en
Inventor
Miryana Burnouf-Radosevich
Thierry Burnouf
Original Assignee
Centre Regional De Transfusion Sanguine De Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Centre Regional De Transfusion Sanguine De Lille filed Critical Centre Regional De Transfusion Sanguine De Lille
Publication of SI9012034A publication Critical patent/SI9012034A/sl
Publication of SI9012034B publication Critical patent/SI9012034B/sl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Compounds Of Unknown Constitution (AREA)
SI9012034A 1989-09-05 1990-09-05 Postopek za pripravo koncentrata kompleksa faktor VIII za koagulacijo krvi - von Willebrandov faktor iz skupne plazme SI9012034B (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8911567A FR2651437A1 (fr) 1989-09-05 1989-09-05 Procede de preparation de concentre du complexe facteur viii-facteur von willebrand de la coagulation sanguine a partir de plasma total.
YU203490A YU48356B (sh) 1989-09-05 1990-09-05 Postupak za pravljenje koncentrata kompleksa faktora viii za koagulaciju krvi -von willebrand-ov kompleks iz ukupne plazme

Publications (2)

Publication Number Publication Date
SI9012034A SI9012034A (en) 1997-10-31
SI9012034B true SI9012034B (sl) 1999-12-31

Family

ID=9385124

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9012034A SI9012034B (sl) 1989-09-05 1990-09-05 Postopek za pripravo koncentrata kompleksa faktor VIII za koagulacijo krvi - von Willebrandov faktor iz skupne plazme

Country Status (24)

Country Link
US (1) US5679776A (lt)
EP (1) EP0416983B1 (lt)
AT (1) ATE91896T1 (lt)
AU (1) AU627618B2 (lt)
BR (1) BR9004626A (lt)
CA (1) CA2024667C (lt)
CZ (1) CZ277939B6 (lt)
DD (1) DD298110A5 (lt)
DE (1) DE69002427T2 (lt)
DK (1) DK0416983T3 (lt)
ES (1) ES2057475T3 (lt)
FI (1) FI95654C (lt)
FR (1) FR2651437A1 (lt)
HR (1) HRP920768B1 (lt)
HU (1) HU206378B (lt)
LT (1) LT3418B (lt)
LV (1) LV10053B (lt)
NO (1) NO178716C (lt)
PL (1) PL164754B1 (lt)
RU (1) RU2025129C1 (lt)
SI (1) SI9012034B (lt)
SK (1) SK279367B6 (lt)
UA (1) UA26847C2 (lt)
YU (1) YU48356B (lt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3904354A1 (de) * 1989-02-14 1990-08-16 Behringwerke Ag Pasteurisiertes, gereinigtes von willebrand-faktor-konzentrat und verfahren zu seiner herstellung
EP0399321B1 (en) * 1989-05-24 1993-06-23 Miles Inc. Gel filtration of heat treated factor viii
AT403991B (de) * 1990-04-04 1998-07-27 Atomic Austria Gmbh Alpinschi
AT403992B (de) * 1991-02-22 1998-07-27 Head Sport Ag Ski
DE4204694C3 (de) * 1992-02-01 1995-10-12 Octapharma Ag Verfahren zur Gewinnung von hochreinem, virusinaktiviertem Faktor VIII mittels Anionenaustauscher-Chromatographie
IT1256622B (it) * 1992-12-04 1995-12-12 Sclavo Spa Processo per l'estrazione del complesso fattore viii-fattore von willebrand (fviii:c-fvw) da plasma umano totale.
DE4430205A1 (de) * 1994-08-26 1996-02-29 Behringwerke Ag Zusammensetzungen, die als Gegenmittel für Blut-Antikoagulanzien geeignet sind und deren Verwendung
DE4435485C1 (de) * 1994-10-04 1996-03-21 Immuno Ag Verfahren zur Gewinnung von hochreinem von Willebrand-Faktor
AT403764B (de) 1996-03-15 1998-05-25 Immuno Ag Stabiler faktor viii/vwf-komplex
AT403765B (de) 1996-04-12 1998-05-25 Immuno Ag Verfahren zur herstellung einer präparation enthaltend einen hochgereinigten komplex
AT406373B (de) 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
KR20010031785A (ko) * 1997-11-05 2001-04-16 가마꾸라 아끼오 헤파린 보조인자 ｉｉ 제제 및 그 제조 방법
DE69811628T2 (de) * 1998-02-11 2003-12-18 Zlb Bioplasma Ag, Bern Verfahren zur Entfernung von Erregern übertragbarer spongiformer Encephalophatien aus Proteinlösungen
JP5149470B2 (ja) 1999-02-22 2013-02-20 バクスター・インターナショナル・インコーポレイテッド 新規のアルブミンを含有していない第ｖｉｉｉ因子処方物
DE19937218A1 (de) 1999-08-06 2001-02-08 Aventis Behring Gmbh Verfahren zur Reindarstellung der den Blutgerinnungsfaktor VII aktivierenden Protease, ihres Proenzyms oder eines Gemisches beider Proteine mittels Affinitätschromatographie
ES2229931B1 (es) * 2003-10-03 2006-01-16 Grifols, S.A. Composicion liquida bilogicamente estable de fviii, de fvw o del complejo fviii/fvw humanos.
FR2874216B1 (fr) 2004-08-16 2006-11-03 Lab Francais Du Fractionnement Procede de preparation d'un concentre de facteur von willebrand (fvw) par voie chromatographique et concentre de fvw susceptible d'etre ainsi obtenu
NZ593190A (en) 2008-11-07 2013-01-25 Baxter Int Factor viii formulations
US20150080309A1 (en) 2012-04-24 2015-03-19 Nova Nordisk A/S Compounds Suitable for Treatment of Haemophilia
WO2015066769A1 (en) 2013-11-08 2015-05-14 Csl Ltd. New method to concentrate von willebrand factor or complexes thereof
US9663553B2 (en) 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma
CN104231073B (zh) * 2014-09-25 2017-01-25 广东双林生物制药有限公司 一种人凝血因子viii的制备方法
CN105315365A (zh) * 2015-11-17 2016-02-10 上海洲跃生物科技有限公司 一种人抗凝血酶iii的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803115A (en) * 1972-05-17 1974-04-09 Baxter Laboratories Inc Stabilization of ahf using heparin
ES471858A1 (es) * 1977-07-25 1979-02-01 Monsanto Co Un metodo para separar el factor especifico de coagulacion de la sangre de una mezcla con otras proteinas de la sangre en un medio fluido
US4386068A (en) * 1980-02-26 1983-05-31 Cutter Laboratories, Inc. Antihemophilic factor concentrate and method for preparation
US4359463A (en) * 1980-11-26 1982-11-16 Rock Gail A Stabilization of Factor VIII activity in whole blood or blood plasma
US4435318A (en) * 1981-05-22 1984-03-06 Ionics, Incorporated Electrodialysis preparation of purified AHF concentrate
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4495175A (en) * 1982-08-05 1985-01-22 University Of Rochester Preparation of highly purified human antihemophilic factor
US4543210A (en) * 1984-10-04 1985-09-24 Miles Laboratories, Inc. Process for producing a high purity antihemophilic factor concentrate
US4952675A (en) * 1985-02-01 1990-08-28 New York University Method for purifying antihemophilic factor
FR2632309B1 (fr) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus

