MX9604353A - Sistensis de cefalosporinas. - Google Patents

Sistensis de cefalosporinas.

Info

Publication number
MX9604353A
MX9604353A MX9604353A MX9604353A MX9604353A MX 9604353 A MX9604353 A MX 9604353A MX 9604353 A MX9604353 A MX 9604353A MX 9604353 A MX9604353 A MX 9604353A MX 9604353 A MX9604353 A MX 9604353A
Authority
MX
Mexico
Prior art keywords
denotes
group
silyl group
hydrogen
denotes hydrogen
Prior art date
Application number
MX9604353A
Other languages
English (en)
Other versions
MXPA96004353A (es
Inventor
Gerd Ascher
Johannes Ludescher
Hubert Sturm
Josef Wieser
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT85794A external-priority patent/AT402927B/de
Priority claimed from AT0085894A external-priority patent/AT402072B/de
Priority claimed from AT0106694A external-priority patent/AT402929B/de
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of MXPA96004353A publication Critical patent/MXPA96004353A/es
Publication of MX9604353A publication Critical patent/MX9604353A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

La presente invencion se relaciona con un compuesto de formula (I), en la cual, alfa) Ra denota hidrogeno o un grupo sililo; Rb denota un grupo de formula -ORc, en la cual Re denota hidrogeno o alquilo; y Rc y Rb juntos denotan un enlace; o beta) Ra y Rd denotan hidrogeno o un grupo sililo; y Rb y Rc juntos denotan un grupo imino de formula = N - Y, en la cual Y denota alquilo, arilo o heterociclilo; y) Rd denota hidrogeno o un grupo sililo; Ra denota hidrogeno, si Rd denota hidrogeno; o, Ra denota hidrogeno o un grupo sililo, se Rd denota un grupo sililo, y Rb y Rc juntos denotan el grupo oxo; en forma libre o en forma de una sal.
MX9604353A 1994-04-25 1995-04-24 Sistensis de cefalosporinas. MX9604353A (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
ATA858/94 1994-04-25
AT85794A AT402927B (de) 1994-04-25 1994-04-25 Neue cefalosporinderivate, verfahren zu ihrer herstellung und ihre verwendung
AT0085894A AT402072B (de) 1994-04-25 1994-04-25 Cephemderivate und verfahren zu ihrer herstellung
ATA857/94 1994-04-25
ATA1066/94 1994-05-25
AT0106694A AT402929B (de) 1994-05-25 1994-05-25 Neue cephalosporinderivate, verfahren zu ihrer herstellung und ihre verwendung
PCT/EP1995/001538 WO1995029182A1 (en) 1994-04-25 1995-04-24 Cephalosporin synthesis

Publications (2)

Publication Number Publication Date
MXPA96004353A MXPA96004353A (es) 1997-06-01
MX9604353A true MX9604353A (es) 1997-06-28

Family

ID=27146806

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9604353A MX9604353A (es) 1994-04-25 1995-04-24 Sistensis de cefalosporinas.

Country Status (26)

