SI2158316T1 - Genska ekspresija in bolečina - Google Patents

Genska ekspresija in bolečina

Info

Publication number
SI2158316T1
SI2158316T1 SI200831461T SI200831461T SI2158316T1 SI 2158316 T1 SI2158316 T1 SI 2158316T1 SI 200831461 T SI200831461 T SI 200831461T SI 200831461 T SI200831461 T SI 200831461T SI 2158316 T1 SI2158316 T1 SI 2158316T1
Authority
SI
Slovenia
Prior art keywords
pain
gene expression
gene
expression
Prior art date
Application number
SI200831461T
Other languages
English (en)
Slovenian (sl)
Inventor
Julien Mamet
Original Assignee
Adynxx Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adynxx Inc. filed Critical Adynxx Inc.
Publication of SI2158316T1 publication Critical patent/SI2158316T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/13—Decoys
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
SI200831461T 2007-05-11 2008-05-12 Genska ekspresija in bolečina SI2158316T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91758307P 2007-05-11 2007-05-11
PCT/US2008/063471 WO2008141308A2 (en) 2007-05-11 2008-05-12 Gene expression and pain
EP08755344.2A EP2158316B1 (en) 2007-05-11 2008-05-12 Gene expression and pain

Publications (1)

Publication Number Publication Date
SI2158316T1 true SI2158316T1 (sl) 2015-08-31

Family

ID=40002879

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200831461T SI2158316T1 (sl) 2007-05-11 2008-05-12 Genska ekspresija in bolečina

Country Status (13)

Country Link
US (5) US7943591B2 (enExample)
EP (3) EP3199635B1 (enExample)
JP (5) JP5646320B2 (enExample)
AU (1) AU2008251320B2 (enExample)
CA (1) CA2723672C (enExample)
DK (1) DK2158316T3 (enExample)
ES (2) ES2542511T3 (enExample)
HR (1) HRP20150759T1 (enExample)
HU (1) HUE025701T2 (enExample)
PL (1) PL2158316T3 (enExample)
PT (1) PT2158316E (enExample)
SI (1) SI2158316T1 (enExample)
WO (1) WO2008141308A2 (enExample)

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US8609617B2 (en) 2009-09-04 2013-12-17 University Of Miami KLF family members regulate intrinsic axon regeneration ability
DK2620428T3 (da) 2010-09-24 2019-07-01 Wave Life Sciences Ltd Asymmetrisk hjælpegruppe
US9605019B2 (en) 2011-07-19 2017-03-28 Wave Life Sciences Ltd. Methods for the synthesis of functionalized nucleic acids
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CN104487096B (zh) * 2012-05-10 2020-09-15 埃迪恩克斯股份有限公司 用于活性成分递送的配制物
DK2872485T3 (da) 2012-07-13 2021-03-08 Wave Life Sciences Ltd Asymmetrisk hjælpegruppe
CN112007045B (zh) 2012-07-13 2026-01-06 波涛生命科学有限公司 手性控制
JP6246121B2 (ja) 2012-07-13 2017-12-13 株式会社新日本科学 キラル核酸アジュバント
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EP3095461A4 (en) 2014-01-15 2017-08-23 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having immunity induction activity, and immunity induction activator
US10322173B2 (en) 2014-01-15 2019-06-18 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent
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US20200017853A1 (en) * 2016-02-29 2020-01-16 Adynxx, Inc. Compositions and methods for pain amelioration via modification of gene expression
US20260078376A1 (en) * 2022-08-26 2026-03-19 Core Biotherapeutics, Inc. Oligonucleotides for the treatment of breast cancer

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Also Published As

Publication number Publication date
US8093225B2 (en) 2012-01-10
JP5646320B2 (ja) 2014-12-24
WO2008141308A2 (en) 2008-11-20
EP2818550B1 (en) 2016-12-28
HK1205530A1 (en) 2015-12-18
JP6082796B2 (ja) 2017-02-15
ES2619314T3 (es) 2017-06-26
EP2818550A1 (en) 2014-12-31
JP2017148074A (ja) 2017-08-31
US20120232131A1 (en) 2012-09-13
HUE025701T2 (en) 2016-04-28
EP2158316B1 (en) 2015-04-15
JP2010526541A (ja) 2010-08-05
US8741864B2 (en) 2014-06-03
DK2158316T3 (en) 2015-07-20
WO2008141308A3 (en) 2009-03-05
US20110166212A1 (en) 2011-07-07
JP5890869B2 (ja) 2016-03-22
US9290762B2 (en) 2016-03-22
AU2008251320A1 (en) 2008-11-20
JP2014198053A (ja) 2014-10-23
US20140343132A1 (en) 2014-11-20
AU2008251320B2 (en) 2013-12-19
ES2542511T3 (es) 2015-08-06
HRP20150759T1 (hr) 2015-08-14
US20080300209A1 (en) 2008-12-04
EP3199635B1 (en) 2019-02-06
US7943591B2 (en) 2011-05-17
EP2158316A4 (en) 2011-11-09
CA2723672C (en) 2019-09-03
CA2723672A1 (en) 2008-11-20
EP2158316A2 (en) 2010-03-03
US10041069B2 (en) 2018-08-07
PT2158316E (pt) 2015-07-20
JP6306075B2 (ja) 2018-04-04
JP2016117775A (ja) 2016-06-30
PL2158316T3 (pl) 2015-10-30
US20160222382A1 (en) 2016-08-04
EP3199635A1 (en) 2017-08-02
JP2016014070A (ja) 2016-01-28

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