SE8602449L - 11-beta substituerade steroider och forfarande for deras framstellning - Google Patents
11-beta substituerade steroider och forfarande for deras framstellningInfo
- Publication number
- SE8602449L SE8602449L SE8602449A SE8602449A SE8602449L SE 8602449 L SE8602449 L SE 8602449L SE 8602449 A SE8602449 A SE 8602449A SE 8602449 A SE8602449 A SE 8602449A SE 8602449 L SE8602449 L SE 8602449L
- Authority
- SE
- Sweden
- Prior art keywords
- alkyl
- group
- procedures
- preparation
- alkenyl
- Prior art date
Links
- 150000003431 steroids Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000002431 aminoalkoxy group Chemical group 0.000 abstract 1
- 239000003418 antiprogestin Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 230000003623 progesteronic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003808 silyl group Chemical group [H][Si]([H])([H])[*] 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0074—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858513723A GB8513723D0 (en) | 1985-05-31 | 1985-05-31 | 11-beta substituted steroids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8602449D0 SE8602449D0 (sv) | 1986-05-29 |
| SE8602449L true SE8602449L (sv) | 1986-12-01 |
Family
ID=10579949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8602449A SE8602449L (sv) | 1985-05-31 | 1986-05-29 | 11-beta substituerade steroider och forfarande for deras framstellning |
Country Status (21)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0289073B1 (en) * | 1987-04-24 | 1991-11-27 | Akzo N.V. | Novel 11-aryloestrane and 11-arylpregnane derivatives |
| ATE85342T1 (de) * | 1987-12-12 | 1993-02-15 | Akzo Nv | 11-arylsteroid-derivate. |
| FR2665901B2 (fr) * | 1989-02-24 | 1994-07-29 | Roussel Uclaf | Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments. |
| FR2643638B1 (fr) * | 1989-02-24 | 1991-06-14 | Roussel Uclaf | Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant |
| FR2701262B1 (fr) * | 1993-02-05 | 1995-03-24 | Roussel Uclaf | Nouveau procédé de préparation de stéroïdes 6 alpa, 9 alpha-difluorés et nouveaus intermédiaires. |
| TWI265167B (en) * | 1999-11-29 | 2006-11-01 | Akzo Nobel Nv | 3-methylene steroid derivatives |
| DE19961219A1 (de) * | 1999-12-15 | 2001-07-19 | Jenapharm Gmbh | 11beta-Phenylestratrien-Derivate mit Fluoralkylgruppen in der aromatischen Seitenkette, deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
| TW200531977A (en) | 2004-03-25 | 2005-10-01 | Akzo Nobel Nv | Progesterone receptor modulators |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH488682A (de) * | 1965-07-30 | 1970-04-15 | Ciba Geigy | Verfahren zur Herstellung von 4,9,11-Trienen der 19-Nor-androstanreihe |
| FR205F (enrdf_load_stackoverflow) * | 1965-10-22 | |||
| FR5913M (enrdf_load_stackoverflow) * | 1965-12-02 | 1968-04-01 | ||
| NL128375C (enrdf_load_stackoverflow) * | 1966-02-18 | |||
| FR2054527B1 (enrdf_load_stackoverflow) * | 1969-07-28 | 1973-06-08 | Roussel Uclaf | |
| FR2054525B1 (enrdf_load_stackoverflow) * | 1969-07-28 | 1973-01-12 | Roussel Uclaf | |
| FR2377418A1 (fr) * | 1977-01-13 | 1978-08-11 | Roussel Uclaf | Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments |
| ZA8231B (en) * | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
| FR2522328B1 (fr) * | 1982-03-01 | 1986-02-14 | Roussel Uclaf | Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments |
| AU580843B2 (en) * | 1985-02-07 | 1989-02-02 | Schering Aktiengesellschaft | 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them |
-
1985
- 1985-05-31 GB GB858513723A patent/GB8513723D0/en active Pending
-
1986
- 1986-05-23 ES ES555298A patent/ES8707972A1/es not_active Expired
- 1986-05-27 HU HU862228A patent/HU197925B/hu not_active IP Right Cessation
- 1986-05-27 GB GB08612866A patent/GB2175905B/en not_active Expired
- 1986-05-28 IL IL78957A patent/IL78957A/xx unknown
- 1986-05-28 CH CH2152/86A patent/CH669385A5/de not_active IP Right Cessation
- 1986-05-28 FR FR8607660A patent/FR2582654B1/fr not_active Expired
- 1986-05-28 DE DE19863617883 patent/DE3617883A1/de not_active Withdrawn
- 1986-05-28 NZ NZ216325A patent/NZ216325A/xx unknown
- 1986-05-28 IT IT20598/86A patent/IT1190014B/it active
- 1986-05-28 PT PT82665A patent/PT82665B/pt not_active IP Right Cessation
- 1986-05-29 AU AU58062/86A patent/AU587031B2/en not_active Ceased
- 1986-05-29 SE SE8602449A patent/SE8602449L/ not_active Application Discontinuation
- 1986-05-29 GR GR861405A patent/GR861405B/el unknown
- 1986-05-29 DK DK251386A patent/DK251386A/da not_active Application Discontinuation
- 1986-05-29 NL NL8601387A patent/NL8601387A/nl not_active Application Discontinuation
- 1986-05-29 FI FI862278A patent/FI862278A7/fi not_active Application Discontinuation
- 1986-05-29 SU SU864027509A patent/SU1508963A3/ru active
- 1986-05-30 ZA ZA864065A patent/ZA864065B/xx unknown
- 1986-05-30 BE BE0/216722A patent/BE904846A/fr not_active IP Right Cessation
- 1986-05-30 JP JP61123893A patent/JPS6212796A/ja active Pending
- 1986-05-30 KR KR1019860004283A patent/KR860009035A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| NZ216325A (en) | 1989-01-27 |
| IT8620598A1 (it) | 1987-11-28 |
| BE904846A (fr) | 1986-12-01 |
| FI862278A7 (fi) | 1986-12-01 |
| IL78957A0 (en) | 1986-09-30 |
| IT1190014B (it) | 1988-02-10 |
| FR2582654B1 (fr) | 1988-06-03 |
| FI862278A0 (fi) | 1986-05-29 |
| DK251386D0 (da) | 1986-05-29 |
| ES8707972A1 (es) | 1987-09-01 |
| GB8612866D0 (en) | 1986-07-02 |
| JPS6212796A (ja) | 1987-01-21 |
| PT82665A (en) | 1986-06-01 |
| ES555298A0 (es) | 1987-09-01 |
| HU197925B (en) | 1989-06-28 |
| FR2582654A1 (fr) | 1986-12-05 |
| GB2175905A (en) | 1986-12-10 |
| PT82665B (pt) | 1988-08-17 |
| SE8602449D0 (sv) | 1986-05-29 |
| AU5806286A (en) | 1986-12-04 |
| SU1508963A3 (ru) | 1989-09-15 |
| KR860009035A (ko) | 1986-12-19 |
| ZA864065B (en) | 1987-01-28 |
| GB8513723D0 (en) | 1985-07-03 |
| DK251386A (da) | 1986-12-01 |
| GB2175905B (en) | 1989-01-18 |
| IL78957A (en) | 1990-11-29 |
| HUT44575A (en) | 1988-03-28 |
| IT8620598A0 (it) | 1986-05-28 |
| GR861405B (en) | 1986-09-26 |
| NL8601387A (nl) | 1986-12-16 |
| DE3617883A1 (de) | 1986-12-04 |
| CH669385A5 (enrdf_load_stackoverflow) | 1989-03-15 |
| AU587031B2 (en) | 1989-08-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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