ATE227728T1 - Cephalosporin-derivate - Google Patents

Cephalosporin-derivate

Info

Publication number
ATE227728T1
ATE227728T1 AT94104997T AT94104997T ATE227728T1 AT E227728 T1 ATE227728 T1 AT E227728T1 AT 94104997 T AT94104997 T AT 94104997T AT 94104997 T AT94104997 T AT 94104997T AT E227728 T1 ATE227728 T1 AT E227728T1
Authority
AT
Austria
Prior art keywords
lower alkyl
hydrogen
cycloalkyl
alkenyl
aralkoxy
Prior art date
Application number
AT94104997T
Other languages
English (en)
Inventor
Peter Angehrn
Chung-Chen Wei
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/213,562 external-priority patent/US5523400A/en
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Application granted granted Critical
Publication of ATE227728T1 publication Critical patent/ATE227728T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT94104997T 1993-04-16 1994-03-30 Cephalosporin-derivate ATE227728T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4868893A 1993-04-16 1993-04-16
US08/213,562 US5523400A (en) 1993-04-16 1994-03-21 Cephalosporin antibiotics

Publications (1)

Publication Number Publication Date
ATE227728T1 true ATE227728T1 (de) 2002-11-15

Family

ID=26726411

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94104997T ATE227728T1 (de) 1993-04-16 1994-03-30 Cephalosporin-derivate

Country Status (32)

