SG69290G - Pleuromutilin derivatives,process for their preparation and their use - Google Patents

Pleuromutilin derivatives,process for their preparation and their use

Info

Publication number
SG69290G
SG69290G SG692/90A SG69290A SG69290G SG 69290 G SG69290 G SG 69290G SG 692/90 A SG692/90 A SG 692/90A SG 69290 A SG69290 A SG 69290A SG 69290 G SG69290 G SG 69290G
Authority
SG
Singapore
Prior art keywords
preparation
pleuromutilin derivatives
pleuromutilin
derivatives
Prior art date
Application number
SG692/90A
Other languages
English (en)
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19843405632 external-priority patent/DE3405632A1/de
Priority claimed from DE19843413708 external-priority patent/DE3413708A1/de
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of SG69290G publication Critical patent/SG69290G/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Fodder In General (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Peptides Or Proteins (AREA)
SG692/90A 1984-02-17 1990-08-22 Pleuromutilin derivatives,process for their preparation and their use SG69290G (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843405632 DE3405632A1 (de) 1984-02-17 1984-02-17 Neue pleuromutilinderivate, verfahren zu ihrer herstellung und ihre verwendung
DE19843413708 DE3413708A1 (de) 1984-04-12 1984-04-12 Neue pleuromutilinderivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
SG69290G true SG69290G (en) 1990-11-23

Family

ID=25818547

Family Applications (1)

Application Number Title Priority Date Filing Date
SG692/90A SG69290G (en) 1984-02-17 1990-08-22 Pleuromutilin derivatives,process for their preparation and their use

Country Status (21)

Country Link
US (1) US4675330A (xx)
EP (1) EP0153277B1 (xx)
JP (1) JPH068278B2 (xx)
KR (1) KR920001990B1 (xx)
AU (1) AU585209B2 (xx)
CA (1) CA1249281A (xx)
CY (1) CY1565A (xx)
DE (1) DE3560511D1 (xx)
DK (1) DK164664C (xx)
ES (1) ES8606262A1 (xx)
FI (1) FI90414C (xx)
GR (1) GR850415B (xx)
HK (1) HK103690A (xx)
HU (1) HU194819B (xx)
IE (1) IE58232B1 (xx)
IL (1) IL74355A (xx)
MY (1) MY102919A (xx)
NZ (1) NZ211131A (xx)
PH (1) PH21588A (xx)
PL (1) PL145848B1 (xx)
SG (1) SG69290G (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT392272B (de) * 1989-10-03 1991-02-25 Biochemie Gmbh Verfahren zur herstellung eines pleuromutilinderivats und seiner saeureadditionssalze
HU208115B (en) * 1989-10-03 1993-08-30 Biochemie Gmbh New process for producting pleuromutilin derivatives
AT400674B (de) * 1991-07-24 1996-02-26 Biochemie Gmbh Pharmazeutische pleuromutilin-zubereitung
AT397654B (de) * 1992-05-04 1994-06-27 Biochemie Gmbh Neue pleuromutilinderivate, ihre verwendung und verfahren zu ihrer herstellung
NO331772B1 (no) * 1996-07-04 2012-03-26 Biochemie Gmbh Veterinaermedisinsk anvendelse av et pleuromutilinderivat
KR100516418B1 (ko) * 1996-07-04 2005-12-20 바이오케미 게젤샤프트 엠베하 플루로뮤틸린유도체의수의학적용도
GB9614017D0 (en) * 1996-07-04 1996-09-04 Biochemie Gmbh Organic compounds
UY25225A1 (es) * 1997-10-29 2000-12-29 Smithkline Beecham Plc Derivados de pleuromutilina utiles como agentes antimicrobianos
GB9918037D0 (en) * 1999-07-30 1999-09-29 Biochemie Gmbh Organic compounds
TWI260220B (en) * 1999-11-22 2006-08-21 Novartis Ag A pharmaceutical composition for the transdermal treatment of bacterial infections in animals
GB0017031D0 (en) * 2000-07-11 2000-08-30 Biochemie Gmbh Antimicrobials
PE20020676A1 (es) * 2000-09-13 2002-08-27 Biochemie Gmbh Compuestos de mutilina como antibacterianos
CO5390081A1 (es) 2001-11-28 2004-04-30 Novartis Ag Compuestos organicos
US20040116510A1 (en) * 2002-03-05 2004-06-17 Nichtberger Steven A. Antihypertensive agent and cholesterol absorption inhibitor combination therapy
GB0209262D0 (en) * 2002-04-23 2002-06-05 Biochemie Gmbh Organic compounds
GB0308114D0 (en) * 2003-04-08 2003-05-14 Glaxo Group Ltd Novel compounds
EP1686115A1 (de) * 2005-01-26 2006-08-02 Novartis AG Organische Säureadditionssalze von Valnemulin
GB0504314D0 (en) * 2005-03-02 2005-04-06 Glaxo Group Ltd Novel polymorph
CN101880252B (zh) * 2010-06-29 2013-01-23 金河生物科技股份有限公司 盐酸沃尼妙林的制备方法
CN102229580B (zh) * 2011-05-12 2014-02-26 南通大学 新型截短侧耳素衍生物、其制备方法及其医药用途
CN102344397B (zh) * 2011-08-23 2013-09-04 浙江升华拜克生物股份有限公司 一种伐奈莫林盐酸盐的提纯方法
CN102424660B (zh) * 2011-08-25 2013-11-27 浙江升华拜克生物股份有限公司 一种伐奈莫林盐酸盐的低温起泡干燥法及其干燥品
CN102675173B (zh) * 2012-04-28 2013-12-11 武汉回盛生物科技有限公司 一种盐酸沃尼妙林的化学合成方法
CN103193692A (zh) * 2013-04-23 2013-07-10 河北科技大学 一种沃尼妙林及其盐酸盐的制备
CN104311464A (zh) * 2014-09-15 2015-01-28 河北威远动物药业有限公司 一种兽用沃尼妙林的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4060542A (en) * 1969-07-25 1977-11-29 Biochemie Gesellschaft M.B.H. 14-Desoxy-14 thiocyanato-acetoxy-mutilin
US3919290A (en) * 1972-10-03 1975-11-11 Sandoz Ltd Substituted 14-desoxy-mutilins
US4086359A (en) * 1975-09-30 1978-04-25 E. R. Squibb & Sons, Inc. Derivatives of pleuromutilin and compositions
CH619450A5 (xx) * 1976-01-15 1980-09-30 Sandoz Ag
JPS54160358A (en) * 1978-06-06 1979-12-19 Sandoz Ag Improvement for organic compound
GB2072012B (en) * 1980-03-14 1984-07-25 Squibb & Sons Inc Veterinary compositions containing pleuromutilin derivatives
FR2526019A1 (fr) * 1982-04-28 1983-11-04 Sandoz Sa Nouveaux derives de la pleuromutiline, leur preparation et leur utilisation comme medicaments

