SI0667353T1 - Glycopeptide antibiotic derivatives - Google Patents

Glycopeptide antibiotic derivatives

Info

Publication number
SI0667353T1
SI0667353T1 SI9530697T SI9530697T SI0667353T1 SI 0667353 T1 SI0667353 T1 SI 0667353T1 SI 9530697 T SI9530697 T SI 9530697T SI 9530697 T SI9530697 T SI 9530697T SI 0667353 T1 SI0667353 T1 SI 0667353T1
Authority
SI
Slovenia
Prior art keywords
glycopeptide antibiotic
antibiotic derivatives
derivatives
glycopeptide
mixed
Prior art date
Application number
SI9530697T
Other languages
English (en)
Slovenian (sl)
Inventor
Robin David Grey Cooper
Bret Eugene Huff
Thalia Ioanna Nicas
John Thomas Quatroche
Michael John Rodriguez
Nancy June Snyder
Michael Alexander Staszak
Richard Craig Thompson
Stephen Charles Wilkie
Mark James Zweifel
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of SI0667353T1 publication Critical patent/SI0667353T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
SI9530697T 1994-01-28 1995-01-25 Glycopeptide antibiotic derivatives SI0667353T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18939394A 1994-01-28 1994-01-28
US35641394A 1994-12-15 1994-12-15
EP00200988A EP1016670B1 (en) 1994-01-28 1995-01-25 Glycopeptide antibiotic derivatives
EP95300429A EP0667353B1 (en) 1994-01-28 1995-01-25 Glycopeptide antibiotic derivatives

Publications (1)

Publication Number Publication Date
SI0667353T1 true SI0667353T1 (en) 2004-04-30

Family

ID=26885101

Family Applications (2)

Application Number Title Priority Date Filing Date
SI9530697T SI0667353T1 (en) 1994-01-28 1995-01-25 Glycopeptide antibiotic derivatives
SI9530681T SI1016670T1 (en) 1994-01-28 1995-01-25 Glycopeptide antibiotic derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI9530681T SI1016670T1 (en) 1994-01-28 1995-01-25 Glycopeptide antibiotic derivatives

Country Status (30)

Country Link
US (1) US5843889A (pt)
EP (3) EP0667353B1 (pt)
JP (1) JP3756539B2 (pt)
KR (1) KR100388867B1 (pt)
CN (1) CN1071334C (pt)
AT (3) ATE266042T1 (pt)
AU (1) AU703106B2 (pt)
BR (1) BR9500365A (pt)
CA (3) CA2546910C (pt)
CO (1) CO4600679A1 (pt)
CZ (2) CZ292895B6 (pt)
DE (3) DE69533004T2 (pt)
DK (3) DK1031576T3 (pt)
EG (1) EG25884A (pt)
ES (3) ES2204444T3 (pt)
FI (3) FI117095B (pt)
HU (1) HU225164B1 (pt)
IL (1) IL112457A (pt)
MY (1) MY128335A (pt)
NO (1) NO323103B1 (pt)
NZ (1) NZ270387A (pt)
PE (1) PE40996A1 (pt)
PL (1) PL180961B1 (pt)
PT (3) PT667353E (pt)
RU (1) RU2145609C1 (pt)
SG (1) SG52719A1 (pt)
SI (2) SI0667353T1 (pt)
TW (1) TW457248B (pt)
UA (1) UA43323C2 (pt)
YU (1) YU4995A (pt)

Families Citing this family (52)

