BR9814751A - Composição sólida seca para liberação de droga, processo para a preparação da mesma, e, uso de um grande número de partìculas porosas inorgânicas que são compostas de hidroxiapatita de cerâmica. - Google Patents

Composição sólida seca para liberação de droga, processo para a preparação da mesma, e, uso de um grande número de partìculas porosas inorgânicas que são compostas de hidroxiapatita de cerâmica.

Info

Publication number
BR9814751A
BR9814751A BR9814751-0A BR9814751A BR9814751A BR 9814751 A BR9814751 A BR 9814751A BR 9814751 A BR9814751 A BR 9814751A BR 9814751 A BR9814751 A BR 9814751A
Authority
BR
Brazil
Prior art keywords
large number
drug
oily
greasy
solid composition
Prior art date
Application number
BR9814751-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Christer Karlsson
Per Johan Lundberg
Adam Rosinski
Malin Soederbom
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR9814751A publication Critical patent/BR9814751A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/005—Enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BR9814751-0A 1997-11-28 1998-11-19 Composição sólida seca para liberação de droga, processo para a preparação da mesma, e, uso de um grande número de partìculas porosas inorgânicas que são compostas de hidroxiapatita de cerâmica. BR9814751A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704400A SE9704400D0 (sv) 1997-11-28 1997-11-28 Porous inorganic particles as carriers for drug substances
PCT/SE1998/002089 WO1999027912A1 (en) 1997-11-28 1998-11-19 Porous hydroxyapatite particles as carriers for drug substances

Publications (1)

Publication Number Publication Date
BR9814751A true BR9814751A (pt) 2000-10-03

Family

ID=20409177

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9814751-0A BR9814751A (pt) 1997-11-28 1998-11-19 Composição sólida seca para liberação de droga, processo para a preparação da mesma, e, uso de um grande número de partìculas porosas inorgânicas que são compostas de hidroxiapatita de cerâmica.

Country Status (26)

