MX368780B - Matrices de micro-entornos de cultivos celulares discretos, metodos para producir estas matrices y usos de las mismas. - Google Patents

Matrices de micro-entornos de cultivos celulares discretos, metodos para producir estas matrices y usos de las mismas.

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Publication number
MX368780B
MX368780B MX2015015406A MX2015015406A MX368780B MX 368780 B MX368780 B MX 368780B MX 2015015406 A MX2015015406 A MX 2015015406A MX 2015015406 A MX2015015406 A MX 2015015406A MX 368780 B MX368780 B MX 368780B
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MX
Mexico
Prior art keywords
arrays
making
methods
cell culture
discrete cell
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MX2015015406A
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English (en)
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MX2015015406A (es
Inventor
Lutolf Matthias
Ranga Adrian
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Ecole Polytechnique Fed Lausanne Epfl
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Application filed by Ecole Polytechnique Fed Lausanne Epfl filed Critical Ecole Polytechnique Fed Lausanne Epfl
Publication of MX2015015406A publication Critical patent/MX2015015406A/es
Publication of MX368780B publication Critical patent/MX368780B/es

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Clinical Laboratory Science (AREA)
  • Sustainable Development (AREA)
  • Medicinal Preparation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)

Abstract

La invención pertenece a un método combinatorio para identificar las formulaciones de hidrogel que controlan el fenotipo y destino de los tipos celulares difíciles de cultivar. Un método para producir una matriz, caracterizado porque la matriz que tiene volúmenes discretos de micro-entornos de cultivos celulares, que posee diferentes propiedades que influyen en el comportamiento de células encapsuladas, en particular la proliferación , formación de colonias, diferenciación, migración o combinaciones de las mismas.
MX2015015406A 2013-05-08 2014-05-08 Matrices de micro-entornos de cultivos celulares discretos, metodos para producir estas matrices y usos de las mismas. MX368780B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20130166952 EP2801613A1 (en) 2013-05-08 2013-05-08 Arrays of discrete cell culture microenvironments, methods of making such arrays and uses thereof
PCT/EP2014/059501 WO2014180970A1 (en) 2013-05-08 2014-05-08 Arrays of discrete cell culture microenvironments, methods of making such arrays and uses thereof

Publications (2)

Publication Number Publication Date
MX2015015406A MX2015015406A (es) 2016-03-15
MX368780B true MX368780B (es) 2019-10-16

Family

ID=48325462

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015015406A MX368780B (es) 2013-05-08 2014-05-08 Matrices de micro-entornos de cultivos celulares discretos, metodos para producir estas matrices y usos de las mismas.

Country Status (13)

Country Link
US (2) US20160116453A1 (es)
EP (2) EP2801613A1 (es)
JP (1) JP6648005B2 (es)
KR (1) KR20160005122A (es)
CN (1) CN105358675A (es)
AU (1) AU2014264548B2 (es)
BR (1) BR112015027826A2 (es)
CA (1) CA2911380A1 (es)
IL (1) IL242344B (es)
MX (1) MX368780B (es)
RU (1) RU2718491C2 (es)
SG (2) SG11201509214WA (es)
WO (1) WO2014180970A1 (es)

