SE9704400D0 - Porous inorganic particles as carriers for drug substances - Google Patents

Porous inorganic particles as carriers for drug substances

Info

Publication number
SE9704400D0
SE9704400D0 SE9704400A SE9704400A SE9704400D0 SE 9704400 D0 SE9704400 D0 SE 9704400D0 SE 9704400 A SE9704400 A SE 9704400A SE 9704400 A SE9704400 A SE 9704400A SE 9704400 D0 SE9704400 D0 SE 9704400D0
Authority
SE
Sweden
Prior art keywords
inorganic particles
porous inorganic
oily
greasy
sticky
Prior art date
Application number
SE9704400A
Other languages
English (en)
Swedish (sv)
Inventor
Christer Karlsson
Per Johan Lundberg
Adam Rosinski
Malin Soederbom
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9704400A priority Critical patent/SE9704400D0/xx
Publication of SE9704400D0 publication Critical patent/SE9704400D0/xx
Priority to TW087117781A priority patent/TW524694B/zh
Priority to ARP980105798A priority patent/AR016683A1/es
Priority to ZA9810463A priority patent/ZA9810463B/xx
Priority to US09/214,318 priority patent/US6558703B1/en
Priority to AU13563/99A priority patent/AU752044B2/en
Priority to SK660-2000A priority patent/SK6602000A3/sk
Priority to PT98957268T priority patent/PT1032370E/pt
Priority to SI9830597T priority patent/SI1032370T1/xx
Priority to PL98340927A priority patent/PL340927A1/xx
Priority to CA002311780A priority patent/CA2311780A1/en
Priority to DK98957268T priority patent/DK1032370T3/da
Priority to RU2000113731/15A priority patent/RU2219907C2/ru
Priority to EP98957268A priority patent/EP1032370B1/en
Priority to NZ504353A priority patent/NZ504353A/en
Priority to HU0100303A priority patent/HUP0100303A3/hu
Priority to IDW20000937A priority patent/ID24700A/id
Priority to BR9814751-0A priority patent/BR9814751A/pt
Priority to PCT/SE1998/002089 priority patent/WO1999027912A1/en
Priority to KR1020007005802A priority patent/KR20010032557A/ko
Priority to AT98957268T priority patent/ATE256453T1/de
Priority to IL13614698A priority patent/IL136146A0/xx
Priority to JP2000522898A priority patent/JP2001524513A/ja
Priority to ES98957268T priority patent/ES2210840T3/es
Priority to DE69820674T priority patent/DE69820674T2/de
Priority to CN98811634A priority patent/CN1280492A/zh
Priority to NO20002719A priority patent/NO20002719L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/005—Enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE9704400A 1997-11-28 1997-11-28 Porous inorganic particles as carriers for drug substances SE9704400D0 (sv)

Priority Applications (27)

