SG10201913267YA - Cell mass, cell structure, and three-dimensional tissue body - Google Patents

Cell mass, cell structure, and three-dimensional tissue body

Info

Publication number
SG10201913267YA
SG10201913267YA SG10201913267YA SG10201913267YA SG10201913267YA SG 10201913267Y A SG10201913267Y A SG 10201913267YA SG 10201913267Y A SG10201913267Y A SG 10201913267YA SG 10201913267Y A SG10201913267Y A SG 10201913267YA SG 10201913267Y A SG10201913267Y A SG 10201913267YA
Authority
SG
Singapore
Prior art keywords
cell
dimensional tissue
tissue body
cell structure
mass
Prior art date
Application number
SG10201913267YA
Inventor
Yasuhide Nakayama
Ryosuke Iwai
Yasushi Nemoto
Original Assignee
Nat Cerebral & Cardiovascular Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2016016459A external-priority patent/JP2017131198A/en
Priority claimed from JP2016026293A external-priority patent/JP6800436B2/en
Priority claimed from JP2016053081A external-priority patent/JP2017163911A/en
Priority claimed from JP2016053082A external-priority patent/JP2017163912A/en
Priority claimed from JP2016124458A external-priority patent/JP2017169552A/en
Priority claimed from JP2016148977A external-priority patent/JP6780816B2/en
Priority claimed from JP2016162950A external-priority patent/JP6704197B2/en
Application filed by Nat Cerebral & Cardiovascular Ct filed Critical Nat Cerebral & Cardiovascular Ct
Publication of SG10201913267YA publication Critical patent/SG10201913267YA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3612—Cartilage, synovial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/20—Material Coatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2535/00—Supports or coatings for cell culture characterised by topography
SG10201913267YA 2016-01-29 2017-01-27 Cell mass, cell structure, and three-dimensional tissue body SG10201913267YA (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP2016016459A JP2017131198A (en) 2016-01-29 2016-01-29 Method for producing chondrocyte cluster and grafting material, chondrocyte cluster and grafting material, and composite material
JP2016026293A JP6800436B2 (en) 2016-02-15 2016-02-15 Manufacturing method of cell structure, cell structure, cell incubator
JP2016053084 2016-03-16
JP2016053081A JP2017163911A (en) 2016-03-16 2016-03-16 Production method of cell structure body
JP2016053086 2016-03-16
JP2016053082A JP2017163912A (en) 2016-03-16 2016-03-16 Production method of cell structure body
JP2016124458A JP2017169552A (en) 2016-03-16 2016-06-23 Apparatus for manufacturing three-dimensional tissue body and method for manufacturing three-dimensional tissue body
JP2016148977A JP6780816B2 (en) 2016-03-16 2016-07-28 Method for culturing epithelial cells, method for producing cell structures, and cell incubator for epithelial cells
JP2016162950A JP6704197B2 (en) 2016-08-23 2016-08-23 Method for producing cell structure

Publications (1)

Publication Number Publication Date
SG10201913267YA true SG10201913267YA (en) 2020-02-27

Family

ID=63286992

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10201913270YA SG10201913270YA (en) 2016-01-29 2017-01-27 Cell mass, cell structure, and three-dimensional tissue body
SG10201913267YA SG10201913267YA (en) 2016-01-29 2017-01-27 Cell mass, cell structure, and three-dimensional tissue body
SG11201806445UA SG11201806445UA (en) 2016-01-29 2017-01-27 Cell mass, cell structure, and three-dimensional tissue body

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201913270YA SG10201913270YA (en) 2016-01-29 2017-01-27 Cell mass, cell structure, and three-dimensional tissue body

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201806445UA SG11201806445UA (en) 2016-01-29 2017-01-27 Cell mass, cell structure, and three-dimensional tissue body

Country Status (5)

Country Link
US (1) US11149252B2 (en)
EP (1) EP3409763A4 (en)
KR (1) KR20180103075A (en)
CN (1) CN108699520A (en)
SG (3) SG10201913270YA (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110292657A (en) * 2019-08-12 2019-10-01 郑州大学第一附属医院 A kind of biological capsule and its construction method for tissue repair
KR102228619B1 (en) * 2019-11-25 2021-03-17 경희대학교 산학협력단 Cell slap prepared by hyaluronic acid and polyethylene glycol and method for preparing the same
DE102019132214B3 (en) * 2019-11-27 2021-04-29 Cellbricks Gmbh 3D scaffold made of biocompatible polymer and its production, colonized with biological cells
WO2022115800A2 (en) * 2020-11-30 2022-06-02 Torres Lugo Madeline Synthetic matrices for cell culture, methods of making and use thereof

