SI3774862T1 - Novi analogi GLP-1 - Google Patents
Novi analogi GLP-1Info
- Publication number
- SI3774862T1 SI3774862T1 SI201930322T SI201930322T SI3774862T1 SI 3774862 T1 SI3774862 T1 SI 3774862T1 SI 201930322 T SI201930322 T SI 201930322T SI 201930322 T SI201930322 T SI 201930322T SI 3774862 T1 SI3774862 T1 SI 3774862T1
- Authority
- SI
- Slovenia
- Prior art keywords
- analogues
- novel glp
- glp
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201821013109 | 2018-04-05 | ||
IN201821040468 | 2018-10-26 | ||
IN201821040474 | 2018-10-26 | ||
PCT/IB2019/052835 WO2019193576A1 (en) | 2018-04-05 | 2019-04-05 | Novel glp-1 analogues |
EP19724915.4A EP3774862B1 (en) | 2018-04-05 | 2019-04-05 | Novel glp-1 analogues |
Publications (1)
Publication Number | Publication Date |
---|---|
SI3774862T1 true SI3774862T1 (sl) | 2022-10-28 |
Family
ID=66589592
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201930322T SI3774862T1 (sl) | 2018-04-05 | 2019-04-05 | Novi analogi GLP-1 |
Country Status (28)
Country | Link |
---|---|
US (5) | US11447535B2 (sl) |
EP (2) | EP4122954B1 (sl) |
JP (2) | JP7250814B2 (sl) |
KR (1) | KR20200141469A (sl) |
CN (1) | CN112236444A (sl) |
AU (2) | AU2019247936C1 (sl) |
BR (1) | BR112020020419A2 (sl) |
CA (1) | CA3095988A1 (sl) |
CL (1) | CL2020002574A1 (sl) |
CO (1) | CO2020012425A2 (sl) |
DK (1) | DK3774862T3 (sl) |
EC (1) | ECSP20070185A (sl) |
ES (1) | ES2925678T3 (sl) |
HR (1) | HRP20221054T1 (sl) |
HU (1) | HUE060135T2 (sl) |
IL (1) | IL277483A (sl) |
JO (1) | JOP20200251A1 (sl) |
LT (1) | LT3774862T (sl) |
MX (1) | MX2020010505A (sl) |
PE (1) | PE20211417A1 (sl) |
PH (1) | PH12020551591A1 (sl) |
PL (1) | PL3774862T3 (sl) |
PT (1) | PT3774862T (sl) |
RS (1) | RS63523B1 (sl) |
SG (1) | SG11202009467YA (sl) |
SI (1) | SI3774862T1 (sl) |
WO (1) | WO2019193576A1 (sl) |
ZA (1) | ZA202306729B (sl) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL3774862T3 (pl) * | 2018-04-05 | 2022-10-03 | Sun Pharmaceutical Industries Limited | Nowe analogi glp-1 |
TWI829687B (zh) | 2018-05-07 | 2024-01-21 | 丹麥商諾佛 儂迪克股份有限公司 | 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物 |
TW202216746A (zh) * | 2020-06-22 | 2022-05-01 | 印度商太陽製藥工業有限公司 | 長效型glp-1/gip雙重促效劑 |
TW202229323A (zh) * | 2020-10-17 | 2022-08-01 | 印度商太陽製藥工業有限公司 | 新型glp-1/gip雙重促效劑 |
CN114685646B (zh) * | 2020-12-31 | 2023-04-07 | 厦门赛诺邦格生物科技股份有限公司 | 一种多肽侧链类似物的制备方法及其应用 |
CN116710462A (zh) | 2021-01-20 | 2023-09-05 | 维京治疗公司 | 用于治疗代谢病症和肝病的组合物和方法 |
CN116514952B (zh) * | 2022-10-13 | 2024-02-02 | 江苏师范大学 | 一类glp-1类似物及其应用 |
Family Cites Families (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6849708B1 (en) | 1986-05-05 | 2005-02-01 | The General Hospital Corporation | Insulinotropic hormone and uses thereof |
UA72181C2 (uk) | 1996-08-30 | 2005-02-15 | Ново Нордіск А/С | Похідна глюкагоноподібного пептиду-1 (варіанти), фармацевтична композиція та спосіб одержання лікувального засобу (варіанти), спосіб лікування діабету (варіанти) і ожиріння |
