SG11202005060YA - Compositions comprising circular polyribonucleotides and uses thereof - Google Patents
Compositions comprising circular polyribonucleotides and uses thereofInfo
- Publication number
- SG11202005060YA SG11202005060YA SG11202005060YA SG11202005060YA SG11202005060YA SG 11202005060Y A SG11202005060Y A SG 11202005060YA SG 11202005060Y A SG11202005060Y A SG 11202005060YA SG 11202005060Y A SG11202005060Y A SG 11202005060YA SG 11202005060Y A SG11202005060Y A SG 11202005060YA
- Authority
- SG
- Singapore
- Prior art keywords
- compositions
- circular polyribonucleotides
- polyribonucleotides
- circular
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762599547P | 2017-12-15 | 2017-12-15 | |
US201862676688P | 2018-05-25 | 2018-05-25 | |
PCT/US2018/065836 WO2019118919A1 (en) | 2017-12-15 | 2018-12-14 | Compositions comprising circular polyribonucleotides and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202005060YA true SG11202005060YA (en) | 2020-06-29 |
Family
ID=66820668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202005060YA SG11202005060YA (en) | 2017-12-15 | 2018-12-14 | Compositions comprising circular polyribonucleotides and uses thereof |
Country Status (13)
Country | Link |
---|---|
US (8) | US20200306286A1 (de) |
EP (1) | EP3724208A4 (de) |
JP (2) | JP2021508490A (de) |
KR (1) | KR20200127152A (de) |
CN (1) | CN111819185A (de) |
AU (2) | AU2018385757B2 (de) |
BR (1) | BR112020011670A2 (de) |
CA (1) | CA3084824A1 (de) |
IL (1) | IL275205A (de) |
MA (1) | MA51155A (de) |
MX (1) | MX2020006150A (de) |
SG (1) | SG11202005060YA (de) |
WO (1) | WO2019118919A1 (de) |
Families Citing this family (59)
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EP3724208A4 (de) | 2017-12-15 | 2021-09-01 | Flagship Pioneering Innovations VI, LLC | Zusammensetzungen mit zirkulären polyribonukleotiden und verwendungen davon |
BR112020024292A2 (pt) | 2018-06-06 | 2021-03-02 | Massachusetts Institute Of Technology | rna circular para translação em células eucarióticas |
JP2022523794A (ja) | 2019-03-04 | 2022-04-26 | フラッグシップ パイオニアリング イノベーションズ シックス,エルエルシー | 環状ポリリボヌクレオチド及びその医薬組成物 |
CN111718929B (zh) * | 2019-03-20 | 2022-10-18 | 中国科学院上海营养与健康研究所 | 利用环形rna进行蛋白翻译及其应用 |
CN113661242A (zh) | 2019-03-25 | 2021-11-16 | 旗舰创业创新第六有限责任公司 | 包含经修饰的环状多核糖核苷酸的组合物及其用途 |
AU2020280105A1 (en) * | 2019-05-22 | 2022-01-20 | Massachusetts Institute Of Technology | Circular RNA compositions and methods |
US20220257794A1 (en) | 2019-06-14 | 2022-08-18 | Flagship Pioneering Innovations Vi, Llc | Circular rnas for cellular therapy |
WO2020257727A1 (en) | 2019-06-19 | 2020-12-24 | Flagship Pioneering Innovations Vi, Llc | Methods of dosing circular polyribonucleotides |
EP3986469A1 (de) | 2019-06-19 | 2022-04-27 | Flagship Pioneering Innovations VI, LLC | Zusammensetzungen mit kreisförmigen polyribonukleotiden zur proteinmodulation und deren verwendungen |
CN112662659B (zh) * | 2019-10-15 | 2022-08-19 | 武汉核圣生物技术有限公司 | 一种普适性的mRNA体外环化方法 |
CA3160739A1 (en) | 2019-12-04 | 2021-06-10 | Brian Goodman | Circular rna compositions and methods |
WO2021155175A1 (en) | 2020-01-29 | 2021-08-05 | Flagship Pioneering Innovations Vi, Llc | Compositions for translation and methods of use thereof |
EP4096681A1 (de) | 2020-01-29 | 2022-12-07 | Flagship Pioneering Innovations VI, LLC | Verabreichung von zusammensetzungen mit zirkulären polyribonukleotiden |
EP4121453A2 (de) * | 2020-03-20 | 2023-01-25 | Orna Therapeutics, Inc. | Zirkuläre rna-zusammensetzungen und verfahren |
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EP4153152A1 (de) | 2020-05-20 | 2023-03-29 | Flagship Pioneering Innovations VI, LLC | Zusammensetzungen und verfahren zur herstellung von humanen polyklonalen antikörpern |
JP2023526422A (ja) | 2020-05-20 | 2023-06-21 | フラッグシップ パイオニアリング イノベーションズ シックス,エルエルシー | コロナウイルス抗原組成物及びそれらの使用 |
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US11160822B2 (en) | 2021-11-02 |
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WO2019118919A1 (en) | 2019-06-20 |
CN111819185A (zh) | 2020-10-23 |
US20220023331A1 (en) | 2022-01-27 |
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CA3084824A1 (en) | 2019-06-20 |
JP2023126888A (ja) | 2023-09-12 |
US20230201241A1 (en) | 2023-06-29 |
AU2024200298A1 (en) | 2024-02-01 |
US20210161938A1 (en) | 2021-06-03 |
US20190307785A1 (en) | 2019-10-10 |
EP3724208A4 (de) | 2021-09-01 |
JP2021508490A (ja) | 2021-03-11 |
AU2018385757A1 (en) | 2020-06-25 |
MA51155A (fr) | 2020-10-21 |
KR20200127152A (ko) | 2020-11-10 |
US20240122959A1 (en) | 2024-04-18 |
BR112020011670A2 (pt) | 2020-11-17 |
US20230070937A1 (en) | 2023-03-09 |
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