SG49814A1 - Cephalosporin derivatives - Google Patents

Cephalosporin derivatives

Info

Publication number
SG49814A1
SG49814A1 SG1996006705A SG1996006705A SG49814A1 SG 49814 A1 SG49814 A1 SG 49814A1 SG 1996006705 A SG1996006705 A SG 1996006705A SG 1996006705 A SG1996006705 A SG 1996006705A SG 49814 A1 SG49814 A1 SG 49814A1
Authority
SG
Singapore
Prior art keywords
lower alkyl
hydrogen
cycloalkyl
alkenyl
aralkoxy
Prior art date
Application number
SG1996006705A
Other languages
English (en)
Inventor
Chung-Chen Wei
Peter Angehrn
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/213,562 external-priority patent/US5523400A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SG49814A1 publication Critical patent/SG49814A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG1996006705A 1993-04-16 1996-03-28 Cephalosporin derivatives SG49814A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4868893A 1993-04-16 1993-04-16
US08/213,562 US5523400A (en) 1993-04-16 1994-03-21 Cephalosporin antibiotics

Publications (1)

Publication Number Publication Date
SG49814A1 true SG49814A1 (en) 1998-06-15

Family

ID=26726411

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996006705A SG49814A1 (en) 1993-04-16 1996-03-28 Cephalosporin derivatives

Country Status (33)

