HRP20181041T1 - Pirazolopirimidinski spojevi - Google Patents
Pirazolopirimidinski spojeviInfo
- Publication number
- HRP20181041T1 HRP20181041T1 HRP20181041TT HRP20181041T HRP20181041T1 HR P20181041 T1 HRP20181041 T1 HR P20181041T1 HR P20181041T T HRP20181041T T HR P20181041TT HR P20181041 T HRP20181041 T HR P20181041T HR P20181041 T1 HRP20181041 T1 HR P20181041T1
- Authority
- HR
- Croatia
- Prior art keywords
- pyrazolopyrimidine compounds
- pyrazolopyrimidine
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261727581P | 2012-11-16 | 2012-11-16 | |
| US201361808152P | 2013-04-03 | 2013-04-03 | |
| PCT/CA2013/000957 WO2014075168A1 (en) | 2012-11-16 | 2013-11-15 | Pyrazolopyrimidine compounds |
| PCT/CA2014/051091 WO2015070349A1 (en) | 2012-11-16 | 2014-11-14 | Pyrazolopyrimidine compounds |
| EP14861448.0A EP3068786B1 (en) | 2012-11-16 | 2014-11-14 | Pyrazolopyrimidine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20181041T1 true HRP20181041T1 (hr) | 2018-09-21 |
Family
ID=50730425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20181041TT HRP20181041T1 (hr) | 2012-11-16 | 2014-11-14 | Pirazolopirimidinski spojevi |
Country Status (24)
| Country | Link |
|---|---|
| US (9) | US9573954B2 (enExample) |
| EP (2) | EP2920181B1 (enExample) |
| JP (1) | JP6377068B2 (enExample) |
| CN (1) | CN105793261B (enExample) |
| AU (1) | AU2013344716B2 (enExample) |
| BR (1) | BR112016010080B1 (enExample) |
| CA (1) | CA2889919C (enExample) |
| CY (1) | CY1120480T1 (enExample) |
| DK (1) | DK3068786T3 (enExample) |
| ES (1) | ES2686097T3 (enExample) |
| HR (1) | HRP20181041T1 (enExample) |
| HU (1) | HUE039351T2 (enExample) |
| IL (1) | IL245187B (enExample) |
| LT (1) | LT3068786T (enExample) |
| ME (1) | ME03093B (enExample) |
| MX (1) | MX373713B (enExample) |
| NZ (1) | NZ707432A (enExample) |
| PL (1) | PL3068786T3 (enExample) |
| PT (1) | PT3068786T (enExample) |
| RS (1) | RS57481B1 (enExample) |
| SG (1) | SG11201603102TA (enExample) |
| SI (1) | SI3068786T1 (enExample) |
| TW (1) | TWI679201B (enExample) |
| WO (2) | WO2014075168A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2920181B1 (en) | 2012-11-16 | 2019-01-09 | University Health Network | Pyrazolopyrimidine compounds |
| EA029372B1 (ru) * | 2013-11-15 | 2018-03-30 | Юниверсити Хелс Нетуорк | Пиразолопиримидиновые соединения |
| EP3191095A2 (en) * | 2014-09-08 | 2017-07-19 | Dana Farber Cancer Institute, Inc. | Methods of treating cancer comprising administering a ppar-gamma agonist |
| CA2966581A1 (en) | 2014-11-06 | 2016-05-12 | Lysosomal Therapeutics Inc. | Substituted pyrrolo[1,2-a]pyrimidines and their use in the treatment of medical disorders |
| HRP20240644T1 (hr) | 2014-11-06 | 2024-08-02 | Bial-R&D Investments, S.A. | Supstituirani pirazolo(1,5-a)pirimidini i njihova uporaba u liječenju medicinskih poremećaja |
| US20170333435A1 (en) | 2014-11-06 | 2017-11-23 | Lysosomal Therapeutics Inc. | Substituted imidazo[1,5-a]pyrimidines and their use in the treatment of medical disorders |
| RU2712196C2 (ru) * | 2015-06-24 | 2020-01-24 | Куровир Аб | Производные пиразоло[1,5-a]триазин-4-амина, применимые в терапии |
| JP7046827B2 (ja) | 2016-04-06 | 2022-04-04 | リソソーマル・セラピューティクス・インコーポレイテッド | イミダゾ［１，５－ａ］ピリミジニルカルボキサミド化合物および医学的障害の処置におけるその使用 |
| US11124516B2 (en) | 2016-04-06 | 2021-09-21 | BIAL-BioTech Investments, Inc. | Pyrrolo[1,2-A]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders |
| SG11201808830YA (en) | 2016-04-06 | 2018-11-29 | Lysosomal Therapeutics Inc | Pyrazolo[1,5-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders |
| JP7164774B2 (ja) | 2016-05-05 | 2022-11-02 | ビアル－アール・アンド・ディ・インベストメンツ・ソシエダーデ・アノニマ | 置換イミダゾ［１，２－ｂ］ピリダジン、置換イミダゾ［１，５－ｂ］ピリダジン、関連化合物、および医学的障害の治療におけるその使用 |
| WO2017192931A1 (en) | 2016-05-05 | 2017-11-09 | Lysosomal Therapeutics Inc. | SUBSTITUTED IMDAZO[1,2-α]PYRIDINES, SUBSTITUTED IMIDAZO[1,2-α]PYRAZINES, RELATED COMPOUNDS, AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS |
| RU2753905C2 (ru) * | 2016-07-18 | 2021-08-24 | Юниверсити Хелс Нетуорк | Твердые формы ингибитора ttk |
| JP7216705B2 (ja) | 2017-07-28 | 2023-02-02 | ニンバス ラクシュミ， インコーポレイテッド | Ｔｙｋ２阻害剤およびその使用方法 |