Country Link
EP (1) EP0620225B1 (de)
JP (1) JP2845752B2 (de)
CN (1) CN1046524C (de)
AT (1) ATE227728T1 (de)
AU (1) AU675695B2 (de)
BG (1) BG61450B1 (de)
BR (1) BR9401503A (de)
CA (1) CA2121324C (de)
CY (1) CY2189B1 (de)
CZ (1) CZ91394A3 (de)
DE (1) DE69431691T2 (de)
DK (1) DK0620225T3 (de)
ES (1) ES2185634T3 (de)
FI (1) FI115525B (de)
GB (1) GB2277737B (de)
GE (1) GEP20002332B (de)
HR (1) HRP940252A2 (de)
HU (2) HUT71252A (de)
IL (1) IL109321A (de)
IS (1) IS4151A (de)
LT (1) LT3289B (de)
LV (1) LV10778B (de)
NO (1) NO305601B1 (de)
NZ (1) NZ260308A (de)
OA (1) OA10064A (de)
PT (1) PT620225E (de)
RU (1) RU2130939C1 (de)
SG (1) SG49814A1 (de)
SK (1) SK42694A3 (de)
TW (1) TW412537B (de)
ZA (1) ZA942612B (de)
ZW (1) ZW4794A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
US5856474A (en) 1994-04-25 1999-01-05 Biochemie Gesellschaft, M.B.H. Cephalosporin synthesis
TR199700859T1 (xx) * 1995-02-27 1998-02-21 F. Hoffmann-La Roche Ag 3-Pirolidiliden-2-on-sefalosporin t�revleri.
US5804577A (en) * 1995-09-12 1998-09-08 Hoffmann-La Roche Inc. Cephalosporin derivatives
EP0761673A1 (de) * 1995-09-12 1997-03-12 F. Hoffmann-La Roche Ag Cephalosporin-Derivate
US5811419A (en) * 1996-01-16 1998-09-22 Hoffmann-La Roche Inc. Isooxacephem-derivatives
US5883247A (en) * 1996-06-10 1999-03-16 Hoffmann-La Roche Inc. Preparation of cephem and isooxacephem derivatives
EP0831093A1 (de) * 1996-09-23 1998-03-25 F. Hoffmann-La Roche Ag 1-Carba-(desthia)-cephalosporinderivate
SG53049A1 (en) * 1996-09-23 1998-09-28 Hoffmann La Roche 1-carba-(dethia)-cephalosporin derivatives
EP0838465A1 (de) * 1996-10-22 1998-04-29 F. Hoffmann-La Roche Ag Pyridinium-substituierte (Lactamylvinyl)-Cephalosporin Derivate, deren Herstellung und deren Verwendung als Antibiotika
TW446707B (en) * 1996-10-22 2001-07-21 Hoffmann La Roche Cephalosporin pyridinium derivatives
DE69737382T2 (de) * 1996-11-06 2007-10-31 Basilea Pharmaceutica Ag Vinylpyrrolidinon-Cephalosporin-Derivate
TW415949B (en) * 1996-12-19 2000-12-21 Hoffmann La Roche Vinyl pyrrolidine cephalosporin derivatives with basic substituents
US6114541A (en) * 1997-03-10 2000-09-05 Hoffmann-La Roche Inc. Method for the preparation of α-Bromo-Lactam derivatives
US6150350A (en) * 1997-09-15 2000-11-21 Hoffman-La Roche Inc. Antimicrobial compositions
ATE370146T1 (de) * 1999-07-05 2007-09-15 Basilea Pharmaceutica Ag Verfahren zur herstellung von cephalosporin- derivaten
KR100342944B1 (ko) * 1999-11-08 2002-07-02 민경윤 고순도 세프포독심 프록세틸의 제조방법
ATE341642T1 (de) 2000-04-19 2006-10-15 Basilea Pharmaceutica Ag Verfahren zur herstellung von d- asparaginderivaten
US6504025B2 (en) * 2000-05-24 2003-01-07 Basilea Pharmaceutica Ag Process for the preparation of vinyl-pyrrolidinone cephalosporin derivatives
US20090176206A1 (en) * 2004-03-04 2009-07-09 James Russell Toll-like receptor 2 (tlr-2) haplotypes predict outcome of patients
CN101309916A (zh) * 2005-11-18 2008-11-19 卫材R&D管理有限公司 制备肉桂酰胺衍生物的方法
CN101245077B (zh) * 2007-02-14 2010-06-02 山东轩竹医药科技有限公司 头孢菌素衍生物
JP5403205B2 (ja) * 2007-10-29 2014-01-29 日産化学工業株式会社 ２−アミノ−ｎ−（２，２，２−トリフルオロエチル）アセトアミド化合物又はその塩の製造方法
UY35103A (es) 2012-10-29 2014-05-30 Glaxo Group Ltd Compuestos de cefem 2-sustituidos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3971778A (en) * 1972-05-12 1976-07-27 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position
JPS5854157B2 (ja) 1977-06-10 1983-12-02 山之内製薬株式会社 セフアロスポリン化合物の新規誘導体ならびにその製造方法
US4255423A (en) * 1977-07-27 1981-03-10 Merck & Co., Inc. Cephalosporin compounds
JPH0686463B2 (ja) * 1988-07-01 1994-11-02 明治製菓株式会社 新規セフェム化合物、その製造法及び抗菌剤
GB8821797D0 (en) * 1988-09-16 1988-10-19 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
HU9401080D0 (en) 1994-07-28
FI115525B (fi) 2005-05-31
LV10778A (lv) 1995-08-20
DE69431691T2 (de) 2003-08-21
GB9407400D0 (en) 1994-06-08
LTIP1916A (en) 1994-11-25
LT3289B (en) 1995-06-26
OA10064A (fr) 1996-10-14
AU5949494A (en) 1994-10-20
CA2121324C (en) 2007-07-10
HRP940252A2 (en) 1996-08-31
GEP20002332B (en) 2000-12-25
HK1000423A1 (en) 1998-03-20
AU675695B2 (en) 1997-02-13
EP0620225B1 (de) 2002-11-13
HUT71252A (en) 1995-11-28
FI941775L (fi) 1994-10-17
HU211652A9 (en) 1995-12-28
BR9401503A (pt) 1994-10-25
NZ260308A (en) 1996-05-28
NO941342D0 (no) 1994-04-14
NO941342L (no) 1994-10-17
JP2845752B2 (ja) 1999-01-13
IL109321A (en) 1998-07-15
RU2130939C1 (ru) 1999-05-27
PT620225E (pt) 2003-03-31
CN1105365A (zh) 1995-07-19
FI941775A0 (fi) 1994-04-15
TW412537B (en) 2000-11-21
CA2121324A1 (en) 1994-10-17
ZW4794A1 (en) 1995-01-05
IS4151A (is) 1994-10-17
BG61450B1 (bg) 1997-08-29
CZ91394A3 (en) 1994-11-16
EP0620225A1 (de) 1994-10-19
IL109321A0 (en) 1994-07-31
DE69431691D1 (de) 2002-12-19
JPH06321954A (ja) 1994-11-22
BG98723A (en) 1995-03-31
CN1046524C (zh) 1999-11-17
ZA942612B (en) 1994-10-17
NO305601B1 (no) 1999-06-28
GB2277737A (en) 1994-11-09
CY2189B1 (en) 2002-11-08
SG49814A1 (en) 1998-06-15
ES2185634T3 (es) 2003-05-01
DK0620225T3 (da) 2003-03-17
SK42694A3 (en) 1995-02-08
GB2277737B (en) 1996-09-25
LV10778B (en) 1996-06-20

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