PL3068786T3 - Związki pirazolopirymidynowe - Google Patents
Związki pirazolopirymidynoweInfo
- Publication number
- PL3068786T3 PL3068786T3 PL14861448T PL14861448T PL3068786T3 PL 3068786 T3 PL3068786 T3 PL 3068786T3 PL 14861448 T PL14861448 T PL 14861448T PL 14861448 T PL14861448 T PL 14861448T PL 3068786 T3 PL3068786 T3 PL 3068786T3
- Authority
- PL
- Poland
- Prior art keywords
- pyrazolopyrimidine compounds
- pyrazolopyrimidine
- compounds
- Prior art date
Links
- OGEBRHQLRGFBNV-RZDIXWSQSA-N chembl2036808 Chemical class C12=NC(NCCCC)=NC=C2C(C=2C=CC(F)=CC=2)=NN1C[C@H]1CC[C@H](N)CC1 OGEBRHQLRGFBNV-RZDIXWSQSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261727581P | 2012-11-16 | 2012-11-16 | |
| US201361808152P | 2013-04-03 | 2013-04-03 | |
| PCT/CA2013/000957 WO2014075168A1 (en) | 2012-11-16 | 2013-11-15 | Pyrazolopyrimidine compounds |
| EP14861448.0A EP3068786B1 (en) | 2012-11-16 | 2014-11-14 | Pyrazolopyrimidine compounds |
| PCT/CA2014/051091 WO2015070349A1 (en) | 2012-11-16 | 2014-11-14 | Pyrazolopyrimidine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3068786T3 true PL3068786T3 (pl) | 2018-10-31 |
Family
ID=50730425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14861448T PL3068786T3 (pl) | 2012-11-16 | 2014-11-14 | Związki pirazolopirymidynowe |
Country Status (24)
| Country | Link |
|---|---|
| US (9) | US9573954B2 (pl) |
| EP (2) | EP2920181B1 (pl) |
| JP (1) | JP6377068B2 (pl) |
| CN (1) | CN105793261B (pl) |
| AU (1) | AU2013344716B2 (pl) |
| BR (1) | BR112016010080B1 (pl) |
| CA (1) | CA2889919C (pl) |
| CY (1) | CY1120480T1 (pl) |
| DK (1) | DK3068786T3 (pl) |
| ES (1) | ES2686097T3 (pl) |
| HR (1) | HRP20181041T1 (pl) |
| HU (1) | HUE039351T2 (pl) |
| IL (1) | IL245187B (pl) |
| LT (1) | LT3068786T (pl) |
| ME (1) | ME03093B (pl) |
| MX (1) | MX373713B (pl) |
| NZ (1) | NZ707432A (pl) |
| PL (1) | PL3068786T3 (pl) |
| PT (1) | PT3068786T (pl) |
| RS (1) | RS57481B1 (pl) |
| SG (1) | SG11201603102TA (pl) |
| SI (1) | SI3068786T1 (pl) |
| TW (1) | TWI679201B (pl) |
| WO (2) | WO2014075168A1 (pl) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013344716B2 (en) | 2012-11-16 | 2018-03-01 | University Health Network | Pyrazolopyrimidine compounds |
| JP6095857B2 (ja) * | 2013-11-15 | 2017-03-15 | ユニバーシティ・ヘルス・ネットワーク | ピラゾロピリミジン化合物 |
| EP3191095A2 (en) * | 2014-09-08 | 2017-07-19 | Dana Farber Cancer Institute, Inc. | Methods of treating cancer comprising administering a ppar-gamma agonist |
| ES2958391T3 (es) | 2014-11-06 | 2024-02-08 | Bial R&D Invest S A | Imidazo[1,5-a]pirimidinas sustituidas y su uso en el tratamiento de trastornos médicos |
| DK3215511T3 (da) | 2014-11-06 | 2024-05-13 | Bial R&D Invest S A | Substituerede pyrazolo(1,5-a)pyrimidiner og deres anvendelse i behandlingen af medicinske lidelser |
| CA2966581A1 (en) | 2014-11-06 | 2016-05-12 | Lysosomal Therapeutics Inc. | Substituted pyrrolo[1,2-a]pyrimidines and their use in the treatment of medical disorders |
| RU2712196C2 (ru) * | 2015-06-24 | 2020-01-24 | Куровир Аб | Производные пиразоло[1,5-a]триазин-4-амина, применимые в терапии |
| WO2017176962A1 (en) | 2016-04-06 | 2017-10-12 | Lysosomal Therapeutics, Inc. | Pyrrolo[1,2-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders |
| WO2017176960A1 (en) | 2016-04-06 | 2017-10-12 | Lysosomal Therapeutics Inc. | Pyrazolo[1,5-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders |
| JP7046827B2 (ja) | 2016-04-06 | 2022-04-04 | リソソーマル・セラピューティクス・インコーポレイテッド | イミダゾ［１，５－ａ］ピリミジニルカルボキサミド化合物および医学的障害の処置におけるその使用 |
| BR112018072552A8 (pt) | 2016-05-05 | 2023-03-14 | Lysosomal Therapeutics Inc | Compostos de imidazo [1,2-b]piridazinas e imidazo [1,5-b] piridazinas substituídas, composição farmacêutica que os compreende e seu uso no tratamento de distúrbios médicos |
| US11345698B2 (en) | 2016-05-05 | 2022-05-31 | Bial—R&D Investments, S.A. | Substituted imidazo[1,2-a]pyridines, substituted imidazo[1,2-a]pyrazines, related compounds, and their use in the treatment of medical disorders |
