DK1148140T3 - Fremgangsmåde til fremstilling af D-asparaginderivater - Google Patents

Fremgangsmåde til fremstilling af D-asparaginderivater

Info

Publication number
DK1148140T3
DK1148140T3 DK01108896T DK01108896T DK1148140T3 DK 1148140 T3 DK1148140 T3 DK 1148140T3 DK 01108896 T DK01108896 T DK 01108896T DK 01108896 T DK01108896 T DK 01108896T DK 1148140 T3 DK1148140 T3 DK 1148140T3
Authority
DK
Denmark
Prior art keywords
formula
preparation
derivatives
useful
asparagine
Prior art date
Application number
DK01108896T
Other languages
English (en)
Inventor
Beat Wirz
Hans Iding
Mark Rogers-Evana
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Application granted granted Critical
Publication of DK1148140T3 publication Critical patent/DK1148140T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/20Aspartic acid; Asparagine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pyrrole Compounds (AREA)
DK01108896T 2000-04-19 2001-04-10 Fremgangsmåde til fremstilling af D-asparaginderivater DK1148140T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00108542 2000-04-19

Publications (1)

Publication Number Publication Date
DK1148140T3 true DK1148140T3 (da) 2007-01-08

Family

ID=8168510

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01108896T DK1148140T3 (da) 2000-04-19 2001-04-10 Fremgangsmåde til fremstilling af D-asparaginderivater

Country Status (7)

Country Link
US (1) US6420166B2 (da)
EP (1) EP1148140B1 (da)
JP (1) JP3568914B2 (da)
AT (1) ATE341642T1 (da)
DE (1) DE60123513T2 (da)
DK (1) DK1148140T3 (da)
ES (1) ES2272372T3 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100413972C (zh) * 2001-09-25 2008-08-27 弗·哈夫曼-拉罗切有限公司 制备取代的2-氨基-3-(2-氨基-苯硫基)-丙酸的酶催化方法
CN108531525A (zh) * 2018-05-09 2018-09-14 宿州学院 一种l-天冬氨酸的酶法转化制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2511867A (en) * 1949-12-19 1950-06-20 Method fob separating enantiomers
US4211840A (en) 1977-06-08 1980-07-08 Ajinomoto Company, Incorporated Method for producing D-α-amino acid
US4670395A (en) * 1984-11-13 1987-06-02 The Standard Oil Company Enantioselective hydrolysis of N-acylamino acid esters using a combined enzyme system
US5081024A (en) * 1988-09-05 1992-01-14 Nissan Chemical Industries, Ltd. Process for producing optically active amino acids
ATE227728T1 (de) 1993-04-16 2002-11-15 Basilea Pharmaceutica Ag Cephalosporin-derivate
IT237452Y1 (it) 1996-06-19 2000-09-13 Rothenberger Werkzeuge Ag Dispositivo di congelamento per tubazioni piene di liquido
TW415949B (en) 1996-12-19 2000-12-21 Hoffmann La Roche Vinyl pyrrolidine cephalosporin derivatives with basic substituents
JP4063400B2 (ja) * 1997-07-31 2008-03-19 ダイセル化学工業株式会社 D−アミノアシラーゼ
US5977381A (en) * 1998-01-12 1999-11-02 Hoffmann-La Roche Inc. Process for making 3-amino-pyrolidine derivatives
JPH11318442A (ja) * 1998-03-17 1999-11-24 Daicel Chem Ind Ltd D―アミノアシラ―ゼ
HUP0105426A3 (en) 1998-06-15 2002-12-28 Hoffmann La Roche Derivatives of 3-(2-oxo-[1,3']bipyrrolidinyl-3-ylidenemethyl)-cephems and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
JP2001309798A (ja) 2001-11-06
EP1148140A1 (en) 2001-10-24
JP3568914B2 (ja) 2004-09-22
ES2272372T3 (es) 2007-05-01
ATE341642T1 (de) 2006-10-15
DE60123513T2 (de) 2007-05-10
EP1148140B1 (en) 2006-10-04
US20010049127A1 (en) 2001-12-06
DE60123513D1 (de) 2006-11-16
US6420166B2 (en) 2002-07-16

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