US6268343B1 (en) | 1996-08-30 | 2001-07-31 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
ATE466027T1 (de) | 1998-02-27 | 2010-05-15 | Novo Nordisk As | Abkömmlinge von glp-1 analogen |
WO1999043708A1 (en) | 1998-02-27 | 1999-09-02 | Novo Nordisk A/S | Glp-1 derivatives of glp-1 and exendin with protracted profile of action |
EP1056774A1 (en) | 1998-02-27 | 2000-12-06 | Novo Nordisk A/S | N-terminally truncated glp-1 derivatives |
EP1062240B1 (en) | 1998-02-27 | 2010-04-28 | Novo Nordisk A/S | N-terminally modified glp-1 derivatives |
FR2777283B1 (fr) | 1998-04-10 | 2000-11-24 | Adir | Nouveaux composes peptidiques analogues du glucagon-peptide- 1 (7-37), leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
BR9915961A (pt) | 1998-12-07 | 2001-08-21 | Sod Conseils Rech Applic | Análogos de glp-1 |
DE60124710T2 (de) | 2000-06-16 | 2007-09-13 | Eli Lilly And Co., Indianapolis | Analoge des glucagon ähnlichen peptid-1 |
SI1724284T1 (sl) | 2000-12-07 | 2009-12-31 | Lilly Co Eli | Glp-1 fuzijski proteini |
EP1585959A4 (en) | 2002-01-08 | 2007-11-14 | Lilly Co Eli | PEPTIDE-1 ANALOGUES OF EXTENSION GLUCAGON TYPE |
CA2502118A1 (en) | 2002-10-11 | 2004-05-06 | Sanwa Kagaku Kenkyusho Co., Ltd. | Glp-1 derivatives and transmicosal absorption preparations thereof |
EP1626981A4 (en) | 2003-03-04 | 2006-11-22 | Biorexis Pharmaceutical Corp | PROTEINS PROTECTED AGAINST DIPEPTIDYLPEPTIDASE |
CN102174102A (zh) | 2003-05-15 | 2011-09-07 | 塔夫茨大学信托人 | 肽和多肽药物的稳定类似物 |
EP2932981B1 (en) | 2003-09-19 | 2021-06-16 | Novo Nordisk A/S | Albumin-binding derivatives of GLP-1 |
CA2551039C (en) | 2003-12-16 | 2013-01-29 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R | Analogues of glp-1 |
EP1799710A2 (en) | 2004-10-07 | 2007-06-27 | Novo Nordisk A/S | Protracted glp-1 compounds |
TWI362392B (en) * | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
JP5755398B2 (ja) * | 2005-03-18 | 2015-07-29 | ノヴォ ノルディスク アー/エス | 伸長されたglp−1化合物 |
WO2006121860A2 (en) | 2005-05-06 | 2006-11-16 | Bayer Pharmaceuticals Corporation | Glucagon-like peptide 1 (glp-1) receptor agonists and their pharmacological methods of use |
US8318668B2 (en) | 2005-09-08 | 2012-11-27 | Trustees Of Tufts College | Stabilized GLP-1 analogs |
ES2397289T3 (es) | 2005-09-22 | 2013-03-06 | Biocompatibles Uk Ltd. | Polipéptidos de fusión de GLP-1 (péptido 1 de tipo glucagón) con resistencia a peptidasa incrementada |
EP2190460B1 (en) | 2007-09-05 | 2014-12-17 | Novo Nordisk A/S | Peptides derivatized with a-b-c-d- and their therapeutical use |
ES2558155T3 (es) | 2007-10-30 | 2016-02-02 | Indiana University Research And Technology Corporation | Compuestos que muestran actividad antagonista de glucacón y agonista de GLP-1 |
CA2784757A1 (en) | 2009-12-16 | 2011-07-07 | Novo Nordisk A/S | Double-acylated glp-1 derivatives |
