CN100484930C - 一种吗替麦考酚酯的制备方法 - Google Patents
一种吗替麦考酚酯的制备方法 Download PDFInfo
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- CN100484930C CN100484930C CNB2007100865976A CN200710086597A CN100484930C CN 100484930 C CN100484930 C CN 100484930C CN B2007100865976 A CNB2007100865976 A CN B2007100865976A CN 200710086597 A CN200710086597 A CN 200710086597A CN 100484930 C CN100484930 C CN 100484930C
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- mycophenolic acid
- mycophenolate mofetile
- mycophenolate
- mofetile
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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CNB2007100865976A CN100484930C (zh) | 2007-03-16 | 2007-03-16 | 一种吗替麦考酚酯的制备方法 |
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CNB2007100865976A CN100484930C (zh) | 2007-03-16 | 2007-03-16 | 一种吗替麦考酚酯的制备方法 |
Publications (2)
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CN101037427A CN101037427A (zh) | 2007-09-19 |
CN100484930C true CN100484930C (zh) | 2009-05-06 |
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CNB2007100865976A Active CN100484930C (zh) | 2007-03-16 | 2007-03-16 | 一种吗替麦考酚酯的制备方法 |
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Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102351821A (zh) * | 2011-10-24 | 2012-02-15 | 福建和泉生物科技有限公司 | 一种采用陶瓷膜分离技术分离霉酚酸发酵液的方法 |
CN102924413B (zh) * | 2012-10-23 | 2014-12-31 | 福建科瑞药业有限公司 | 一种霉酚酸莫啡酯纯化脱色方法 |
CN106866595B (zh) * | 2017-03-04 | 2019-03-08 | 丽珠集团新北江制药股份有限公司 | 一种吗替麦考酚酯制备方法 |
CN113549040A (zh) * | 2020-04-23 | 2021-10-26 | 鲁南制药集团股份有限公司 | 一种吗替麦考酚酯杂质d的制备方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4753935A (en) * | 1987-01-30 | 1988-06-28 | Syntex (U.S.A.) Inc. | Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions |
US5247083A (en) * | 1992-07-10 | 1993-09-21 | Syntex (U.S.A.) Inc. | Direct esterification of mycophenolic acid |
US6709846B1 (en) * | 1998-12-09 | 2004-03-23 | Biocon India Limited | Methods of producing esters of mycophenolate |
CN1520411A (zh) * | 2001-06-08 | 2004-08-11 | ����˹��ҩ�﹫˾ | 霉酚酸莫啡酯的制备方法 |
CN1733749A (zh) * | 2005-08-22 | 2006-02-15 | 鲁南制药集团股份有限公司 | 一种工业化生产霉酚酸莫啡酯的方法 |
CN1772745A (zh) * | 2005-10-18 | 2006-05-17 | 深圳市东阳光实业发展有限公司 | 一种霉酚酸莫啡酯的制备方法 |
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2007
- 2007-03-16 CN CNB2007100865976A patent/CN100484930C/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4753935A (en) * | 1987-01-30 | 1988-06-28 | Syntex (U.S.A.) Inc. | Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions |
US5247083A (en) * | 1992-07-10 | 1993-09-21 | Syntex (U.S.A.) Inc. | Direct esterification of mycophenolic acid |
US6709846B1 (en) * | 1998-12-09 | 2004-03-23 | Biocon India Limited | Methods of producing esters of mycophenolate |
CN1520411A (zh) * | 2001-06-08 | 2004-08-11 | ����˹��ҩ�﹫˾ | 霉酚酸莫啡酯的制备方法 |
CN1733749A (zh) * | 2005-08-22 | 2006-02-15 | 鲁南制药集团股份有限公司 | 一种工业化生产霉酚酸莫啡酯的方法 |
CN1772745A (zh) * | 2005-10-18 | 2006-05-17 | 深圳市东阳光实业发展有限公司 | 一种霉酚酸莫啡酯的制备方法 |
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CN101037427A (zh) | 2007-09-19 |
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Effective date of registration: 20090918 Address after: No. 22, creative road, Beibei District, Chongqing, China: 400700 Patentee after: CHONGQING DAXIN PHARMACEUTICAL Co.,Ltd. Address before: No. 22, Beibei District, Chongqing, zip code: 400700 Co-patentee before: PEKING UNIVERSITY FOUNDER GROUP Co.,Ltd. Patentee before: CHONGQING DAXIN PHARMACEUTICAL Co.,Ltd. |
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Owner name: PKU HEAL THCARE CHONGQING DAXIN PHARMACEUTICAL CO. Free format text: FORMER NAME: PKU INTERNATIONAL HEALTHCARE GROUP CHONGQING DAXIN PHARMACEUTICAL CO., LTD. Owner name: PKU INTERNATIONAL HEALTHCARE GROUP CHONGQING DAXIN Free format text: FORMER NAME: CHONGQING DAXIN PHARMACEUTICAL CO., LTD. |
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Address after: 400000 No. 22, creative road, Beibei District, Chongqing Patentee after: CHONGQING DAXIN PHARMACEUTICAL Co.,Ltd. Address before: 400000 No. 22, creative road, Beibei District, Chongqing Patentee before: Peking University International Hospital Group Chongqing Daxin Pharmaceutical Co.,Ltd. Address after: 400000 No. 22, creative road, Beibei District, Chongqing Patentee after: Peking University International Hospital Group Chongqing Daxin Pharmaceutical Co.,Ltd. Address before: 400000 No. 22, creative road, Beibei District, Chongqing Patentee before: CHONGQING DAXIN PHARMACEUTICAL Co.,Ltd. |