SI3068786T1 - Pirazolopirimidinske spojine - Google Patents
Pirazolopirimidinske spojineInfo
- Publication number
- SI3068786T1 SI3068786T1 SI201430815T SI201430815T SI3068786T1 SI 3068786 T1 SI3068786 T1 SI 3068786T1 SI 201430815 T SI201430815 T SI 201430815T SI 201430815 T SI201430815 T SI 201430815T SI 3068786 T1 SI3068786 T1 SI 3068786T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pyrazolopyrimidine compounds
- pyrazolopyrimidine
- compounds
- Prior art date
Links
- OGEBRHQLRGFBNV-RZDIXWSQSA-N chembl2036808 Chemical class C12=NC(NCCCC)=NC=C2C(C=2C=CC(F)=CC=2)=NN1C[C@H]1CC[C@H](N)CC1 OGEBRHQLRGFBNV-RZDIXWSQSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261727581P | 2012-11-16 | 2012-11-16 | |
| US201361808152P | 2013-04-03 | 2013-04-03 | |
| PCT/CA2013/000957 WO2014075168A1 (en) | 2012-11-16 | 2013-11-15 | Pyrazolopyrimidine compounds |
| PCT/CA2014/051091 WO2015070349A1 (en) | 2012-11-16 | 2014-11-14 | Pyrazolopyrimidine compounds |
| EP14861448.0A EP3068786B1 (en) | 2012-11-16 | 2014-11-14 | Pyrazolopyrimidine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3068786T1 true SI3068786T1 (sl) | 2018-09-28 |
Family
ID=50730425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201430815T SI3068786T1 (sl) | 2012-11-16 | 2014-11-14 | Pirazolopirimidinske spojine |
Country Status (24)
| Country | Link |
|---|---|
| US (9) | US9573954B2 (enExample) |
| EP (2) | EP2920181B1 (enExample) |
| JP (1) | JP6377068B2 (enExample) |
| CN (1) | CN105793261B (enExample) |
| AU (1) | AU2013344716B2 (enExample) |
| BR (1) | BR112016010080B1 (enExample) |
| CA (1) | CA2889919C (enExample) |
| CY (1) | CY1120480T1 (enExample) |
| DK (1) | DK3068786T3 (enExample) |
| ES (1) | ES2686097T3 (enExample) |
| HR (1) | HRP20181041T1 (enExample) |
| HU (1) | HUE039351T2 (enExample) |
| IL (1) | IL245187B (enExample) |
| LT (1) | LT3068786T (enExample) |
| ME (1) | ME03093B (enExample) |
| MX (1) | MX373713B (enExample) |
| NZ (1) | NZ707432A (enExample) |
| PL (1) | PL3068786T3 (enExample) |
| PT (1) | PT3068786T (enExample) |
| RS (1) | RS57481B1 (enExample) |
| SG (1) | SG11201603102TA (enExample) |
| SI (1) | SI3068786T1 (enExample) |
| TW (1) | TWI679201B (enExample) |
| WO (2) | WO2014075168A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9573954B2 (en) | 2012-11-16 | 2017-02-21 | University Health Network | Pyrazolopyrimidine compounds |
| JP6095857B2 (ja) * | 2013-11-15 | 2017-03-15 | ユニバーシティ・ヘルス・ネットワーク | ピラゾロピリミジン化合物 |
| EP3191095A2 (en) * | 2014-09-08 | 2017-07-19 | Dana Farber Cancer Institute, Inc. | Methods of treating cancer comprising administering a ppar-gamma agonist |
| WO2016073891A1 (en) | 2014-11-06 | 2016-05-12 | Lysosomal Therapeutics Inc. | Substituted pyrrolo[1,2-a]pyrimidines and their use in the treatment of medical disorders |
| US20170333435A1 (en) | 2014-11-06 | 2017-11-23 | Lysosomal Therapeutics Inc. | Substituted imidazo[1,5-a]pyrimidines and their use in the treatment of medical disorders |
| KR102662215B1 (ko) | 2014-11-06 | 2024-05-02 | 비알 - 알&디 인베스트먼츠, 에스.에이. | 치환된 피라졸로(1,5-a)피리미딘 및 의학적 장애의 치료에서의 그의 용도 |
