ZA864065B - 11-beta substituted steroids and process for their preparation - Google Patents

11-beta substituted steroids and process for their preparation

Info

Publication number
ZA864065B
ZA864065B ZA864065A ZA864065A ZA864065B ZA 864065 B ZA864065 B ZA 864065B ZA 864065 A ZA864065 A ZA 864065A ZA 864065 A ZA864065 A ZA 864065A ZA 864065 B ZA864065 B ZA 864065B
Authority
ZA
South Africa
Prior art keywords
preparation
substituted steroids
beta substituted
beta
steroids
Prior art date
Application number
ZA864065A
Inventor
Franco Faustini
Roberto D Alessio
Vittoria Villa
Enrico Di Salle
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of ZA864065B publication Critical patent/ZA864065B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA864065A 1985-05-31 1986-05-30 11-beta substituted steroids and process for their preparation ZA864065B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858513723A GB8513723D0 (en) 1985-05-31 1985-05-31 11-beta substituted steroids

Publications (1)

Publication Number Publication Date
ZA864065B true ZA864065B (en) 1987-01-28

Family

ID=10579949

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA864065A ZA864065B (en) 1985-05-31 1986-05-30 11-beta substituted steroids and process for their preparation

Country Status (21)

Country Link
JP (1) JPS6212796A (en)
KR (1) KR860009035A (en)
AU (1) AU587031B2 (en)
BE (1) BE904846A (en)
CH (1) CH669385A5 (en)
DE (1) DE3617883A1 (en)
DK (1) DK251386A (en)
ES (1) ES8707972A1 (en)
FI (1) FI862278A (en)
FR (1) FR2582654B1 (en)
GB (2) GB8513723D0 (en)
GR (1) GR861405B (en)
HU (1) HU197925B (en)
IL (1) IL78957A (en)
IT (1) IT1190014B (en)
NL (1) NL8601387A (en)
NZ (1) NZ216325A (en)
PT (1) PT82665B (en)
SE (1) SE8602449L (en)
SU (1) SU1508963A3 (en)
ZA (1) ZA864065B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3866410D1 (en) * 1987-04-24 1992-01-09 Akzo Nv 11-ARYLESTRANDERIVATIVES AND 11-ARYLPREGNANDERIVATIVES.
ES2053714T3 (en) * 1987-12-12 1994-08-01 Akzo Nv PROCESS FOR THE PREPARATION OF 11-ARILESTEROIDES.
FR2643638B1 (en) * 1989-02-24 1991-06-14 Roussel Uclaf NOVEL 19-NOR STEROIDS HAVING IN THE 11BETA POSITION A CARBON CHAIN COMPRISING AN AMIDE OR CARBAMATE FUNCTION, THEIR PREPARATION METHOD AND INTERMEDIATES THEREOF, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2665901B2 (en) * 1989-02-24 1994-07-29 Roussel Uclaf NEW 19-NOR STEROUIDES HAVING IN THE 11BETA POSITION A CARBON CHAIN COMPRISING AN AMIDE FUNCTION, THEIR PREPARATION, THEIR APPLICATION AS MEDICAMENTS.
TWI265167B (en) * 1999-11-29 2006-11-01 Akzo Nobel Nv 3-methylene steroid derivatives
DE19961219A1 (en) * 1999-12-15 2001-07-19 Jenapharm Gmbh 11beta-phenyltratriene derivatives with fluoroalkyl groups in the aromatic side chain, their preparation and pharmaceutical compositions containing these compounds
TW200531977A (en) 2004-03-25 2005-10-01 Akzo Nobel Nv Progesterone receptor modulators

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH488682A (en) * 1965-07-30 1970-04-15 Ciba Geigy Process for the preparation of 4,9,11-trienes of the 19-nor-androstane series
FR205F (en) * 1965-10-22
FR5913M (en) * 1965-12-02 1968-04-01
NL128375C (en) * 1966-02-18
FR2054527B1 (en) * 1969-07-28 1973-06-08 Roussel Uclaf
FR2054525B1 (en) * 1969-07-28 1973-01-12 Roussel Uclaf
FR2377418A1 (en) * 1977-01-13 1978-08-11 Roussel Uclaf NEW 4,9-DIENIC 11B-SUBSTITUTE STEROID DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
FR2522328B1 (en) * 1982-03-01 1986-02-14 Roussel Uclaf NEW PRODUCTS DERIVED FROM THE STRUCTURE 3-CETO 4,9 19-NOR STEROIDS, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
AU580843B2 (en) * 1985-02-07 1989-02-02 Schering Aktiengesellschaft 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
IT1190014B (en) 1988-02-10
GB8513723D0 (en) 1985-07-03
FR2582654B1 (en) 1988-06-03
PT82665A (en) 1986-06-01
IL78957A (en) 1990-11-29
DK251386A (en) 1986-12-01
IL78957A0 (en) 1986-09-30
NL8601387A (en) 1986-12-16
FI862278A (en) 1986-12-01
HUT44575A (en) 1988-03-28
AU587031B2 (en) 1989-08-03
IT8620598A1 (en) 1987-11-28
GB8612866D0 (en) 1986-07-02
DE3617883A1 (en) 1986-12-04
AU5806286A (en) 1986-12-04
DK251386D0 (en) 1986-05-29
BE904846A (en) 1986-12-01
CH669385A5 (en) 1989-03-15
SE8602449L (en) 1986-12-01
HU197925B (en) 1989-06-28
SU1508963A3 (en) 1989-09-15
NZ216325A (en) 1989-01-27
FI862278A0 (en) 1986-05-29
SE8602449D0 (en) 1986-05-29
KR860009035A (en) 1986-12-19
ES8707972A1 (en) 1987-09-01
PT82665B (en) 1988-08-17
ES555298A0 (en) 1987-09-01
FR2582654A1 (en) 1986-12-05
JPS6212796A (en) 1987-01-21
IT8620598A0 (en) 1986-05-28
GR861405B (en) 1986-09-26
GB2175905B (en) 1989-01-18
GB2175905A (en) 1986-12-10

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