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05260950A (en) 1992-03-18 1993-10-12 Sumitomo Bakelite Co Ltd Collagen-coated cell culture apparatus and its production
JPH0614764A (en) 1992-06-30 1994-01-25 Sumitomo Bakelite Co Ltd Cell culture tool coated with fibronectin and its production
JPH08173144A (en) 1994-12-28 1996-07-09 Sumitomo Bakelite Co Ltd Laminin-coated cell incubator and its production
EP1264877B1 (en) * 2000-03-16 2013-10-02 Cellseed Inc. Cell cultivation-support material, method of cocultivation of cells and cocultivated cell sheet obtained therefrom
JP3646162B2 (en) 2001-07-04 2005-05-11 独立行政法人産業技術総合研究所 Transplant for cartilage tissue regeneration
JP3680067B2 (en) 2003-04-15 2005-08-10 矢永博子 Production of chondrocytes for transplantation
ES2693609T3 (en) 2005-02-28 2018-12-12 Cellseed Inc. Sheet of cultured cells, method for their production and method for their application
US20100136645A1 (en) 2007-04-17 2010-06-03 Byoung-Hyun Min Method for preparing a cell-derived extracellular matrix scaffold
JP4822012B2 (en) * 2007-05-22 2011-11-24 大日本印刷株式会社 Cell culture support for forming string-like cardiomyocyte aggregates
JP2009050194A (en) 2007-08-27 2009-03-12 Sumitomo Bakelite Co Ltd Vessel for cell aggregate-forming culture
EP2330182A4 (en) 2008-09-08 2012-04-25 Univ Tokyo Sci Educ Found Spheroid composite, spheroid-containing hydrogel and processes for production of same
US9598668B2 (en) * 2008-10-14 2017-03-21 Cellseed Inc. Temperature-responsive cell culture substrate and method for producing the same
JP2013013368A (en) 2011-07-04 2013-01-24 Dainippon Printing Co Ltd Matrix for recovering cell fragments for therapeutic use, method for producing cell fragment for therapeutic use using the same, matrix for recovering cell fragment for subculture, and method for producing cell fragment for subculture using the same
EP2781594A4 (en) 2011-11-20 2015-04-08 Univ Tokyo Womens Medical Cell culture substrate, and method for manufacturing same
JP2014027918A (en) * 2012-04-24 2014-02-13 National Cerebral & Cardiovascular Center Production method of cell structure, and cell structure produced by the same
JP6062733B2 (en) * 2012-04-24 2017-01-18 国立研究開発法人国立循環器病研究センター Cell culture composition and cell culture vessel
JP5746240B2 (en) 2013-02-26 2015-07-08 国立研究開発法人国立循環器病研究センター Temperature-responsive polymer manufacturing method, temperature-responsive polymer, cell culture device manufacturing method, and cell culture device
JP2015043892A (en) 2013-08-28 2015-03-12 独立行政法人国立循環器病研究センター Artificial trachea, manufacturing method of artificial trachea, and substrate for forming artificial trachea
JP6277684B2 (en) 2013-11-18 2018-02-14 大日本印刷株式会社 Method for producing cell laminate
JP6468714B2 (en) 2014-03-31 2019-02-13 学校法人東京女子医科大学 Cultivation container and method for producing a plurality of laminated cell sheets using the same
CN107709539A (en) 2015-06-26 2018-02-16 国立研究开发法人国立循环器病研究中心 Cell culture apparatus
JP6704197B2 (en) 2016-08-23 2020-06-03 国立研究開発法人国立循環器病研究センター Method for producing cell structure

Also Published As

Publication number Publication date
EP3409763A1 (en) 2018-12-05
KR20180103075A (en) 2018-09-18
EP3409763A4 (en) 2019-10-30
SG10201913270YA (en) 2020-03-30
US11149252B2 (en) 2021-10-19
US20190040359A1 (en) 2019-02-07
CN108699520A (en) 2018-10-23
SG11201806445UA (en) 2018-08-30

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