SG11201606176YA - Heterocyclic compound - Google Patents
Heterocyclic compoundInfo
- Publication number
- SG11201606176YA SG11201606176YA SG11201606176YA SG11201606176YA SG11201606176YA SG 11201606176Y A SG11201606176Y A SG 11201606176YA SG 11201606176Y A SG11201606176Y A SG 11201606176YA SG 11201606176Y A SG11201606176Y A SG 11201606176YA SG 11201606176Y A SG11201606176Y A SG 11201606176YA
- Authority
- SG
- Singapore
- Prior art keywords
- heterocyclic compound
- heterocyclic
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014025944 | 2014-02-13 | ||
| PCT/JP2015/000640 WO2015122188A1 (en) | 2014-02-13 | 2015-02-12 | Heterocyclic compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201606176YA true SG11201606176YA (en) | 2016-08-30 |
Family
ID=52589730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201606176YA SG11201606176YA (en) | 2014-02-13 | 2015-02-12 | Heterocyclic compound |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US9428470B2 (es) |
| EP (1) | EP3105228B1 (es) |
| JP (1) | JP6458054B2 (es) |
| KR (1) | KR20160113299A (es) |
| CN (1) | CN106170487A (es) |
| AR (1) | AR099399A1 (es) |
| AU (1) | AU2015216439A1 (es) |
| BR (1) | BR112016018548A2 (es) |
| CA (1) | CA2939675A1 (es) |
| CL (1) | CL2016002023A1 (es) |
| CR (1) | CR20160368A (es) |
| EA (1) | EA201691624A1 (es) |
| EC (1) | ECSP16067163A (es) |
| IL (1) | IL247018A0 (es) |
| MA (1) | MA39247B1 (es) |
| MX (1) | MX2016010561A (es) |
| PE (1) | PE20161396A1 (es) |
| PH (1) | PH12016501614A1 (es) |
| SG (1) | SG11201606176YA (es) |
| TW (1) | TW201609677A (es) |
| UY (1) | UY35995A (es) |
| WO (1) | WO2015122188A1 (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9969709B2 (en) | 2013-03-13 | 2018-05-15 | Takeda Pharmaceutical Company Limited | Guanidinobenzoic acid ester compound |
| US9346776B2 (en) | 2014-02-13 | 2016-05-24 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
| WO2015123437A1 (en) | 2014-02-13 | 2015-08-20 | Incyte Corporation | Cyclopropylamines as lsd1 inhibitors |
| US9428470B2 (en) * | 2014-02-13 | 2016-08-30 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| DK3105226T3 (da) | 2014-02-13 | 2019-10-14 | Incyte Corp | Cyclopropylaminer som lsd1-inhibitorer |
| PE20161573A1 (es) | 2014-02-13 | 2017-01-19 | Incyte Corp | Ciclopropilamina como inhibidor de la lsd1 |
| TW201613925A (en) | 2014-07-10 | 2016-04-16 | Incyte Corp | Imidazopyrazines as LSD1 inhibitors |
| WO2016007722A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines and triazolopyrazines as lsd1 inhibitors |
| WO2016007731A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Imidazopyridines and imidazopyrazines as lsd1 inhibitors |
| JP2018080109A (ja) * | 2015-03-16 | 2018-05-24 | 武田薬品工業株式会社 | 治療剤 |
| EP3275874B1 (en) * | 2015-03-27 | 2019-10-30 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
| CN107660205B (zh) | 2015-04-03 | 2021-08-27 | 因赛特公司 | 作为lsd1抑制剂的杂环化合物 |
| CN110402244B (zh) | 2015-08-12 | 2023-02-03 | 因赛特公司 | Lsd1抑制剂的盐 |
| BR112020008676A2 (pt) | 2017-11-02 | 2020-10-27 | Ube Industries, Ltd. | composto, e, composição farmacêutica. |
| JOP20200282A1 (ar) | 2018-05-09 | 2020-11-08 | Lg Chemical Ltd | مركب جديد ينطوي على نشاط مثبط للإنتيروببتيداز |
| TW202024028A (zh) * | 2018-08-27 | 2020-07-01 | 日商思可海雅藥品股份有限公司 | 苯甲酸酯化合物 |
| US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
| WO2021013742A1 (en) | 2019-07-19 | 2021-01-28 | Janssen Pharmaceutica Nv | 5,8-disubstituted-[1,2,4]triazolo[1,5-a]pyridinyl and 5,8-disubstituted-imidazo[1,2-a]pyridine derivatives useful as inhibitors of enteropeptidase |
| JP7327788B2 (ja) * | 2019-08-06 | 2023-08-16 | 学校法人福岡大学 | 糖化産物生成抑制剤及び医薬組成物 |
