SG144914A1 - A method for the preparation of enantiomerically pure mirtazapine - Google Patents
A method for the preparation of enantiomerically pure mirtazapineInfo
- Publication number
- SG144914A1 SG144914A1 SG200805127-8A SG2008051278A SG144914A1 SG 144914 A1 SG144914 A1 SG 144914A1 SG 2008051278 A SG2008051278 A SG 2008051278A SG 144914 A1 SG144914 A1 SG 144914A1
- Authority
- SG
- Singapore
- Prior art keywords
- preparation
- enantiomerically pure
- pure mirtazapine
- mirtazapine
- enantiomerically
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03102095 | 2003-07-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG144914A1 true SG144914A1 (en) | 2008-08-28 |
Family
ID=34042934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG200805127-8A SG144914A1 (en) | 2003-07-10 | 2004-07-05 | A method for the preparation of enantiomerically pure mirtazapine |
Country Status (36)
| Country | Link |
|---|---|
| US (2) | US8058436B2 (es) |
| EP (1) | EP1656365B1 (es) |
| JP (1) | JP4668184B2 (es) |
| KR (1) | KR20060056315A (es) |
| CN (1) | CN100558722C (es) |
| AR (1) | AR046494A1 (es) |
| AT (1) | ATE433965T1 (es) |
| AU (1) | AU2004255874B2 (es) |
| BR (1) | BRPI0412447A (es) |
| CA (1) | CA2531165C (es) |
| CO (1) | CO5640123A2 (es) |
| CY (1) | CY1109327T1 (es) |
| DE (1) | DE602004021605D1 (es) |
| DK (1) | DK1656365T3 (es) |
| EC (1) | ECSP066271A (es) |
| ES (1) | ES2327123T3 (es) |
| HK (1) | HK1086841A1 (es) |
| HR (1) | HRP20051019A2 (es) |
| IL (1) | IL172549A0 (es) |
| IS (1) | IS2674B (es) |
| LT (1) | LT5382B (es) |
| LV (1) | LV13441B (es) |
| MX (1) | MXPA06000325A (es) |
| NO (1) | NO20056175L (es) |
| NZ (1) | NZ544360A (es) |
| PE (1) | PE20050323A1 (es) |
| PL (1) | PL1656365T3 (es) |
| PT (1) | PT1656365E (es) |
| RS (1) | RS20050972A (es) |
| RU (1) | RU2352566C2 (es) |
| SG (1) | SG144914A1 (es) |
| SI (1) | SI1656365T1 (es) |
| TW (1) | TWI335915B (es) |
| UA (1) | UA83666C2 (es) |
| WO (1) | WO2005005410A1 (es) |
| ZA (1) | ZA200600019B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1930325A4 (en) * | 2005-09-26 | 2010-02-24 | Sumitomo Chemical Co | METHOD FOR PRODUCING AN OPTICALLY ACTIVE PIPERAZINE COMPOUND |
| JP5080050B2 (ja) * | 2005-09-26 | 2012-11-21 | 住友化学株式会社 | 光学活性なピペラジン化合物の製造方法 |
| TW200808804A (en) * | 2006-05-22 | 2008-02-16 | Organon Nv | Mirtazapine for the treatment of neuropathic pain |
| TW200815370A (en) * | 2006-06-16 | 2008-04-01 | Organon Nv | Stereoselective synthesis of (S)-1-methyl-3-phenylpiperazine |
| EP2119709A4 (en) * | 2007-02-09 | 2011-08-17 | Kaneka Corp | PROCESS FOR PREPARING OPTICALLY ACTIVE 2-ARYLPIPERAZINE DERIVATIVE |
| JP5192707B2 (ja) * | 2007-03-22 | 2013-05-08 | 住友化学株式会社 | ミルタザピンの製造方法 |
| US7994314B2 (en) | 2007-04-11 | 2011-08-09 | N.V. Organon | Method for the preparation of an enantiomerically pure benzazepine |
| MX2009010967A (es) | 2007-04-11 | 2009-12-15 | Organon Nv | Un metodo para la preparacion de mirtazapina. |
| KR101485418B1 (ko) * | 2013-05-29 | 2015-01-26 | 주식회사 메디켐코리아 | 고순도 미르타자핀의 제조방법 |
| DK3261645T3 (da) | 2015-02-27 | 2021-06-07 | Dechra Ltd | Stimulering af appetit, håndtering af vægttab og behandling af anoreksi hos hunde og katte |
