SI1165126T1 - Postopek priprave cepiva proti humanemu papilomavirusu z razdruzenimi in ponovno zdruzenimi virusu podobnimi delci - Google Patents

Postopek priprave cepiva proti humanemu papilomavirusu z razdruzenimi in ponovno zdruzenimi virusu podobnimi delci

Info

Publication number
SI1165126T1
SI1165126T1 SI200030893T SI200030893T SI1165126T1 SI 1165126 T1 SI1165126 T1 SI 1165126T1 SI 200030893 T SI200030893 T SI 200030893T SI 200030893 T SI200030893 T SI 200030893T SI 1165126 T1 SI1165126 T1 SI 1165126T1
Authority
SI
Slovenia
Prior art keywords
disassembled
preparing
particles
human papillomavirus
papillomavirus vaccine
Prior art date
Application number
SI200030893T
Other languages
English (en)
Inventor
David B Volkin
Henryk Mach
Li Shi
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26824774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1165126(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SI1165126T1 publication Critical patent/SI1165126T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20023—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SI200030893T 1999-03-26 2000-03-22 Postopek priprave cepiva proti humanemu papilomavirusu z razdruzenimi in ponovno zdruzenimi virusu podobnimi delci SI1165126T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12652899P 1999-03-26 1999-03-26
US09/524,624 US6245568B1 (en) 1999-03-26 2000-03-13 Human papilloma virus vaccine with disassembled and reassembled virus-like particles
EP00918248A EP1165126B1 (en) 1999-03-26 2000-03-22 Process for preparing a human papillomavirus vaccine with disassembled and reassembled virus-like particles
PCT/US2000/007595 WO2000057906A1 (en) 1999-03-26 2000-03-22 Human papillomavirus vaccine with disassembled and reassembled virus-like particles

Publications (1)

Publication Number Publication Date
SI1165126T1 true SI1165126T1 (sl) 2006-12-31

Family

ID=26824774

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030893T SI1165126T1 (sl) 1999-03-26 2000-03-22 Postopek priprave cepiva proti humanemu papilomavirusu z razdruzenimi in ponovno zdruzenimi virusu podobnimi delci

Country Status (19)