Also Published As

Publication number Publication date
IE58232B1 (en) 1993-08-11
DE3560511D1 (en) 1987-10-01
NZ211131A (en) 1988-08-30
PL251972A1 (en) 1985-12-03
AU585209B2 (en) 1989-06-15
CA1249281A (en) 1989-01-24
HK103690A (en) 1990-12-21
DK72885D0 (da) 1985-02-15
IL74355A (en) 1988-04-29
EP0153277B1 (de) 1987-08-26
EP0153277A2 (de) 1985-08-28
ES540464A0 (es) 1986-04-16
PH21588A (en) 1987-12-11
DK164664C (da) 1992-12-21
EP0153277A3 (en) 1985-09-25
ES8606262A1 (es) 1986-04-16
HUT39155A (en) 1986-08-28
DK72885A (da) 1985-08-18
KR920001990B1 (ko) 1992-03-09
KR850006938A (ko) 1985-10-25
FI850654A0 (fi) 1985-02-15
FI90414B (fi) 1993-10-29
FI90414C (fi) 1994-02-10
IL74355A0 (en) 1985-05-31
PL145848B1 (en) 1988-11-30
US4675330A (en) 1987-06-23
IE850375L (en) 1985-08-17
DK164664B (da) 1992-07-27
HU194819B (en) 1988-03-28
CY1565A (en) 1991-05-17
FI850654L (fi) 1985-08-18
JPH068278B2 (ja) 1994-02-02
JPS60199870A (ja) 1985-10-09
MY102919A (en) 1993-03-31
AU3877385A (en) 1985-09-12
GR850415B (xx) 1985-06-18

Similar Documents

Publication Publication Date Title
DE3560511D1 (en) Pleuromutilin derivatives, process for their preparation and their use
EP0187620A3 (en) Pyrrolo-pyrroles, process for their preparation and use
EP0228612A3 (en) A derivative of alpha, alpha-trehalose and a process for preparing the same
ZA865263B (en) Poly-4-aminopyrrole-2-carboxamido derivatives and process for their preparation
EP0186628A3 (en) Pentaerythritdiphosphites, process for their preparation and their use as stabilizers
DE3568435D1 (en) 2-acetoacetylglycerol derivatives, their production and use
GB2178036B (en) Poly-4-aminopyrrole-2-carboxamido derivatives and process for their preparation
EP0221781A3 (en) Benzylamine derivatives, process for production thereof, and use thereof
ZA854287B (en) Dialkoxypyridines,process for their preparation,their use and medicaments containing them
IL74133A0 (en) Azolyl-aryl-alkanol derivatives,processes for their preparation and their use
DE3463041D1 (en) Tributylphenolether-glycidyl-sulphonates, process for their preparation and their use
EP0158888A3 (en) Disazo compounds, process for their preparation and their use
DE3567638D1 (en) 2,4-dichloro-3-alkyl-6-nitrophenols and process for their preparation
DE3573771D1 (en) 2-decalyl-2-cyclohexyl derivatives of propane, process for their preparation, and their use
EP0121081A3 (en) Azolylmethylcycloalkanes, process for their preparation and their therapeutical use
ZA846580B (en) 16-fluoro-16,17-didehydro-prostanoids and process for their preparation
DE3367598D1 (en) 14-amino-steroid derivatives, their therapeutical use and process for their preparation
CS382191A3 (en) Benzoxazol- and benzothiazolamine derivatives, process of their preparation and pharmaceuticals based thereon
ZA851190B (en) Pleuromutilin derivatives,process for their preparation and their use
DE3661830D1 (en) 2,4-dichlorothiazole derivatives and process for their preparation
DE3561058D1 (en) Hydroxy-thia-alcanes, process for their preparation and their uses
DE3662261D1 (en) Dihalogeno-2,2-vinyl-halogeno formates, process for their preparation and their uses
HUT37591A (en) Process for preparing /1,3-dioxi-1,3-propane-diil/-diimino/ -bis-benzoic acid and its derivatives
EP0211303A3 (en) 2-acyl-5-methyl furans, process for their preparation and their use
ZA856735B (en) Novel pseudooligosaccharides with an alpha-glucosidase-inhibiting action,a process for their preparation,their use and pharmaceutical products