| WO2019023786A1 (en) * | 2017-08-01 | 2019-02-07 | University Health Network | COMBINED THERAPIES FOR THE INHIBITION OF TTK PROTEIN KINASE |
| CA3101035A1 (en) * | 2018-05-23 | 2019-11-28 | University Health Network | Methods of treating cancers characterized by a high expression level of spindle and kinetochore associated complex subunit 3 (ska3) gene |
| MY210039A (en) | 2018-10-30 | 2025-08-22 | Kronos Bio Inc | Compounds, compositions, and methods for modulating cdk9 activity |
| CN111377925B (zh) * | 2018-12-28 | 2024-03-12 | 四川科伦博泰生物医药股份有限公司 | 嘌呤类衍生物、其制备方法及其在医药上的应用 |
| CN112142744A (zh) * | 2019-06-28 | 2020-12-29 | 上海瑛派药业有限公司 | 取代的稠合杂芳双环化合物作为激酶抑制剂及其应用 |
| TW202146416A (zh) * | 2019-12-11 | 2021-12-16 | 德商拜耳廠股份有限公司 | 吡唑并三𠯤 |
| CN113773324B (zh) * | 2021-09-07 | 2022-07-26 | 武汉九州钰民医药科技有限公司 | 抗肿瘤药cfi-402257的合成制备工艺 |
| CN116396298A (zh) * | 2023-06-06 | 2023-07-07 | 四川维亚本苑生物科技有限公司 | CDK Ligand-1的中间体XII及CDK Ligand-1的制备方法 |
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| US6313124B1 (en) | 1997-07-23 | 2001-11-06 | Dupont Pharmaceuticals Company | Tetrazine bicyclic compounds |
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| US6060478A (en) | 1996-07-24 | 2000-05-09 | Dupont Pharmaceuticals | Azolo triazines and pyrimidines |
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| DE602004025504D1 (de) | 2003-12-23 | 2010-03-25 | Novartis Ag | Bicyclische heterocyclische p-38-kinase-inhibitoren |
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| EP2651950A1 (en) * | 2010-12-17 | 2013-10-23 | Bayer Intellectual Property GmbH | 6 substituted imidazopyrazines for use as mps-1 and tkk inhibitors in the treatment of hyperproliferative disorders |
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| EP2920181B1 (en) | 2012-11-16 | 2019-01-09 | University Health Network | Pyrazolopyrimidine compounds |
-
2013
- 2013-11-15 EP EP13855919.0A patent/EP2920181B1/en active Active
- 2013-11-15 JP JP2015542121A patent/JP6377068B2/ja active Active
- 2013-11-15 AU AU2013344716A patent/AU2013344716B2/en active Active
- 2013-11-15 NZ NZ707432A patent/NZ707432A/en unknown
- 2013-11-15 WO PCT/CA2013/000957 patent/WO2014075168A1/en not_active Ceased
- 2013-11-15 US US14/443,072 patent/US9573954B2/en active Active
- 2013-11-15 CA CA2889919A patent/CA2889919C/en active Active
-
2014
- 2014-11-14 BR BR112016010080-8A patent/BR112016010080B1/pt active IP Right Grant
- 2014-11-14 EP EP14861448.0A patent/EP3068786B1/en active Active
- 2014-11-14 TW TW103139540A patent/TWI679201B/zh active
- 2014-11-14 DK DK14861448.0T patent/DK3068786T3/en active
- 2014-11-14 HR HRP20181041TT patent/HRP20181041T1/hr unknown
- 2014-11-14 MX MX2016006336A patent/MX373713B/es active IP Right Grant
- 2014-11-14 SG SG11201603102TA patent/SG11201603102TA/en unknown
- 2014-11-14 RS RS20180775A patent/RS57481B1/sr unknown
- 2014-11-14 SI SI201430815T patent/SI3068786T1/sl unknown
- 2014-11-14 ES ES14861448.0T patent/ES2686097T3/es active Active
- 2014-11-14 HU HUE14861448A patent/HUE039351T2/hu unknown
- 2014-11-14 PL PL14861448T patent/PL3068786T3/pl unknown
- 2014-11-14 LT LTEP14861448.0T patent/LT3068786T/lt unknown
- 2014-11-14 PT PT148614480T patent/PT3068786T/pt unknown
- 2014-11-14 WO PCT/CA2014/051091 patent/WO2015070349A1/en not_active Ceased
- 2014-11-14 ME MEP-2018-171A patent/ME03093B/me unknown
- 2014-11-14 CN CN201480062623.XA patent/CN105793261B/zh active Active
-
2015
- 2015-10-29 US US14/926,977 patent/US9657025B2/en active Active
-
2016
- 2016-04-18 IL IL245187A patent/IL245187B/en active IP Right Grant
-
2017
- 2017-02-16 US US15/434,275 patent/US10106545B2/en active Active
- 2017-05-18 US US15/598,402 patent/US10167289B2/en active Active
-
2018
- 2018-07-30 CY CY20181100786T patent/CY1120480T1/el unknown
- 2018-10-09 US US16/155,846 patent/US10570143B2/en active Active
- 2018-12-19 US US16/225,970 patent/US20190322669A1/en not_active Abandoned
-
2020
- 2020-05-21 US US16/880,192 patent/US20210009595A1/en not_active Abandoned
-
2021
- 2021-11-08 US US17/521,255 patent/US20220204511A1/en not_active Abandoned
-
2023
- 2023-12-20 US US18/391,047 patent/US20240287077A1/en not_active Abandoned
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