PT82665B - Processo para a preparacao de esteroides 11 beta-substituidos e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de esteroides 11 beta-substituidos e de composicoes farmaceuticas que os contem

Info

Publication number
PT82665B
PT82665B PT82665A PT8266586A PT82665B PT 82665 B PT82665 B PT 82665B PT 82665 A PT82665 A PT 82665A PT 8266586 A PT8266586 A PT 8266586A PT 82665 B PT82665 B PT 82665B
Authority
PT
Portugal
Prior art keywords
esteroids
substituted
pharmaceutical compositions
compositions containing
preparing beta
Prior art date
Application number
PT82665A
Other languages
English (en)
Other versions
PT82665A (en
Inventor
Enrico Di Salle
Franco Faustini
Vittoria Villa
Roberto D Alessio
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of PT82665A publication Critical patent/PT82665A/pt
Publication of PT82665B publication Critical patent/PT82665B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0066Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • C07J21/006Ketals at position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT82665A 1985-05-31 1986-05-28 Processo para a preparacao de esteroides 11 beta-substituidos e de composicoes farmaceuticas que os contem PT82665B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858513723A GB8513723D0 (en) 1985-05-31 1985-05-31 11-beta substituted steroids

Publications (2)

Publication Number Publication Date
PT82665A PT82665A (en) 1986-06-01
PT82665B true PT82665B (pt) 1988-08-17

Family

ID=10579949

Family Applications (1)

Application Number Title Priority Date Filing Date
PT82665A PT82665B (pt) 1985-05-31 1986-05-28 Processo para a preparacao de esteroides 11 beta-substituidos e de composicoes farmaceuticas que os contem

Country Status (21)

Country Link
JP (1) JPS6212796A (pt)
KR (1) KR860009035A (pt)
AU (1) AU587031B2 (pt)
BE (1) BE904846A (pt)
CH (1) CH669385A5 (pt)
DE (1) DE3617883A1 (pt)
DK (1) DK251386A (pt)
ES (1) ES8707972A1 (pt)
FI (1) FI862278A (pt)
FR (1) FR2582654B1 (pt)
GB (2) GB8513723D0 (pt)
GR (1) GR861405B (pt)
HU (1) HU197925B (pt)
IL (1) IL78957A (pt)
IT (1) IT1190014B (pt)
NL (1) NL8601387A (pt)
NZ (1) NZ216325A (pt)
PT (1) PT82665B (pt)
SE (1) SE8602449L (pt)
SU (1) SU1508963A3 (pt)
ZA (1) ZA864065B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3866410D1 (de) * 1987-04-24 1992-01-09 Akzo Nv 11-arylestranderivate und 11-arylpregnanderivate.
ES2053714T3 (es) * 1987-12-12 1994-08-01 Akzo Nv Proceso para la preparacion de 11-arilesteroides.
FR2643638B1 (fr) * 1989-02-24 1991-06-14 Roussel Uclaf Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2665901B2 (fr) * 1989-02-24 1994-07-29 Roussel Uclaf Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments.
TWI265167B (en) * 1999-11-29 2006-11-01 Akzo Nobel Nv 3-methylene steroid derivatives
DE19961219A1 (de) * 1999-12-15 2001-07-19 Jenapharm Gmbh 11beta-Phenylestratrien-Derivate mit Fluoralkylgruppen in der aromatischen Seitenkette, deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
TW200531977A (en) 2004-03-25 2005-10-01 Akzo Nobel Nv Progesterone receptor modulators

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH488682A (de) * 1965-07-30 1970-04-15 Ciba Geigy Verfahren zur Herstellung von 4,9,11-Trienen der 19-Nor-androstanreihe
FR205F (pt) * 1965-10-22
FR5913M (pt) * 1965-12-02 1968-04-01
NL128375C (pt) * 1966-02-18
FR2054527B1 (pt) * 1969-07-28 1973-06-08 Roussel Uclaf
FR2054525B1 (pt) * 1969-07-28 1973-01-12 Roussel Uclaf
FR2377418A1 (fr) * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
FR2522328B1 (fr) * 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments
AU580843B2 (en) * 1985-02-07 1989-02-02 Schering Aktiengesellschaft 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
IT1190014B (it) 1988-02-10
GB8513723D0 (en) 1985-07-03
FR2582654B1 (fr) 1988-06-03
PT82665A (en) 1986-06-01
IL78957A (en) 1990-11-29
DK251386A (da) 1986-12-01
IL78957A0 (en) 1986-09-30
NL8601387A (nl) 1986-12-16
FI862278A (fi) 1986-12-01
HUT44575A (en) 1988-03-28
AU587031B2 (en) 1989-08-03
IT8620598A1 (it) 1987-11-28
GB8612866D0 (en) 1986-07-02
DE3617883A1 (de) 1986-12-04
AU5806286A (en) 1986-12-04
DK251386D0 (da) 1986-05-29
BE904846A (fr) 1986-12-01
CH669385A5 (pt) 1989-03-15
SE8602449L (sv) 1986-12-01
HU197925B (en) 1989-06-28
SU1508963A3 (ru) 1989-09-15
NZ216325A (en) 1989-01-27
FI862278A0 (fi) 1986-05-29
SE8602449D0 (sv) 1986-05-29
KR860009035A (ko) 1986-12-19
ES8707972A1 (es) 1987-09-01
ZA864065B (en) 1987-01-28
ES555298A0 (es) 1987-09-01
FR2582654A1 (fr) 1986-12-05
JPS6212796A (ja) 1987-01-21
IT8620598A0 (it) 1986-05-28
GR861405B (en) 1986-09-26
GB2175905B (en) 1989-01-18
GB2175905A (en) 1986-12-10

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MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19920831