SG11201806445UA - Cell mass, cell structure, and three-dimensional tissue body - Google Patents

Cell mass, cell structure, and three-dimensional tissue body

Info

Publication number
SG11201806445UA
SG11201806445UA SG11201806445UA SG11201806445UA SG11201806445UA SG 11201806445U A SG11201806445U A SG 11201806445UA SG 11201806445U A SG11201806445U A SG 11201806445UA SG 11201806445U A SG11201806445U A SG 11201806445UA SG 11201806445U A SG11201806445U A SG 11201806445UA
Authority
SG
Singapore
Prior art keywords
cell
dimensional tissue
tissue body
temperature
responsive polymer
Prior art date
Application number
SG11201806445UA
Other languages
English (en)
Inventor
Yasuhide Nakayama
Ryosuke Iwai
Yasushi Nemoto
Original Assignee
Nat Cerebral & Cardiovascular Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2016016459A external-priority patent/JP2017131198A/ja
Priority claimed from JP2016026293A external-priority patent/JP6800436B2/ja
Priority claimed from JP2016053082A external-priority patent/JP2017163912A/ja
Priority claimed from JP2016053081A external-priority patent/JP2017163911A/ja
Priority claimed from JP2016124458A external-priority patent/JP2017169552A/ja
Priority claimed from JP2016148977A external-priority patent/JP6780816B2/ja
Priority claimed from JP2016162950A external-priority patent/JP6704197B2/ja
Application filed by Nat Cerebral & Cardiovascular Ct filed Critical Nat Cerebral & Cardiovascular Ct
Priority claimed from PCT/JP2017/003879 external-priority patent/WO2017131241A1/fr
Publication of SG11201806445UA publication Critical patent/SG11201806445UA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3612—Cartilage, synovial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/20—Material Coatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2535/00—Supports or coatings for cell culture characterised by topography

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Sustainable Development (AREA)
  • Urology & Nephrology (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Thermal Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SG11201806445UA 2016-01-29 2017-01-27 Cell mass, cell structure, and three-dimensional tissue body SG11201806445UA (en)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP2016016459A JP2017131198A (ja) 2016-01-29 2016-01-29 軟骨細胞塊及び移植材料の製造方法、軟骨細胞塊及び移植材料並びに複合材
JP2016026293A JP6800436B2 (ja) 2016-02-15 2016-02-15 細胞構造体の製造方法、細胞構造体、細胞培養器
JP2016053082A JP2017163912A (ja) 2016-03-16 2016-03-16 細胞構造体の製造方法
JP2016053081A JP2017163911A (ja) 2016-03-16 2016-03-16 細胞構造体の製造方法
JP2016053086 2016-03-16
JP2016053084 2016-03-16
JP2016124458A JP2017169552A (ja) 2016-03-16 2016-06-23 立体組織体の作製装置、及び立体組織体の作製方法
JP2016148977A JP6780816B2 (ja) 2016-03-16 2016-07-28 上皮系細胞の培養方法、細胞構造体の製造方法、及び上皮系細胞用細胞培養器
JP2016162950A JP6704197B2 (ja) 2016-08-23 2016-08-23 細胞構造体の製造方法
PCT/JP2017/003879 WO2017131241A1 (fr) 2016-01-29 2017-01-27 Amas cellulaire, structure cellulaire et corps tissulaire tridimensionnel

Publications (1)

Publication Number Publication Date
SG11201806445UA true SG11201806445UA (en) 2018-08-30

Family

ID=63286992

Family Applications (3)

Application Number Title Priority Date Filing Date
SG11201806445UA SG11201806445UA (en) 2016-01-29 2017-01-27 Cell mass, cell structure, and three-dimensional tissue body
SG10201913267YA SG10201913267YA (en) 2016-01-29 2017-01-27 Cell mass, cell structure, and three-dimensional tissue body
SG10201913270YA SG10201913270YA (en) 2016-01-29 2017-01-27 Cell mass, cell structure, and three-dimensional tissue body

Family Applications After (2)

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SG10201913267YA SG10201913267YA (en) 2016-01-29 2017-01-27 Cell mass, cell structure, and three-dimensional tissue body
SG10201913270YA SG10201913270YA (en) 2016-01-29 2017-01-27 Cell mass, cell structure, and three-dimensional tissue body

Country Status (5)

