DE122007000033I1 - Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und ReassembliertenVirusaehnlichen Partikeln - Google Patents

Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und ReassembliertenVirusaehnlichen Partikeln

Info

Publication number
DE122007000033I1
DE122007000033I1 DE200712000033 DE122007000033C DE122007000033I1 DE 122007000033 I1 DE122007000033 I1 DE 122007000033I1 DE 200712000033 DE200712000033 DE 200712000033 DE 122007000033 C DE122007000033 C DE 122007000033C DE 122007000033 I1 DE122007000033 I1 DE 122007000033I1
Authority
DE
Germany
Prior art keywords
disassembled
particles
producing
human papillomavirus
papillomavirus vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE200712000033
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26824774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE122007000033(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE122007000033I1 publication Critical patent/DE122007000033I1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20023—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE200712000033 1999-03-26 2000-03-22 Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und ReassembliertenVirusaehnlichen Partikeln Pending DE122007000033I1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12652899P 1999-03-26 1999-03-26
US09/524,624 US6245568B1 (en) 1999-03-26 2000-03-13 Human papilloma virus vaccine with disassembled and reassembled virus-like particles
PCT/US2000/007595 WO2000057906A1 (en) 1999-03-26 2000-03-22 Human papillomavirus vaccine with disassembled and reassembled virus-like particles

Publications (1)

Publication Number Publication Date
DE122007000033I1 true DE122007000033I1 (de) 2007-08-09

Family

ID=26824774

Family Applications (4)

Application Number Title Priority Date Filing Date
DE200712000034 Pending DE122007000034I1 (de) 1999-03-26 2000-03-22 Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und ReassembliertenVirusaehnlichen Partikeln
DE200712000033 Pending DE122007000033I1 (de) 1999-03-26 2000-03-22 Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und ReassembliertenVirusaehnlichen Partikeln
DE200712000032 Pending DE122007000032I1 (de) 1999-03-26 2000-03-22 Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und Reassembliertenn Virusaehnlichen Partikeln
DE60030698T Expired - Lifetime DE60030698T2 (de) 1999-03-26 2000-03-22 Verfahren zur herstellung eines human-papillomavirus-vakzins mit disassemblierten und reassemblierten virus-aehnlichen partikeln

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE200712000034 Pending DE122007000034I1 (de) 1999-03-26 2000-03-22 Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und ReassembliertenVirusaehnlichen Partikeln

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE200712000032 Pending DE122007000032I1 (de) 1999-03-26 2000-03-22 Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und Reassembliertenn Virusaehnlichen Partikeln
DE60030698T Expired - Lifetime DE60030698T2 (de) 1999-03-26 2000-03-22 Verfahren zur herstellung eines human-papillomavirus-vakzins mit disassemblierten und reassemblierten virus-aehnlichen partikeln

Country Status (19)

Country Link
US (2) US6245568B1 (de)
EP (1) EP1165126B1 (de)
JP (1) JP4594534B2 (de)
KR (1) KR20020013516A (de)
AR (1) AR023166A1 (de)
AT (1) ATE339222T1 (de)
AU (1) AU778937B2 (de)
CA (1) CA2368391C (de)
CY (4) CY1105779T1 (de)
DE (4) DE122007000034I1 (de)
DK (1) DK1165126T3 (de)
ES (1) ES2270822T3 (de)
FR (1) FR07C0026I2 (de)
LT (1) LTC1165126I2 (de)
LU (3) LU91326I2 (de)
NL (3) NL300270I1 (de)
PT (1) PT1165126E (de)
SI (1) SI1165126T1 (de)
WO (1) WO2000057906A1 (de)