| EP4054593A1 (en) * | 2019-11-04 | 2022-09-14 | Faraday Pharmaceuticals, Inc. | Use of iodide compounds for the treatment and prevention of chemotherapy-associated cachexia and cardiotoxicity |
| WO2021166899A1 (ja) * | 2020-02-17 | 2021-08-26 | 宇部興産株式会社 | インクレチン様物質と組み合わせて使用するための消化管プロテアーゼ阻害剤を含む薬剤 |
| CN111803652B (zh) * | 2020-08-04 | 2021-09-14 | 南通康是美生物科技有限公司 | 治疗痤疮的化合物在制备治疗痤疮的药物组合物或化妆品组合物中的用途 |
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| JPS5753454A (en) | 1980-09-16 | 1982-03-30 | Torii Yakuhin Kk | Guanidinobenzoate and anticomplementary agent |
| AU527371B2 (en) | 1980-09-16 | 1983-03-03 | Torii & Co., Ltd. | Amidine |
| US5116985A (en) | 1989-12-28 | 1992-05-26 | Snow Brand Milk Products Co., Ltd. | Isoquinoline derivatives and salts thereof |
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| JPH06192085A (ja) | 1992-08-31 | 1994-07-12 | Yuji Inada | ダニアレルギー治療剤 |
| EP0673924A4 (en) | 1992-12-10 | 1996-04-24 | Teikoku Chem Ind Co Ltd | PROPRIONIC ACID DERIVATIVE. |
| JPH0753500A (ja) | 1993-08-16 | 1995-02-28 | Sanwa Kagaku Kenkyusho Co Ltd | グアニジノ安息香酸誘導体及びこれらを有効成分とする蛋白分解酵素阻害剤 |
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| AU2004309271A1 (en) | 2003-12-25 | 2005-07-14 | Takeda Pharmaceutical Company Limited | 3-(4-benzyloxyphenyl)propanoic acid derivatives |
| US7585880B2 (en) | 2003-12-26 | 2009-09-08 | Takeda Pharmaceutical Company Limited | Phenylpropanoic acid derivatives |
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| US20080274945A1 (en) | 2004-11-26 | 2008-11-06 | N.V. Nutricia | Infant Nutrition With Protease Inhibitor |
| US8957070B2 (en) | 2005-04-20 | 2015-02-17 | Takeda Pharmaceutical Company Limited | Glucokinase activator compounds, methods of activating glucokinase and methods of treating diabetes and obesity |
| WO2007013694A1 (ja) | 2005-07-29 | 2007-02-01 | Takeda Pharmaceutical Company Limited | フェノキシアルカン酸化合物 |
| WO2007013689A1 (ja) | 2005-07-29 | 2007-02-01 | Takeda Pharmaceutical Company Limited | シクロプロパンカルボン酸化合物 |
| MX2008001386A (es) | 2005-08-10 | 2008-04-07 | Takeda Pharmaceutical | Agente terapeutico para diabetes. |
| JP2007063225A (ja) | 2005-09-01 | 2007-03-15 | Takeda Chem Ind Ltd | イミダゾピリジン化合物 |
| WO2007087130A2 (en) | 2006-01-12 | 2007-08-02 | Merck & Co., Inc. | Hydroxyalkylarylamide derivatives |
| PT2248812E (pt) | 2006-06-27 | 2014-03-12 | Takeda Pharmaceutical | Compostos cíclicos fundidos como moduladores do receptor gpr40 |
| JP5306818B2 (ja) | 2006-10-18 | 2013-10-02 | 武田薬品工業株式会社 | 縮合複素環化合物 |
| BRPI0717722A2 (pt) | 2006-10-19 | 2013-10-29 | Takeda Pharmaceutical | Composto ou um sal do mesmo, pró-droga, ativador de glicoquinase, agente farmacêutico, métodos para ativar uma glicoquinase em um mamífero e para a profilaxia ou o tratamento de diabetes ou obesidade em um mamífero, e, uso do composto ou uma pró-droga do mesmo |
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| KR20090106660A (ko) | 2007-02-09 | 2009-10-09 | 다케다 야쿠힌 고교 가부시키가이샤 | Ｐｐａｒ-감마의 부분 작용제로서의 축합 고리 화합물 |
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| US20110301155A1 (en) | 2007-06-19 | 2011-12-08 | Tsuneo Yasuma | Indazole compounds for activating glucokinase |
| PL2225261T3 (pl) | 2007-12-03 | 2016-09-30 | Inhibitory boropeptydowe enteropeptydaz i ich zastosowania w leczeniu otyłości, nadwagi i/lub chorób związanych z nieprawidłowym metabolizmem tłuszczów | |
| WO2011071048A1 (ja) | 2009-12-07 | 2011-06-16 | 味の素株式会社 | ヘテロアリールカルボン酸エステル誘導体 |
| ES2618024T3 (es) | 2011-06-07 | 2017-06-20 | Ea Pharma Co., Ltd. | Derivado de éster de ácido carboxílico heterocíclico |