Country Link
EP (1) EP0620225B1 (de)
JP (1) JP2845752B2 (de)
CN (1) CN1046524C (de)
AT (1) ATE227728T1 (de)
AU (1) AU675695B2 (de)
BG (1) BG61450B1 (de)
BR (1) BR9401503A (de)
CA (1) CA2121324C (de)
CY (1) CY2189B1 (de)
CZ (1) CZ91394A3 (de)
DE (1) DE69431691T2 (de)
DK (1) DK0620225T3 (de)
ES (1) ES2185634T3 (de)
FI (1) FI115525B (de)
GB (1) GB2277737B (de)
GE (1) GEP20002332B (de)
HK (1) HK1000423A1 (de)
HR (1) HRP940252A2 (de)
HU (2) HUT71252A (de)
IL (1) IL109321A (de)
IS (1) IS4151A (de)
LT (1) LT3289B (de)
LV (1) LV10778B (de)
NO (1) NO305601B1 (de)
NZ (1) NZ260308A (de)
OA (1) OA10064A (de)
PT (1) PT620225E (de)
RU (1) RU2130939C1 (de)
SG (1) SG49814A1 (de)
SK (1) SK42694A3 (de)
TW (1) TW412537B (de)
ZA (1) ZA942612B (de)
ZW (1) ZW4794A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
US5856474A (en) 1994-04-25 1999-01-05 Biochemie Gesellschaft, M.B.H. Cephalosporin synthesis
CN1176641A (zh) * 1995-02-27 1998-03-18 弗·哈夫曼-拉罗切有限公司 3-吡咯烷亚基-2-酮-头孢菌素衍生物
EP0761673A1 (de) * 1995-09-12 1997-03-12 F. Hoffmann-La Roche Ag Cephalosporin-Derivate
CZ251896A3 (en) * 1995-09-12 1997-04-16 Hoffmann Ka Roche Ag F Cephalosporin derivatives
US5811419A (en) * 1996-01-16 1998-09-22 Hoffmann-La Roche Inc. Isooxacephem-derivatives
US5883247A (en) * 1996-06-10 1999-03-16 Hoffmann-La Roche Inc. Preparation of cephem and isooxacephem derivatives
SG53049A1 (en) * 1996-09-23 1998-09-28 Hoffmann La Roche 1-carba-(dethia)-cephalosporin derivatives
EP0831093A1 (de) * 1996-09-23 1998-03-25 F. Hoffmann-La Roche Ag 1-Carba-(desthia)-cephalosporinderivate
EP0838465A1 (de) * 1996-10-22 1998-04-29 F. Hoffmann-La Roche Ag Pyridinium-substituierte (Lactamylvinyl)-Cephalosporin Derivate, deren Herstellung und deren Verwendung als Antibiotika
TW446707B (en) * 1996-10-22 2001-07-21 Hoffmann La Roche Cephalosporin pyridinium derivatives
DK0841339T3 (da) * 1996-11-06 2007-07-02 Basilea Pharmaceutica Ag Vinylpyrrolidinon-cephalosporinderivater
TW415949B (en) * 1996-12-19 2000-12-21 Hoffmann La Roche Vinyl pyrrolidine cephalosporin derivatives with basic substituents
US6114541A (en) * 1997-03-10 2000-09-05 Hoffmann-La Roche Inc. Method for the preparation of α-Bromo-Lactam derivatives
US6150350A (en) * 1997-09-15 2000-11-21 Hoffman-La Roche Inc. Antimicrobial compositions
EP1067131B1 (de) * 1999-07-05 2007-08-15 Basilea Pharmaceutica AG Verfahren zur Herstellung von Cephalosporin-Derivaten
KR100342944B1 (ko) * 1999-11-08 2002-07-02 민경윤 고순도 세프포독심 프록세틸의 제조방법
DK1148140T3 (da) 2000-04-19 2007-01-08 Basilea Pharmaceutica Ag Fremgangsmåde til fremstilling af D-asparaginderivater
US6504025B2 (en) * 2000-05-24 2003-01-07 Basilea Pharmaceutica Ag Process for the preparation of vinyl-pyrrolidinone cephalosporin derivatives
WO2005085274A1 (en) * 2004-03-04 2005-09-15 The University Of British Columbia Toll-like receptor 2 (tlr-2) haplotypes predict outcome of patients
AU2006316005A1 (en) * 2005-11-18 2007-05-24 Eisai R & D Management Co., Ltd. Process for production of cinnamamide derivative
CN101245081B (zh) * 2007-02-14 2010-10-13 山东轩竹医药科技有限公司 头孢菌素衍生物
JP5403205B2 (ja) * 2007-10-29 2014-01-29 日産化学工業株式会社 2−アミノ−n−(2,2,2−トリフルオロエチル)アセトアミド化合物又はその塩の製造方法
UY35103A (es) 2012-10-29 2014-05-30 Glaxo Group Ltd Compuestos de cefem 2-sustituidos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3971778A (en) * 1972-05-12 1976-07-27 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position
JPS5854157B2 (ja) 1977-06-10 1983-12-02 山之内製薬株式会社 セフアロスポリン化合物の新規誘導体ならびにその製造方法
US4255423A (en) * 1977-07-27 1981-03-10 Merck & Co., Inc. Cephalosporin compounds
JPH0686463B2 (ja) * 1988-07-01 1994-11-02 明治製菓株式会社 新規セフェム化合物、その製造法及び抗菌剤
GB8821797D0 (en) * 1988-09-16 1988-10-19 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
CN1105365A (zh) 1995-07-19
GB2277737A (en) 1994-11-09
LV10778B (en) 1996-06-20
ZA942612B (en) 1994-10-17
FI941775A (fi) 1994-10-17
IL109321A0 (en) 1994-07-31
GB9407400D0 (en) 1994-06-08
OA10064A (fr) 1996-10-14
HUT71252A (en) 1995-11-28
NO941342L (no) 1994-10-17
CZ91394A3 (en) 1994-11-16
JP2845752B2 (ja) 1999-01-13
CA2121324C (en) 2007-07-10
NO941342D0 (no) 1994-04-14
ATE227728T1 (de) 2002-11-15
CN1046524C (zh) 1999-11-17
ZW4794A1 (en) 1995-01-05
IS4151A (is) 1994-10-17
CA2121324A1 (en) 1994-10-17
EP0620225A1 (de) 1994-10-19
ES2185634T3 (es) 2003-05-01
BG61450B1 (bg) 1997-08-29
HU211652A9 (en) 1995-12-28
LTIP1916A (en) 1994-11-25
TW412537B (en) 2000-11-21
AU675695B2 (en) 1997-02-13
BG98723A (en) 1995-03-31
HRP940252A2 (en) 1996-08-31
PT620225E (pt) 2003-03-31
RU2130939C1 (ru) 1999-05-27
GB2277737B (en) 1996-09-25
IL109321A (en) 1998-07-15
NZ260308A (en) 1996-05-28
BR9401503A (pt) 1994-10-25
DK0620225T3 (da) 2003-03-17
EP0620225B1 (de) 2002-11-13
SK42694A3 (en) 1995-02-08
HK1000423A1 (en) 1998-03-20
DE69431691T2 (de) 2003-08-21
NO305601B1 (no) 1999-06-28
FI941775A0 (fi) 1994-04-15
AU5949494A (en) 1994-10-20
LT3289B (en) 1995-06-26
CY2189B1 (en) 2002-11-08
FI115525B (fi) 2005-05-31
DE69431691D1 (de) 2002-12-19
HU9401080D0 (en) 1994-07-28
GEP20002332B (en) 2000-12-25
JPH06321954A (ja) 1994-11-22
LV10778A (lv) 1995-08-20

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