SG55006A1 - Crystalline anhydrous mycophenolate mofetil and intravenous formulation thereof - Google Patents

Crystalline anhydrous mycophenolate mofetil and intravenous formulation thereof

Info

Publication number
SG55006A1
SG55006A1 SG1996001679A SG1996001679A SG55006A1 SG 55006 A1 SG55006 A1 SG 55006A1 SG 1996001679 A SG1996001679 A SG 1996001679A SG 1996001679 A SG1996001679 A SG 1996001679A SG 55006 A1 SG55006 A1 SG 55006A1
Authority
SG
Singapore
Prior art keywords
mycophenolate mofetil
crystalline anhydrous
intravenous formulation
anhydrous mycophenolate
crystalline
Prior art date
Application number
SG1996001679A
Other languages
English (en)
Inventor
Roger Cherng Fu
De-Mei Leung
Jeffery S Fleitman
Michele C Rizzolio
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of SG55006A1 publication Critical patent/SG55006A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
SG1996001679A 1993-09-15 1994-09-12 Crystalline anhydrous mycophenolate mofetil and intravenous formulation thereof SG55006A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12184193A 1993-09-15 1993-09-15

Publications (1)

Publication Number Publication Date
SG55006A1 true SG55006A1 (en) 1998-12-21

Family

ID=22399119

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996001679A SG55006A1 (en) 1993-09-15 1994-09-12 Crystalline anhydrous mycophenolate mofetil and intravenous formulation thereof

Country Status (32)

Country Link
US (2) US5543408A (zh)
EP (1) EP0724581B1 (zh)
JP (1) JP3411038B2 (zh)
KR (1) KR100349772B1 (zh)
CN (1) CN1060770C (zh)
AT (1) ATE173475T1 (zh)
AU (1) AU677435B2 (zh)
BR (1) BR9407469A (zh)
CA (1) CA2171836C (zh)
CZ (1) CZ292423B6 (zh)
DE (1) DE69414720T2 (zh)
DK (1) DK0724581T3 (zh)
ES (1) ES2123831T3 (zh)
FI (1) FI119639B (zh)
HK (1) HK1012624A1 (zh)
HU (1) HU217300B (zh)
IL (1) IL110970A (zh)
LT (1) LT4052B (zh)
LV (1) LV11326B (zh)
MX (1) MXPA94007099A (zh)
NO (1) NO314727B1 (zh)
NZ (1) NZ273801A (zh)
PH (1) PH30685A (zh)
PL (1) PL178522B1 (zh)
RO (2) RO118075B1 (zh)
RU (1) RU2132849C1 (zh)
SG (1) SG55006A1 (zh)
SI (1) SI9420052B (zh)
TW (1) TW370527B (zh)
UA (1) UA49797C2 (zh)
WO (1) WO1995007902A1 (zh)
ZA (1) ZA947088B (zh)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9512854D0 (en) * 1995-06-23 1995-08-23 Wellcome Found Novel formulation
IN188985B (zh) 1998-12-09 2002-11-30 Biocon Ltd
GB0301259D0 (en) 2003-01-20 2003-02-19 Novartis Ag Organic compounds
GB0307553D0 (en) * 2003-04-01 2003-05-07 Novartis Ag Organic compounds
US20050187170A1 (en) * 2003-06-16 2005-08-25 Biocryst Pharmaceuticals, Inc. Enhancing the efficiency of RNA polymerase inhibitors by using inosine monophosphate dehydrogenase inhibitors
ATE402157T1 (de) * 2003-09-11 2008-08-15 Sandoz Ag Verfahren zur herstellung von mycophenolatmofetil
JP2007532585A (ja) * 2004-04-26 2007-11-15 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ ミコフェノール酸及びそのエステル誘導体の調製方法
EP1740563A2 (en) * 2004-04-27 2007-01-10 Teva Gyógyszergyár Zártköruen Muködo Részvenytarsaság Mycophenolate mofetil impurity
EP1768662A2 (en) 2004-06-24 2007-04-04 Novartis Vaccines and Diagnostics, Inc. Small molecule immunopotentiators and assays for their detection
WO2006012379A2 (en) * 2004-07-20 2006-02-02 Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg Processes for preparation of crystalline mycophenolate sodium
CN100383520C (zh) * 2004-09-20 2008-04-23 复旦大学 一种测定人血浆中霉酚酸及其代谢物的方法
EP1917010A2 (en) * 2005-02-08 2008-05-07 Aspreva Pharmaceuticals SA Compositions and methods for treating vascular, autoimmune and inflammatory diseases
WO2006086498A2 (en) * 2005-02-08 2006-08-17 Aspreva Pharmaceuticals Sa Treatment of vascular, autoimmune and inflammatory diseases using low dosages of impdh inhibitors
US20080280977A1 (en) * 2005-04-26 2008-11-13 Sandor Molnar Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid
SI2032521T1 (sl) 2006-06-27 2010-02-26 Sandoz Ag Nov postopek za pripravo soli
CN101953807A (zh) * 2010-10-09 2011-01-26 山西普德药业有限公司 一种注射用吗替麦考酚酯冻干粉针剂及其制备方法
DK2970101T3 (en) 2013-03-14 2018-08-20 Alkermes Pharma Ireland Ltd PRO-DRUGS OF FUMARATES AND THEIR USE IN TREATING DIFFERENT DISEASES
US8669281B1 (en) 2013-03-14 2014-03-11 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
US9168246B2 (en) 2013-06-27 2015-10-27 Veloxis Pharmaceutical A/S Regimen for suppressing organ rejection
CA2940845C (en) 2014-02-24 2019-09-24 Alkermes Pharma Ireland Limited Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases
US11918684B2 (en) 2017-03-13 2024-03-05 Liqmeds Worldwide Limited Pharmaceutical composition of oral suspension of immunosuppressive agents
EP4301380A1 (en) 2021-03-03 2024-01-10 Sana Biotechnology, Inc. Immunosuppressive therapies for use with cardiomyocyte cell therapies, and associated methods and compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328213A (en) * 1979-11-28 1982-05-04 Schering Corporation Stable injectable labetalol formulation
US4478829A (en) * 1983-04-28 1984-10-23 Armour Pharmaceutical Company Pharmaceutical preparation containing purified fibronectin
US4753935A (en) * 1987-01-30 1988-06-28 Syntex (U.S.A.) Inc. Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions

