SI1042319T1 - Dihydrobenzofurans - Google Patents

Dihydrobenzofurans

Info

Publication number
SI1042319T1
SI1042319T1 SI9830628T SI9830628T SI1042319T1 SI 1042319 T1 SI1042319 T1 SI 1042319T1 SI 9830628 T SI9830628 T SI 9830628T SI 9830628 T SI9830628 T SI 9830628T SI 1042319 T1 SI1042319 T1 SI 1042319T1
Authority
SI
Slovenia
Prior art keywords
dihydrobenzofurans
meaningand
heterocycle
meanings
compounds
Prior art date
Application number
SI9830628T
Other languages
English (en)
Slovenian (sl)
Inventor
Ulrich Thibaut
Armin Hatzelmann
Hildegard Boss
Dietrich H�FNER
Rolf Beume
Hans-Peter Kley
Hendrik Timmerman
Der Laan Ivonne Johanna Van
Wolf-R�diger ULRICH
Geert Jan Sterk
Der Mey Margaretha Van
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of SI1042319T1 publication Critical patent/SI1042319T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI9830628T 1997-12-15 1998-12-10 Dihydrobenzofurans SI1042319T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97122039 1997-12-15
EP98966288A EP1042319B1 (en) 1997-12-15 1998-12-10 Dihydrobenzofurans
PCT/EP1998/008054 WO1999031090A1 (en) 1997-12-15 1998-12-10 Dihydrobenzofurans

Publications (1)

Publication Number Publication Date
SI1042319T1 true SI1042319T1 (en) 2004-08-31

Family

ID=8227798

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830628T SI1042319T1 (en) 1997-12-15 1998-12-10 Dihydrobenzofurans

Country Status (17)

