SG11201506488WA - Monocyclic pyridine derivative - Google Patents
Monocyclic pyridine derivativeInfo
- Publication number
- SG11201506488WA SG11201506488WA SG11201506488WA SG11201506488WA SG11201506488WA SG 11201506488W A SG11201506488W A SG 11201506488WA SG 11201506488W A SG11201506488W A SG 11201506488WA SG 11201506488W A SG11201506488W A SG 11201506488WA SG 11201506488W A SG11201506488W A SG 11201506488WA
- Authority
- SG
- Singapore
- Prior art keywords
- pyridine derivative
- monocyclic pyridine
- monocyclic
- derivative
- pyridine
- Prior art date
Links
- -1 Monocyclic pyridine derivative Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361766922P | 2013-02-20 | 2013-02-20 | |
| PCT/JP2014/053819 WO2014129477A1 (ja) | 2013-02-20 | 2014-02-18 | 単環ピリジン誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201506488WA true SG11201506488WA (en) | 2015-09-29 |
Family
ID=51351646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201506488WA SG11201506488WA (en) | 2013-02-20 | 2014-02-18 | Monocyclic pyridine derivative |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US8933099B2 (es) |
| EP (1) | EP2960238B1 (es) |
| JP (2) | JP5600229B1 (es) |
| KR (1) | KR102050128B1 (es) |
| CN (1) | CN105073730B (es) |
| AR (1) | AR094812A1 (es) |
| AU (1) | AU2014219811B2 (es) |
| BR (1) | BR112015019790B1 (es) |
| CA (1) | CA2901585C (es) |
| CL (1) | CL2015002311A1 (es) |
| CY (1) | CY1119220T1 (es) |
| DK (1) | DK2960238T3 (es) |
| ES (1) | ES2628495T3 (es) |
| HK (1) | HK1215949A1 (es) |
| HR (1) | HRP20170873T1 (es) |
| HU (1) | HUE032931T2 (es) |
| IL (1) | IL240623B (es) |
| JO (1) | JO3261B1 (es) |
| LT (1) | LT2960238T (es) |
| ME (1) | ME02755B (es) |
| MX (1) | MX361870B (es) |
| MY (1) | MY178760A (es) |
| NZ (1) | NZ711101A (es) |
| PE (1) | PE20151509A1 (es) |
| PH (1) | PH12015501813A1 (es) |
| PL (1) | PL2960238T3 (es) |
| PT (1) | PT2960238T (es) |
| RS (1) | RS56064B1 (es) |
| RU (1) | RU2645352C2 (es) |
| SG (1) | SG11201506488WA (es) |
| SI (1) | SI2960238T1 (es) |
| TW (4) | TWI672296B (es) |
| UA (1) | UA116794C2 (es) |
| WO (1) | WO2014129477A1 (es) |
| ZA (1) | ZA201505941B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102344105B1 (ko) * | 2014-08-18 | 2021-12-29 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 모노시클릭 피리딘 유도체의 염 및 이의 결정 |
| MX2017009892A (es) * | 2015-03-25 | 2017-11-15 | Nat Cancer Ct | Agente terapeutico contra el colangiocarcinoma. |
| US20180303817A1 (en) * | 2015-12-17 | 2018-10-25 | Eisai R&D Management Co., Ltd. | Therapeutic agent for breast cancer |
| CN107098884A (zh) * | 2016-02-19 | 2017-08-29 | 中国科学院上海药物研究所 | 一类取代的氨基吡啶类化合物及其制备和用途 |
| RU2020108284A (ru) * | 2017-10-12 | 2021-11-12 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Фармацевтическая композиция, содержащая селективный ингибитор тирозинкиназы fgfr |
| MX2020008610A (es) | 2018-03-28 | 2020-09-21 | Eisai R&D Man Co Ltd | Agente terapeutico para carcinoma hepatocelular. |
| CA3129665A1 (en) | 2019-03-21 | 2020-09-24 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| KR20220098759A (ko) | 2019-11-08 | 2022-07-12 | 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) | 키나제 억제제에 대해 내성을 획득한 암의 치료 방법 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| CA3180128A1 (en) * | 2020-04-17 | 2021-10-21 | Eisai R&D Management Co., Ltd. | Breast cancer therapeutic agent |
| TW202220652A (zh) | 2020-07-31 | 2022-06-01 | 日商衛材R&D企管股份有限公司 | 乳癌治療劑 |
| EP4209216A1 (en) | 2020-10-28 | 2023-07-12 | Eisai R&D Management Co., Ltd | Pharmaceutical composition for treating tumors |
