SG47043A1 - Ionic molecular conjugates of biodegradeble polyesters and bioactive polypeptides - Google Patents

Ionic molecular conjugates of biodegradeble polyesters and bioactive polypeptides

Info

Publication number
SG47043A1
SG47043A1 SG1996004005A SG1996004005A SG47043A1 SG 47043 A1 SG47043 A1 SG 47043A1 SG 1996004005 A SG1996004005 A SG 1996004005A SG 1996004005 A SG1996004005 A SG 1996004005A SG 47043 A1 SG47043 A1 SG 47043A1
Authority
SG
Singapore
Prior art keywords
biodegradeble
polyesters
molecular conjugates
bioactive polypeptides
ionic molecular
Prior art date
Application number
SG1996004005A
Other languages
English (en)
Inventor
Shalaby SHALABY
Steven A Jackson
Jacques-Pierre Moreau
Original Assignee
Kinerton Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kinerton Ltd filed Critical Kinerton Ltd
Publication of SG47043A1 publication Critical patent/SG47043A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicinal Preparation (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SG1996004005A 1993-01-06 1994-01-05 Ionic molecular conjugates of biodegradeble polyesters and bioactive polypeptides SG47043A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE930005 1993-01-06
CNB941085236A CN1163260C (zh) 1993-01-06 1994-07-20 可生物降解聚酯和生物活性多肽的离子性分子轭合物

Publications (1)

Publication Number Publication Date
SG47043A1 true SG47043A1 (en) 1998-03-20

Family

ID=37075859

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996004005A SG47043A1 (en) 1993-01-06 1994-01-05 Ionic molecular conjugates of biodegradeble polyesters and bioactive polypeptides

Country Status (20)

Country Link
EP (1) EP0678018B1 (fr)
JP (1) JPH08505395A (fr)
CN (1) CN1163260C (fr)
AT (1) ATE236655T1 (fr)
AU (1) AU680650B2 (fr)
CA (1) CA2150574A1 (fr)
CZ (2) CZ293425B6 (fr)
DE (1) DE69432459T2 (fr)
DK (1) DK0678018T3 (fr)
ES (1) ES2196023T3 (fr)
FI (1) FI114898B (fr)
HU (1) HU220137B (fr)
NZ (1) NZ261250A (fr)
PL (1) PL174772B1 (fr)
PT (1) PT678018E (fr)
RU (2) RU2146128C1 (fr)
SG (1) SG47043A1 (fr)
SK (1) SK74495A3 (fr)
WO (1) WO1994015587A2 (fr)
ZA (1) ZA9477B (fr)

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CA2250981C (fr) * 1996-04-23 2002-07-02 Kinerton Limited Polymeres polylactiques acides
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EP1348444B1 (fr) * 1999-08-18 2006-04-12 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Formulation à effet retardé d'un peptide, complexé avec un polymère
IES990700A2 (en) * 1999-08-18 2001-08-22 Kinerton Ltd Process to make a sustained release formulation
US7109166B1 (en) 1999-08-18 2006-09-19 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Sustained release formulation of a peptide
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KR20220140711A (ko) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법

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Also Published As

Publication number Publication date
FI953314A0 (fi) 1995-07-05
WO1994015587A2 (fr) 1994-07-21
FI953314A (fi) 1995-07-05
EP0678018A1 (fr) 1995-10-25
FI114898B (fi) 2005-01-31
DE69432459D1 (de) 2003-05-15
HU9502029D0 (en) 1995-09-28
AU680650B2 (en) 1997-08-07
ES2196023T3 (es) 2003-12-16
RU2185393C2 (ru) 2002-07-20
PT678018E (pt) 2003-08-29
JPH08505395A (ja) 1996-06-11
NZ261250A (en) 1997-08-22
PL174772B1 (pl) 1998-09-30
ATE236655T1 (de) 2003-04-15
PL309776A1 (en) 1995-11-13
RU2146128C1 (ru) 2000-03-10
HU220137B (hu) 2001-11-28
AU5992194A (en) 1994-08-15
EP0678018A4 (fr) 1998-09-09
DK0678018T3 (da) 2003-04-28
SK74495A3 (en) 1997-01-08
HUT73188A (en) 1996-06-28
CN1115252A (zh) 1996-01-24
WO1994015587A3 (fr) 1994-09-01
CA2150574A1 (fr) 1994-07-21
CZ293425B6 (cs) 2004-04-14
ZA9477B (en) 1994-08-11
CZ293378B6 (cs) 2004-04-14
CN1163260C (zh) 2004-08-25
EP0678018B1 (fr) 2003-04-09
CZ173495A3 (en) 1996-01-17
DE69432459T2 (de) 2003-11-27

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