SI2891666T1 - Protitelesa, ki vežejo s celicami povezan antigen CA 125/O722P, in metoda za njihovo uporabo - Google Patents

Protitelesa, ki vežejo s celicami povezan antigen CA 125/O722P, in metoda za njihovo uporabo

Info

Publication number
SI2891666T1
SI2891666T1 SI200332549T SI200332549T SI2891666T1 SI 2891666 T1 SI2891666 T1 SI 2891666T1 SI 200332549 T SI200332549 T SI 200332549T SI 200332549 T SI200332549 T SI 200332549T SI 2891666 T1 SI2891666 T1 SI 2891666T1
Authority
SI
Slovenia
Prior art keywords
antibodies
methods
bind cell
bind
cell
Prior art date
Application number
SI200332549T
Other languages
English (en)
Inventor
Earl F. Albone
Daniel A. Soltis
Original Assignee
Purdue Pharma L.P.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32110191&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2891666(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Purdue Pharma L.P. filed Critical Purdue Pharma L.P.
Publication of SI2891666T1 publication Critical patent/SI2891666T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • A61K47/6869—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from a cell of the reproductive system: ovaria, uterus, testes, prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
SI200332549T 2002-10-16 2003-10-15 Protitelesa, ki vežejo s celicami povezan antigen CA 125/O722P, in metoda za njihovo uporabo SI2891666T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41882802P 2002-10-16 2002-10-16
US48598603P 2003-07-10 2003-07-10
EP15155786.5A EP2891666B1 (en) 2002-10-16 2003-10-15 Antibodies that bind cell-associated CA 125/O722P and methods of use thereof

Publications (1)

Publication Number Publication Date
SI2891666T1 true SI2891666T1 (sl) 2017-11-30

Family

ID=32110191

Family Applications (3)

Application Number Title Priority Date Filing Date
SI200332549T SI2891666T1 (sl) 2002-10-16 2003-10-15 Protitelesa, ki vežejo s celicami povezan antigen CA 125/O722P, in metoda za njihovo uporabo
SI200332423T SI2301965T1 (sl) 2002-10-16 2003-10-15 Protitelesa, ki vežejo celično- povezan CA 125 / O722P in metode uporabe le-teh
SI200332005T SI1551876T1 (sl) 2002-10-16 2003-10-15 Protitelesa, ki se vežejo na celično povezan CA 125/0722P, in postopki za njihovo uporabo

Family Applications After (2)

Application Number Title Priority Date Filing Date
SI200332423T SI2301965T1 (sl) 2002-10-16 2003-10-15 Protitelesa, ki vežejo celično- povezan CA 125 / O722P in metode uporabe le-teh
SI200332005T SI1551876T1 (sl) 2002-10-16 2003-10-15 Protitelesa, ki se vežejo na celično povezan CA 125/0722P, in postopki za njihovo uporabo

Country Status (29)

Country Link
US (7) US7429382B2 (sl)
EP (5) EP2298806A1 (sl)
JP (3) JP4988201B2 (sl)
KR (2) KR20050083774A (sl)
CN (1) CN101812134A (sl)
AR (2) AR041650A1 (sl)
AT (1) ATE502051T1 (sl)
AU (1) AU2003294232A1 (sl)
BR (1) BR0315270A (sl)
CA (1) CA2502367C (sl)
CL (1) CL2010001209A1 (sl)
CY (2) CY1111966T1 (sl)
DE (1) DE60336406D1 (sl)
DK (3) DK2891666T3 (sl)
EA (1) EA011504B1 (sl)
ES (3) ES2363221T3 (sl)
HK (3) HK1086283A1 (sl)
HU (1) HUE034378T2 (sl)
IL (1) IL168058A (sl)
LT (1) LT2891666T (sl)
MX (1) MXPA05003884A (sl)
MY (1) MY139767A (sl)
NO (1) NO20052395L (sl)
NZ (1) NZ563328A (sl)
PT (3) PT2891666T (sl)
RS (1) RS20050300A (sl)
SI (3) SI2891666T1 (sl)
UY (1) UY28028A1 (sl)
WO (1) WO2004035537A2 (sl)

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KR20050083774A (ko) 2005-08-26
JP4988201B2 (ja) 2012-08-01
EP1551876A2 (en) 2005-07-13
US20050064518A1 (en) 2005-03-24
ES2641525T3 (es) 2017-11-10
CA2502367C (en) 2013-12-10
RS20050300A (en) 2007-08-03
US20180105601A1 (en) 2018-04-19
DE60336406D1 (de) 2011-04-28
ES2363221T3 (es) 2011-07-27
US20120149892A1 (en) 2012-06-14

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