WO2011134284A1 (zh) | 2010-04-27 | 2011-11-03 | 浙江贝达药业有限公司 | 胰高血糖素样肽-1类似物及其应用 |
WO2012016419A1 (zh) | 2010-08-06 | 2012-02-09 | 浙江贝达药业有限公司 | Glp-1衍生物及其应用 |
WO2012062803A1 (en) | 2010-11-09 | 2012-05-18 | Novo Nordisk A/S | Double-acylated glp-1 derivatives |
ES2612278T3 (es) | 2011-04-12 | 2017-05-16 | Novo Nordisk A/S | Derivados de GLP-1 doble-acilados |
WO2012150503A2 (en) | 2011-05-03 | 2012-11-08 | Zealand Pharma A/S | Glu-glp-1 dual agonist signaling-selective compounds |
ES2626013T3 (es) | 2011-09-06 | 2017-07-21 | Novo Nordisk A/S | Derivados de GLP-1 |
EP2578599A1 (en) | 2011-10-07 | 2013-04-10 | LanthioPep B.V. | Cyclic analogs of GLP-1 and GLP-1 related peptides |
US10000542B2 (en) | 2012-05-08 | 2018-06-19 | Novo Nordisk A/S | Double-acylated GLP-1 derivatives |
US11274135B2 (en) | 2012-05-08 | 2022-03-15 | Novo Nordisk A/S | Double-acylated GLP-1 derivatives |
SG11201407860PA (en) | 2012-06-14 | 2014-12-30 | Sanofi Sa | Exendin-4 peptide analogues |
UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
TWI674270B (zh) | 2012-12-11 | 2019-10-11 | 英商梅迪繆思有限公司 | 用於治療肥胖之升糖素與glp-1共促效劑 |
WO2014096150A1 (en) | 2012-12-21 | 2014-06-26 | Sanofi | Dual glp1/gip or trigonal glp1/gip/glucagon agonists |
JP6475233B2 (ja) | 2013-06-20 | 2019-02-27 | ノヴォ ノルディスク アー/エス | Glp−1誘導体及びその使用 |
WO2014209886A1 (en) | 2013-06-23 | 2014-12-31 | Wisconsin Alumni Research Foundation | Alpha/beta-polypeptide analogs of glucagon-like peptid-1 |
EP3016975B1 (en) | 2013-07-04 | 2019-01-16 | Novo Nordisk A/S | Derivatives of glp-1 like peptides, and uses thereof |
JP6599863B2 (ja) | 2013-08-15 | 2019-10-30 | ノヴォ ノルディスク アー/エス | Glp−1誘導体及びその使用 |
PT3057984T (pt) * | 2013-10-17 | 2018-10-24 | Boehringer Ingelheim Int | Análogos de glucagon acilados |
TW201609800A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 做為雙重glp-1/升糖素受體促效劑之艾塞那肽-4胜肽類似物 |
SG10201805039UA (en) | 2013-12-13 | 2018-07-30 | Medimmune Ltd | Protease resistant peptides |
WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
JP6730278B2 (ja) | 2014-11-27 | 2020-07-29 | ノヴォ ノルディスク アー/エス | Glp−1誘導体及びその使用 |
CN107108714B (zh) | 2014-12-17 | 2022-02-08 | 诺和诺德股份有限公司 | Glp-1衍生物及其用途 |
TWI726889B (zh) | 2015-06-10 | 2021-05-11 | 英商梅迪繆思有限公司 | 蛋白酶抗性之脂化肽 |
WO2017035432A1 (en) | 2015-08-26 | 2017-03-02 | Robert Doyle | Coagonists of glucagon-like peptide 1 receptor and neuropeptide y2 receptor |
ES2835033T3 (es) | 2016-03-03 | 2021-06-21 | Novo Nordisk As | Derivados de GLP-1 y sus usos |
MX2018014966A (es) | 2016-06-09 | 2019-08-14 | Medimmune Ltd | Peptidos monolipidados resistentes a proteasas. |
WO2018083335A1 (en) | 2016-11-07 | 2018-05-11 | Novo Nordisk A/S | Dchbs-active esters of peg compounds and their use |
TW201833131A (zh) | 2016-12-02 | 2018-09-16 | 法商賽諾菲公司 | 作為胜肽類glp1/升糖素/gip受體促效劑之新化合物 |