Country Link
US (1) US11149252B2 (fr)
EP (1) EP3409763A4 (fr)
KR (1) KR20180103075A (fr)
CN (1) CN108699520A (fr)
SG (3) SG11201806445UA (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110292657A (zh) * 2019-08-12 2019-10-01 郑州大学第一附属医院 一种用于组织修复的生物胶囊及其构建方法
KR102228619B1 (ko) * 2019-11-25 2021-03-17 경희대학교 산학협력단 히알루론산 및 폴리에틸렌글리콜을 포함하여 제조된 세포 시트 및 이의 제조방법
DE102019132214B3 (de) * 2019-11-27 2021-04-29 Cellbricks Gmbh Mit biologischen Zellen besiedeltes 3D-Gerüst aus biokompatiblem Polymer und dessen Herstellung
WO2022115800A2 (fr) * 2020-11-30 2022-06-02 Torres Lugo Madeline Matrices synthétiques pour culture cellulaire, leurs procédés de fabrication et d'utilisation

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JPH05260950A (ja) 1992-03-18 1993-10-12 Sumitomo Bakelite Co Ltd コラーゲンコート細胞培養器具およびその製造方法
JPH0614764A (ja) 1992-06-30 1994-01-25 Sumitomo Bakelite Co Ltd ファイブロネクチンコート細胞培養器具及びその製造方法
JPH08173144A (ja) 1994-12-28 1996-07-09 Sumitomo Bakelite Co Ltd ラミニンコート細胞培養器及びその製造方法
EP2298858A1 (fr) 2000-03-16 2011-03-23 Cellseed Inc. Matériau de lit pour culture cellulaire, procédé de co-culture de cellules et feuilles de cellules co-culturées pouvant être ainsi obtenues
JP3646162B2 (ja) 2001-07-04 2005-05-11 独立行政法人産業技術総合研究所 軟骨組織の再生用移植体
JP3680067B2 (ja) 2003-04-15 2005-08-10 矢永博子 移植用軟骨細胞の製法
DK1857126T3 (en) * 2005-02-28 2019-02-04 Cellseed Inc CULTIVATED CELL LAYER, MANUFACTURING THEREOF AND USING THEREOF.
US20100136645A1 (en) 2007-04-17 2010-06-03 Byoung-Hyun Min Method for preparing a cell-derived extracellular matrix scaffold
JP4822012B2 (ja) * 2007-05-22 2011-11-24 大日本印刷株式会社 紐状の心筋細胞集合体を形成するための細胞培養支持体
JP2009050194A (ja) 2007-08-27 2009-03-12 Sumitomo Bakelite Co Ltd 細胞凝集塊形成培養用容器
EP2330182A4 (fr) 2008-09-08 2012-04-25 Univ Tokyo Sci Educ Found Composite de sphéroïdes, hydrogel contenant des sphéroïdes et leurs procédés de fabrication
US9598668B2 (en) * 2008-10-14 2017-03-21 Cellseed Inc. Temperature-responsive cell culture substrate and method for producing the same
JP2013013368A (ja) 2011-07-04 2013-01-24 Dainippon Printing Co Ltd 治療用細胞フラグメント回収用基材およびそれを用いた治療用細胞フラグメントの製造方法、ならびに、継代用細胞フラグメント回収用基材およびそれを用いた継代用細胞フラグメントの製造方法
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JP6062733B2 (ja) * 2012-04-24 2017-01-18 国立研究開発法人国立循環器病研究センター 細胞培養用組成物及び細胞培養器
JP2014027918A (ja) * 2012-04-24 2014-02-13 National Cerebral & Cardiovascular Center 細胞構造体の製造方法、及び該方法により製造された細胞構造体
JP5746240B2 (ja) 2013-02-26 2015-07-08 国立研究開発法人国立循環器病研究センター 温度応答性ポリマーの製造方法、温度応答性ポリマー、細胞培養器の製造方法、及び細胞培養器
JP2015043892A (ja) 2013-08-28 2015-03-12 独立行政法人国立循環器病研究センター 人工気管、人工気管の生産方法、及び人工気管形成用基材
JP6277684B2 (ja) 2013-11-18 2018-02-14 大日本印刷株式会社 細胞積層体の製造方法
JP6468714B2 (ja) 2014-03-31 2019-02-13 学校法人東京女子医科大学 培養容器及びそれを利用した複数の積層細胞シートの作製方法
EP3315596A4 (fr) 2015-06-26 2019-02-13 National Cerebral and Cardiovascular Center Récipient de culture cellulaire
JP6704197B2 (ja) 2016-08-23 2020-06-03 国立研究開発法人国立循環器病研究センター 細胞構造体の製造方法

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Publication number Publication date
SG10201913270YA (en) 2020-03-30
US11149252B2 (en) 2021-10-19
EP3409763A4 (fr) 2019-10-30
KR20180103075A (ko) 2018-09-18
SG10201913267YA (en) 2020-02-27
EP3409763A1 (fr) 2018-12-05
US20190040359A1 (en) 2019-02-07
CN108699520A (zh) 2018-10-23

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