Application Number Priority Date Filing Date Title
SE9704400A SE9704400D0 (sv) 1997-11-28 1997-11-28 Porous inorganic particles as carriers for drug substances
TW087117781A TW524694B (en) 1997-11-28 1998-10-27 Porous inorganic particles as carriers for drug substances
ARP980105798A AR016683A1 (es) 1997-11-28 1998-11-16 Composicion de suministro de droga solida, anhidra, proceso y uso de una pluralidad de particulas inorganicas porosas compuestas de hidroxipatita ceramicapara su preparacion.
ZA9810463A ZA9810463B (en) 1997-11-28 1998-11-16 Porous inorganic particles as carriers for drug substances
US09/214,318 US6558703B1 (en) 1997-11-28 1998-11-18 Porous hydroxyapatite particles as carriers for drug substances
CN98811634A CN1280492A (zh) 1997-11-28 1998-11-19 作为药物载体的多孔羟基磷灰石颗粒
RU2000113731/15A RU2219907C2 (ru) 1997-11-28 1998-11-19 Пористые частицы гидроксиапатита в качестве носителей для лекарственных веществ
IDW20000937A ID24700A (id) 1997-11-28 1998-11-19 Partikel hidroksiapatit berpori sebagai pembawa bahan obat
PT98957268T PT1032370E (pt) 1997-11-28 1998-11-19 Particulas de hidroxiapatite porosas como veiculos para farmacos
SI9830597T SI1032370T1 (en) 1997-11-28 1998-11-19 Porous hydroxyapatite particles as carriers for drug substances
PL98340927A PL340927A1 (en) 1997-11-28 1998-11-19 Porous particles of hydroxyapatite as drug carriers
CA002311780A CA2311780A1 (en) 1997-11-28 1998-11-19 Porous hydroxyapatite particles as carriers for drug substances
DK98957268T DK1032370T3 (da) 1997-11-28 1998-11-19 Porøse hydroxyapatitpartikler som bærere for lægemiddelstoffer
AU13563/99A AU752044B2 (en) 1997-11-28 1998-11-19 Porous hydroxyapatite particles as carriers for drug substances
EP98957268A EP1032370B1 (en) 1997-11-28 1998-11-19 Porous hydroxyapatite particles as carriers for drug substances
NZ504353A NZ504353A (en) 1997-11-28 1998-11-19 Porous greasy or non-greasy hydroxyapatite ceramic particles and a greasy, oily or sticky excipient as carriers for drug substances
HU0100303A HUP0100303A3 (en) 1997-11-28 1998-11-19 Porous hydroxyapatite particles as carriers for drug substances
SK660-2000A SK6602000A3 (en) 1997-11-28 1998-11-19 Porous hydroxyapatite particles as carriers for drug substances
BR9814751-0A BR9814751A (pt) 1997-11-28 1998-11-19 Composição sólida seca para liberação de droga, processo para a preparação da mesma, e, uso de um grande número de partìculas porosas inorgânicas que são compostas de hidroxiapatita de cerâmica.
PCT/SE1998/002089 WO1999027912A1 (en) 1997-11-28 1998-11-19 Porous hydroxyapatite particles as carriers for drug substances
KR1020007005802A KR20010032557A (ko) 1997-11-28 1998-11-19 약물에 대한 담체로서의 다공성 수산화인회석 입자
AT98957268T ATE256453T1 (de) 1997-11-28 1998-11-19 Poröse hydroxyapatit-partikel als träger für medikamente
IL13614698A IL136146A0 (en) 1997-11-28 1998-11-19 Porous hydroxyapatite particles as carriers for drug substances
JP2000522898A JP2001524513A (ja) 1997-11-28 1998-11-19 薬剤物質の担体としての多孔性ハイドロキシアパタイト粒子
ES98957268T ES2210840T3 (es) 1997-11-28 1998-11-19 Particulas porosas de hidroxiapatito como excipientes para medicamentos.
DE69820674T DE69820674T2 (de) 1997-11-28 1998-11-19 Poröse hydroxyapatit-partikel als träger für medikamente
NO20002719A NO20002719L (no) 1997-11-28 2000-05-26 Porøse hydroksyapatittpartilker som bærere for legemiddelsubstanser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9704400A SE9704400D0 (sv) 1997-11-28 1997-11-28 Porous inorganic particles as carriers for drug substances

Publications (1)

Publication Number Publication Date
SE9704400D0 true SE9704400D0 (sv) 1997-11-28

Family

ID=20409177

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9704400A SE9704400D0 (sv) 1997-11-28 1997-11-28 Porous inorganic particles as carriers for drug substances

Country Status (26)