| EP4361139A1 (en) * | 2021-08-31 | 2024-05-01 | Eisai R&D Management Co., Ltd. | Production method for synthetic intermediate of monocyclic pyridine derivative |
| EP4361143A1 (en) | 2021-08-31 | 2024-05-01 | Eisai R&D Management Co., Ltd. | Method for producing monocyclic pyridine derivative |
| WO2023174400A1 (zh) * | 2022-03-18 | 2023-09-21 | 上海润石医药科技有限公司 | 一种取代的氨基六元氮杂环类化合物的盐及其晶型、制备方法和应用 |
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| WO2002081420A1 (fr) | 2001-04-03 | 2002-10-17 | Eisai Co., Ltd. | Derive de cyclooctanone et derive de cyclodecanone et utilisation de ces derives |
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| NZ538617A (en) * | 2002-08-30 | 2005-12-23 | Eisai Co Ltd | Azaarene derivatives |
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2014
- 2014-02-17 AR ARP140100495A patent/AR094812A1/es active IP Right Grant
- 2014-02-18 KR KR1020157022252A patent/KR102050128B1/ko active IP Right Grant
- 2014-02-18 NZ NZ711101A patent/NZ711101A/en unknown
- 2014-02-18 SI SI201430247A patent/SI2960238T1/sl unknown
- 2014-02-18 PT PT147542948T patent/PT2960238T/pt unknown
- 2014-02-18 EP EP14754294.8A patent/EP2960238B1/en active Active
- 2014-02-18 RS RS20170596A patent/RS56064B1/sr unknown
- 2014-02-18 JP JP2014526292A patent/JP5600229B1/ja active Active
- 2014-02-18 MX MX2015010698A patent/MX361870B/es active IP Right Grant
- 2014-02-18 ES ES14754294.8T patent/ES2628495T3/es active Active
- 2014-02-18 PL PL14754294T patent/PL2960238T3/pl unknown
- 2014-02-18 AU AU2014219811A patent/AU2014219811B2/en active Active
- 2014-02-18 LT LTEP14754294.8T patent/LT2960238T/lt unknown
- 2014-02-18 BR BR112015019790-6A patent/BR112015019790B1/pt active IP Right Grant
- 2014-02-18 RU RU2015134558A patent/RU2645352C2/ru active
- 2014-02-18 CA CA2901585A patent/CA2901585C/en active Active
- 2014-02-18 DK DK14754294.8T patent/DK2960238T3/en active
- 2014-02-18 MY MYPI2015702696A patent/MY178760A/en unknown
- 2014-02-18 TW TW107134522A patent/TWI672296B/zh active
- 2014-02-18 CN CN201480009370.XA patent/CN105073730B/zh active Active
- 2014-02-18 HU HUE14754294A patent/HUE032931T2/en unknown
- 2014-02-18 JO JOP/2014/0039A patent/JO3261B1/ar active
- 2014-02-18 ME MEP-2017-130A patent/ME02755B/me unknown
- 2014-02-18 TW TW107134526A patent/TWI672139B/zh active
- 2014-02-18 TW TW107134529A patent/TWI672140B/zh active
- 2014-02-18 PE PE2015001748A patent/PE20151509A1/es active IP Right Grant
- 2014-02-18 UA UAA201508149A patent/UA116794C2/uk unknown
- 2014-02-18 WO PCT/JP2014/053819 patent/WO2014129477A1/ja active Application Filing
- 2014-02-18 SG SG11201506488WA patent/SG11201506488WA/en unknown
- 2014-02-18 TW TW103105419A patent/TWI641602B/zh active
- 2014-02-19 US US14/183,864 patent/US8933099B2/en active Active
- 2014-08-14 JP JP2014165311A patent/JP2014237707A/ja active Pending
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2015
- 2015-08-17 IL IL240623A patent/IL240623B/en active IP Right Grant
- 2015-08-18 CL CL2015002311A patent/CL2015002311A1/es unknown
- 2015-08-18 PH PH12015501813A patent/PH12015501813A1/en unknown
- 2015-08-18 ZA ZA2015/05941A patent/ZA201505941B/en unknown
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2016
- 2016-04-06 HK HK16103911.2A patent/HK1215949A1/zh unknown
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2017
- 2017-06-07 HR HRP20170873TT patent/HRP20170873T1/hr unknown
- 2017-06-15 CY CY20171100631T patent/CY1119220T1/el unknown
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