| CA2989722C (en) * | 2015-06-24 | 2023-09-19 | Jacob Westman | Pyrazolo[1,5-a]triazin-4-amine derivatives useful in therapy |
| WO2017176961A1 (en) | 2016-04-06 | 2017-10-12 | Lysosomal Therapeutics Inc. | Imidazo [1,5-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders |
| US11192892B2 (en) | 2016-04-06 | 2021-12-07 | Bial—R&D Investments, S.A. | Substituted pyrazolo[1,5-a]pyrimidines for the treatment of medical disorders |
| JP7034935B2 (ja) | 2016-04-06 | 2022-03-14 | リソソーマル・セラピューティクス・インコーポレイテッド | ピロロ［１，２－ａ］ピリミジニルカルボキサミド化合物および医学的障害の処置におけるその使用 |
| US11345698B2 (en) | 2016-05-05 | 2022-05-31 | Bial—R&D Investments, S.A. | Substituted imidazo[1,2-a]pyridines, substituted imidazo[1,2-a]pyrazines, related compounds, and their use in the treatment of medical disorders |
| WO2017192930A1 (en) | 2016-05-05 | 2017-11-09 | Lysosomal Therapeutics Inc. | SUBSTITUTED IMIDAZO[1,2-b]PYRIDAZINES, SUBSTITUTED IMIDAZO[1,5-b]PYRIDAZINES, RELATED COMPOUNDS, AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS |
| JP6961675B2 (ja) * | 2016-07-18 | 2021-11-05 | ユニバーシティー ヘルス ネットワーク | Ｔｔｋ阻害剤の固体形態 |
| MY205416A (en) | 2017-07-28 | 2024-10-21 | Takeda Pharmaceuticals Co | Tyk2 inhibitors and uses thereof |
| WO2019023786A1 (en) * | 2017-08-01 | 2019-02-07 | University Health Network | COMBINED THERAPIES FOR THE INHIBITION OF TTK PROTEIN KINASE |
| CN112334135A (zh) * | 2018-05-23 | 2021-02-05 | 大学健康网络 | 治疗特征在于纺锤体和着丝粒相关复合物亚基3(ska3)基因的高表达水平的癌症的方法 |
| SG11202104229WA (en) | 2018-10-30 | 2021-05-28 | Kronos Bio Inc | Compounds, compositions, and methods for modulating cdk9 activity |
| CN111377925B (zh) * | 2018-12-28 | 2024-03-12 | 四川科伦博泰生物医药股份有限公司 | 嘌呤类衍生物、其制备方法及其在医药上的应用 |
| CN112142744A (zh) * | 2019-06-28 | 2020-12-29 | 上海瑛派药业有限公司 | 取代的稠合杂芳双环化合物作为激酶抑制剂及其应用 |
| TW202146416A (zh) * | 2019-12-11 | 2021-12-16 | 德商拜耳廠股份有限公司 | 吡唑并三𠯤 |
| CN113773324B (zh) * | 2021-09-07 | 2022-07-26 | 武汉九州钰民医药科技有限公司 | 抗肿瘤药cfi-402257的合成制备工艺 |
| CN116396298A (zh) * | 2023-06-06 | 2023-07-07 | 四川维亚本苑生物科技有限公司 | CDK Ligand-1的中间体XII及CDK Ligand-1的制备方法 |
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| JPH04156453A (ja) | 1990-10-19 | 1992-05-28 | Konica Corp | 新規な写真用カプラー |
| US6191131B1 (en) | 1997-07-23 | 2001-02-20 | Dupont Pharmaceuticals Company | Azolo triazines and pyrimidines |
| US6124289A (en) | 1996-07-24 | 2000-09-26 | Dupont Pharmaceuticals Co. | Azolo triazines and pyrimidines |
| US6060478A (en) | 1996-07-24 | 2000-05-09 | Dupont Pharmaceuticals | Azolo triazines and pyrimidines |
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| WO2001023388A2 (en) | 1999-09-30 | 2001-04-05 | Neurogen Corporation | AMINO SUBSTITUTED PYRAZOLO[1,5,-a]-1,5-PYRIMIDINES AND PYRAZOLO[1,5-a]-1,3,5-TRIAZINES |
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| PL382706A1 (pl) | 2002-08-26 | 2007-11-26 | Takeda Pharmaceutical Company Limited | Związek modulujący receptor wapnia i jego zastosowanie |
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| WO2004087707A1 (en) | 2003-03-31 | 2004-10-14 | Vernalis (Cambridge) Limited | Pyrazolopyrimidine compounds and their use in medicine |