WO2018178796A1 (en) * | 2017-03-27 | 2018-10-04 | Sun Pharmaceutical Industries Limited | Method for making kex1 protease sensitive polypeptides using yeast strain |
CN111819191A (zh) | 2018-03-09 | 2020-10-23 | 恩细贝普有限公司 | 利拉鲁肽、索马鲁肽和glp-1的化学酶促合成 |
PL3774862T3 (pl) * | 2018-04-05 | 2022-10-03 | Sun Pharmaceutical Industries Limited | Nowe analogi glp-1 |
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2019
- 2019-04-05 PL PL19724915.4T patent/PL3774862T3/pl unknown
- 2019-04-05 LT LTEPPCT/IB2019/052835T patent/LT3774862T/lt unknown
- 2019-04-05 CN CN201980037166.1A patent/CN112236444A/zh active Pending
- 2019-04-05 EP EP22177403.7A patent/EP4122954B1/en active Active
- 2019-04-05 KR KR1020207031696A patent/KR20200141469A/ko active Search and Examination
- 2019-04-05 ES ES19724915T patent/ES2925678T3/es active Active
- 2019-04-05 WO PCT/IB2019/052835 patent/WO2019193576A1/en active Application Filing
- 2019-04-05 JO JOP/2020/0251A patent/JOP20200251A1/ar unknown
- 2019-04-05 AU AU2019247936A patent/AU2019247936C1/en active Active
- 2019-04-05 SI SI201930322T patent/SI3774862T1/sl unknown
- 2019-04-05 EP EP19724915.4A patent/EP3774862B1/en active Active
- 2019-04-05 HR HRP20221054TT patent/HRP20221054T1/hr unknown
- 2019-04-05 DK DK19724915.4T patent/DK3774862T3/da active
- 2019-04-05 MX MX2020010505A patent/MX2020010505A/es unknown
- 2019-04-05 HU HUE19724915A patent/HUE060135T2/hu unknown
- 2019-04-05 JP JP2020553627A patent/JP7250814B2/ja active Active
- 2019-04-05 RS RS20220814A patent/RS63523B1/sr unknown
- 2019-04-05 US US16/376,190 patent/US11447535B2/en active Active
- 2019-04-05 SG SG11202009467YA patent/SG11202009467YA/en unknown
- 2019-04-05 PT PT197249154T patent/PT3774862T/pt unknown
- 2019-04-05 BR BR112020020419-6A patent/BR112020020419A2/pt unknown
- 2019-04-05 PE PE2020001535A patent/PE20211417A1/es unknown
- 2019-04-05 CA CA3095988A patent/CA3095988A1/en active Pending
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2020
- 2020-08-04 US US16/985,207 patent/US11242373B2/en active Active
- 2020-09-21 IL IL277483A patent/IL277483A/en unknown
- 2020-09-29 PH PH12020551591A patent/PH12020551591A1/en unknown
- 2020-10-02 CO CONC2020/0012425A patent/CO2020012425A2/es unknown
- 2020-10-05 CL CL2020002574A patent/CL2020002574A1/es unknown
- 2020-11-05 EC ECSENADI202070185A patent/ECSP20070185A/es unknown
- 2020-12-28 US US17/134,982 patent/US11485766B2/en active Active
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2022
- 2022-08-01 US US17/816,577 patent/US11873328B2/en active Active
- 2022-08-12 US US17/819,466 patent/US11866477B2/en active Active
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2023
- 2023-03-22 JP JP2023045498A patent/JP2023078367A/ja active Pending
- 2023-06-01 AU AU2023203430A patent/AU2023203430A1/en active Pending
- 2023-06-30 ZA ZA2023/06729A patent/ZA202306729B/en unknown
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