| KR102540021B1 (ko) * | 2020-12-02 | 2023-06-07 | (주)유케이케미팜 | 대량 생산에 적합한 미르타자핀의 제조방법 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3959470A (en) * | 1972-11-28 | 1976-05-25 | Mikhail Davidovich Mashkovsky | Psychotropic medicinal preparation |
| NL189199C (nl) * | 1975-04-05 | 1993-02-01 | Akzo Nv | Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten. |
| PT95522B (pt) * | 1989-10-05 | 1997-08-29 | Sankyo Co | Processo para a preparacao de novos compostos tetraciclicos com accao anti-alergica e anti-asmatica e de composicoes farmaceuticas que os contem |
| PT1030667E (pt) | 1997-11-14 | 2005-06-30 | Akzo Nobel Nv | Utilizacao de mirtazapina para o fabrico de um medicamento para o tratamento de apenas do sono |
| JPH11222407A (ja) * | 1997-11-14 | 1999-08-17 | Sankyo Co Ltd | 新規殺菌剤 |
| PL366289A1 (en) * | 1999-04-19 | 2005-01-24 | Teva Pharmaceutical Industries Ltd. | Novel synthesis and crystallization of piperazine ring-containing compounds |
| US20030069417A1 (en) * | 1999-04-19 | 2003-04-10 | Claude Singer | Novel synthesis and crystallization of piperazine ring-containing compounds |
| US6068695A (en) * | 1999-07-13 | 2000-05-30 | Bayer Corporation | Process for the continuous preparation of quinacridones |
| AU6476300A (en) | 1999-09-30 | 2001-05-10 | Sumika Fine Chemicals Co., Ltd. | Process for the preparation of a piperazine derivative |
| WO2001042239A1 (fr) * | 1999-12-13 | 2001-06-14 | Sumika Fine Chemicals Co., Ltd. | Procede de preparation d'un compose pyridinemethanol |
| PL206073B1 (pl) | 2000-02-11 | 2010-06-30 | Organon Nv | Zastosowanie mirtazapiny do wytwarzania leku |
| JP2001342188A (ja) * | 2000-03-27 | 2001-12-11 | Takeda Chem Ind Ltd | 縮合ピラゾール誘導体、その製造法および用途 |
| TW200538100A (en) * | 2004-04-21 | 2005-12-01 | Akzo Nobel Nv | Mirtazapine salts |
-
2004
- 2004-05-07 UA UAA200600274A patent/UA83666C2/ru unknown
- 2004-06-28 TW TW093118845A patent/TWI335915B/zh not_active IP Right Cessation
- 2004-07-05 SG SG200805127-8A patent/SG144914A1/en unknown
- 2004-07-05 SI SI200431183T patent/SI1656365T1/sl unknown
- 2004-07-05 AU AU2004255874A patent/AU2004255874B2/en not_active Expired
- 2004-07-05 CA CA2531165A patent/CA2531165C/en not_active Expired - Fee Related
- 2004-07-05 DK DK04741958T patent/DK1656365T3/da active
- 2004-07-05 US US10/564,193 patent/US8058436B2/en not_active Expired - Fee Related
- 2004-07-05 EP EP04741958A patent/EP1656365B1/en not_active Expired - Lifetime
- 2004-07-05 PL PL04741958T patent/PL1656365T3/pl unknown
- 2004-07-05 PT PT04741958T patent/PT1656365E/pt unknown
- 2004-07-05 JP JP2006518216A patent/JP4668184B2/ja not_active Expired - Lifetime
- 2004-07-05 MX MXPA06000325A patent/MXPA06000325A/es active IP Right Grant
- 2004-07-05 KR KR1020067000511A patent/KR20060056315A/ko active IP Right Grant
- 2004-07-05 CN CNB2004800194891A patent/CN100558722C/zh not_active Expired - Lifetime
- 2004-07-05 NZ NZ544360A patent/NZ544360A/en not_active IP Right Cessation
- 2004-07-05 RU RU2006103992/04A patent/RU2352566C2/ru not_active IP Right Cessation
- 2004-07-05 BR BRPI0412447-2A patent/BRPI0412447A/pt not_active IP Right Cessation
