ES8400410A1 - Procedimiento para la preparacion de nuevas sulfiminas. - Google Patents

Procedimiento para la preparacion de nuevas sulfiminas.

Info

Publication number
ES8400410A1
ES8400410A1 ES518826A ES518826A ES8400410A1 ES 8400410 A1 ES8400410 A1 ES 8400410A1 ES 518826 A ES518826 A ES 518826A ES 518826 A ES518826 A ES 518826A ES 8400410 A1 ES8400410 A1 ES 8400410A1
Authority
ES
Spain
Prior art keywords
novel
sulfimine compound
general formula
compounds
sulfimine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518826A
Other languages
English (en)
Other versions
ES518826A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES518826A0 publication Critical patent/ES518826A0/es
Publication of ES8400410A1 publication Critical patent/ES8400410A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE NUEVAS SULFIMINAS.SE HACE REACCIONAR EL COMPUESTO (II) CON H2NO-X-R3 EN EL CUAL X ES UN GRUPO CARBONILO O SULFONILO Y R3 UN GRUPO ARILO DISUSTITUIDO EN POSICION ORTO O UN GRUPO HIDROXILO.LA REACCION TIENE LUGAR EN UN DISOLVENTE Y A TEMPERATURAS COMPRENDIDAS ENTRE 0 Y 50JC. SE OBTIENE EL COMPUESTO (I) EN QUE N VALE 0,01; A ES UN GRUPO METILENO, VINILENO O ETILENO; B ES UN GRUPO ALCOHILENO; R1 UN GRUPO ALCOHILO U OTROS; R2 ES UN ATOMO DE HIDROGENO.ACTIVIDAD ANTITROMBOTICA.
ES518826A 1981-07-25 1983-01-07 Procedimiento para la preparacion de nuevas sulfiminas. Expired ES8400410A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813129444 DE3129444A1 (de) 1981-07-25 1981-07-25 "sulfoximine, deren herstellung und diese verbindungen enthaltende arzneimittel"

Publications (2)

Publication Number Publication Date
ES518826A0 ES518826A0 (es) 1983-10-16
ES8400410A1 true ES8400410A1 (es) 1983-10-16

Family

ID=6137766

Family Applications (4)

Application Number Title Priority Date Filing Date
ES514275A Expired ES8305333A1 (es) 1981-07-25 1982-07-23 "procedimiento para la preparacion de nuevas sulfiminas".
ES518827A Expired ES8400411A1 (es) 1981-07-25 1983-01-07 Procedimiento para la preparacion de nuevas sulfiminas.
ES518826A Expired ES8400410A1 (es) 1981-07-25 1983-01-07 Procedimiento para la preparacion de nuevas sulfiminas.
ES518828A Granted ES518828A0 (es) 1981-07-25 1983-01-07 Procedimiento para la preparacion de nuevas sulfiminas.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES514275A Expired ES8305333A1 (es) 1981-07-25 1982-07-23 "procedimiento para la preparacion de nuevas sulfiminas".
ES518827A Expired ES8400411A1 (es) 1981-07-25 1983-01-07 Procedimiento para la preparacion de nuevas sulfiminas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES518828A Granted ES518828A0 (es) 1981-07-25 1983-01-07 Procedimiento para la preparacion de nuevas sulfiminas.

Country Status (19)

Country Link
JP (1) JPS5824559A (es)
KR (1) KR840000491A (es)
AR (1) AR230745A1 (es)
AU (1) AU556082B2 (es)
CA (1) CA1175430A (es)
CS (1) CS236488B2 (es)
DD (1) DD202871A5 (es)
DE (2) DE3129444A1 (es)
DK (1) DK329582A (es)
ES (4) ES8305333A1 (es)
FI (1) FI822550L (es)
GR (1) GR76181B (es)
HU (1) HU188188B (es)
NO (1) NO822255L (es)
PL (1) PL137725B1 (es)
PT (1) PT75297A (es)
SU (1) SU1158041A3 (es)
YU (1) YU158182A (es)
ZA (1) ZA825273B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2247579B1 (en) * 2008-01-17 2012-04-18 Bayer Pharma Aktiengesellschaft Sulphoximine-substituted quinazoline derivatives as immunomodulators, their preparation and use as medicaments

Also Published As

Publication number Publication date
PL137725B1 (en) 1986-07-31
DK329582A (da) 1983-01-26
ES518826A0 (es) 1983-10-16
PT75297A (fr) 1982-08-01
ES514275A0 (es) 1983-04-01
ZA825273B (en) 1984-03-28
GR76181B (es) 1984-08-03
SU1158041A3 (ru) 1985-05-23
YU158182A (en) 1984-08-31
ES518827A0 (es) 1983-10-16
NO822255L (no) 1983-01-26
FI822550A0 (fi) 1982-07-20
AR230745A1 (es) 1984-06-29
KR840000491A (ko) 1984-02-22
ES8400411A1 (es) 1983-10-16
AU556082B2 (en) 1986-10-23
JPS5824559A (ja) 1983-02-14
ES8305333A1 (es) 1983-04-01
PL237600A1 (en) 1983-03-28
FI822550L (fi) 1983-01-26
CA1175430A (en) 1984-10-02
DD202871A5 (de) 1983-10-05
CS236488B2 (en) 1985-05-15
DE3129444A1 (de) 1983-02-10
DE3246980A1 (de) 1984-06-20
HU188188B (en) 1986-03-28
ES8400412A1 (es) 1983-10-16
ES518828A0 (es) 1983-10-16
AU8637882A (en) 1983-04-14

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