IN188985B - - Google Patents

Info

Publication number
IN188985B
IN188985B IN2754MA1998A IN188985B IN 188985 B IN188985 B IN 188985B IN 2754MA1998 A IN2754MA1998 A IN 2754MA1998A IN 188985 B IN188985 B IN 188985B
Authority
IN
India
Prior art keywords
mycophenolic acid
mofetil
mycophenolate
morpholino ethanol
mycophenblate
Prior art date
Application number
Other languages
English (en)
Inventor
Sircar Dr Aninday
Suryanarayan Shrikumar
Original Assignee
Biocon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Ltd filed Critical Biocon Ltd
Priority to IN2754MA1998 priority Critical patent/IN188985B/en
Priority to DE69928002T priority patent/DE69928002T2/de
Priority to AT99964770T priority patent/ATE307892T1/de
Priority to DK99964770T priority patent/DK1137795T3/da
Priority to ES99964770T priority patent/ES2252995T3/es
Priority to CA2354554A priority patent/CA2354554C/en
Priority to PCT/IN1999/000070 priority patent/WO2000034503A2/en
Priority to US09/857,579 priority patent/US6709846B1/en
Priority to EP99964770A priority patent/EP1137795B1/en
Priority to AU30732/00A priority patent/AU3073200A/en
Publication of IN188985B publication Critical patent/IN188985B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/162—Heterorings having oxygen atoms as the only ring heteroatoms, e.g. Lasalocid

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IN2754MA1998 1998-12-09 1998-12-09 IN188985B (zh)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IN2754MA1998 IN188985B (zh) 1998-12-09 1998-12-09
DE69928002T DE69928002T2 (de) 1998-12-09 1999-12-09 Verfahren zur herstellung von mycophenolatestern
AT99964770T ATE307892T1 (de) 1998-12-09 1999-12-09 Verfahren zur herstellung von mycophenolatestern
DK99964770T DK1137795T3 (da) 1998-12-09 1999-12-09 Fremgangsmåder til fremstilling af estere af mycophenolat
ES99964770T ES2252995T3 (es) 1998-12-09 1999-12-09 Procedimientos de produccion de esteres de micofenolato.
CA2354554A CA2354554C (en) 1998-12-09 1999-12-09 Methods of producing esters of mycophenolate
PCT/IN1999/000070 WO2000034503A2 (en) 1998-12-09 1999-12-09 Methods of producing esters of mycophenolate
US09/857,579 US6709846B1 (en) 1998-12-09 1999-12-09 Methods of producing esters of mycophenolate
EP99964770A EP1137795B1 (en) 1998-12-09 1999-12-09 Methods of producing esters of mycophenolate
AU30732/00A AU3073200A (en) 1998-12-09 1999-12-09 Methods of producing esters of mycophenolate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN2754MA1998 IN188985B (zh) 1998-12-09 1998-12-09

Publications (1)

Publication Number Publication Date
IN188985B true IN188985B (zh) 2002-11-30

Family

ID=11096895

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2754MA1998 IN188985B (zh) 1998-12-09 1998-12-09

Country Status (10)

Country Link
US (1) US6709846B1 (zh)
EP (1) EP1137795B1 (zh)
AT (1) ATE307892T1 (zh)
AU (1) AU3073200A (zh)
CA (1) CA2354554C (zh)
DE (1) DE69928002T2 (zh)
DK (1) DK1137795T3 (zh)
ES (1) ES2252995T3 (zh)
IN (1) IN188985B (zh)
WO (1) WO2000034503A2 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003042393A1 (en) * 2001-11-16 2003-05-22 Biocon Limited Enzymatic preparation of mycophenolate mofetil
TWI221414B (en) * 2003-02-21 2004-10-01 Chunghwa Chemical Synthesis & Method of making mycophenolate mofetil using transesterification
ATE402157T1 (de) * 2003-09-11 2008-08-15 Sandoz Ag Verfahren zur herstellung von mycophenolatmofetil
JP2007532585A (ja) * 2004-04-26 2007-11-15 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ ミコフェノール酸及びそのエステル誘導体の調製方法
EP1740563A2 (en) * 2004-04-27 2007-01-10 Teva Gyógyszergyár Zártköruen Muködo Részvenytarsaság Mycophenolate mofetil impurity
WO2006012379A2 (en) * 2004-07-20 2006-02-02 Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg Processes for preparation of crystalline mycophenolate sodium
ITMI20041703A1 (it) * 2004-09-03 2004-12-03 Poli Ind Chimica Spa Metodo di preparazione del mofetil micofenolato per transesterificazione enzimatica
US20080280977A1 (en) * 2005-04-26 2008-11-13 Sandor Molnar Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid
CN1328272C (zh) * 2005-08-22 2007-07-25 鲁南制药集团股份有限公司 一种工业化生产霉酚酸莫啡酯的方法
CN100402516C (zh) * 2005-10-18 2008-07-16 深圳市东阳光实业发展有限公司 一种霉酚酸莫啡酯的制备方法
US20080188653A1 (en) 2007-02-04 2008-08-07 Formosa Laboratories, Inc. Process for Preparation of Mycophenolate Mofetil
CN100484930C (zh) * 2007-03-16 2009-05-06 重庆大新药业股份有限公司 一种吗替麦考酚酯的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753935A (en) 1987-01-30 1988-06-28 Syntex (U.S.A.) Inc. Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions
US5247083A (en) * 1992-07-10 1993-09-21 Syntex (U.S.A.) Inc. Direct esterification of mycophenolic acid
SG55006A1 (en) 1993-09-15 1998-12-21 Syntex Inc Crystalline anhydrous mycophenolate mofetil and intravenous formulation thereof

Also Published As

Publication number Publication date
EP1137795A2 (en) 2001-10-04
ATE307892T1 (de) 2005-11-15
DE69928002D1 (de) 2005-12-01
DE69928002T2 (de) 2006-07-27
CA2354554C (en) 2010-05-25
CA2354554A1 (en) 2000-06-15
ES2252995T3 (es) 2006-05-16
WO2000034503A3 (en) 2000-08-17
US6709846B1 (en) 2004-03-23
WO2000034503A2 (en) 2000-06-15
DK1137795T3 (da) 2006-03-20
EP1137795B1 (en) 2005-10-26
AU3073200A (en) 2000-06-26

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