Also Published As

Publication number Publication date
PH30685A (en) 1997-09-16
FI961169A (fi) 1996-03-13
IL110970A0 (en) 1994-11-28
DE69414720T2 (de) 1999-04-08
CA2171836A1 (en) 1995-03-23
ATE173475T1 (de) 1998-12-15
FI119639B (fi) 2009-01-30
KR100349772B1 (ko) 2002-12-28
RO118427B1 (ro) 2003-05-30
JP3411038B2 (ja) 2003-05-26
CZ292423B6 (cs) 2003-09-17
RU2132849C1 (ru) 1999-07-10
DE69414720D1 (de) 1998-12-24
LV11326B (en) 1996-10-20
NO961075L (no) 1996-03-15
HUT75119A (en) 1997-04-28
CZ78896A3 (en) 1996-10-16
SI9420052B (sl) 2004-02-29
HU217300B (hu) 1999-12-28
DK0724581T3 (da) 1999-08-02
FI961169A0 (fi) 1996-03-13
RO118075B1 (ro) 2003-01-30
IL110970A (en) 1999-01-26
LT4052B (en) 1996-10-25
TW370527B (en) 1999-09-21
EP0724581A1 (en) 1996-08-07
WO1995007902A1 (en) 1995-03-23
UA49797C2 (uk) 2002-10-15
NO314727B1 (no) 2003-05-12
ES2123831T3 (es) 1999-01-16
CN1131420A (zh) 1996-09-18
SI9420052A (en) 1996-12-31
CA2171836C (en) 2006-11-14
JPH09502721A (ja) 1997-03-18
BR9407469A (pt) 1996-11-12
NZ273801A (en) 1997-10-24
MXPA94007099A (es) 2004-01-23
LT96028A (en) 1996-08-26
US5545637A (en) 1996-08-13
CN1060770C (zh) 2001-01-17
US5543408A (en) 1996-08-06
HU9600652D0 (en) 1996-05-28
PL178522B1 (pl) 2000-05-31
AU677435B2 (en) 1997-04-24
ZA947088B (en) 1996-03-14
EP0724581B1 (en) 1998-11-18
NO961075D0 (no) 1996-03-15
HK1012624A1 (en) 1999-08-06
AU7723894A (en) 1995-04-03
PL313480A1 (en) 1996-07-08
LV11326A (lv) 1996-06-20

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