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US7351533B2 (en) 1997-09-05 2008-04-01 Medimmune, Inc. In vitro method for disassmbly/reassembly of papillomavirus virus-like particles (VLPs). Homogeneous VLP and cavsomere compositions produced by said methods: use thereof as vehicle for improved purification, and delivery of active agents
ATE426803T1 (de) * 1999-12-09 2009-04-15 Medimmune Inc In-vitro-methode zur zerlegung und zum wiederzusammenfugen von papillomavirusartigen partikeln
GB0118249D0 (en) 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
CN100350972C (zh) * 2001-07-26 2007-11-28 启龙股份公司 含有铝佐剂和组氨酸的疫苗
DE10137102A1 (de) * 2001-07-30 2003-02-27 Deutsches Krebsforsch Polyvalente Vakzine gegen durch Papillomaviren verursachte Erkrankungen, Verfahren zu deren Herstellung und deren Verwendung
US20060073530A1 (en) * 2001-08-15 2006-04-06 Olaf Schneewind Methods and compositions involving sortase B
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
US20040121465A1 (en) * 2002-02-14 2004-06-24 Novavax, Inc. Optimization of gene sequences of virus-like particles for expression in insect cells
GB0206360D0 (en) 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
GB0206359D0 (en) * 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
DE10237639A1 (de) * 2002-08-13 2004-02-26 Martin-Luther-Universität Halle-Wittenberg Verfahren zur Herstellung von virusanalogen Partikeln durch in vitro-Assemblierung von Kapsomeren oder von Kapsomeren, an die biologisch aktive Makromoleküle gebunden sind, bei gleichzeitiger Verpackung der Makromoleküle
GB0220194D0 (en) * 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
BR0315767A (pt) 2002-11-01 2005-09-06 Glaxosmithkline Biolog Sa Composição imunogência, método para fabricar uma vacina, kit, vacina, recipiente com uma superfìcie interna repelente à água, e, método para preservar uma composição que compreende ipv e um agente estabilizador
EA200701633A1 (ru) 2002-12-20 2007-12-28 Глаксосмитклайн Байолоджикалс С.А. Вакцина на основе вирусоподобных частиц вируса папилломы человека 16 и вируса папилломы человека 18 l1
US7858098B2 (en) * 2002-12-20 2010-12-28 Glaxosmithkline Biologicals, S.A. Vaccine
EP1785433A4 (de) * 2004-07-01 2008-10-01 Tokyo Inst Tech Viruspartikelähnliches konstrukt und verfahren zu dessen bildung unter physiologischen bedingungen
RU2442822C2 (ru) * 2005-01-25 2012-02-20 Вайет Рисерч Айрлэнд Лимитед Вещества, защищающие клетки от рассечения при сборе микрофильтрацией
US7759104B2 (en) * 2005-07-14 2010-07-20 Mayo Foundation For Medical Education And Research Paramyxoviridae virus preparations
WO2007020871A1 (ja) * 2005-08-12 2007-02-22 Astellas Pharma Inc. デプシペプチド含有注射液
BRPI0520505B1 (pt) * 2005-09-01 2015-03-31 José Luis Nuño Ayalá Fórmula estabilizadora de vacinas com antígenos vivos para uso em sistemas de vacinação em massa
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
JP2009536958A (ja) * 2006-05-11 2009-10-22 ベクトン・ディキンソン・アンド・カンパニー 細胞からのタンパク質抽出方法
US9207240B2 (en) 2007-11-14 2015-12-08 Arbor Vita Corporation Method of efficient extraction of protein from cells
US8420128B2 (en) * 2008-03-31 2013-04-16 Morinaga Milk Industry Co., Ltd. Method of imparting heat resistance to lactoferrin
JP5916610B2 (ja) 2009-09-03 2016-05-11 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 直接的な化学的溶解のための方法および組成物
AU2011294776B2 (en) 2010-08-23 2016-02-04 Wyeth Llc Stable formulations of Neisseria meningitidis rLP2086 antigens
CA2809758C (en) 2010-09-10 2021-07-13 Wyeth Llc Non-lipidated variants of neisseria meningitidis orf2086 antigens
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
EP4043029A1 (de) 2012-03-09 2022-08-17 Pfizer Inc. Neisseria meningitidis-zusammensetzungen und verfahren dafür
WO2013139744A1 (en) 2012-03-18 2013-09-26 Glaxosmithkline Biologicals S.A. Method of vaccination against human papillomavirus
KR101559622B1 (ko) * 2012-07-30 2015-10-13 중앙대학교 산학협력단 인유두종바이러스 바이러스 유사입자의 고효율 정제방법
ES2685894T3 (es) 2013-03-08 2018-10-15 Pfizer Inc. Polipéptidos de fusión inmunogénicos
MX369534B (es) 2013-09-08 2019-11-11 Pfizer Composiciones de neisseria meningitidis y sus metodos.
RU2723045C2 (ru) 2015-02-19 2020-06-08 Пфайзер Инк. Композиции neisseria meningitidis и способы их получения
MX2019009011A (es) 2017-01-31 2019-09-26 Pfizer Composiciones de neisseria meningitidis y metodos respectivos.
WO2018152505A1 (en) 2017-02-17 2018-08-23 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Efficient cell free production of papillomavirus gene transfer vectors
CN110987571A (zh) * 2019-12-31 2020-04-10 广州金域医学检验中心有限公司 一种单克隆多聚体m蛋白解聚方法
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Also Published As

Publication number Publication date
EP1165126B1 (de) 2006-09-13
EP1165126A1 (de) 2002-01-02
AR023166A1 (es) 2002-09-04
LU91328I2 (fr) 2007-05-14
NL300269I1 (nl) 2007-05-01
CY2007010I1 (el) 2009-11-04
FR07C0026I1 (de) 2007-04-27
JP4594534B2 (ja) 2010-12-08
US20010021385A1 (en) 2001-09-13
CY2007008I2 (el) 2009-11-04
PT1165126E (pt) 2006-12-29
CY2007009I1 (el) 2010-07-28
DE60030698D1 (de) 2006-10-26
AU3909300A (en) 2000-10-16
FR07C0026I2 (fr) 2012-08-03
CY1105779T1 (el) 2010-07-28
ATE339222T1 (de) 2006-10-15
AU778937B2 (en) 2004-12-23
CY2007010I2 (el) 2009-11-04
DE60030698T2 (de) 2007-07-19
WO2000057906A1 (en) 2000-10-05
LU91326I2 (fr) 2007-05-14
CA2368391A1 (en) 2000-10-05
KR20020013516A (ko) 2002-02-20
DE122007000034I1 (de) 2007-08-09
CY2007009I2 (el) 2010-07-28
ES2270822T3 (es) 2007-04-16
JP2002540167A (ja) 2002-11-26
DK1165126T3 (da) 2007-01-08
NL300268I1 (nl) 2007-05-01
CY2007008I1 (el) 2009-11-04
LU91328I9 (de) 2019-03-01
CA2368391C (en) 2011-06-07
SI1165126T1 (sl) 2006-12-31
NL300269I2 (nl) 2008-07-01
US6245568B1 (en) 2001-06-12
LU91327I2 (fr) 2007-05-14
LTPA2007002I1 (lt) 2020-03-25
LU91327I9 (de) 2019-03-01
DE122007000032I1 (de) 2007-08-09
NL300270I1 (nl) 2007-05-01
LU91326I9 (de) 2018-12-31
LTC1165126I2 (lt) 2020-04-27

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