Country Link
US (1) US6558703B1 (cg-RX-API-DMAC7.html)
EP (1) EP1032370B1 (cg-RX-API-DMAC7.html)
JP (1) JP2001524513A (cg-RX-API-DMAC7.html)
KR (1) KR20010032557A (cg-RX-API-DMAC7.html)
CN (1) CN1280492A (cg-RX-API-DMAC7.html)
AR (1) AR016683A1 (cg-RX-API-DMAC7.html)
AT (1) ATE256453T1 (cg-RX-API-DMAC7.html)
AU (1) AU752044B2 (cg-RX-API-DMAC7.html)
BR (1) BR9814751A (cg-RX-API-DMAC7.html)
CA (1) CA2311780A1 (cg-RX-API-DMAC7.html)
DE (1) DE69820674T2 (cg-RX-API-DMAC7.html)
DK (1) DK1032370T3 (cg-RX-API-DMAC7.html)
ES (1) ES2210840T3 (cg-RX-API-DMAC7.html)
HU (1) HUP0100303A3 (cg-RX-API-DMAC7.html)
ID (1) ID24700A (cg-RX-API-DMAC7.html)
IL (1) IL136146A0 (cg-RX-API-DMAC7.html)
NO (1) NO20002719L (cg-RX-API-DMAC7.html)
NZ (1) NZ504353A (cg-RX-API-DMAC7.html)
PL (1) PL340927A1 (cg-RX-API-DMAC7.html)
PT (1) PT1032370E (cg-RX-API-DMAC7.html)
RU (1) RU2219907C2 (cg-RX-API-DMAC7.html)
SE (1) SE9704400D0 (cg-RX-API-DMAC7.html)
SK (1) SK6602000A3 (cg-RX-API-DMAC7.html)
TW (1) TW524694B (cg-RX-API-DMAC7.html)
WO (1) WO1999027912A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA9810463B (cg-RX-API-DMAC7.html)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9924334D0 (en) * 1999-10-15 1999-12-15 Secr Defence Pharmaceutical products and methods of fabrication therefor
BR0109991A (pt) * 2000-04-11 2003-05-27 Sankyo Co Composição farmacêutica
IT1319202B1 (it) 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
US6462021B1 (en) 2000-11-06 2002-10-08 Astrazeneca Ab Use of low molecular weight thrombin inhibitor
CN100513398C (zh) 2002-12-03 2009-07-15 Axys药物公司 作为因子viia抑制剂的2-(2-羟基联苯-3-基)-1h-苯并咪唑-5-甲脒衍生物
KR101207553B1 (ko) 2005-06-02 2012-12-03 (주)씨앤팜 금속 이중층 수산화물을 포함하는 생체 주사제용 약물 담체
TW200806648A (en) * 2005-11-29 2008-02-01 Sankyo Co Acid addition salts of dihydropyridine derivatives
TW200736245A (en) * 2005-11-29 2007-10-01 Sankyo Co Acid addition salts of optically active dihydropyridine derivatives
JP5027410B2 (ja) * 2005-12-13 2012-09-19 株式会社サンギ ユビキノン含有組成物
US20100040668A1 (en) * 2006-01-12 2010-02-18 Rutgers, The State University Of New Jersey Biomimetic Hydroxyapatite Composite Materials and Methods for the Preparation Thereof
US8287914B2 (en) * 2006-01-12 2012-10-16 Rutgers, The State University Of New Jersey Biomimetic hydroxyapatite synthesis
AU2007224651B8 (en) * 2006-03-14 2011-10-27 Lidds Ab Bioresorbable controlled-release composition
GB0909460D0 (en) 2009-06-02 2009-07-15 Intrinsiq Materials Global Ltd Mesoporus material
WO2014120922A1 (en) 2013-02-01 2014-08-07 W. R. Grace & Co.-Conn. Porous silica gel as a carrier for liquid technologies
WO2015040212A1 (en) * 2013-09-20 2015-03-26 Tillotts Pharma Ag Delayed release pharmaceutical formulation
CN104133014B (zh) * 2014-07-16 2015-09-16 广州法尔麦兰药物技术有限公司 一种考察布洛伪麻缓释制剂释放度的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8413191D0 (en) 1984-05-23 1984-06-27 Beecham Group Plc Pharmaceutical composition
GB8713263D0 (en) 1987-06-05 1987-07-08 Unilever Plc Spheroidal silica
EP0376331A3 (en) 1988-12-29 1991-03-13 Asahi Kogaku Kogyo Kabushiki Kaisha Slow release drug delivery granules and process for production thereof
US5149523A (en) * 1989-06-20 1992-09-22 Aktiebolaget Hassle Polystyrenesulfonate-drug complex and solid dosage forms thereof
DE4028906A1 (de) * 1990-09-12 1992-03-19 Paz Arzneimittelentwicklung Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
US5443459A (en) * 1991-01-30 1995-08-22 Alza Corporation Osmotic device for delayed delivery of agent
US5834496A (en) * 1991-12-02 1998-11-10 Sepracor, Inc. Methods for treating hypertension using optically pure S(-) felodipine
US5947893A (en) * 1994-04-27 1999-09-07 Board Of Regents, The University Of Texas System Method of making a porous prothesis with biodegradable coatings
US6096324A (en) * 1995-06-13 2000-08-01 Laboratory Skin Care Methods of delivering materials into the skin, and compositions used therein
JP3562878B2 (ja) * 1995-07-07 2004-09-08 丸尾カルシウム株式会社 花弁状多孔質ヒドロキシアパタイト微粒子及びその製造方法

Also Published As

Publication number Publication date
AU1356399A (en) 1999-06-16
ES2210840T3 (es) 2004-07-01
JP2001524513A (ja) 2001-12-04
EP1032370B1 (en) 2003-12-17
DE69820674D1 (de) 2004-01-29
DE69820674T2 (de) 2004-09-30
CA2311780A1 (en) 1999-06-10
US6558703B1 (en) 2003-05-06
ATE256453T1 (de) 2004-01-15
EP1032370A1 (en) 2000-09-06
DK1032370T3 (da) 2004-03-15
BR9814751A (pt) 2000-10-03
RU2219907C2 (ru) 2003-12-27
WO1999027912A1 (en) 1999-06-10
ID24700A (id) 2000-08-03
AR016683A1 (es) 2001-07-25
KR20010032557A (ko) 2001-04-25
AU752044B2 (en) 2002-09-05
NO20002719D0 (no) 2000-05-26
HUP0100303A3 (en) 2004-03-29
IL136146A0 (en) 2001-05-20
NO20002719L (no) 2000-07-28
NZ504353A (en) 2001-10-26
PT1032370E (pt) 2004-05-31
TW524694B (en) 2003-03-21
CN1280492A (zh) 2001-01-17
HUP0100303A2 (hu) 2001-08-28
ZA9810463B (en) 1999-05-21
PL340927A1 (en) 2001-03-12
SK6602000A3 (en) 2001-01-18

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