SI0757691T1 - Cefalosporinska sinteza - Google Patents

Cefalosporinska sinteza

Info

Publication number
SI0757691T1
SI0757691T1 SI9530680T SI9530680T SI0757691T1 SI 0757691 T1 SI0757691 T1 SI 0757691T1 SI 9530680 T SI9530680 T SI 9530680T SI 9530680 T SI9530680 T SI 9530680T SI 0757691 T1 SI0757691 T1 SI 0757691T1
Authority
SI
Slovenia
Prior art keywords
denotes
hydrogen
group
silyl group
denote
Prior art date
Application number
SI9530680T
Other languages
English (en)
Inventor
Gerd Ascher
Johannes Ludescher
Hubert Sturm
Josef Wieser
Original Assignee
Sandoz G.M.B.H.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT0085894A external-priority patent/AT402072B/de
Priority claimed from AT85794A external-priority patent/AT402927B/de
Priority claimed from AT0106694A external-priority patent/AT402929B/de
Application filed by Sandoz G.M.B.H. filed Critical Sandoz G.M.B.H.
Publication of SI0757691T1 publication Critical patent/SI0757691T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cephalosporin Compounds (AREA)
SI9530680T 1994-04-25 1995-04-24 Cefalosporinska sinteza SI0757691T1 (sl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AT0085894A AT402072B (de) 1994-04-25 1994-04-25 Cephemderivate und verfahren zu ihrer herstellung
AT85794A AT402927B (de) 1994-04-25 1994-04-25 Neue cefalosporinderivate, verfahren zu ihrer herstellung und ihre verwendung
AT0106694A AT402929B (de) 1994-05-25 1994-05-25 Neue cephalosporinderivate, verfahren zu ihrer herstellung und ihre verwendung
EP95917948A EP0757691B1 (en) 1994-04-25 1995-04-24 Cephalosporin synthesis
PCT/EP1995/001538 WO1995029182A1 (en) 1994-04-25 1995-04-24 Cephalosporin synthesis

Publications (1)

Publication Number Publication Date
SI0757691T1 true SI0757691T1 (sl) 2003-12-31

Family

ID=27146806

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9530680T SI0757691T1 (sl) 1994-04-25 1995-04-24 Cefalosporinska sinteza

Country Status (26)

Country Link
US (4) US5856474A (sl)
EP (2) EP1340762B1 (sl)
JP (1) JP3302369B2 (sl)
KR (1) KR100487833B1 (sl)
CN (3) CN1145629C (sl)
AT (2) ATE244247T1 (sl)
AU (1) AU686380B2 (sl)
BR (1) BR9507512A (sl)
CA (2) CA2533837A1 (sl)
CY (1) CY2494B1 (sl)
CZ (1) CZ297565B6 (sl)
DE (2) DE69531203T2 (sl)
DK (1) DK0757691T3 (sl)
ES (1) ES2202362T3 (sl)
FI (1) FI963761A (sl)
HU (3) HUT75229A (sl)
MX (1) MX9604353A (sl)
NO (1) NO318020B1 (sl)
NZ (2) NZ285084A (sl)
PL (2) PL182864B1 (sl)
PT (1) PT757691E (sl)
RU (2) RU2150471C1 (sl)
SI (1) SI0757691T1 (sl)
SK (1) SK285948B6 (sl)
TW (1) TW427992B (sl)
WO (1) WO1995029182A1 (sl)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248881B1 (en) * 1991-03-08 2001-06-19 Biochemie Gmbh Intermediates and process for the production of 3-vinyl cephalosporins
US5856474A (en) * 1994-04-25 1999-01-05 Biochemie Gesellschaft, M.B.H. Cephalosporin synthesis
ATE370146T1 (de) 1999-07-05 2007-09-15 Basilea Pharmaceutica Ag Verfahren zur herstellung von cephalosporin- derivaten
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
EP2263654B1 (en) 2000-06-21 2012-10-10 Cubist Pharmaceuticals, Inc. Compositions for improving the oral absorption of antimicrobial agents
US7527807B2 (en) * 2000-06-21 2009-05-05 Cubist Pharmaceuticals, Inc. Compositions and methods for increasing the oral absorption of antimicrobials
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
WO2005009368A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
WO2005009365A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
JP2006528185A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8758820B2 (en) 2003-08-11 2014-06-24 Shionogi Inc. Robust pellet
CA2535398C (en) 2003-08-12 2013-11-12 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
AU2004270170B2 (en) 2003-08-29 2011-01-27 Shionogi, Inc. Antibiotic product, use and formulation thereof
CA2538064C (en) 2003-09-15 2013-12-17 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
AU2005269981A1 (en) 2004-07-02 2006-02-09 Bonck, John A Tablet for pulsed delivery
EP1877041A2 (en) * 2005-04-29 2008-01-16 Cubist Pharmaceuticals, Inc. Therapeutic compositions
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
ES2565952T3 (es) * 2009-05-25 2016-04-07 Sandoz Ag Método para la producción de ceftobiprol medocaril
ITMI20131820A1 (it) * 2013-11-04 2015-05-05 Laboratorio Chimico Int Spa Procedimento per la preparazione di olopatadina
CN109180704B (zh) * 2018-11-19 2020-06-05 齐鲁安替制药有限公司 一种头孢妥仑匹酯的合成方法
BR112022004107A2 (pt) 2019-09-06 2022-05-31 Nabriva Therapeutics GmbH Conjugados de cefalosporina de sideróforo e seus usos

