ES2123831T3 - Micofenolato de mofetilo cristalino anhidro y formulacion intravenosa del mismo. - Google Patents
Micofenolato de mofetilo cristalino anhidro y formulacion intravenosa del mismo.Info
- Publication number
- ES2123831T3 ES2123831T3 ES94928054T ES94928054T ES2123831T3 ES 2123831 T3 ES2123831 T3 ES 2123831T3 ES 94928054 T ES94928054 T ES 94928054T ES 94928054 T ES94928054 T ES 94928054T ES 2123831 T3 ES2123831 T3 ES 2123831T3
- Authority
- ES
- Spain
- Prior art keywords
- mycophenolate
- mophyllum
- anhydrous crystalline
- intravenous formulation
- intravenous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
EL COMPUESTO ANHIDRIDO CRISTALINO DE FORMULA (I) EN DONDE EL COMPUESTO ES COMPLEXADO COMO UNA SAL CON UN ANION SELECCIONADO DEL GRUPO QUE CONSTA DE CLORO, SULFATO, FOSFATO Y ACETATO, EN PARTICULAR LA SAL DE HIDROCLORURO, Y COMPOSICIONES, FORMULACIONES INTRAVENOSAS Y UN GRUPO DE LAS MISMAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12184193A | 1993-09-15 | 1993-09-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2123831T3 true ES2123831T3 (es) | 1999-01-16 |
Family
ID=22399119
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94928054T Expired - Lifetime ES2123831T3 (es) | 1993-09-15 | 1994-09-12 | Micofenolato de mofetilo cristalino anhidro y formulacion intravenosa del mismo. |
Country Status (32)
Country | Link |
---|---|
US (2) | US5543408A (es) |
EP (1) | EP0724581B1 (es) |
JP (1) | JP3411038B2 (es) |
KR (1) | KR100349772B1 (es) |
CN (1) | CN1060770C (es) |
AT (1) | ATE173475T1 (es) |
AU (1) | AU677435B2 (es) |
BR (1) | BR9407469A (es) |
CA (1) | CA2171836C (es) |
CZ (1) | CZ292423B6 (es) |
DE (1) | DE69414720T2 (es) |
DK (1) | DK0724581T3 (es) |
ES (1) | ES2123831T3 (es) |
FI (1) | FI119639B (es) |
HK (1) | HK1012624A1 (es) |
HU (1) | HU217300B (es) |
IL (1) | IL110970A (es) |
LT (1) | LT4052B (es) |
LV (1) | LV11326B (es) |
MX (1) | MXPA94007099A (es) |
NO (1) | NO314727B1 (es) |
NZ (1) | NZ273801A (es) |
PH (1) | PH30685A (es) |
PL (1) | PL178522B1 (es) |
RO (2) | RO118075B1 (es) |
RU (1) | RU2132849C1 (es) |
SG (1) | SG55006A1 (es) |
SI (1) | SI9420052B (es) |
TW (1) | TW370527B (es) |
UA (1) | UA49797C2 (es) |
WO (1) | WO1995007902A1 (es) |
ZA (1) | ZA947088B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9512854D0 (en) * | 1995-06-23 | 1995-08-23 | Wellcome Found | Novel formulation |
IN188985B (es) * | 1998-12-09 | 2002-11-30 | Biocon Ltd | |
GB0301259D0 (en) | 2003-01-20 | 2003-02-19 | Novartis Ag | Organic compounds |
GB0307553D0 (en) * | 2003-04-01 | 2003-05-07 | Novartis Ag | Organic compounds |
US20050187170A1 (en) * | 2003-06-16 | 2005-08-25 | Biocryst Pharmaceuticals, Inc. | Enhancing the efficiency of RNA polymerase inhibitors by using inosine monophosphate dehydrogenase inhibitors |
ES2308226T3 (es) * | 2003-09-11 | 2008-12-01 | Sandoz Ag | Proceso para la produccion de micofenolato mofetil. |
EP1740564A2 (en) * | 2004-04-26 | 2007-01-10 | Teva Gyógyszergyár Zártköruen Muködo Részvenytarsaság | Process for preparation of mycophenolic acid and ester derivatives thereof |
MXPA06005658A (es) * | 2004-04-27 | 2007-04-10 | Teva Gyogyszergyar Zartkoruen | Proceso para preparacion de micofenolato mofetil, y otros esteres de acido micofenolico. |
CA2571710A1 (en) | 2004-06-24 | 2006-11-02 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
CN101052631A (zh) * | 2004-07-20 | 2007-10-10 | 特瓦药厂私人有限公司 | 结晶霉酚酸钠 |
CN100383520C (zh) * | 2004-09-20 | 2008-04-23 | 复旦大学 | 一种测定人血浆中霉酚酸及其代谢物的方法 |
US20060235009A1 (en) * | 2005-02-08 | 2006-10-19 | Richard Glickman | Treatment of vascular, autoimmune and inflammatory diseases using low dosages of IMPDH inhibitors |
US20060235070A1 (en) * | 2005-02-08 | 2006-10-19 | Hayden Michael R | Compositions and methods for treating vascular, autoimmune, and inflammatory diseases |
US20080281111A1 (en) * | 2005-04-26 | 2008-11-13 | Sandor Molnar | Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid |