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US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
US5919756A (en) * 1996-06-28 1999-07-06 Eli Lilly And Company Amides
US5939382A (en) * 1996-11-21 1999-08-17 Eli Lilly And Company Reducing agent for reductive alkylation of glycopeptide antibiotics
US5952466A (en) * 1997-11-12 1999-09-14 Eli Lilly And Company Reductive alkylation of glycopeptide antibiotics
ID18900A (id) * 1996-11-21 1998-05-20 Lilly Co Eli Alkilasi menurun dari gliko peptida anti biotik
US5919771A (en) * 1997-05-20 1999-07-06 Eli Lilly And Company Urea and thiourea derivatives of glycopeptides
US5952310A (en) * 1997-05-20 1999-09-14 Eli Lilly And Company Glycopeptide hexapeptides
US5977063A (en) * 1997-05-20 1999-11-02 Eli Lilly And Company Alkylated hexapeptides
US5994297A (en) * 1997-08-22 1999-11-30 Eli Lilly And Company Therapy for Staphylococcus aureus
US6518242B1 (en) 1998-02-20 2003-02-11 Theravance, Inc. Derivatives of glycopeptide antibacterial agents
EP1073447B1 (en) 1998-05-01 2007-05-09 Eli Lilly And Company N1-modified glycopeptides
US6710168B1 (en) * 1999-05-19 2004-03-23 The Trustees Of The University Of Princeton Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
CA2337103A1 (en) * 1998-07-14 2000-01-27 Robert Kerns Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
DE69908819T2 (de) 1998-12-23 2004-05-06 Theravance, Inc., South San Francisco Glycopeptid-derivate und pharmazeutische zusammensetzungen, die sie enthalten
CA2726789A1 (en) 2000-02-05 2001-11-08 Theravance, Inc. Cyclodextrin containing glycopeptide antibiotic compositions
WO2001081373A2 (en) * 2000-04-25 2001-11-01 Merck & Co., Inc. Glycopeptide antibacterial compounds and methods of using same
WO2001083520A2 (en) 2000-05-02 2001-11-08 Theravance,Inc Polyacid glycopeptide derivatives
JP4713810B2 (ja) * 2000-05-02 2011-06-29 セラヴァンス， インコーポレーテッド グリコペプチドに対する還元的アルキル化プロセス
UA75083C2 (uk) 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
EP1292611B1 (en) 2000-06-22 2008-03-12 Theravance, Inc. Glycopeptide carboxy-saccharide derivatives
US6872804B2 (en) 2000-06-22 2005-03-29 Theravance, Inc. Glycopeptide disulfide and thioester derivatives
WO2001098329A1 (en) 2000-06-22 2001-12-27 Theravance, Inc. Polyhydroxy glycopeptide derivatives
TWI312785B (en) 2001-08-24 2009-08-01 Theravance Inc Process for preparing vancomycin derivatives
TWI275594B (en) 2001-08-24 2007-03-11 Theravance Inc Process for preparing vancomycin phosphonate derivatives
TWI233932B (en) * 2001-08-24 2005-06-11 Theravance Inc Process for purifying glycopeptide phosphonate derivatives
CA2497159A1 (en) * 2002-08-30 2004-03-11 K.U. Leuven Research And Development Glycopeptide antibiotic and semisynthetic derivatives thereof and their use as antiviral agents
EP1624858B1 (en) 2003-04-09 2018-06-06 Rutgers, the State University of New Jersey Novel encochleation methods
US7521418B2 (en) 2003-05-27 2009-04-21 Theravance, Inc. Use of a polyene macrolide antifungal agent in combination with a glycopeptide antibacterial agent
WO2005018743A1 (en) * 2003-07-22 2005-03-03 Theravance, Inc. Use of an echinocandin antifungal agent in combination with a glycopeptide antibacterial agent
BRPI0516657A (pt) * 2004-11-29 2008-09-16 Univ Nagoya Nat Univ Corp derivados de monÈmero antibiótico de glicopeptìdeo
US7632918B2 (en) 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
EP2628837B1 (en) 2005-04-01 2017-01-04 Buckeye Technologies Inc. Nonwoven material for acoustic insulation, and process for manufacture
CA2623198C (en) 2005-09-22 2014-08-05 Medivas, Llc Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
EP1933881B1 (en) 2005-09-22 2019-03-13 Medivas, LLC Solid polymer delivery compositions and methods for use thereof
TW200808818A (en) * 2006-05-26 2008-02-16 Shionogi & Co Glycopeptide antibiotic derivatives
WO2009081958A1 (ja) 2007-12-26 2009-07-02 Shionogi & Co., Ltd. グリコペプチド抗生物質配糖化誘導体
US8841440B2 (en) 2008-04-01 2014-09-23 Cornell University Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof
CN101343313B (zh) * 2008-09-03 2011-11-16 南京农业大学 一种葡萄糖二肽类化合物及其制备方法和用途
WO2012151517A1 (en) 2011-05-05 2012-11-08 Coordinated Program Development, Llc Cochleate compositions and methods of making and using same
BR112015023044A8 (pt) 2013-03-15 2021-09-28 Melinta Subsidiary Corp Métodos para tratar infecções em pacientes acima do peso e obesos com o uso de antibióticos
CN104418941B (zh) * 2013-08-19 2017-11-07 爱斯医药科技(南京)有限公司 万古霉素衍生物、制备方法及其应用
WO2015040467A1 (en) 2013-09-23 2015-03-26 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Vancomycin-sugar conjugates and uses thereof
AU2015289602B2 (en) * 2014-07-17 2020-06-25 Abbvie Inc. High purity oritavancin and method of producing same
EA035368B1 (ru) 2014-11-06 2020-06-03 Кселлия Фармасьютикалз Апс Композиции гликопептидов
US20170342110A1 (en) * 2014-12-25 2017-11-30 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Glycopeptides and uses thereof
CN106188243B (zh) * 2015-05-05 2020-06-26 博瑞生物医药（苏州）股份有限公司 一种奥利万星的制备方法
CN106467570B (zh) * 2015-08-14 2020-04-07 正大天晴药业集团股份有限公司 糖肽类抗生素的还原烷基化方法
CN107434823B (zh) * 2016-05-26 2021-11-16 江苏恒瑞医药股份有限公司 一种奥利万星中间体a82846b的纯化方法
CN108409837B (zh) * 2018-03-06 2021-09-24 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用
CN109053864B (zh) * 2018-07-10 2021-08-24 丽珠集团新北江制药股份有限公司 一种制备奥利万星的方法
CN109053865B (zh) * 2018-07-20 2021-04-13 丽珠集团新北江制药股份有限公司 一种羧基保护制备奥利万星的方法
US20230218644A1 (en) 2020-04-16 2023-07-13 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