Country Link
US (4) US5856474A (es)
EP (2) EP1340762B1 (es)
JP (1) JP3302369B2 (es)
KR (1) KR100487833B1 (es)
CN (3) CN1145628C (es)
AT (2) ATE498627T1 (es)
AU (1) AU686380B2 (es)
BR (1) BR9507512A (es)
CA (2) CA2533837A1 (es)
CY (1) CY2494B1 (es)
CZ (1) CZ297565B6 (es)
DE (2) DE69536140D1 (es)
DK (1) DK0757691T3 (es)
ES (1) ES2202362T3 (es)
FI (1) FI963761A (es)
HU (3) HU0102725D0 (es)
MX (1) MX9604353A (es)
NO (1) NO318020B1 (es)
NZ (2) NZ285084A (es)
PL (2) PL184773B1 (es)
PT (1) PT757691E (es)
RU (2) RU2150471C1 (es)
SI (1) SI0757691T1 (es)
SK (1) SK285948B6 (es)
TW (1) TW427992B (es)
WO (1) WO1995029182A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248881B1 (en) * 1991-03-08 2001-06-19 Biochemie Gmbh Intermediates and process for the production of 3-vinyl cephalosporins
US5856474A (en) * 1994-04-25 1999-01-05 Biochemie Gesellschaft, M.B.H. Cephalosporin synthesis
DE60035925T2 (de) * 1999-07-05 2008-05-15 Basilea Pharmaceutica Ag Verfahren zur Herstellung von Cephalosporin-Derivaten
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
AU6701101A (en) 2000-06-21 2002-01-02 Cubist Pharm Inc Compositions and methods to improve the oral absorption of antimicrobial agents
US7527807B2 (en) * 2000-06-21 2009-05-05 Cubist Pharmaceuticals, Inc. Compositions and methods for increasing the oral absorption of antimicrobials
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
AU2004258944B2 (en) 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
CA2533292C (en) 2003-07-21 2013-12-31 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
CA2533178C (en) 2003-07-21 2014-03-11 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
EP1653925A1 (en) 2003-08-11 2006-05-10 Advancis Pharmaceutical Corporation Robust pellet
JP2007502294A (ja) 2003-08-12 2007-02-08 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
WO2005023184A2 (en) 2003-08-29 2005-03-17 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
CA2538064C (en) 2003-09-15 2013-12-17 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
EP1771158A4 (en) 2004-07-02 2008-03-12 Advancis Pharmaceutical Corp TABLET FOR PULSED DELIVERY
US8968781B2 (en) * 2005-04-29 2015-03-03 Cubist Pharmaceuticals, Inc. Therapeutic compositions
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
WO2010136422A1 (de) * 2009-05-25 2010-12-02 Sandoz Ag Verfahren zur herstellung von ceftobiprol medocaril
ITMI20131820A1 (it) * 2013-11-04 2015-05-05 Laboratorio Chimico Int Spa Procedimento per la preparazione di olopatadina
CN109180704B (zh) * 2018-11-19 2020-06-05 齐鲁安替制药有限公司 一种头孢妥仑匹酯的合成方法
WO2021043973A1 (en) 2019-09-06 2021-03-11 Nabriva Therapeutics GmbH Siderophore cephalosporin conjugates and uses thereof

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3351596A (en) * 1966-09-21 1967-11-07 Lilly Co Eli 3-formyl cephalosporins
CH556876A (de) * 1971-05-19 1974-12-13 Ciba Geigy Ag Verfahren zur herstellung von cephalosporansaeurederivaten.
CH546794A (de) * 1970-06-18 1974-03-15 Ciba Geigy Ag Verfahren zur herstellung von cephalosporansaeurederivaten.
US3674784A (en) * 1970-07-27 1972-07-04 Lilly Co Eli 3-formyl cephalosporin sulfoxides
GB1368231A (en) * 1970-07-31 1974-09-25 Glaxo Lab Ltd Thio-substituted azetidinones and thiazolino azetidinones
US3880851A (en) * 1971-12-24 1975-04-29 Lilly Co Eli Antibiotic method
CA1109860A (en) * 1972-12-08 1981-09-29 Shinji Terao Process for producing lactol-type cephalosporins
JPS49109391A (es) * 1973-02-28 1974-10-17
JPS5093989A (es) * 1973-10-25 1975-07-26
JPS5071691A (es) * 1973-11-02 1975-06-13
JPS5129492A (en) * 1974-09-04 1976-03-12 Sankyo Co Sefuarosuhorinjudotai no seiho
GB1447959A (en) * 1975-02-27 1976-09-02 Shionogi & Co Process for preparing cephem aldehyde derivatives
US4101658A (en) * 1975-06-04 1978-07-18 Shionogi & Co., Ltd. Antibacterial hydrazono cephalosporins
GB8821797D0 (en) * 1988-09-16 1988-10-19 Beecham Group Plc Novel compounds
US5081116A (en) 1989-04-12 1992-01-14 Yamanouchi Pharmaceutical Co., Ltd. Cephalosporin derivatives
JP2895900B2 (ja) * 1990-03-08 1999-05-24 大塚化学株式会社 ３―ホルミルセフエム誘導体の製造法
AT400436B (de) * 1992-11-10 1995-12-27 Biochemie Gmbh Neues verfahren zur herstellung von 3-vinylcephalosporinverbindungen
DE69231815T2 (de) * 1991-03-08 2001-09-27 Biochemie Gmbh Verfahren zur Herstellung von Cephalosporinen und Zwischenprodukte in diesem Verfahren
ES2185634T3 (es) 1993-04-16 2003-05-01 Basilea Pharmaceutica Ag Derivados de cefalosporina.
US5856474A (en) * 1994-04-25 1999-01-05 Biochemie Gesellschaft, M.B.H. Cephalosporin synthesis