Country Link
US (2) US6245568B1 (sl)
EP (1) EP1165126B1 (sl)
JP (1) JP4594534B2 (sl)
KR (1) KR20020013516A (sl)
AR (1) AR023166A1 (sl)
AT (1) ATE339222T1 (sl)
AU (1) AU778937B2 (sl)
CA (1) CA2368391C (sl)
CY (4) CY1105779T1 (sl)
DE (4) DE60030698T2 (sl)
DK (1) DK1165126T3 (sl)
ES (1) ES2270822T3 (sl)
FR (1) FR07C0026I2 (sl)
LT (1) LTC1165126I2 (sl)
LU (3) LU91326I2 (sl)
NL (3) NL300268I1 (sl)
PT (1) PT1165126E (sl)
SI (1) SI1165126T1 (sl)
WO (1) WO2000057906A1 (sl)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7351533B2 (en) 1997-09-05 2008-04-01 Medimmune, Inc. In vitro method for disassmbly/reassembly of papillomavirus virus-like particles (VLPs). Homogeneous VLP and cavsomere compositions produced by said methods: use thereof as vehicle for improved purification, and delivery of active agents
US6962777B1 (en) * 1997-09-05 2005-11-08 Medimmune, Inc. In vitro method for disassembly/reassembly of papillomavirus virus-like particles (vlps), homogeneous vlp and capsomere compositions produced by said methods; use thereof as vehicle for improved purification, and delivery of active agents
ES2325053T3 (es) * 1999-12-09 2009-08-25 Medimmune, Llc Metodo in vitro para desensamblaje/reensamblaje de particulas similares a virus de papilomavirus (vlp).
EP1409013B1 (en) * 2001-07-26 2009-11-18 Novartis Vaccines and Diagnostics S.r.l. Vaccines comprising aluminium adjuvants and histidine
GB0118249D0 (en) 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
DE10137102A1 (de) * 2001-07-30 2003-02-27 Deutsches Krebsforsch Polyvalente Vakzine gegen durch Papillomaviren verursachte Erkrankungen, Verfahren zu deren Herstellung und deren Verwendung
US20060073530A1 (en) * 2001-08-15 2006-04-06 Olaf Schneewind Methods and compositions involving sortase B
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
AU2003217413A1 (en) * 2002-02-14 2003-09-04 Novavax, Inc. Method for isolation and purification of expressed gene products in vitro
GB0206360D0 (en) * 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
GB0206359D0 (en) * 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
DE10237639A1 (de) * 2002-08-13 2004-02-26 Martin-Luther-Universität Halle-Wittenberg Verfahren zur Herstellung von virusanalogen Partikeln durch in vitro-Assemblierung von Kapsomeren oder von Kapsomeren, an die biologisch aktive Makromoleküle gebunden sind, bei gleichzeitiger Verpackung der Makromoleküle
GB0220194D0 (en) * 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
KR101130948B1 (ko) 2002-11-01 2012-03-30 글락소스미스클라인 바이오로지칼즈 에스.에이. 건조 공정
US7858098B2 (en) * 2002-12-20 2010-12-28 Glaxosmithkline Biologicals, S.A. Vaccine
NZ540811A (en) 2002-12-20 2007-03-30 Glaxosmithkline Biolog S Use of HPV 16 and HPV 18 VLPs in the prevention of infection or disease caused by one or more of the group of oncogenic HPV types excluding types 16 and 18
JP4734608B2 (ja) * 2004-07-01 2011-07-27 国立大学法人東京工業大学 生理的条件下でのウイルス粒子様構造体及びその形成方法
US7906024B2 (en) * 2005-01-25 2011-03-15 Wyeth Research Ireland Limited Shear protectants in harvest microfiltration
JP2009501520A (ja) * 2005-07-14 2009-01-22 メイヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ パラミクソウイルス科ウイルス調製物
US20090105130A1 (en) * 2005-08-12 2009-04-23 Astellas Pharma Inc. Depsipeptide-containing injection solution
CN101291689B (zh) * 2005-09-01 2012-12-05 若泽·路易斯·努诺·阿雅拉 用于大规模接种系统的活抗原的疫苗稳定化制剂
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
CA2652118C (en) * 2006-05-11 2015-07-07 Becton, Dickinson And Company Method of protein extraction from cells
US9207240B2 (en) * 2007-11-14 2015-12-08 Arbor Vita Corporation Method of efficient extraction of protein from cells
US8420128B2 (en) * 2008-03-31 2013-04-16 Morinaga Milk Industry Co., Ltd. Method of imparting heat resistance to lactoferrin
JP5916610B2 (ja) 2009-09-03 2016-05-11 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 直接的な化学的溶解のための方法および組成物
EP3831406B1 (en) 2010-08-23 2024-06-05 Wyeth LLC Stable formulations of neisseria meningitidis rlp2086 antigens
AU2011300409B2 (en) 2010-09-10 2015-03-26 Wyeth Llc Non-lipidated variants of Neisseria meningitidis ORF2086 antigens
MX351993B (es) 2012-03-09 2017-11-03 Pfizer Composiciones de neisseria meningitidis y metodos de las mismas.
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
CN104203270A (zh) 2012-03-18 2014-12-10 葛兰素史密丝克莱恩生物有限公司 针对人乳头状瘤病毒的接种方法
KR101559622B1 (ko) * 2012-07-30 2015-10-13 중앙대학교 산학협력단 인유두종바이러스 바이러스 유사입자의 고효율 정제방법
CA2903716C (en) 2013-03-08 2019-04-09 Pfizer Inc. Immunogenic fusion polypeptides
MX369534B (es) 2013-09-08 2019-11-11 Pfizer Composiciones de neisseria meningitidis y sus metodos.
RU2723045C2 (ru) 2015-02-19 2020-06-08 Пфайзер Инк. Композиции neisseria meningitidis и способы их получения
JP7010961B2 (ja) 2017-01-31 2022-02-10 ファイザー・インク 髄膜炎菌組成物およびその方法
US20200010850A1 (en) 2017-02-17 2020-01-09 The USA, as represeented by the Secretary, Dept. of Health and Human Services Efficient cell free production of papillomavirus gene transfer vectors
CN110987571A (zh) * 2019-12-31 2020-04-10 广州金域医学检验中心有限公司 一种单克隆多聚体m蛋白解聚方法
CN111812313B (zh) * 2020-06-22 2021-10-08 北京生物制品研究所有限责任公司 铝佐剂吸附型新型冠状病毒灭活疫苗中抗原的解离方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0971696B1 (en) * 1997-02-06 2010-06-09 Merck Sharp & Dohme Corp. Thimerosal-free preservatives for vaccines
WO1998044944A2 (en) 1997-04-08 1998-10-15 Merck & Co., Inc. Stabilized human papillomavirus formulations
JP2002510976A (ja) 1997-07-03 2002-04-09 ユニバーシティ・オブ・コロラド・ユニバーシティ・テクノロジー・コーポレイション 均質のヒト・パピローマウイルスのカプソメアを含有する組成物、その製造方法、およびその診断的、予防的、治療的使用