- 2004-07-05 DE DE602004021605T patent/DE602004021605D1/de not_active Expired - Lifetime
- 2004-07-05 ES ES04741958T patent/ES2327123T3/es not_active Expired - Lifetime
- 2004-07-05 RS YUP-2005/0972A patent/RS20050972A/sr unknown
- 2004-07-05 WO PCT/EP2004/051357 patent/WO2005005410A1/en active IP Right Grant
- 2004-07-05 AT AT04741958T patent/ATE433965T1/de active
- 2004-07-07 PE PE2004000653A patent/PE20050323A1/es not_active Application Discontinuation
- 2004-07-08 AR ARP040102412A patent/AR046494A1/es not_active Application Discontinuation
-
2005
- 2005-12-12 LT LT2005107A patent/LT5382B/lt not_active IP Right Cessation
- 2005-12-13 IL IL172549A patent/IL172549A0/en not_active IP Right Cessation
- 2005-12-15 IS IS8184A patent/IS2674B/is unknown
- 2005-12-22 HR HR20051019A patent/HRP20051019A2/xx not_active Application Discontinuation
- 2005-12-23 NO NO20056175A patent/NO20056175L/no not_active Application Discontinuation
-
2006
- 2006-01-03 ZA ZA200600019A patent/ZA200600019B/en unknown
- 2006-01-09 EC EC2006006271A patent/ECSP066271A/es unknown
- 2006-01-10 CO CO06001617A patent/CO5640123A2/es not_active Application Discontinuation
- 2006-02-10 LV LVP-06-21A patent/LV13441B/en unknown
- 2006-08-17 HK HK06109133.3A patent/HK1086841A1/xx not_active IP Right Cessation
-
2008
- 2008-07-02 US US12/667,969 patent/US20100179319A1/en not_active Abandoned
-
2009
- 2009-08-25 CY CY20091100894T patent/CY1109327T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG145694A1 (en) | Novel compounds | |
| TW200617019A (en) | A process for the preparation of 7α-alkylated 19-norsteroids | |
| HK1086841A1 (en) | A method for the preparation of enantiomerically pure mirtazapine | |
| HK1095817A1 (en) | Method for the production of amino crotonyl compounds | |
| GB2432609A (en) | Method of expansion | |
| AU150501S (en) | A toothbrush | |
| GB0304799D0 (en) | Novel method | |
| GB0207724D0 (en) | Patent submission-Ruthenium as non-magnetic sedlayer for electrodeposition | |
| PL1697390T3 (pl) | Sposób wytwarzania organoacylofosforynów | |
| AU2003294647A8 (en) | Method for producing hydrogen | |
| HK1096398A1 (en) | Method for the manufacture of thip thip | |
| SG148154A1 (en) | Benzannelated compounds as ppar activators | |
| EP1632478A4 (en) | PROCESS FOR PRODUCING PURIFIED 2-CYANOACRYLATE | |
| EP1666442A4 (en) | PROCESS FOR PRODUCING CUMENE | |
| HK1133870A1 (en) | Method for producing 4-pentafluoride-sulfanyl-benzoylguanidines | |
| EP1619167A4 (en) | PROCESS FOR PREPARING DISODIUM PARAPERIODATE | |
| IL174980A0 (en) | Process for the preparation of a trifluoromethylthioether | |
| AU2003299623A8 (en) | Method of making mercaptoalkylalkyldialkoxysilanes | |
| GEU20041064U (en) | Method for production of Matsoni | |
| AU2003267820A1 (en) | Methods for the production of hydrogen | |
| AU2003267340A1 (en) | Method for the production of polyetherols | |
| AU2003286309A1 (en) | Method for producing pure disodium pamidronate | |
| GB0320446D0 (en) | Method for producing hydrogen | |
| PL359045A1 (en) | Method for manufacture of amlodipne benzenosulphonate | |
| PL362261A1 (en) | Method for manufacture of tri-halogen-methylo-arylsulphones |