Country Link
US (1) US6380196B1 (cs)
EP (1) EP1042319B1 (cs)
JP (1) JP2002508368A (cs)
AT (1) ATE258930T1 (cs)
AU (1) AU753576B2 (cs)
CA (1) CA2314111A1 (cs)
CZ (1) CZ299304B6 (cs)
DE (1) DE69821530T2 (cs)
DK (1) DK1042319T3 (cs)
EE (1) EE04312B1 (cs)
ES (1) ES2216349T3 (cs)
HU (1) HU225114B1 (cs)
IL (1) IL136359A (cs)
PL (1) PL191236B1 (cs)
PT (1) PT1042319E (cs)
SI (1) SI1042319T1 (cs)
WO (1) WO1999031090A1 (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0013478B8 (pt) 1999-08-21 2016-12-27 Altana Pharma Ag medicamento compreendendo inibidor pde e uso de roflumilast
AU7654200A (en) * 1999-09-14 2001-04-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone derivatives as pd3/4 inhibitors
JP2003512466A (ja) * 1999-10-25 2003-04-02 アルタナ ファルマ アクチエンゲゼルシャフト Ｐｄｅ４インヒビターとしてのテトラヒドロチオピランフタラジノン誘導体
CA2388121A1 (en) * 1999-10-25 2001-05-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone derivatives as pde 4 inhibitors
KR20030031907A (ko) * 2000-06-05 2003-04-23 알타나 파마 아게 β-2-아드레날린 수용체 작동물질로서 뿐만 아니라ＰＤＥ4-억제제로서 효과적인 화합물
NZ527424A (en) 2001-02-15 2005-02-25 Altana Pharma Ag Phthalayinone-piperidino-derivatives as PDE4 inhibitors
US7186710B2 (en) 2001-04-25 2007-03-06 Altana Pharma Ag Phthalazinones
EP1385838A1 (en) * 2001-04-25 2004-02-04 ALTANA Pharma AG Piperazino-derivatives and their use as pde4 inhibitor
AU2003219559A1 (en) * 2002-03-29 2003-10-13 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition for preventing or treating respiratory disease
HRP20050197A2 (en) * 2002-08-10 2006-06-30 Altana Pharma Ag Piperidine-n-oxide-derivatives
ES2286491T3 (es) * 2002-08-10 2007-12-01 Nycomed Gmbh Piperidina-ftalazonas sustituidas con pirrolidinadiona, como agentes inhibidores de la pde4.
JP2005538138A (ja) * 2002-08-10 2005-12-15 アルタナ　ファルマ　アクチエンゲゼルシャフト Ｐｄｅ４インヒビターとしてのピリダジノン誘導体
AU2003255376A1 (en) * 2002-08-10 2004-03-11 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
WO2004087211A2 (en) 2003-04-01 2004-10-14 Applied Research Systems Ars Holding N.V. Inhibitors of phosphodiesterases in infertility
EP1716133B1 (en) * 2004-02-04 2008-03-26 Nycomed GmbH 2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors
US20080227790A1 (en) * 2004-02-04 2008-09-18 Altana Pharma Ag Pyridazinone Derivatives and their Use as Pde4 Inhibitors
US7763617B2 (en) * 2005-03-07 2010-07-27 Kyorin Pharmaceutical Co., Ltd. Pyrazolopyridine-4-yl pyridazinone derivatives and addition salts thereof, and PDE inhibitors comprising the same derivatives or salts as active ingredient
WO2007058392A1 (ja) * 2005-11-21 2007-05-24 Japan Tobacco Inc. ヘテロ環化合物およびその医薬用途
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721784A (en) * 1986-12-22 1988-01-26 Ortho Pharmaceutical Corporation 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
JPH04504576A (ja) * 1989-04-17 1992-08-13 ビイク　グルデン　ロンベルク―ヒェーミッシェ　ファブリーク　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング 新規アリールピリダジン、その製造、使用およびこれを含有する医薬品
WO1991012251A1 (fr) 1990-02-19 1991-08-22 Chugai Seiyaku Kabushiki Kaisha Nouveau compose heterocyclique condense et agent anti-asthme prepare a partir de ce compose
ATE168101T1 (de) * 1990-10-16 1998-07-15 Byk Gulden Lomberg Chem Fab Arylpyridazinone
US5449676A (en) * 1991-04-26 1995-09-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Pyridazines
WO1993000903A1 (de) * 1991-07-05 1993-01-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Verwendung substituierter pyridazine gegen dermatosen
MX9205794A (es) * 1991-10-09 1993-04-01 Syntex Inc Compuesto de benzo- y pirido- piridazinona y piridazinotiona
DE4230755A1 (de) * 1992-09-14 1994-03-17 Schering Ag Verwendung von PDE-Inhibitoren bei der Behandlung von Nieren- und Ureter-Erkrankungen
ATE234270T1 (de) * 1992-12-02 2003-03-15 Pfizer Cathecoldiether als selektive pde iv hemmungsmittel
US5476834A (en) * 1993-03-17 1995-12-19 Sumitomo Chemical Company, Limited Dihydrobenzofuran derivatives, their production and use
WO1996003399A1 (de) * 1994-07-22 1996-02-08 Byk Gulden Lomberg Chemische Fabrik Gmbh Dihydrobenzofurane
CN1151136C (zh) 1994-08-09 2004-05-26 卫材株式会社 缩合哒嗪系化合物
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
US5821250A (en) * 1996-02-01 1998-10-13 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents

Also Published As

Publication number Publication date
PL191236B1 (pl) 2006-04-28
EP1042319B1 (en) 2004-02-04
DE69821530T2 (de) 2004-12-23
EE04312B1 (et) 2004-06-15
IL136359A (en) 2003-03-12
CZ20002218A3 (cs) 2000-11-15
EP1042319A1 (en) 2000-10-11
HUP0004561A2 (hu) 2002-03-28
EE200000335A (et) 2001-10-15
IL136359A0 (en) 2001-06-14
HUP0004561A3 (en) 2002-04-29
PL341239A1 (en) 2001-03-26
WO1999031090A1 (en) 1999-06-24
HU225114B1 (en) 2006-06-28
JP2002508368A (ja) 2002-03-19
ES2216349T3 (es) 2004-10-16
AU753576B2 (en) 2002-10-24
CZ299304B6 (cs) 2008-06-11
DE69821530D1 (de) 2004-03-11
DK1042319T3 (da) 2004-06-01
AU2270199A (en) 1999-07-05
ATE258930T1 (de) 2004-02-15
US6380196B1 (en) 2002-04-30
CA2314111A1 (en) 1999-06-24
PT1042319E (pt) 2004-06-30

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