Country Link
US (1) US6558703B1 (cg-RX-API-DMAC7.html)
EP (1) EP1032370B1 (cg-RX-API-DMAC7.html)
JP (1) JP2001524513A (cg-RX-API-DMAC7.html)
KR (1) KR20010032557A (cg-RX-API-DMAC7.html)
CN (1) CN1280492A (cg-RX-API-DMAC7.html)
AR (1) AR016683A1 (cg-RX-API-DMAC7.html)
AT (1) ATE256453T1 (cg-RX-API-DMAC7.html)
AU (1) AU752044B2 (cg-RX-API-DMAC7.html)
BR (1) BR9814751A (cg-RX-API-DMAC7.html)
CA (1) CA2311780A1 (cg-RX-API-DMAC7.html)
DE (1) DE69820674T2 (cg-RX-API-DMAC7.html)
DK (1) DK1032370T3 (cg-RX-API-DMAC7.html)
ES (1) ES2210840T3 (cg-RX-API-DMAC7.html)
HU (1) HUP0100303A3 (cg-RX-API-DMAC7.html)
ID (1) ID24700A (cg-RX-API-DMAC7.html)
IL (1) IL136146A0 (cg-RX-API-DMAC7.html)
NO (1) NO20002719L (cg-RX-API-DMAC7.html)
NZ (1) NZ504353A (cg-RX-API-DMAC7.html)
PL (1) PL340927A1 (cg-RX-API-DMAC7.html)
PT (1) PT1032370E (cg-RX-API-DMAC7.html)
RU (1) RU2219907C2 (cg-RX-API-DMAC7.html)
SE (1) SE9704400D0 (cg-RX-API-DMAC7.html)
SK (1) SK6602000A3 (cg-RX-API-DMAC7.html)
TW (1) TW524694B (cg-RX-API-DMAC7.html)
WO (1) WO1999027912A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA9810463B (cg-RX-API-DMAC7.html)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9924334D0 (en) * 1999-10-15 1999-12-15 Secr Defence Pharmaceutical products and methods of fabrication therefor
BR0109991A (pt) * 2000-04-11 2003-05-27 Sankyo Co Composição farmacêutica
IT1319202B1 (it) 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
US6462021B1 (en) 2000-11-06 2002-10-08 Astrazeneca Ab Use of low molecular weight thrombin inhibitor
CN100513398C (zh) 2002-12-03 2009-07-15 Axys药物公司 作为因子viia抑制剂的2-(2-羟基联苯-3-基)-1h-苯并咪唑-5-甲脒衍生物
KR101207553B1 (ko) 2005-06-02 2012-12-03 (주)씨앤팜 금속 이중층 수산화물을 포함하는 생체 주사제용 약물 담체
TW200806648A (en) * 2005-11-29 2008-02-01 Sankyo Co Acid addition salts of dihydropyridine derivatives
TW200736245A (en) * 2005-11-29 2007-10-01 Sankyo Co Acid addition salts of optically active dihydropyridine derivatives
JP5027410B2 (ja) * 2005-12-13 2012-09-19 株式会社サンギ ユビキノン含有組成物
US20100040668A1 (en) * 2006-01-12 2010-02-18 Rutgers, The State University Of New Jersey Biomimetic Hydroxyapatite Composite Materials and Methods for the Preparation Thereof
US8287914B2 (en) * 2006-01-12 2012-10-16 Rutgers, The State University Of New Jersey Biomimetic hydroxyapatite synthesis
AU2007224651B8 (en) * 2006-03-14 2011-10-27 Lidds Ab Bioresorbable controlled-release composition
GB0909460D0 (en) 2009-06-02 2009-07-15 Intrinsiq Materials Global Ltd Mesoporus material
WO2014120922A1 (en) 2013-02-01 2014-08-07 W. R. Grace & Co.-Conn. Porous silica gel as a carrier for liquid technologies
WO2015040212A1 (en) * 2013-09-20 2015-03-26 Tillotts Pharma Ag Delayed release pharmaceutical formulation
CN104133014B (zh) * 2014-07-16 2015-09-16 广州法尔麦兰药物技术有限公司 一种考察布洛伪麻缓释制剂释放度的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8413191D0 (en) 1984-05-23 1984-06-27 Beecham Group Plc Pharmaceutical composition
GB8713263D0 (en) 1987-06-05 1987-07-08 Unilever Plc Spheroidal silica
EP0376331A3 (en) 1988-12-29 1991-03-13 Asahi Kogaku Kogyo Kabushiki Kaisha Slow release drug delivery granules and process for production thereof
US5149523A (en) * 1989-06-20 1992-09-22 Aktiebolaget Hassle Polystyrenesulfonate-drug complex and solid dosage forms thereof
DE4028906A1 (de) * 1990-09-12 1992-03-19 Paz Arzneimittelentwicklung Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
US5443459A (en) * 1991-01-30 1995-08-22 Alza Corporation Osmotic device for delayed delivery of agent
US5834496A (en) * 1991-12-02 1998-11-10 Sepracor, Inc. Methods for treating hypertension using optically pure S(-) felodipine
US5947893A (en) * 1994-04-27 1999-09-07 Board Of Regents, The University Of Texas System Method of making a porous prothesis with biodegradable coatings
US6096324A (en) * 1995-06-13 2000-08-01 Laboratory Skin Care Methods of delivering materials into the skin, and compositions used therein
JP3562878B2 (ja) * 1995-07-07 2004-09-08 丸尾カルシウム株式会社 花弁状多孔質ヒドロキシアパタイト微粒子及びその製造方法

Also Published As

Publication number Publication date
AU1356399A (en) 1999-06-16
ES2210840T3 (es) 2004-07-01
JP2001524513A (ja) 2001-12-04
EP1032370B1 (en) 2003-12-17
DE69820674D1 (de) 2004-01-29
DE69820674T2 (de) 2004-09-30
CA2311780A1 (en) 1999-06-10
US6558703B1 (en) 2003-05-06
ATE256453T1 (de) 2004-01-15
EP1032370A1 (en) 2000-09-06
DK1032370T3 (da) 2004-03-15
RU2219907C2 (ru) 2003-12-27
WO1999027912A1 (en) 1999-06-10
ID24700A (id) 2000-08-03
AR016683A1 (es) 2001-07-25
SE9704400D0 (sv) 1997-11-28
KR20010032557A (ko) 2001-04-25
AU752044B2 (en) 2002-09-05
NO20002719D0 (no) 2000-05-26
HUP0100303A3 (en) 2004-03-29
IL136146A0 (en) 2001-05-20
NO20002719L (no) 2000-07-28
NZ504353A (en) 2001-10-26
PT1032370E (pt) 2004-05-31
TW524694B (en) 2003-03-21
CN1280492A (zh) 2001-01-17
HUP0100303A2 (hu) 2001-08-28
ZA9810463B (en) 1999-05-21
PL340927A1 (en) 2001-03-12
SK6602000A3 (en) 2001-01-18

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7O E 8O ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1910 DE 14/08/2007.