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3351596A (en) * 1966-09-21 1967-11-07 Lilly Co Eli 3-formyl cephalosporins
CH556876A (de) * 1971-05-19 1974-12-13 Ciba Geigy Ag Verfahren zur herstellung von cephalosporansaeurederivaten.
CH546794A (de) * 1970-06-18 1974-03-15 Ciba Geigy Ag Verfahren zur herstellung von cephalosporansaeurederivaten.
US3674784A (en) * 1970-07-27 1972-07-04 Lilly Co Eli 3-formyl cephalosporin sulfoxides
GB1368231A (en) * 1970-07-31 1974-09-25 Glaxo Lab Ltd Thio-substituted azetidinones and thiazolino azetidinones
US3880851A (en) * 1971-12-24 1975-04-29 Lilly Co Eli Antibiotic method
CA1109860A (en) 1972-12-08 1981-09-29 Shinji Terao Process for producing lactol-type cephalosporins
JPS49109391A (sl) * 1973-02-28 1974-10-17
JPS5093989A (sl) * 1973-10-25 1975-07-26
JPS5071691A (sl) * 1973-11-02 1975-06-13
JPS5129492A (en) * 1974-09-04 1976-03-12 Sankyo Co Sefuarosuhorinjudotai no seiho
GB1447959A (en) * 1975-02-27 1976-09-02 Shionogi & Co Process for preparing cephem aldehyde derivatives
US4101658A (en) * 1975-06-04 1978-07-18 Shionogi & Co., Ltd. Antibacterial hydrazono cephalosporins
GB8821797D0 (en) * 1988-09-16 1988-10-19 Beecham Group Plc Novel compounds
US5081116A (en) 1989-04-12 1992-01-14 Yamanouchi Pharmaceutical Co., Ltd. Cephalosporin derivatives
JP2895900B2 (ja) * 1990-03-08 1999-05-24 大塚化学株式会社 3―ホルミルセフエム誘導体の製造法
AT400436B (de) * 1992-11-10 1995-12-27 Biochemie Gmbh Neues verfahren zur herstellung von 3-vinylcephalosporinverbindungen
DE69231815T2 (de) * 1991-03-08 2001-09-27 Biochemie Gmbh Verfahren zur Herstellung von Cephalosporinen und Zwischenprodukte in diesem Verfahren
ATE227728T1 (de) 1993-04-16 2002-11-15 Basilea Pharmaceutica Ag Cephalosporin-derivate
US5856474A (en) * 1994-04-25 1999-01-05 Biochemie Gesellschaft, M.B.H. Cephalosporin synthesis

Also Published As

Publication number Publication date
SK285948B6 (sk) 2007-11-02
HU0102726D0 (en) 2001-08-28
CN1326935A (zh) 2001-12-19
AU2407295A (en) 1995-11-16
RU2150471C1 (ru) 2000-06-10
NO964493D0 (no) 1996-10-23
CY2494B1 (en) 2005-09-02
ATE498627T1 (de) 2011-03-15
JPH09512259A (ja) 1997-12-09
CN1344720A (zh) 2002-04-17
DE69536140D1 (de) 2011-03-31
NO318020B1 (no) 2005-01-24
FI963761A0 (fi) 1996-09-20
EP0757691A1 (en) 1997-02-12
SK135796A3 (en) 1997-05-07
BR9507512A (pt) 1997-09-02
CN1092662C (zh) 2002-10-16
TW427992B (en) 2001-04-01
DK0757691T3 (da) 2003-10-27
HU0102725D0 (en) 2001-08-28
EP0757691B1 (en) 2003-07-02
ES2202362T3 (es) 2004-04-01
CZ310696A3 (en) 1997-01-15
FI963761A (fi) 1996-09-20
HU9602940D0 (en) 1996-12-30
CN1145629C (zh) 2004-04-14
NZ329984A (en) 1998-06-26
HUT75229A (en) 1997-04-28
DE69531203T2 (de) 2004-04-22
US5856474A (en) 1999-01-05
KR970702284A (ko) 1997-05-13
JP3302369B2 (ja) 2002-07-15
PT757691E (pt) 2003-11-28
AU686380B2 (en) 1998-02-05
CA2180829C (en) 2008-06-03
RU2225411C2 (ru) 2004-03-10
CA2180829A1 (en) 1995-11-02
CZ297565B6 (cs) 2007-02-07
PL182864B1 (pl) 2002-03-29
NO964493L (no) 1996-10-23
US6063917A (en) 2000-05-16
NZ285084A (en) 1998-05-27
EP1340762A1 (en) 2003-09-03
CN1145628C (zh) 2004-04-14
EP1340762B1 (en) 2011-02-16
PL184773B1 (pl) 2002-12-31
US6034237A (en) 2000-03-07
WO1995029182A1 (en) 1995-11-02
DE69531203D1 (en) 2003-08-07
PL316661A1 (en) 1997-02-03
MX9604353A (es) 1997-06-28
US6093813A (en) 2000-07-25
CN1146770A (zh) 1997-04-02
CA2533837A1 (en) 1995-11-02
ATE244247T1 (de) 2003-07-15
KR100487833B1 (ko) 2005-10-14

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