| BR112014006125B1 (pt) | 2011-09-15 | 2022-05-10 | Astellas Pharma Inc | Composto de ácido guanidinobenzóico, composição farmacêutica e uso de tal composto |
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| US9969709B2 (en) | 2013-03-13 | 2018-05-15 | Takeda Pharmaceutical Company Limited | Guanidinobenzoic acid ester compound |
| EA201891009A1 (ru) | 2013-06-21 | 2018-09-28 | Миокардиа, Инк. | Соединения пиримидиндиона |
| SI3311845T1 (sl) | 2013-09-16 | 2020-06-30 | Astrazeneca Ab | Terapevtski polimerni nanodelci in postopki njihove izdelave in uporabe |
| US9428470B2 (en) | 2014-02-13 | 2016-08-30 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| PE20161573A1 (es) | 2014-02-13 | 2017-01-19 | Incyte Corp | Ciclopropilamina como inhibidor de la lsd1 |
| DK3105226T3 (da) | 2014-02-13 | 2019-10-14 | Incyte Corp | Cyclopropylaminer som lsd1-inhibitorer |
| US9346776B2 (en) | 2014-02-13 | 2016-05-24 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
-
2015
- 2015-02-11 US US14/619,464 patent/US9428470B2/en not_active Expired - Fee Related
- 2015-02-12 TW TW104104692A patent/TW201609677A/zh unknown
- 2015-02-12 US US15/117,539 patent/US10023544B2/en not_active Expired - Fee Related
- 2015-02-12 JP JP2016569124A patent/JP6458054B2/ja not_active Expired - Fee Related
- 2015-02-12 BR BR112016018548A patent/BR112016018548A2/pt not_active Application Discontinuation
- 2015-02-12 MA MA39247A patent/MA39247B1/fr unknown
- 2015-02-12 PE PE2016001481A patent/PE20161396A1/es not_active Application Discontinuation
- 2015-02-12 EA EA201691624A patent/EA201691624A1/ru unknown
- 2015-02-12 CA CA2939675A patent/CA2939675A1/en not_active Abandoned
- 2015-02-12 AU AU2015216439A patent/AU2015216439A1/en not_active Abandoned
- 2015-02-12 EP EP15706547.5A patent/EP3105228B1/en active Active
- 2015-02-12 CN CN201580019434.9A patent/CN106170487A/zh active Pending
- 2015-02-12 SG SG11201606176YA patent/SG11201606176YA/en unknown
- 2015-02-12 MX MX2016010561A patent/MX2016010561A/es unknown
- 2015-02-12 CR CR20160368A patent/CR20160368A/es unknown
- 2015-02-12 AR ARP150100410A patent/AR099399A1/es unknown
- 2015-02-12 WO PCT/JP2015/000640 patent/WO2015122188A1/en active Application Filing
- 2015-02-12 KR KR1020167024873A patent/KR20160113299A/ko not_active Application Discontinuation
- 2015-02-12 UY UY0001035995A patent/UY35995A/es not_active Application Discontinuation
-
2016
- 2016-07-31 IL IL247018A patent/IL247018A0/en unknown
- 2016-08-10 CL CL2016002023A patent/CL2016002023A1/es unknown
- 2016-08-11 EC ECIEPI201667163A patent/ECSP16067163A/es unknown
- 2016-08-12 PH PH12016501614A patent/PH12016501614A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112016018548A2 (pt) | 2019-01-15 |
| EP3105228B1 (en) | 2018-09-26 |
| US20160347724A1 (en) | 2016-12-01 |
| WO2015122188A1 (en) | 2015-08-20 |
| TW201609677A (zh) | 2016-03-16 |
| CR20160368A (es) | 2016-12-01 |
| CN106170487A (zh) | 2016-11-30 |
| AR099399A1 (es) | 2016-07-20 |
| CL2016002023A1 (es) | 2017-03-24 |
| PH12016501614A1 (en) | 2017-02-06 |
| ECSP16067163A (es) | 2017-10-31 |
| MA39247B1 (fr) | 2018-04-30 |
| MX2016010561A (es) | 2016-11-16 |
| US9428470B2 (en) | 2016-08-30 |
| JP6458054B2 (ja) | 2019-01-23 |
| US20150225354A1 (en) | 2015-08-13 |
| IL247018A0 (en) | 2016-09-29 |
| UY35995A (es) | 2015-08-31 |
| AU2015216439A1 (en) | 2016-08-11 |
| CA2939675A1 (en) | 2015-08-20 |
| MA39247A1 (fr) | 2017-11-30 |
| EA201691624A1 (ru) | 2017-05-31 |
| JP2017505823A (ja) | 2017-02-23 |
| KR20160113299A (ko) | 2016-09-28 |
| PE20161396A1 (es) | 2017-01-10 |
| US10023544B2 (en) | 2018-07-17 |
| EP3105228A1 (en) | 2016-12-21 |
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