CL2016002023A1 - “compuestos derivados de benzoato-4-(amidoamino)- sustituido con un grupo oxazol dicarboxilico, inhibidores de enteropeptidasa; composición farmacéutica que los comprende; y su uso en el tratamiento de obesidad y diabetes mellitus”. pct - Google Patents

“compuestos derivados de benzoato-4-(amidoamino)- sustituido con un grupo oxazol dicarboxilico, inhibidores de enteropeptidasa; composición farmacéutica que los comprende; y su uso en el tratamiento de obesidad y diabetes mellitus”. pct

Info

Publication number
CL2016002023A1
CL2016002023A1 CL2016002023A CL2016002023A CL2016002023A1 CL 2016002023 A1 CL2016002023 A1 CL 2016002023A1 CL 2016002023 A CL2016002023 A CL 2016002023A CL 2016002023 A CL2016002023 A CL 2016002023A CL 2016002023 A1 CL2016002023 A1 CL 2016002023A1
Authority
CL
Chile
Prior art keywords
obesity
amidoamino
pharmaceutical composition
benzoate
pct
Prior art date
Application number
CL2016002023A
Other languages
English (en)
Inventor
Zenichi Ikeda
Minoru Sasaki
Keiko Kakegawa
Fumiaki Kikuchi
Yoichi Nishikawa
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of CL2016002023A1 publication Critical patent/CL2016002023A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Abstract

LA SOLICITUD SE REFIERE A COMPUESTOS DERIVADOS DE BENZOATO-4-(AMIDOAMINO)- SUSTITUIDO CON UN GRUPO OXAZOL DICARBOXILICO, INHIBIDORES DE ENTEROPEPTIDASA, A UNA COMPOSICIÓN FARMACÉUTICA QUE LOS COMPRENDE Y A SU USO EN EL TRATAMIENTO DE OBESIDAD Y DIABETES MELLITUS.
CL2016002023A 2014-02-13 2016-08-10 “compuestos derivados de benzoato-4-(amidoamino)- sustituido con un grupo oxazol dicarboxilico, inhibidores de enteropeptidasa; composición farmacéutica que los comprende; y su uso en el tratamiento de obesidad y diabetes mellitus”. pct CL2016002023A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2014025944 2014-02-13

Publications (1)

Publication Number Publication Date
CL2016002023A1 true CL2016002023A1 (es) 2017-03-24

Family

ID=52589730

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2016002023A CL2016002023A1 (es) 2014-02-13 2016-08-10 “compuestos derivados de benzoato-4-(amidoamino)- sustituido con un grupo oxazol dicarboxilico, inhibidores de enteropeptidasa; composición farmacéutica que los comprende; y su uso en el tratamiento de obesidad y diabetes mellitus”. pct

Country Status (22)

Country Link
US (2) US9428470B2 (es)
EP (1) EP3105228B1 (es)
JP (1) JP6458054B2 (es)
KR (1) KR20160113299A (es)
CN (1) CN106170487A (es)
AR (1) AR099399A1 (es)
AU (1) AU2015216439A1 (es)
BR (1) BR112016018548A2 (es)
CA (1) CA2939675A1 (es)
CL (1) CL2016002023A1 (es)
CR (1) CR20160368A (es)
EA (1) EA201691624A1 (es)
EC (1) ECSP16067163A (es)
IL (1) IL247018A0 (es)
MA (1) MA39247B1 (es)
MX (1) MX2016010561A (es)
PE (1) PE20161396A1 (es)
PH (1) PH12016501614A1 (es)
SG (1) SG11201606176YA (es)
TW (1) TW201609677A (es)
UY (1) UY35995A (es)
WO (1) WO2015122188A1 (es)

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JP7327788B2 (ja) 2019-08-06 2023-08-16 学校法人福岡大学 糖化産物生成抑制剤及び医薬組成物
AU2020417997A1 (en) * 2019-11-04 2022-06-16 Faraday Pharmaceuticals, Inc. Use of iodide compounds for the treatment and prevention of chemotherapy-associated cachexia and cardiotoxicity
WO2021166899A1 (ja) * 2020-02-17 2021-08-26 宇部興産株式会社 インクレチン様物質と組み合わせて使用するための消化管プロテアーゼ阻害剤を含む薬剤
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Also Published As

Publication number Publication date
BR112016018548A2 (pt) 2019-01-15
US9428470B2 (en) 2016-08-30
EP3105228A1 (en) 2016-12-21
ECSP16067163A (es) 2017-10-31
JP6458054B2 (ja) 2019-01-23
KR20160113299A (ko) 2016-09-28
MX2016010561A (es) 2016-11-16
EA201691624A1 (ru) 2017-05-31
UY35995A (es) 2015-08-31
JP2017505823A (ja) 2017-02-23
AR099399A1 (es) 2016-07-20
MA39247A1 (fr) 2017-11-30
TW201609677A (zh) 2016-03-16
SG11201606176YA (en) 2016-08-30
PH12016501614A1 (en) 2017-02-06
WO2015122188A1 (en) 2015-08-20
AU2015216439A1 (en) 2016-08-11
MA39247B1 (fr) 2018-04-30
US20150225354A1 (en) 2015-08-13
IL247018A0 (en) 2016-09-29
US10023544B2 (en) 2018-07-17
CR20160368A (es) 2016-12-01
CN106170487A (zh) 2016-11-30
EP3105228B1 (en) 2018-09-26
US20160347724A1 (en) 2016-12-01
PE20161396A1 (es) 2017-01-10
CA2939675A1 (en) 2015-08-20

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