SG11201600221YA - Elucidation of ion exchange chromatography input optimization - Google Patents

Elucidation of ion exchange chromatography input optimization

Info

Publication number
SG11201600221YA
SG11201600221YA SG11201600221YA SG11201600221YA SG11201600221YA SG 11201600221Y A SG11201600221Y A SG 11201600221YA SG 11201600221Y A SG11201600221Y A SG 11201600221YA SG 11201600221Y A SG11201600221Y A SG 11201600221YA SG 11201600221Y A SG11201600221Y A SG 11201600221YA
Authority
SG
Singapore
Prior art keywords
elucidation
ion exchange
exchange chromatography
input optimization
chromatography input
Prior art date
Application number
SG11201600221YA
Other languages
English (en)
Inventor
Daniel Mcdonald
Thomas Patapoff
Yajun Wang
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of SG11201600221YA publication Critical patent/SG11201600221YA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/86Signal analysis
    • G01N30/8658Optimising operation parameters
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361Ion-exchange
    • B01D15/362Cation-exchange
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361Ion-exchange
    • B01D15/363Anion-exchange
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3847Multimodal interactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/165Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N30/34Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Confectionery (AREA)
SG11201600221YA 2013-07-12 2014-07-11 Elucidation of ion exchange chromatography input optimization SG11201600221YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361845890P 2013-07-12 2013-07-12
PCT/US2014/046338 WO2015006686A1 (en) 2013-07-12 2014-07-11 Elucidation of ion exchange chromatography input optimization

Publications (1)

Publication Number Publication Date
SG11201600221YA true SG11201600221YA (en) 2016-02-26

Family

ID=51257626

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201600221YA SG11201600221YA (en) 2013-07-12 2014-07-11 Elucidation of ion exchange chromatography input optimization

Country Status (18)

Country Link
US (2) US10274466B2 (cg-RX-API-DMAC7.html)
EP (2) EP3019516B1 (cg-RX-API-DMAC7.html)
JP (2) JP6462681B2 (cg-RX-API-DMAC7.html)
KR (1) KR102251127B1 (cg-RX-API-DMAC7.html)
CN (1) CN105377873B (cg-RX-API-DMAC7.html)
AU (1) AU2014287044B2 (cg-RX-API-DMAC7.html)
BR (1) BR112016000231A8 (cg-RX-API-DMAC7.html)
CA (1) CA2918052A1 (cg-RX-API-DMAC7.html)
ES (1) ES2705700T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20190071T1 (cg-RX-API-DMAC7.html)
IL (1) IL243305B (cg-RX-API-DMAC7.html)
MX (1) MX368107B (cg-RX-API-DMAC7.html)
PL (1) PL3019516T3 (cg-RX-API-DMAC7.html)
RU (1) RU2016104542A (cg-RX-API-DMAC7.html)
SG (1) SG11201600221YA (cg-RX-API-DMAC7.html)
SI (1) SI3019516T1 (cg-RX-API-DMAC7.html)
TR (1) TR201818966T4 (cg-RX-API-DMAC7.html)
WO (1) WO2015006686A1 (cg-RX-API-DMAC7.html)

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WO2016075207A1 (en) * 2014-11-12 2016-05-19 Ge Healthcare Bio-Sciences Ab Method and system for determining the influence of experimental parameters on a liquid chromatography protocol
GB2539420B (en) * 2015-06-16 2021-01-13 Cytiva Sweden Ab Determination of chromatography conditions
US11407838B2 (en) * 2018-04-02 2022-08-09 Amgen Inc. Erenumab compositions and uses thereof
WO2020010304A2 (en) * 2018-07-05 2020-01-09 Ovation Diagnostics Llc BCl-2 Antibodies and Immunoassay for Diagnosis of Cancer
KR20200080748A (ko) * 2018-12-27 2020-07-07 주식회사 폴루스 음이온 교환 크로마토그래피를 이용한 인슐린 전구체의 정제방법
WO2024261724A1 (en) * 2023-06-23 2024-12-26 Lupin Limited Ion-exchange chromatography for separation and analysis of charge variants

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Also Published As

Publication number Publication date
MX368107B (es) 2019-09-18
US10274466B2 (en) 2019-04-30
HRP20190071T1 (hr) 2019-02-22
KR102251127B1 (ko) 2021-05-11
IL243305B (en) 2019-09-26
EP3019516B1 (en) 2018-11-14
CA2918052A1 (en) 2015-01-15
ES2705700T3 (es) 2019-03-26
HK1222183A1 (zh) 2017-06-23
TR201818966T4 (tr) 2019-01-21
JP6462681B2 (ja) 2019-01-30
CN105377873A (zh) 2016-03-02
MX2016000181A (es) 2016-03-09
SI3019516T1 (sl) 2019-02-28
IL243305A0 (en) 2016-03-31
AU2014287044B2 (en) 2020-02-06
BR112016000231A8 (pt) 2019-12-31
PL3019516T3 (pl) 2019-04-30
RU2016104542A (ru) 2017-08-17
CN105377873B (zh) 2021-03-30
WO2015006686A8 (en) 2018-10-04
US10921297B2 (en) 2021-02-16
AU2014287044A1 (en) 2016-02-11
JP2019090818A (ja) 2019-06-13
US20160161455A1 (en) 2016-06-09
US20190310234A1 (en) 2019-10-10
WO2015006686A1 (en) 2015-01-15
EP3536699A1 (en) 2019-09-11
JP2016529489A (ja) 2016-09-23
EP3019516A1 (en) 2016-05-18
KR20160030251A (ko) 2016-03-16

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