| CN109476667B (zh) * | 2016-07-18 | 2022-06-28 | 大学健康网络 | Ttk抑制剂的固体形式 |
| US11046698B2 (en) | 2017-07-28 | 2021-06-29 | Nimbus Lakshmi, Inc. | TYK2 inhibitors and uses thereof |
| WO2019023786A1 (en) * | 2017-08-01 | 2019-02-07 | University Health Network | COMBINED THERAPIES FOR THE INHIBITION OF TTK PROTEIN KINASE |
| AU2019273871A1 (en) * | 2018-05-23 | 2020-12-10 | University Health Network | Methods of treating cancers characterized by a high expression level of spindle and kinetochore associated complex subunit 3 (SKA3) gene |
| AU2019370200B2 (en) | 2018-10-30 | 2024-12-19 | Kronos Bio, Inc. | Compounds, compositions, and methods for modulating CDK9 activity |
| CN111377925B (zh) * | 2018-12-28 | 2024-03-12 | 四川科伦博泰生物医药股份有限公司 | 嘌呤类衍生物、其制备方法及其在医药上的应用 |
| CN112142744A (zh) * | 2019-06-28 | 2020-12-29 | 上海瑛派药业有限公司 | 取代的稠合杂芳双环化合物作为激酶抑制剂及其应用 |
| TW202146416A (zh) * | 2019-12-11 | 2021-12-16 | 德商拜耳廠股份有限公司 | 吡唑并三𠯤 |
| CN113773324B (zh) * | 2021-09-07 | 2022-07-26 | 武汉九州钰民医药科技有限公司 | 抗肿瘤药cfi-402257的合成制备工艺 |
| CN116396298A (zh) * | 2023-06-06 | 2023-07-07 | 四川维亚本苑生物科技有限公司 | CDK Ligand-1的中间体XII及CDK Ligand-1的制备方法 |
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| PL354982A1 (pl) | 1999-09-30 | 2004-03-22 | Neurogen Corporation | Amino podstawione pirazolo[1,5-a]-1,5-pirymidyny i pirazolo[1,5-a]-1,3,5-triazyny |
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| AU2013344716B2 (en) | 2012-11-16 | 2018-03-01 | University Health Network | Pyrazolopyrimidine compounds |
-
2013
- 2013-11-15 AU AU2013344716A patent/AU2013344716B2/en active Active
- 2013-11-15 JP JP2015542121A patent/JP6377068B2/ja active Active
- 2013-11-15 CA CA2889919A patent/CA2889919C/en active Active
- 2013-11-15 WO PCT/CA2013/000957 patent/WO2014075168A1/en not_active Ceased
- 2013-11-15 NZ NZ707432A patent/NZ707432A/en unknown
- 2013-11-15 US US14/443,072 patent/US9573954B2/en active Active
- 2013-11-15 EP EP13855919.0A patent/EP2920181B1/en active Active
-
2014
- 2014-11-14 PT PT148614480T patent/PT3068786T/pt unknown
- 2014-11-14 DK DK14861448.0T patent/DK3068786T3/en active
- 2014-11-14 PL PL14861448T patent/PL3068786T3/pl unknown
- 2014-11-14 ME MEP-2018-171A patent/ME03093B/me unknown
- 2014-11-14 TW TW103139540A patent/TWI679201B/zh active
- 2014-11-14 SI SI201430815T patent/SI3068786T1/sl unknown
- 2014-11-14 MX MX2016006336A patent/MX373713B/es active IP Right Grant
- 2014-11-14 EP EP14861448.0A patent/EP3068786B1/en active Active
- 2014-11-14 WO PCT/CA2014/051091 patent/WO2015070349A1/en not_active Ceased
- 2014-11-14 ES ES14861448.0T patent/ES2686097T3/es active Active
- 2014-11-14 SG SG11201603102TA patent/SG11201603102TA/en unknown
- 2014-11-14 BR BR112016010080-8A patent/BR112016010080B1/pt active IP Right Grant
- 2014-11-14 CN CN201480062623.XA patent/CN105793261B/zh active Active
- 2014-11-14 HU HUE14861448A patent/HUE039351T2/hu unknown
- 2014-11-14 HR HRP20181041TT patent/HRP20181041T1/hr unknown
- 2014-11-14 LT LTEP14861448.0T patent/LT3068786T/lt unknown
- 2014-11-14 RS RS20180775A patent/RS57481B1/sr unknown
-
2015
- 2015-10-29 US US14/926,977 patent/US9657025B2/en active Active
-
2016
- 2016-04-18 IL IL245187A patent/IL245187B/en active IP Right Grant
-
2017
- 2017-02-16 US US15/434,275 patent/US10106545B2/en active Active
- 2017-05-18 US US15/598,402 patent/US10167289B2/en active Active
-
2018
- 2018-07-30 CY CY20181100786T patent/CY1120480T1/el unknown
- 2018-10-09 US US16/155,846 patent/US10570143B2/en active Active
- 2018-12-19 US US16/225,970 patent/US20190322669A1/en not_active Abandoned
-
2020
- 2020-05-21 US US16/880,192 patent/US20210009595A1/en not_active Abandoned
-
2021
- 2021-11-08 US US17/521,255 patent/US20220204511A1/en not_active Abandoned
-
2023
- 2023-12-20 US US18/391,047 patent/US20240287077A1/en not_active Abandoned
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