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* Cited by examiner, † Cited by third party
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WO2015172073A1 (en) * 2014-05-08 2015-11-12 Cornell University Bio-adhesive gels and methods of use
BR112017000813B1 (pt) 2014-07-17 2021-03-16 The Regents Of The University Of California sistemas de gel microporoso, usos de uma pluralidade de partículas de microgel em uma solução aquosa e um agente de recozimento, de camadas de sequestrantes covalentemente estabilizados de partículas de microgel, e de um sequestrante covalentemente estabilizado de partículas de microgel com espaços intersticiais, bem como método para a preparação de partículas de microgel
JP6622007B2 (ja) * 2015-05-29 2019-12-18 オリンパス株式会社 細胞評価方法
WO2017036533A1 (en) * 2015-09-03 2017-03-09 Ecole Polytechnique Federale De Lausanne (Epfl) Three-dimensional hydrogels for culturing adult epithelial stem cells and organoids
US11931480B2 (en) 2016-02-16 2024-03-19 The Regents Of The University Of California Microporous annealed particle gels and methods of use
CN106084003B (zh) * 2016-06-12 2019-06-25 国家纳米科学中心 基于细胞内酶催化聚合的多肽单体分子及其在构建纳米材料中的应用
EP3275997A1 (en) * 2016-07-28 2018-01-31 QGel SA Hydrogel precursor formulation and the use thereof
IT201600099380A1 (it) * 2016-10-04 2018-04-04 Univ Bologna Alma Mater Studiorum Composizioni, dispositivi e metodi per il controllo in vitro del microambiente chimico in colture cellulari
EP3336169A1 (en) * 2016-12-15 2018-06-20 Institut Polytechnique de Grenoble Robotic method for coating a multiwell plate by a polyelectrolyte multilayer film
AU2017394923B2 (en) 2016-12-29 2022-07-14 Tempo Therapeutics, Inc. Methods and systems for treating a site of a medical implant
JPWO2018168955A1 (ja) * 2017-03-15 2020-01-16 メカノジェニック株式会社 細胞のｉｎ ｖｉｖｏでの特性を反映した細胞の反応の評価
US11129790B2 (en) 2017-05-19 2021-09-28 Northeastern University Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates
CN112805306B (zh) * 2018-10-04 2024-05-14 洛桑联邦理工学院(Epfl) 可交联聚合物、水凝胶及其制备方法
CN114269544A (zh) 2019-08-06 2022-04-01 洛桑联邦理工学院 用于载细胞树脂的体积增材制造的方法和设备
EP4069823A1 (en) 2019-12-04 2022-10-12 Precision Cancer Technologies Inc. Method and kit for cell growth
EP4105312A1 (en) 2021-06-17 2022-12-21 Bühler AG Method and system for the identification of optimized treatment conditions
WO2023240207A1 (en) * 2022-06-09 2023-12-14 Cellanome, Inc. Cell sorting and selection using degradable hydrogels

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6372494B1 (en) 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
US20060188940A1 (en) * 2005-02-22 2006-08-24 Michael Cima Combinatorial hydrogel formulation
DE102008060991A1 (de) * 2008-12-08 2010-06-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Subtrate zur Selektion und spezifischen Beeinflussung der Funktion von Zellen
EP2566975A4 (en) * 2010-05-03 2014-04-02 Microstem Inc SCREENING METHODS, COMPOSITIONS IDENTIFIED BY THIS METHOD, TOOLS USEFUL FOR THEIR IDENTIFICATION AND CELLULAR POPULATIONS THUS PRODUCED
CA2802557A1 (en) * 2010-06-22 2011-12-29 Universite De Rouen Improved crosslinked hyaluronan hydrogels for 3d cell culture
EP2756096B1 (en) * 2011-09-12 2017-06-28 Ecole Polytechnique Fédérale de Lausanne (EPFL) Method for preparing topographically structured microarrays

Also Published As

Publication number Publication date
EP2801613A1 (en) 2014-11-12
KR20160005122A (ko) 2016-01-13
EP2994527A1 (en) 2016-03-16
CA2911380A1 (en) 2014-11-13
SG10201709159YA (en) 2017-12-28
CN105358675A (zh) 2016-02-24
WO2014180970A1 (en) 2014-11-13
JP2016517694A (ja) 2016-06-20
US20160116453A1 (en) 2016-04-28
US20180113114A1 (en) 2018-04-26
BR112015027826A2 (pt) 2017-08-29
RU2015152344A (ru) 2017-06-16
RU2718491C2 (ru) 2020-04-08
MX2015015406A (es) 2016-03-15
SG11201509214WA (en) 2015-12-30
AU2014264548A1 (en) 2015-11-19
JP6648005B2 (ja) 2020-02-14
AU2014264548B2 (en) 2020-04-30
US10725022B2 (en) 2020-07-28
IL242344B (en) 2021-04-29

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