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| US9573954B2 (en) | 2012-11-16 | 2017-02-21 | University Health Network | Pyrazolopyrimidine compounds |
-
2013
- 2013-11-15 US US14/443,072 patent/US9573954B2/en active Active
- 2013-11-15 JP JP2015542121A patent/JP6377068B2/ja active Active
- 2013-11-15 EP EP13855919.0A patent/EP2920181B1/en active Active
- 2013-11-15 WO PCT/CA2013/000957 patent/WO2014075168A1/en not_active Ceased
- 2013-11-15 AU AU2013344716A patent/AU2013344716B2/en active Active
- 2013-11-15 NZ NZ707432A patent/NZ707432A/en unknown
- 2013-11-15 CA CA2889919A patent/CA2889919C/en active Active
-
2014
- 2014-11-14 ES ES14861448.0T patent/ES2686097T3/es active Active
- 2014-11-14 PT PT148614480T patent/PT3068786T/pt unknown
- 2014-11-14 DK DK14861448.0T patent/DK3068786T3/en active
- 2014-11-14 MX MX2016006336A patent/MX373713B/es active IP Right Grant
- 2014-11-14 SI SI201430815T patent/SI3068786T1/sl unknown
- 2014-11-14 EP EP14861448.0A patent/EP3068786B1/en active Active
- 2014-11-14 RS RS20180775A patent/RS57481B1/sr unknown
- 2014-11-14 WO PCT/CA2014/051091 patent/WO2015070349A1/en not_active Ceased
- 2014-11-14 SG SG11201603102TA patent/SG11201603102TA/en unknown
- 2014-11-14 HR HRP20181041TT patent/HRP20181041T1/hr unknown
- 2014-11-14 BR BR112016010080-8A patent/BR112016010080B1/pt active IP Right Grant
- 2014-11-14 TW TW103139540A patent/TWI679201B/zh active
- 2014-11-14 LT LTEP14861448.0T patent/LT3068786T/lt unknown
- 2014-11-14 ME MEP-2018-171A patent/ME03093B/me unknown
- 2014-11-14 CN CN201480062623.XA patent/CN105793261B/zh active Active
- 2014-11-14 PL PL14861448T patent/PL3068786T3/pl unknown
- 2014-11-14 HU HUE14861448A patent/HUE039351T2/hu unknown
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2015
- 2015-10-29 US US14/926,977 patent/US9657025B2/en active Active
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2016
- 2016-04-18 IL IL245187A patent/IL245187B/en active IP Right Grant
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2017
- 2017-02-16 US US15/434,275 patent/US10106545B2/en active Active
- 2017-05-18 US US15/598,402 patent/US10167289B2/en active Active
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2018
- 2018-07-30 CY CY20181100786T patent/CY1120480T1/el unknown
- 2018-10-09 US US16/155,846 patent/US10570143B2/en active Active
- 2018-12-19 US US16/225,970 patent/US20190322669A1/en not_active Abandoned
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2020
- 2020-05-21 US US16/880,192 patent/US20210009595A1/en not_active Abandoned
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2021
- 2021-11-08 US US17/521,255 patent/US20220204511A1/en not_active Abandoned
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2023
- 2023-12-20 US US18/391,047 patent/US20240287077A1/en not_active Abandoned
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| GB201218758D0 (en) | Compounds | |
| GB201218776D0 (en) | Compounds | |
| GB201218774D0 (en) | Compounds | |
| GB201218018D0 (en) | Compounds |