HRP20190071T1 - Elucidacija optimizacije unosa kromatografijom ionske izmjene - Google Patents

Elucidacija optimizacije unosa kromatografijom ionske izmjene

Info

Publication number
HRP20190071T1
HRP20190071T1 HRP20190071TT HRP20190071T HRP20190071T1 HR P20190071 T1 HRP20190071 T1 HR P20190071T1 HR P20190071T T HRP20190071T T HR P20190071TT HR P20190071 T HRP20190071 T HR P20190071T HR P20190071 T1 HRP20190071 T1 HR P20190071T1
Authority
HR
Croatia
Prior art keywords
elucidation
ion change
input optimization
change chromatography
chromatography
Prior art date
Application number
HRP20190071TT
Other languages
English (en)
Croatian (hr)
Inventor
Daniel Mcdonald
Thomas PATAPOFF
Yajun Wang
Original Assignee
F. Hoffmann - La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann - La Roche Ag filed Critical F. Hoffmann - La Roche Ag
Publication of HRP20190071T1 publication Critical patent/HRP20190071T1/hr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8658—Optimising operation parameters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3847—Multimodal interactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Confectionery (AREA)
HRP20190071TT 2013-07-12 2014-07-11 Elucidacija optimizacije unosa kromatografijom ionske izmjene HRP20190071T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361845890P 2013-07-12 2013-07-12
EP14745049.8A EP3019516B1 (en) 2013-07-12 2014-07-11 Elucidation of ion exchange chromatography input optimization
PCT/US2014/046338 WO2015006686A1 (en) 2013-07-12 2014-07-11 Elucidation of ion exchange chromatography input optimization

Publications (1)

Publication Number Publication Date
HRP20190071T1 true HRP20190071T1 (hr) 2019-02-22

Family

ID=51257626

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20190071TT HRP20190071T1 (hr) 2013-07-12 2014-07-11 Elucidacija optimizacije unosa kromatografijom ionske izmjene

Country Status (18)

Country Link
US (2) US10274466B2 (cg-RX-API-DMAC7.html)
EP (2) EP3019516B1 (cg-RX-API-DMAC7.html)
JP (2) JP6462681B2 (cg-RX-API-DMAC7.html)
KR (1) KR102251127B1 (cg-RX-API-DMAC7.html)
CN (1) CN105377873B (cg-RX-API-DMAC7.html)
AU (1) AU2014287044B2 (cg-RX-API-DMAC7.html)
BR (1) BR112016000231A8 (cg-RX-API-DMAC7.html)
CA (1) CA2918052A1 (cg-RX-API-DMAC7.html)
ES (1) ES2705700T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20190071T1 (cg-RX-API-DMAC7.html)
IL (1) IL243305B (cg-RX-API-DMAC7.html)
MX (1) MX368107B (cg-RX-API-DMAC7.html)
PL (1) PL3019516T3 (cg-RX-API-DMAC7.html)
RU (1) RU2016104542A (cg-RX-API-DMAC7.html)
SG (1) SG11201600221YA (cg-RX-API-DMAC7.html)
SI (1) SI3019516T1 (cg-RX-API-DMAC7.html)
TR (1) TR201818966T4 (cg-RX-API-DMAC7.html)
WO (1) WO2015006686A1 (cg-RX-API-DMAC7.html)

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WO2016075207A1 (en) * 2014-11-12 2016-05-19 Ge Healthcare Bio-Sciences Ab Method and system for determining the influence of experimental parameters on a liquid chromatography protocol
GB2539420B (en) * 2015-06-16 2021-01-13 Cytiva Sweden Ab Determination of chromatography conditions
US11407838B2 (en) * 2018-04-02 2022-08-09 Amgen Inc. Erenumab compositions and uses thereof
WO2020010304A2 (en) * 2018-07-05 2020-01-09 Ovation Diagnostics Llc BCl-2 Antibodies and Immunoassay for Diagnosis of Cancer
KR20200080748A (ko) * 2018-12-27 2020-07-07 주식회사 폴루스 음이온 교환 크로마토그래피를 이용한 인슐린 전구체의 정제방법
WO2024261724A1 (en) * 2023-06-23 2024-12-26 Lupin Limited Ion-exchange chromatography for separation and analysis of charge variants

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Also Published As

Publication number Publication date
MX368107B (es) 2019-09-18
US10274466B2 (en) 2019-04-30
KR102251127B1 (ko) 2021-05-11
IL243305B (en) 2019-09-26
EP3019516B1 (en) 2018-11-14
CA2918052A1 (en) 2015-01-15
ES2705700T3 (es) 2019-03-26
HK1222183A1 (zh) 2017-06-23
TR201818966T4 (tr) 2019-01-21
JP6462681B2 (ja) 2019-01-30
CN105377873A (zh) 2016-03-02
MX2016000181A (es) 2016-03-09
SI3019516T1 (sl) 2019-02-28
IL243305A0 (en) 2016-03-31
SG11201600221YA (en) 2016-02-26
AU2014287044B2 (en) 2020-02-06
BR112016000231A8 (pt) 2019-12-31
PL3019516T3 (pl) 2019-04-30
RU2016104542A (ru) 2017-08-17
CN105377873B (zh) 2021-03-30
WO2015006686A8 (en) 2018-10-04
US10921297B2 (en) 2021-02-16
AU2014287044A1 (en) 2016-02-11
JP2019090818A (ja) 2019-06-13
US20160161455A1 (en) 2016-06-09
US20190310234A1 (en) 2019-10-10
WO2015006686A1 (en) 2015-01-15
EP3536699A1 (en) 2019-09-11
JP2016529489A (ja) 2016-09-23
EP3019516A1 (en) 2016-05-18
KR20160030251A (ko) 2016-03-16

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