Also Published As

Publication number Publication date
CZ277939B6 (en) 1993-06-16
AU6221890A (en) 1992-03-12
DE69002427T2 (de) 1993-12-23
DD298110A5 (de) 1992-02-06
LT3418B (en) 1995-09-25
EP0416983B1 (fr) 1993-07-28
FR2651437B1 (lt) 1994-08-19
EP0416983A1 (fr) 1991-03-13
US5679776A (en) 1997-10-21
DE69002427D1 (de) 1993-09-02
DK0416983T3 (da) 1993-10-04
NO903865L (no) 1991-03-06
FI95654B (fi) 1995-11-30
SK431290A3 (en) 1998-10-07
CA2024667A1 (en) 1991-03-06
NO178716B (no) 1996-02-12
CZ431290A3 (en) 1993-01-13
BR9004626A (pt) 1992-03-24
SK279367B6 (sk) 1998-10-07
HU206378B (en) 1992-10-28
YU48356B (sh) 1998-07-10
LTIP263A (en) 1994-10-25
AU627618B2 (en) 1992-08-27
LV10053A (lv) 1994-05-10
HUT56858A (en) 1991-10-28
FI95654C (fi) 1996-03-11
HU905797D0 (en) 1991-03-28
SI9012034A (en) 1997-10-31
YU203490A (sh) 1993-05-28
ES2057475T3 (es) 1994-10-16
HRP920768B1 (en) 1998-12-31
FR2651437A1 (fr) 1991-03-08
PL286746A1 (en) 1991-05-06
FI904381A0 (fi) 1990-09-05
NO903865D0 (no) 1990-09-05
LV10053B (en) 1995-02-20
RU2025129C1 (ru) 1994-12-30
CA2024667C (en) 2001-07-31
PL164754B1 (pl) 1994-10-31
HRP920768A2 (en) 1995-02-28
ATE91896T1 (de) 1993-08-15
NO178716C (no) 1996-05-22
UA26847C2 (uk) 1999-12-29

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