DE60123513D1 - Verfahren zur Herstellung von D-Asparaginderivaten - Google Patents

Verfahren zur Herstellung von D-Asparaginderivaten

Info

Publication number
DE60123513D1
DE60123513D1 DE60123513T DE60123513T DE60123513D1 DE 60123513 D1 DE60123513 D1 DE 60123513D1 DE 60123513 T DE60123513 T DE 60123513T DE 60123513 T DE60123513 T DE 60123513T DE 60123513 D1 DE60123513 D1 DE 60123513D1
Authority
DE
Germany
Prior art keywords
formula
preparation
derivatives
useful
asparagine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60123513T
Other languages
English (en)
Other versions
DE60123513T2 (de
Inventor
Hans Iding
Mark Rogers-Evana
Beat Wirz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Basilea Pharmaceutica AG
Original Assignee
Basilea Pharmaceutica AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica AG filed Critical Basilea Pharmaceutica AG
Application granted granted Critical
Publication of DE60123513D1 publication Critical patent/DE60123513D1/de
Publication of DE60123513T2 publication Critical patent/DE60123513T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/20—Aspartic acid; Asparagine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pyrrole Compounds (AREA)
DE60123513T 2000-04-19 2001-04-10 Verfahren zur Herstellung von D-Asparaginderivaten Expired - Lifetime DE60123513T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00108542 2000-04-19
EP00108542 2000-04-19

Publications (2)

Publication Number Publication Date
DE60123513D1 true DE60123513D1 (de) 2006-11-16
DE60123513T2 DE60123513T2 (de) 2007-05-10

Family

ID=8168510

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60123513T Expired - Lifetime DE60123513T2 (de) 2000-04-19 2001-04-10 Verfahren zur Herstellung von D-Asparaginderivaten

Country Status (7)

Country Link
US (1) US6420166B2 (de)
EP (1) EP1148140B1 (de)
JP (1) JP3568914B2 (de)
AT (1) ATE341642T1 (de)
DE (1) DE60123513T2 (de)
DK (1) DK1148140T3 (de)
ES (1) ES2272372T3 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2278061T3 (es) * 2001-09-25 2007-08-01 F. Hoffmann-La Roche Ag Proceso enzimatico para preparacion del acido 2-amino-3-(2-amino-fenilsulfanil)-propionico sustituido.
CN108531525A (zh) * 2018-05-09 2018-09-14 宿州学院 一种l-天冬氨酸的酶法转化制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2511867A (en) 1949-12-19 1950-06-20 Method fob separating enantiomers
US4211840A (en) 1977-06-08 1980-07-08 Ajinomoto Company, Incorporated Method for producing D-α-amino acid
US4670395A (en) * 1984-11-13 1987-06-02 The Standard Oil Company Enantioselective hydrolysis of N-acylamino acid esters using a combined enzyme system
US5081024A (en) * 1988-09-05 1992-01-14 Nissan Chemical Industries, Ltd. Process for producing optically active amino acids
PT620225E (pt) 1993-04-16 2003-03-31 Basilea Pharmaceutica Ag Derivados de cefalosporina
IT237452Y1 (it) 1996-06-19 2000-09-13 Rothenberger Werkzeuge Ag Dispositivo di congelamento per tubazioni piene di liquido
TW415949B (en) 1996-12-19 2000-12-21 Hoffmann La Roche Vinyl pyrrolidine cephalosporin derivatives with basic substituents
JP4063400B2 (ja) * 1997-07-31 2008-03-19 ダイセル化学工業株式会社 Ｄ−アミノアシラーゼ
US5977381A (en) * 1998-01-12 1999-11-02 Hoffmann-La Roche Inc. Process for making 3-amino-pyrolidine derivatives
JPH11318442A (ja) * 1998-03-17 1999-11-24 Daicel Chem Ind Ltd Ｄ―アミノアシラ―ゼ
IL139872A0 (en) 1998-06-15 2002-02-10 Hoffmann La Roche Derivatives of 3-(2-oxo-[1,3'] bipyrrolidinyl-3-ylidenemethyl) cephems

Also Published As

Publication number Publication date
US20010049127A1 (en) 2001-12-06
US6420166B2 (en) 2002-07-16
ES2272372T3 (es) 2007-05-01
JP3568914B2 (ja) 2004-09-22
JP2001309798A (ja) 2001-11-06
EP1148140A1 (de) 2001-10-24
EP1148140B1 (de) 2006-10-04
DE60123513T2 (de) 2007-05-10
ATE341642T1 (de) 2006-10-15
DK1148140T3 (da) 2007-01-08

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