Also Published As

Publication number Publication date
LU91328I2 (fr) 2007-05-14
CY1105779T1 (el) 2010-07-28
ES2270822T3 (es) 2007-04-16
LTC1165126I2 (lt) 2020-04-27
ATE339222T1 (de) 2006-10-15
DE60030698D1 (de) 2006-10-26
LU91326I2 (fr) 2007-05-14
LU91326I9 (sl) 2018-12-31
EP1165126B1 (en) 2006-09-13
CY2007008I2 (el) 2009-11-04
AR023166A1 (es) 2002-09-04
DK1165126T3 (da) 2007-01-08
CY2007010I1 (el) 2009-11-04
CY2007010I2 (el) 2009-11-04
DE122007000032I1 (de) 2007-08-09
AU778937B2 (en) 2004-12-23
LU91327I2 (fr) 2007-05-14
NL300270I1 (nl) 2007-05-01
LTPA2007002I1 (lt) 2020-03-25
CY2007008I1 (el) 2009-11-04
FR07C0026I1 (sl) 2007-04-27
NL300269I2 (nl) 2008-07-01
CA2368391A1 (en) 2000-10-05
US6245568B1 (en) 2001-06-12
CY2007009I1 (el) 2010-07-28
NL300268I1 (nl) 2007-05-01
CY2007009I2 (el) 2010-07-28
LU91328I9 (sl) 2019-03-01
CA2368391C (en) 2011-06-07
WO2000057906A1 (en) 2000-10-05
FR07C0026I2 (fr) 2012-08-03
DE122007000034I1 (de) 2007-08-09
DE60030698T2 (de) 2007-07-19
US20010021385A1 (en) 2001-09-13
JP2002540167A (ja) 2002-11-26
PT1165126E (pt) 2006-12-29
JP4594534B2 (ja) 2010-12-08
DE122007000033I1 (de) 2007-08-09
EP1165126A1 (en) 2002-01-02
KR20020013516A (ko) 2002-02-20
AU3909300A (en) 2000-10-16
NL300269I1 (nl) 2007-05-01
LU91327I9 (sl) 2019-03-01

Similar Documents

Publication Publication Date Title
SI1165126T1 (sl) Postopek priprave cepiva proti humanemu papilomavirusu z razdruzenimi in ponovno zdruzenimi virusu podobnimi delci
AU2001236042A1 (en) Cell usable in serum-free culture and suspension culture and process for producing virus for vaccine by using the cell
IL158107A0 (en) Human papillomaviruses vaccine
HK1048436A1 (en) Vaccine against hbv and hpv
IL153167A0 (en) Phenyl derivatives, a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy
HUP0103091A3 (en) Process for purifying human papillomavirus virus-like particles
SI1150712T1 (sl) Pripravek cepiva proti humanem papiloma virusu
AU2003227533A1 (en) Virus like particle from papillomavirus and their use in vaccine
AU4121301A (en) Persimmon vinegar powder and process for preparing the same
AU2003271021A1 (en) Immunogen for preparation of therapeutic vaccines or drugs for treatment of hepatitis b and the producing method and use thereof
IL162381A0 (en) A recombinant dna construct and a process for the preparation of a non-toxic anthrax vaccine
AU4316299A (en) Oral immunization with papillomavirus virus-like particles
AU2003278175A8 (en) Vaccines of enhanced immunogenicity, and methods for preparing such vaccines
HUP0202770A3 (en) Human papilloma virus vaccine
AU2322300A (en) Carbon-based heating unit and method for preparation thereof
AU2992901A (en) Method for preparing and administering medicinal plant material
AU2003298984A1 (en) Method of preparing a vaccine and anti-tumor vaccines
AU2001285817A1 (en) Koji molds and use thereof for preparing cholesterol-lowering products
HUP0203468A3 (en) Betha-d-5-thioxylose derivatives, preparation method and therapeutic use thereof
AU2001269640A1 (en) Vaccine against the influenza virus and method for producing said virus vaccine
AU6964001A (en) Vaccine against the influenza virus and method for producing said virus vaccine
AU2002223398A1 (en) A vaccine for influenza virus and its preparation
AU2002213755A1 (en) A vaccine for acids and its preparation and use
EP1144002A3 (en) A method for selecting and producing vaccine and diagnostic preparations
SI1210112T1 (sl) Cepivo proti HBV in HPV