EP2032521B1 (en) | 2006-06-27 | 2009-10-28 | Sandoz AG | New method for salt preparation |
CN101953807A (zh) * | 2010-10-09 | 2011-01-26 | 山西普德药业有限公司 | 一种注射用吗替麦考酚酯冻干粉针剂及其制备方法 |
US8669281B1 (en) | 2013-03-14 | 2014-03-11 | Alkermes Pharma Ireland Limited | Prodrugs of fumarates and their use in treating various diseases |
PT2970101T (pt) | 2013-03-14 | 2018-10-04 | Alkermes Pharma Ireland Ltd | Pró-fármacos de fumaratos e seu uso no tratamento de várias doenças |
US9168246B2 (en) | 2013-06-27 | 2015-10-27 | Veloxis Pharmaceutical A/S | Regimen for suppressing organ rejection |
NZ723269A (en) | 2014-02-24 | 2017-04-28 | Alkermes Pharma Ireland Ltd | Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases |
US11918684B2 (en) | 2017-03-13 | 2024-03-05 | Liqmeds Worldwide Limited | Pharmaceutical composition of oral suspension of immunosuppressive agents |
CA3212370A1 (en) | 2021-03-03 | 2022-09-09 | Sana Biotechnology, Inc. | Immunosuppressive therapies for use with cardiomyocyte cell therapies, and associated methods and compositions |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4328213A (en) * | 1979-11-28 | 1982-05-04 | Schering Corporation | Stable injectable labetalol formulation |
US4478829A (en) * | 1983-04-28 | 1984-10-23 | Armour Pharmaceutical Company | Pharmaceutical preparation containing purified fibronectin |
US4753935A (en) | 1987-01-30 | 1988-06-28 | Syntex (U.S.A.) Inc. | Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions |
-
1994
- 1994-09-12 JP JP50925595A patent/JP3411038B2/ja not_active Expired - Lifetime
- 1994-09-12 DE DE69414720T patent/DE69414720T2/de not_active Expired - Lifetime
- 1994-09-12 CZ CZ1996788A patent/CZ292423B6/cs not_active IP Right Cessation
- 1994-09-12 RO RO96-00567A patent/RO118075B1/ro unknown
- 1994-09-12 SG SG1996001679A patent/SG55006A1/en unknown
- 1994-09-12 ES ES94928054T patent/ES2123831T3/es not_active Expired - Lifetime
- 1994-09-12 SI SI9420052A patent/SI9420052B/sl unknown
- 1994-09-12 BR BR9407469A patent/BR9407469A/pt not_active Application Discontinuation
- 1994-09-12 HU HU9600652A patent/HU217300B/hu unknown
- 1994-09-12 WO PCT/US1994/010142 patent/WO1995007902A1/en active IP Right Grant
- 1994-09-12 NZ NZ273801A patent/NZ273801A/en not_active IP Right Cessation
- 1994-09-12 CN CN94193413A patent/CN1060770C/zh not_active Expired - Lifetime
- 1994-09-12 AT AT94928054T patent/ATE173475T1/de active
- 1994-09-12 PL PL94313480A patent/PL178522B1/pl unknown
- 1994-09-12 AU AU77238/94A patent/AU677435B2/en not_active Expired
- 1994-09-12 RU RU96107396A patent/RU2132849C1/ru active
- 1994-09-12 CA CA002171836A patent/CA2171836C/en not_active Expired - Lifetime
- 1994-09-12 DK DK94928054T patent/DK0724581T3/da active
- 1994-09-12 KR KR1019960701354A patent/KR100349772B1/ko not_active IP Right Cessation
- 1994-09-12 EP EP94928054A patent/EP0724581B1/en not_active Expired - Lifetime
- 1994-09-12 RO ROA200201154A patent/RO118427B1/ro unknown
- 1994-09-14 TW TW083108484A patent/TW370527B/zh not_active IP Right Cessation
- 1994-09-14 IL IL11097094A patent/IL110970A/en not_active IP Right Cessation
- 1994-09-14 ZA ZA947088A patent/ZA947088B/xx unknown
- 1994-09-14 PH PH48985A patent/PH30685A/en unknown
- 1994-12-05 US US08/349,236 patent/US5543408A/en not_active Expired - Lifetime
- 1994-12-09 UA UA96031026A patent/UA49797C2/uk unknown
-
1995
- 1995-06-02 US US08/459,991 patent/US5545637A/en not_active Expired - Lifetime
-
1996
- 1996-03-13 FI FI961169A patent/FI119639B/fi not_active IP Right Cessation
- 1996-03-15 NO NO19961075A patent/NO314727B1/no not_active IP Right Cessation
- 1996-03-15 LT LT96-028A patent/LT4052B/lt not_active IP Right Cessation
- 1996-03-15 LV LVP-96-85A patent/LV11326B/en unknown
-
1997
- 1997-12-05 MX MXPA94007099A patent/MXPA94007099A/es active IP Right Grant
-
1998
- 1998-12-17 HK HK98113833A patent/HK1012624A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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