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US3067099A (en) * 1955-09-16 1962-12-04 Lilly Co Eli Vancomycin and method for its preparation
US3338786A (en) * 1966-07-29 1967-08-29 American Cyanamid Co Antibiotic av290 and production thereof
US4552886A (en) * 1982-06-07 1985-11-12 Eli Lilly And Company Fungicidal pyridylmethyl-amines
IT1173329B (it) * 1984-02-21 1987-06-24 Lepetit Spa Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3
GB8415093D0 (en) * 1984-06-13 1984-07-18 Lepetit Spa Antibiotic l 17392
IL78597A0 (en) * 1985-04-25 1986-08-31 Lilly Co Eli Novel glycopeptide derivatives
US4698327A (en) * 1985-04-25 1987-10-06 Eli Lilly And Company Novel glycopeptide derivatives
US4643987A (en) * 1985-08-14 1987-02-17 Eli Lilly And Company Modified glycopeptides
US4639433A (en) * 1985-08-14 1987-01-27 Eli Lilly And Company Glycopeptide derivatives
US4946941A (en) * 1986-01-24 1990-08-07 Shionogi & Co., Ltd. Novel glycopeptide antibiotics
EG18377A (en) * 1986-09-19 1993-04-30 Lilly Co Eli Process for preparing glycopeptide antibiotics
GB8701872D0 (en) * 1987-01-28 1987-03-04 Lepetit Spa N15-alkyl & n15,n15-dialkyl derivatives
US5071749A (en) * 1987-04-16 1991-12-10 Shionogi & Co., Ltd. Glycopetide antibiotic pa-45052-b
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CA1339808C (en) * 1988-10-19 1998-04-07 Manuel Debono Glycopeptide antibiotics
US5194424A (en) * 1988-12-27 1993-03-16 Gruppo Lepetit Spa C63 -amide derivatives of 34-de(acetylglucosaminyl)-34-deoxy-teicoplanin and their use as medicaments against bacteria resistant to glycopeptide antibiotics
US5185320A (en) * 1989-04-03 1993-02-09 Gruppo Lepetit S.P.A. O56 -alkyl derivatives of aglycone and pseudo aglycones of teicoplanin
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Also Published As