Also Published As

Publication number Publication date
CN1145628C (zh) 2004-04-14
EP0757691A1 (en) 1997-02-12
CN1344720A (zh) 2002-04-17
CN1092662C (zh) 2002-10-16
RU2225411C2 (ru) 2004-03-10
DE69536140D1 (de) 2011-03-31
ES2202362T3 (es) 2004-04-01
NO964493L (no) 1996-10-23
HU0102725D0 (en) 2001-08-28
ATE244247T1 (de) 2003-07-15
KR100487833B1 (ko) 2005-10-14
AU2407295A (en) 1995-11-16
EP1340762A1 (en) 2003-09-03
CZ297565B6 (cs) 2007-02-07
US6093813A (en) 2000-07-25
CN1146770A (zh) 1997-04-02
DK0757691T3 (da) 2003-10-27
DE69531203T2 (de) 2004-04-22
CN1326935A (zh) 2001-12-19
WO1995029182A1 (en) 1995-11-02
PL182864B1 (pl) 2002-03-29
BR9507512A (pt) 1997-09-02
ATE498627T1 (de) 2011-03-15
NZ329984A (en) 1998-06-26
JPH09512259A (ja) 1997-12-09
SK285948B6 (sk) 2007-11-02
NZ285084A (en) 1998-05-27
PL184773B1 (pl) 2002-12-31
CA2180829A1 (en) 1995-11-02
CN1145629C (zh) 2004-04-14
KR970702284A (ko) 1997-05-13
FI963761A0 (fi) 1996-09-20
NO964493D0 (no) 1996-10-23
CA2180829C (en) 2008-06-03
SK135796A3 (en) 1997-05-07
SI0757691T1 (en) 2003-12-31
JP3302369B2 (ja) 2002-07-15
DE69531203D1 (en) 2003-08-07
PT757691E (pt) 2003-11-28
CA2533837A1 (en) 1995-11-02
AU686380B2 (en) 1998-02-05
TW427992B (en) 2001-04-01
FI963761A (fi) 1996-09-20
HUT75229A (en) 1997-04-28
US6034237A (en) 2000-03-07
CZ310696A3 (en) 1997-01-15
PL316661A1 (en) 1997-02-03
RU2150471C1 (ru) 2000-06-10
CY2494B1 (en) 2005-09-02
NO318020B1 (no) 2005-01-24
EP0757691B1 (en) 2003-07-02
US5856474A (en) 1999-01-05
HU0102726D0 (en) 2001-08-28
US6063917A (en) 2000-05-16
HU9602940D0 (en) 1996-12-30
EP1340762B1 (en) 2011-02-16

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Legal Events

Date Code Title Description
FG Grant or registration
HC Change of company name or juridical status

Owner name: N.V. ORGANON.*

PD Change of proprietorship

Owner name: NABRIVA THERAPEUTICS FORSCHUNGS GMBH

MM Annulment or lapse due to non-payment of fees