Publication number Publication date
CA2546910A1 (en) 1995-07-29
CA2546625C (en) 2008-09-09
EP1031576A3 (en) 2000-12-27
EP1016670B1 (en) 2003-09-03
EP1031576A2 (en) 2000-08-30
CN1119649A (zh) 1996-04-03
FI117095B (fi) 2006-06-15
CA2141106A1 (en) 1995-07-29
UA43323C2 (uk) 2001-12-17
KR950032274A (ko) 1995-12-20
IL112457A (en) 2004-06-20
DK1016670T3 (da) 2004-01-05
DK0667353T3 (da) 2004-03-22
SI1016670T1 (en) 2004-02-29
ATE253077T1 (de) 2003-11-15
YU4995A (sh) 1998-07-10
DE69532013D1 (de) 2003-12-04
EP1031576B1 (en) 2004-05-06
FI20050513A (fi) 2005-05-13
CA2546625A1 (en) 1995-07-29
NO323103B1 (no) 2007-01-02
PE40996A1 (es) 1996-10-14
ES2220335T3 (es) 2004-12-16
CN1071334C (zh) 2001-09-19
AU703106B2 (en) 1999-03-18
CA2546910C (en) 2010-09-14
DE69532013T2 (de) 2004-07-08
RU2145609C1 (ru) 2000-02-20
DE69533004D1 (de) 2004-06-09
ATE266042T1 (de) 2004-05-15
EP0667353A1 (en) 1995-08-16
DE69533004T2 (de) 2005-04-07
PT667353E (pt) 2004-03-31
JPH07258289A (ja) 1995-10-09
ATE248856T1 (de) 2003-09-15
PT1016670E (pt) 2003-12-31
HUT68715A (en) 1995-07-28
CO4600679A1 (es) 1998-05-08
DK1031576T3 (da) 2004-08-16
EP0667353B1 (en) 2003-10-29
AU1138995A (en) 1995-08-10
PT1031576E (pt) 2004-08-31
ES2210274T3 (es) 2004-07-01
IL112457A0 (en) 1995-03-30
DE69531709T2 (de) 2004-07-15
EG25884A (en) 2012-09-24
FI117096B (fi) 2006-06-15
EP1016670A1 (en) 2000-07-05
US5843889A (en) 1998-12-01
CZ18495A3 (en) 1995-08-16
ES2204444T3 (es) 2004-05-01
FI950374A0 (fi) 1995-01-27
CA2141106C (en) 2007-01-23
MY128335A (en) 2007-01-31
DE69531709D1 (de) 2003-10-09
FI117097B (fi) 2006-06-15
HU9500230D0 (en) 1995-03-28
TW457248B (en) 2001-10-01
FI950374A (fi) 1995-07-29
HU225164B1 (en) 2006-07-28
PL306976A1 (en) 1995-08-07
CZ292921B6 (cs) 2004-01-14
FI20050512A (fi) 2005-05-13
NZ270387A (en) 1996-11-26
JP3756539B2 (ja) 2006-03-15
BR9500365A (pt) 1995-10-17
SG52719A1 (en) 1998-09-28
NO950298L (no) 1995-07-31
KR100388867B1 (ko) 2003-10-08
RU95101039A (ru) 1996-10-27
CZ292895B6 (cs) 2003-12-17
NO950298D0 (no) 1995-01-26
PL180961B1 (pl) 2001-05-31

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